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Crystal Structure Analysis of LeuT complexed with L-leucine, sodium and desipramine

Source organism: Aquifex aeolicus VF5
Biochemical function: not assigned
Biological process: sodium ion transmembrane transport
Cellular component: membrane

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GO terms

Biochemical function:
  • not assigned
Biological process:
Cellular component:

Sequence family

Pfam Protein family (Pfam)
PF00209
Domain description: Sodium:neurotransmitter symporter family
Occurring in:
  1. Na(+):neurotransmitter symporter (Snf family)
The deposited structure of PDB entry 2qb4 contains 2 copies of Pfam domain PF00209 (Sodium:neurotransmitter symporter family) in Na(+):neurotransmitter symporter (Snf family). Showing 2 copies in chain A.

InterPro InterPro annotations
IPR000175
Domain description: Sodium:neurotransmitter symporter
Occurring in:
  1. Na(+):neurotransmitter symporter (Snf family)
IPR037272
Domain description: Sodium:neurotransmitter symporter superfamily
Occurring in:
  1. Na(+):neurotransmitter symporter (Snf family)

Structure domain

SCOP SCOP annotation
161071
Class: Membrane and cell surface proteins and peptides
Fold: SNF-like
Superfamily: SNF-like
Occurring in:
  1. Na(+):neurotransmitter symporter (Snf family)
The deposited structure of PDB entry 2qb4 contains 1 copy of SCOP domain 161071 (SNF-like) in Na(+):neurotransmitter symporter (Snf family). Showing 1 copy in chain A.

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