In October 2014, PDBe hosted the first workshop of the wwPDB Hybrid/Integrative Methods Task Force at ÀÖÌìÌÃÓÎÏ·ÍøÕ¾ (see and ). The initial recommendations of this task force have now been published in a white paper.
ÌýÌý
The main recommendations are:
- In addition to archiving the models themselves, all relevant experimental data and metadata as well as experimental and computational protocols should be archived; inclusivity is key.
- A flexible model representation needs to be developed, allowing for multi-scale models, multi-state models, ensembles of models, and models related by time or other order.
- Procedures for estimating the uncertainty of integrative models should be developed, validated, and adopted.
- A federated system of model and data archives should be created.
- Publication standards for integrative models should be established.
It is now up to the international community (including researchers, archives, journals and funders) to implement these recommendations.
