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Structure of the mechanically activated ion channel Piezo1

Source organism: Mus musculus
Biochemical function: mechanosensitive monoatomic ion channel activity
Biological process: not assigned
Cellular component: membrane

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GO terms

Biochemical function:
Biological process:
  • not assigned
Cellular component:

Sequence families

Pfam Protein families (Pfam)
PF12166
Domain description: Piezo non-specific cation channel, cap domain
Occurring in:
  1. Piezo-type mechanosensitive ion channel component 1
The deposited structure of PDB entry 6bpz contains 3 copies of Pfam domain PF12166 (Piezo non-specific cation channel, R-Ras-binding domain) in Piezo-type mechanosensitive ion channel component 1. Showing 1 copy in chain A.

PF15917
Domain description: Piezo TM25-28
Occurring in:
  1. Piezo-type mechanosensitive ion channel component 1
The deposited structure of PDB entry 6bpz contains 3 copies of Pfam domain PF15917 (Piezo) in Piezo-type mechanosensitive ion channel component 1. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR031334
Domain description: Piezo non-specific cation channel, cap domain
Occurring in:
  1. Piezo-type mechanosensitive ion channel component 1
IPR031805
Domain description: Piezo, TM25-28
Occurring in:
  1. Piezo-type mechanosensitive ion channel component 1
IPR027272
Domain description: Piezo family
Occurring in:
  1. Piezo-type mechanosensitive ion channel component 1

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