› › Structure analysis

Crystal Structure of a Taiwan Habu Venom Metalloproteinase complexed with its endogenous inhibitor pENW

X-ray diffraction
1.37Å resolution
PDB entry 1kug coloured by chain, front view.
PDB entry 1kug coloured by chain, side view.
PDB entry 1kug coloured by chain, top view.
Source organism: Protobothrops mucrosquamatus
Assemblies composition:
hetero dimer (preferred)
hetero tetramer
Entry contents: 2 distinct polypeptide molecules

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: Snake venom metalloproteinase TM-3 and peptide
hide full assembly name
Multimeric state: hetero dimer
Accessible surface area: 9254.19 Ã…2
Buried surface area: 1889.71 Ã…2
Dissociation area: 418.6 Ã…2
Dissociation energy (ΔGdiss): 3.29 kcal/mol
Dissociation entropy (TΔSdiss): 5.05 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-129590
Assembly 2
Download    3D Visualisation
Assembly Name: Snake venom metalloproteinase TM-3 and peptide
hide full assembly name
Multimeric state: hetero tetramer
Accessible surface area: 18299.11 Ã…2
Buried surface area: 3881.63 Ã…2
Dissociation area: 220.18 Ã…2
Dissociation energy (ΔGdiss): 1.17 kcal/mol
Dissociation entropy (TΔSdiss): 15.78 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-129593

Macromolecules

Snake venom metalloproteinase TM-3
Chain: A
Length: 203 amino acids
Theoretical weight: 23.36 KDa
Source organism: Protobothrops mucrosquamatus
UniProt:
  • Canonical: O57413 (Residues: 190-392; Coverage: 44%)
Pfam: Reprolysin (M12B) family zinc metalloprotease
InterPro:
CATH: Collagenase (Catalytic Domain)
SCOP: Reprolysin-like
Snake venom metalloproteinase TM-3 in PDB entry 1kug, assembly 1, front view.
Snake venom metalloproteinase TM-3 in PDB entry 1kug, assembly 1, side view.
Snake venom metalloproteinase TM-3 in PDB entry 1kug, assembly 1, top view.
Molecule details ›

Search similar proteins

ENW
Chain: B
Length: 3 amino acids
Theoretical weight: 429 Da
Source organism: Protobothrops mucrosquamatus
Expression system: Not provided
ENW in PDB entry 1kug, assembly 1, front view.
ENW in PDB entry 1kug, assembly 1, side view.
ENW in PDB entry 1kug, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links