› › Structure analysis

Crystal Structure Analysis of LeuT complexed with L-leucine, sodium and desipramine

X-ray diffraction
1.9Å resolution
PDB entry 2qb4 coloured by chain, front view.
PDB entry 2qb4 coloured by chain, side view.
PDB entry 2qb4 coloured by chain, top view.
Source organism: Aquifex aeolicus VF5
Assemblies composition:
monomeric (preferred)
homo dimer
Entry contents: 1 distinct polypeptide molecule

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: Na(+):neurotransmitter symporter (Snf family)
hide full assembly name
Multimeric state: monomeric
Accessible surface area: 20446.72 Ã…2
Buried surface area: 3171.04 Ã…2
Dissociation area: 0 Ã…2
Dissociation energy (ΔGdiss): 0 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-130575
Assembly 2
Download    3D Visualisation
Assembly Name: Na(+):neurotransmitter symporter (Snf family)
hide full assembly name
Multimeric state: homo dimer
Accessible surface area: 36589.91 Ã…2
Buried surface area: 10648.13 Ã…2
Dissociation area: 2,152.71 Ã…2
Dissociation energy (ΔGdiss): -4.95 kcal/mol
Dissociation entropy (TΔSdiss): 14.87 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-130578

Macromolecules

Na(+):neurotransmitter symporter (Snf family)
Chain: A
Length: 519 amino acids
Theoretical weight: 58.08 KDa
Source organism: Aquifex aeolicus VF5
Expression system: Escherichia coli
UniProt:
  • Canonical: O67854 (Residues: 1-513; Coverage: 100%)
Gene names: aq_2077, snf
Pfam: Sodium:neurotransmitter symporter family
InterPro:
SCOP: SNF-like
Na(+):neurotransmitter symporter (Snf family) in PDB entry 2qb4, assembly 1, front view.
Na(+):neurotransmitter symporter (Snf family) in PDB entry 2qb4, assembly 1, side view.
Na(+):neurotransmitter symporter (Snf family) in PDB entry 2qb4, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links