Articles

Making Protein

Making Protein

The human genome codes for 20-25,000 proteins. The lab workhorse bacterium, E.coli, codes for around 2,300.

Opening a Gate to Human Health

Opening a Gate to Human Health

In the 1970s, an exciting discovery of a family of medicines was made by the Japanese scientist Satoshi ÅŒmura. It is one of these molecules which features in the October image in our 2017 calendar.

Thioredoxin - a small protein with a radical role

Thioredoxin - a small protein with a radical role

Turning cartwheels

Turning cartwheels

The image from our 2017 calendar for August is inspired by a molecular cartwheel which is essential for the mobility of single celled parasites called trypanosomes.

Focusing on Crystallin

Focusing on Crystallin

As you read the words on this page, the light enters your eyes and the eye lens focuses it on the retina. From here the image is sent to your brain for processing.

Crystallography from the guts of a cockroach

Crystallography from the guts of a cockroach

DHFR- a target for TB drugs?

DHFR- a target for TB drugs?

This month’s featured structure from our 2017 calendar is the enzyme dihydrofolate reductase (DHFR) from the bacterium that causes tuberculosis (TB), Mycobacterium tuberculosis. DHFR is an essential enzyme for life as it re

Giardia kinesin- a model locomotive

Giardia kinesin- a model locomotive

The March image in our 2017 calendar is that of the parasite Giardia, responsible for the water-borne disease giardiasis.

Zika virus- one year on

Zika virus- one year on

First isolated in the Zika Forest of Uganda in 1947, the image in our 2017 calendar for February is that of Zika virus.

Ebola GP fusion loop

Ebola GP fusion loop

This featured structure explores the molecule from PDBe’s 2017 calendar for January.

Christmas Lights

Christmas Lights

“Marley's face�, wrote Charles Dickens in his novella A Christmas Carol, �... had a dismal light about it, like a bad lobster in a dark cellar.�

Audrey Stevens' Eponymous Protein

Audrey Stevens' Eponymous Protein

On 21st July 1932, on a farm in Nebraska, Audrey Stevens was born. One of the proteins she isolated during her career would be named after her and in 2001, only nine years before her death, its three dimensional structure would be determined.