1j1e › Citations

Structure of the core domain of human cardiac troponin in the Ca(2+)-saturated form.

Takeda S, Yamashita A, Maeda K, Ma茅da Y
Nature 424 35-41 (2003)
Cited: 490 times
EuropePMC logo PMID:
doi logo

Abstract

Troponin is essential in Ca(2+) regulation of skeletal and cardiac muscle contraction. It consists of three subunits (TnT, TnC and TnI) and, together with tropomyosin, is located on the actin filament. Here we present crystal structures of the core domains (relative molecular mass of 46,000 and 52,000) of human cardiac troponin in the Ca(2+)-saturated form. Analysis of the four-molecule structures reveals that the core domain is further divided into structurally distinct subdomains that are connected by flexible linkers, making the entire molecule highly flexible. The alpha-helical coiled-coil formed between TnT and TnI is integrated in a rigid and asymmetric structure (about 80 angstrom long), the IT arm, which bridges putative tropomyosin-anchoring regions. The structures of the troponin ternary complex imply that Ca(2+) binding to the regulatory site of TnC removes the carboxy-terminal portion of TnI from actin, thereby altering the mobility and/or flexibility of troponin and tropomyosin on the actin filament.

Reviews - 1j1e mentioned but not cited (15)

  1. Tardiff JC. Circ Res 108 765-782 (2011)
  2. Sheng JJ, Jin JP. Gene 576 385-394 (2016)
  3. Li MX, Hwang PM. Gene 571 153-166 (2015)
  4. Johnston JR, Chase PB, Pinto JR. Oncotarget 9 1461-1482 (2018)
  5. Li MX, Robertson IM, Sykes BD. Biochem Biophys Res Commun 369 88-99 (2008)
  6. Cheng Y, Regnier M. Arch Biochem Biophys 601 11-21 (2016)
  7. Cai F, Li MX, Pineda-Sanabria SE, Gelozia S, Lindert S, West F, Sykes BD, Hwang PM. J Mol Cell Cardiol 101 134-144 (2016)
  8. Marques MA, de Oliveira GA. Front Physiol 7 429 (2016)
  9. Metskas LA, Rhoades E. J Mol Biol 428 2965-2977 (2016)
  10. Chavez JD, Wippel HH, Tang X, Keller A, Bruce JE. Chem Rev 122 7647-7689 (2022)
  11. Thompson BR, Metzger JM. Anat Rec (Hoboken) 297 1663-1669 (2014)
  12. Dewan S, McCabe KJ, Regnier M, McCulloch AD. Front Physiol 8 151 (2017)
  13. Kachooei E, Cordina NM, Brown LJ. Biophys Rev 11 621-639 (2019)
  14. Marques MA, Parvatiyar MS, Yang W, de Oliveira GAP, Pinto JR. Arch Biochem Biophys 663 95-100 (2019)
  15. Szikora S, G枚r枚g P, Mih谩ly J. Int J Mol Sci 23 5306 (2022)

Articles - 1j1e mentioned but not cited (67)

  1. Vinogradova MV, Stone DB, Malanina GG, Karatzaferi C, Cooke R, Mendelson RA, Fletterick RJ. Proc Natl Acad Sci U S A 102 5038-5043 (2005)
  2. Ribeiro Ede A, Pinotsis N, Ghisleni A, Salmazo A, Konarev PV, Kostan J, Sj枚blom B, Schreiner C, Polyansky AA, Gkougkoulia EA, Holt MR, Aachmann FL, Zagrovi膰 B, Bordignon E, Pirker KF, Svergun DI, Gautel M, Djinovi膰-Carugo K. Cell 159 1447-1460 (2014)
  3. Yamada Y, Namba K, Fujii T. Nat Commun 11 153 (2020)
  4. Davis JP, Norman C, Kobayashi T, Solaro RJ, Swartz DR, Tikunova SB. Biophys J 92 3195-3206 (2007)
  5. Pinto JR, Parvatiyar MS, Jones MA, Liang J, Ackerman MJ, Potter JD. J Biol Chem 284 19090-19100 (2009)
  6. Manning EP, Tardiff JC, Schwartz SD. Biochemistry 50 7405-7413 (2011)
  7. Chavez JD, Lee CF, Caudal A, Keller A, Tian R, Bruce JE. Cell Syst 6 136-141.e5 (2018)
  8. Khan S, Vihinen M. BMC Struct Biol 7 56 (2007)
  9. Sommese RF, Nag S, Sutton S, Miller SM, Spudich JA, Ruppel KM. PLoS One 8 e83403 (2013)
  10. Cheng Y, Lindert S, Kekenes-Huskey P, Rao VS, Solaro RJ, Rosevear PR, Amaro R, McCulloch AD, McCammon JA, Regnier M. Biophys J 107 1675-1685 (2014)
  11. Tikunova SB, Liu B, Swindle N, Little SC, Gomes AV, Swartz DR, Davis JP. Biochemistry 49 1975-1984 (2010)
  12. Lindert S, Cheng Y, Kekenes-Huskey P, Regnier M, McCammon JA. Biophys J 108 395-407 (2015)
  13. Metskas LA, Rhoades E. J Am Chem Soc 137 11962-11969 (2015)
  14. Manning EP, Tardiff JC, Schwartz SD. J Mol Biol 421 54-66 (2012)
  15. Tadepalli S, Kuang Z, Jiang Q, Liu KK, Fisher MA, Morrissey JJ, Kharasch ED, Slocik JM, Naik RR, Singamaneni S. Sci Rep 5 16206 (2015)
  16. Kekenes-Huskey PM, Lindert S, McCammon JA. PLoS Comput Biol 8 e1002777 (2012)
  17. Jayasundar JJ, Xing J, Robinson JM, Cheung HC, Dong WJ. PLoS One 9 e87135 (2014)
  18. Gangadharan B, Sunitha MS, Mukherjee S, Chowdhury RR, Haque F, Sekar N, Sowdhamini R, Spudich JA, Mercer JA. Proc Natl Acad Sci U S A 114 11115-11120 (2017)
  19. Mathur MC, Kobayashi T, Chalovich JM. Biophys J 94 542-549 (2008)
  20. Stevens CM, Rayani K, Singh G, Lotfalisalmasi B, Tieleman DP, Tibbits GF. J Biol Chem 292 11915-11926 (2017)
  21. Pinto JR, Reynaldo DP, Parvatiyar MS, Dweck D, Liang J, Jones MA, Sorenson MM, Potter JD. J Biol Chem 286 1005-1013 (2011)
  22. Liu B, Lee RS, Biesiadecki BJ, Tikunova SB, Davis JP. J Biol Chem 287 20027-20036 (2012)
  23. Oleszczuk M, Robertson IM, Li MX, Sykes BD. J Mol Cell Cardiol 48 925-933 (2010)
  24. Parvatiyar MS, Pinto JR, Liang J, Potter JD. J Biol Chem 285 27785-27797 (2010)
  25. Sfichi-Duke L, Garcia-Cazarin ML, Sumandea CA, Sievert GA, Balke CW, Zhan DY, Morimoto S, Sumandea MP. J Mol Cell Cardiol 48 934-942 (2010)
  26. Brunet NM, Chase PB, Mihajlovi膰 G, Schoffstall B. Arch Biochem Biophys 552-553 11-20 (2014)
  27. Sevrieva I, Knowles AC, Kampourakis T, Sun YB. J Mol Cell Cardiol 75 181-187 (2014)
  28. Bowman JD, Lindert S. J Phys Chem B 122 7874-7883 (2018)
  29. Dewan S, McCabe KJ, Regnier M, McCulloch AD, Lindert S. J Phys Chem B 120 8264-8275 (2016)
  30. Joosten K, Cohen SX, Emsley P, Mooij W, Lamzin VS, Perrakis A. Acta Crystallogr D Biol Crystallogr 64 416-424 (2008)
  31. Gross SM, Lehman SL. PLoS One 8 e69110 (2013)
  32. Palpant NJ, Houang EM, Delport W, Hastings KE, Onufriev AV, Sham YY, Metzger JM. Physiol Genomics 42 287-299 (2010)
  33. Marques MA, Pinto JR, Moraes AH, Iqbal A, de Magalh茫es MT, Monteiro J, Pedrote MM, Sorenson MM, Silva JL, de Oliveira GA. J Biol Chem 292 2379-2394 (2017)
  34. Ashaduzzaman M, Deshpande SR, Murugan NA, Mishra YK, Turner AP, Tiwari A. Sci Rep 7 44027 (2017)
  35. Robinson JM, Cheung HC, Dong W. Biophys J 95 4772-4789 (2008)
  36. Badr MA, Pinto JR, Davidson MW, Chase PB. PLoS One 11 e0164222 (2016)
  37. Johnston JR, Landim-Vieira M, Marques MA, de Oliveira GAP, Gonzalez-Martinez D, Moraes AH, He H, Iqbal A, Wilnai Y, Birk E, Zucker N, Silva JL, Chase PB, Pinto JR. J Biol Chem 294 20054-20069 (2019)
  38. Aprahamian ML, Tikunova SB, Price MV, Cuesta AF, Davis JP, Lindert S. J Chem Inf Model 57 3056-3069 (2017)
  39. Stevens CM, Rayani K, Genge CE, Singh G, Liang B, Roller JM, Li C, Li AY, Tieleman DP, van Petegem F, Tibbits GF. Biophys J 111 38-49 (2016)
  40. Robertson IM, Holmes PC, Li MX, Pineda-Sanabria SE, Baryshnikova OK, Sykes BD. J Biol Chem 287 4996-5007 (2012)
  41. Pineda-Sanabria SE, Robertson IM, Sun YB, Irving M, Sykes BD. J Mol Cell Cardiol 92 174-184 (2016)
  42. Wang H, Chalovich JM, Marriott G. PLoS One 7 e50420 (2012)
  43. Wong S, Feng HZ, Jin JP. J Mol Cell Cardiol 136 42-52 (2019)
  44. Palpant NJ, Houang EM, Sham YY, Metzger JM. Biophys J 102 1570-1579 (2012)
  45. Ramachandran G, Kumar M, Selvi Rani D, Annanthapur V, Calambur N, Nallari P, Kaur P. PLoS One 8 e70704 (2013)
  46. Schlecht W, Li KL, Hu D, Dong W. Chem Biol Drug Des 87 171-181 (2016)
  47. Thompson BR, Houang EM, Sham YY, Metzger JM. Biophys J 106 2105-2114 (2014)
  48. Zhou Z, Rieck D, Li KL, Ouyang Y, Dong WJ. Arch Biochem Biophys 535 56-67 (2013)
  49. Matsuo T, Takeda S, Oda T, Fujiwara S. Biophys Physicobiol 12 145-158 (2015)
  50. van de Locht M, Donkervoort S, de Winter JM, Conijn S, Begthel L, Kusters B, Mohassel P, Hu Y, Medne L, Quinn C, Moore SA, Foley AR, Seo G, Hwee DT, Malik FI, Irving T, Ma W, Granzier HL, Kamsteeg EJ, Immadisetty K, Kekenes-Huskey P, Pinto JR, Voermans N, B枚nnemann CG, Ottenheijm CA. J Clin Invest 131 145700 (2021)
  51. Marques MA, Landim-Vieira M, Moraes AH, Sun B, Johnston JR, Dieseldorff Jones KM, Cino EA, Parvatiyar MS, Valera IC, Silva JL, Galkin VE, Chase PB, Kekenes-Huskey PM, de Oliveira GAP, Pinto JR. Chem Sci 12 7308-7323 (2021)
  52. Gross SM, Lehman SL. Physiol Genomics 48 377-387 (2016)
  53. Shafaattalab S, Li AY, Lin E, Stevens CM, Dewar LJ, Lynn FC, Sanatani S, Laksman Z, Morin RD, van Petegem F, Hove-Madsen L, Tieleman DP, Davis JP, Tibbits GF. Proc Natl Acad Sci U S A 116 6969-6974 (2019)
  54. Vetter AD, Houang EM, Sell JJ, Thompson BR, Sham YY, Metzger JM. Biophys J 114 1646-1656 (2018)
  55. Pan S, Sommese RF, Sallam KI, Nag S, Sutton S, Miller SM, Spudich JA, Ruppel KM, Ashley EA. BMC Med Genet 16 97 (2015)
  56. Swindle N, Albury AN, Baroud B, Burney M, Tikunova SB. Arch Biochem Biophys 548 46-53 (2014)
  57. Ding WH, Han L, Xiao YY, Mo Y, Yang J, Wang XF, Jin M. Chin Med J (Engl) 130 2823-2828 (2017)
  58. Sitkov N, Zimina T, Kolobov A, Karasev V, Romanov A, Luchinin V, Kaplun D. Micromachines (Basel) 12 691 (2021)
  59. Shakur R, Ochoa JP, Robinson AJ, Niroula A, Chandran A, Rahman T, Vihinen M, Monserrat L. NPJ Genom Med 6 47 (2021)
  60. Yamaguchi M, Kimura M, Ohno T, Nakahara N, Akiyama N, Takemori S, Yagi N. Int J Mol Sci 21 E3520 (2020)
  61. Genchev GZ, Kobayashi M, Kobayashi T, Lu H. FEBS Open Bio 11 1841-1853 (2021)
  62. Sethe Burgie E, Bingman CA, Makino S, Wesenberg GE, Pan X, Fox BG, Phillips GN. Proteins 79 1329-1336 (2011)
  63. Parijat P, Ponnam S, Attili S, Campbell KS, El-Mezgueldi M, Pfuhl M, Kampourakis T. Sci Rep 13 5216 (2023)
  64. Letter Gonzalez-Rayas JM, Hernandez-Hernandez JA, Lopez-Sanchez RDC, Rayas-Gomez AL, Gonzalez-Yanez JM. Arq Bras Cardiol 118 778-782 (2022)
  65. Chapman EA, Roberts DS, Tiambeng TN, Andrews J, Wang MD, Reasoner EA, Melby JA, Li BH, Kim D, Alpert AJ, Jin S, Ge Y. Nat Commun 14 8400 (2023)
  66. research-article Ge Y, Chapman E, Roberts D, Tiambeng T, Andrews J, Wang MD, Reasoner E, Melby J, Li B, Kim D, Alpert A, Jin S. Res Sq rs.3.rs-3108087 (2023)
  67. Yan C, Sack JS. Acta Crystallogr F Struct Biol Commun 78 17-24 (2022)


Reviews citing this publication (89)

  1. Babuin L, Jaffe AS. CMAJ 173 1191-1202 (2005)
  2. Kobayashi T, Solaro RJ. Annu Rev Physiol 67 39-67 (2005)
  3. Grabarek Z. J Mol Biol 359 509-525 (2006)
  4. Bhattacharya S, Bunick CG, Chazin WJ. Biochim Biophys Acta 1742 69-79 (2004)
  5. Willott RH, Gomes AV, Chang AN, Parvatiyar MS, Pinto JR, Potter JD. J Mol Cell Cardiol 48 882-892 (2010)
  6. Apostolovic B, Danial M, Klok HA. Chem Soc Rev 39 3541-3575 (2010)
  7. Tardiff JC. Heart Fail Rev 10 237-248 (2005)
  8. Metzger JM, Westfall MV. Circ Res 94 146-158 (2004)
  9. Parmacek MS, Solaro RJ. Prog Cardiovasc Dis 47 159-176 (2004)
  10. Wei B, Jin JP. Arch Biochem Biophys 505 144-154 (2011)
  11. Li MX, Wang X, Sykes BD. J Muscle Res Cell Motil 25 559-579 (2004)
  12. Wei B, Jin JP. Gene 582 1-13 (2016)
  13. Solaro RJ, Rosevear P, Kobayashi T. Biochem Biophys Res Commun 369 82-87 (2008)
  14. Zhang H, Ge Y. Circ Cardiovasc Genet 4 711 (2011)
  15. Solaro RJ, Henze M, Kobayashi T. Circ Res 112 355-366 (2013)
  16. Garg P, Morris P, Fazlanie AL, Vijayan S, Dancso B, Dastidar AG, Plein S, Mueller C, Haaf P. Intern Emerg Med 12 147-155 (2017)
  17. Solaro RJ, Kobayashi T. J Biol Chem 286 9935-9940 (2011)
  18. Grabarek Z. Biochim Biophys Acta 1813 913-921 (2011)
  19. Gomes AV, Potter JD. Ann N Y Acad Sci 1015 214-224 (2004)
  20. Bains G, Patel AB, Narayanaswami V. Molecules 16 7909-7935 (2011)
  21. Hwang PM, Sykes BD. Nat Rev Drug Discov 14 313-328 (2015)
  22. Sumandea MP, Burkart EM, Kobayashi T, De Tombe PP, Solaro RJ. Ann N Y Acad Sci 1015 39-52 (2004)
  23. Sorsa T, Pollesello P, Solaro RJ. Mol Cell Biochem 266 87-107 (2004)
  24. Westermann D, Neumann JT, S枚rensen NA, Blankenberg S. Nat Rev Cardiol 14 472-483 (2017)
  25. Davis JP, Tikunova SB. Cardiovasc Res 77 619-626 (2008)
  26. Fathil MF, Md Arshad MK, Gopinath SC, Hashim U, Adzhri R, Ayub RM, Ruslinda AR, Nuzaihan M N M, Azman AH, Zaki M, Tang TH. Biosens Bioelectron 70 209-220 (2015)
  27. Leuschner F, Katus HA, Kaya Z. J Autoimmun 33 282-289 (2009)
  28. Marston S, Zamora JE. J Muscle Res Cell Motil 41 71-89 (2020)
  29. Kobirumaki-Shimozawa F, Inoue T, Shintani SA, Oyama K, Terui T, Minamisawa S, Ishiwata S, Fukuda N. J Physiol Sci 64 221-232 (2014)
  30. Negahdaripour M, Golkar N, Hajighahramani N, Kianpour S, Nezafat N, Ghasemi Y. Biotechnol Adv 35 575-596 (2017)
  31. Sequeira V, van der Velden J. Biophys Rev 7 421-447 (2015)
  32. Messer AE, Marston SB. Front Physiol 5 315 (2014)
  33. Debold EP, Fitts RH, Sundberg CW, Nosek TM. Med Sci Sports Exerc 48 2270-2280 (2016)
  34. Kaya Z, Katus HA, Rose NR. Clin Immunol 134 80-88 (2010)
  35. Davis J, Westfall MV, Townsend D, Blankinship M, Herron TJ, Guerrero-Serna G, Wang W, Devaney E, Metzger JM. Physiol Rev 88 1567-1651 (2008)
  36. Sun YB, Irving M. J Mol Cell Cardiol 48 859-865 (2010)
  37. Bullard B, Pastore A. J Muscle Res Cell Motil 32 303-313 (2011)
  38. Parvatiyar MS, Pinto JR, Dweck D, Potter JD. J Biomed Biotechnol 2010 350706 (2010)
  39. Debold EP. Front Physiol 6 239 (2015)
  40. Sheng JJ, Jin JP. Front Physiol 5 165 (2014)
  41. Day SM, Westfall MV, Metzger JM. J Mol Med (Berl) 85 911-921 (2007)
  42. Streng AS, de Boer D, van der Velden J, van Dieijen-Visser MP, Wodzig WK. J Mol Cell Cardiol 63 47-56 (2013)
  43. Solaro RJ. J Biomed Biotechnol 2010 105648 (2010)
  44. Ohtsuki I, Morimoto S. Biochem Biophys Res Commun 369 62-73 (2008)
  45. Capozzi F, Casadei F, Luchinat C. J Biol Inorg Chem 11 949-962 (2006)
  46. Tobacman LS. Biophys J 120 1-9 (2021)
  47. Harada K, Morimoto S. Jpn J Physiol 54 307-318 (2004)
  48. Peng Y, Ayaz-Guner S, Yu D, Ge Y. Proteomics Clin Appl 8 554-568 (2014)
  49. Murphy AM. Congest Heart Fail 12 32-8; quiz 39-40 (2006)
  50. Rahman A, Broadley SA. Emerg Med Australas 26 125-130 (2014)
  51. Cimiotti D, Budde H, Hassoun R, Jaquet K. Int J Mol Sci 22 E558 (2021)
  52. Kalyva A, Parthenakis FI, Marketou ME, Kontaraki JE, Vardas PE. J Muscle Res Cell Motil 35 161-178 (2014)
  53. Deranek AE, Klass MM, Tardiff JC. Pflugers Arch 471 661-671 (2019)
  54. Ramirez-Correa GA, Martinez-Ferrando MI, Zhang P, Murphy AM. Proteomics Clin Appl 8 543-553 (2014)
  55. Abdolrahim M, Rabiee M, Alhosseini SN, Tahriri M, Yazdanpanah S, Tayebi L. Anal Biochem 485 1-10 (2015)
  56. Sellers JR. J Muscle Res Cell Motil 25 475-482 (2004)
  57. Wakabayashi T. Proc Jpn Acad Ser B Phys Biol Sci 91 321-350 (2015)
  58. Al-Khayat HA. Glob Cardiol Sci Pract 2013 280-302 (2013)
  59. Radha R, Shahzadi SK, Al-Sayah MH. Molecules 26 4812 (2021)
  60. Eriksson S, Wittfooth S, Pettersson K. Crit Rev Clin Lab Sci 43 427-495 (2006)
  61. Tsai SH, Chu SJ, Hsu CW, Cheng SM, Yang SP. Am J Emerg Med 26 331-341 (2008)
  62. Marian AJ, Nambi V. Expert Rev Mol Diagn 4 805-820 (2004)
  63. Shimozawa T, Hirokawa E, Kobirumaki-Shimozawa F, Oyama K, Shintani SA, Terui T, Kushida Y, Tsukamoto S, Fujii T, Ishiwata S, Fukuda N. Prog Biophys Mol Biol 124 31-40 (2017)
  64. Biesiadecki BJ, Westfall MV. Arch Biochem Biophys 664 9-14 (2019)
  65. Alaiti MA, Maroo A, Edel TB. Pacing Clin Electrophysiol 32 800-810 (2009)
  66. Lynn ML, Lehman SJ, Tardiff JC. Heart Fail Clin 14 147-159 (2018)
  67. Mondal A, Jin JP. Front Physiol 7 449 (2016)
  68. Jaffe AS. Cardiol Clin 23 453-65, vi (2005)
  69. Debold EP. Exerc Sport Sci Rev 44 144-149 (2016)
  70. Turner I, Belema-Bedada F, Martindale J, Townsend D, Wang W, Palpant N, Yasuda SC, Barnabei M, Fomicheva E, Metzger JM. J Cardiovasc Transl Res 1 317-327 (2008)
  71. Papadaki M, Marston SB. Front Physiol 7 508 (2016)
  72. Rynkiewicz MJ, Pavadai E, Lehman W. Front Physiol 13 932333 (2022)
  73. Ahmed RE, Tokuyama T, Anzai T, Chanthra N, Uosaki H. Philos Trans R Soc Lond B Biol Sci 377 20210325 (2022)
  74. Anderson FL, Secombe CJ, Lester GD. Aust Vet J 91 204-208 (2013)
  75. Marston S. J Muscle Res Cell Motil 44 201-208 (2023)
  76. Lehman W, Craig R. J Muscle Res Cell Motil 25 455-466 (2004)
  77. Mariathas M, Olechowski B, Mahmoudi M, Curzen N. Expert Rev Cardiovasc Ther 16 49-57 (2018)
  78. Lu Y, Jeffries CM, Trewhella J. Biopolymers 95 505-516 (2011)
  79. van de Locht M, Borsboom TC, Winter JM, Ottenheijm CAC. Int J Mol Sci 22 9187 (2021)
  80. Martin AA, Thompson BR, Hahn D, Angulski ABB, Hosny N, Cohen H, Metzger JM. Int J Mol Sci 23 16223 (2022)
  81. England J, Loughna S, Rutland CS. J Cardiovasc Dev Dis 4 E8 (2017)
  82. Rasmi Y, Mosa OF, Alipour S, Heidari N, Javanmard F, Golchin A, Gholizadeh-Ghaleh Aziz S. Front Mol Biosci 9 821155 (2022)
  83. Bevere M, Morabito C, Mariggi貌 MA, Guarnieri S. Oxid Med Cell Longev 2022 7714542 (2022)
  84. Zonneveld MH, Abbel D, le Cessie S, Jukema JW, Noordam R, Trompet S. Aging Dis 14 386-397 (2023)
  85. Lee MMY, Masri A. Curr Heart Fail Rep (2023)
  86. Arata T. Int J Mol Sci 21 E672 (2020)
  87. Coscarella IL, Landim-Vieira M, Rastegarpouyani H, Chase PB, Irianto J, Pinto JR. Int J Mol Sci 24 13341 (2023)
  88. Ronca F, Raggi A. Mol Cell Biochem (2023)
  89. Matsuo T, Peters J. Life (Basel) 12 1259 (2022)

Articles citing this publication (319)

  1. Chen H, Zhou HX. Proteins 61 21-35 (2005)
  2. Robinson P, Griffiths PJ, Watkins H, Redwood CS. Circ Res 101 1266-1273 (2007)
  3. Sequeira V, Wijnker PJ, Nijenkamp LL, Kuster DW, Najafi A, Witjas-Paalberends ER, Regan JA, Boontje N, Ten Cate FJ, Germans T, Carrier L, Sadayappan S, van Slegtenhorst MA, Zaremba R, Foster DB, Murphy AM, Poggesi C, Dos Remedios C, Stienen GJ, Ho CY, Michels M, van der Velden J. Circ Res 112 1491-1505 (2013)
  4. Ikura M, Ames JB. Proc Natl Acad Sci U S A 103 1159-1164 (2006)
  5. Zhang J, Guy MJ, Norman HS, Chen YC, Xu Q, Dong X, Guner H, Wang S, Kohmoto T, Young KH, Moss RL, Ge Y. J Proteome Res 10 4054-4065 (2011)
  6. Gali艅ska-Rakoczy A, Engel P, Xu C, Jung H, Craig R, Tobacman LS, Lehman W. J Mol Biol 379 929-935 (2008)
  7. Pirani A, Vinogradova MV, Curmi PM, King WA, Fletterick RJ, Craig R, Tobacman LS, Xu C, Hatch V, Lehman W. J Mol Biol 357 707-717 (2006)
  8. Zhang P, Kirk JA, Ji W, dos Remedios CG, Kass DA, Van Eyk JE, Murphy AM. Circulation 126 1828-1837 (2012)
  9. Biesiadecki BJ, Kobayashi T, Walker JS, Solaro RJ, de Tombe PP. Circ Res 100 1486-1493 (2007)
  10. David A, Razali R, Wass MN, Sternberg MJ. Hum Mutat 33 359-363 (2012)
  11. Pirani A, Xu C, Hatch V, Craig R, Tobacman LS, Lehman W. J Mol Biol 346 761-772 (2005)
  12. Murakami K, Yumoto F, Ohki SY, Yasunaga T, Tanokura M, Wakabayashi T. J Mol Biol 352 178-201 (2005)
  13. Day SM, Westfall MV, Fomicheva EV, Hoyer K, Yasuda S, La Cross NC, D'Alecy LG, Ingwall JS, Metzger JM. Nat Med 12 181-189 (2006)
  14. Zabrouskov V, Ge Y, Schwartz J, Walker JW. Mol Cell Proteomics 7 1838-1849 (2008)
  15. Hershberger RE, Pinto JR, Parks SB, Kushner JD, Li D, Ludwigsen S, Cowan J, Morales A, Parvatiyar MS, Potter JD. Circ Cardiovasc Genet 2 306-313 (2009)
  16. Kampourakis T, Yan Z, Gautel M, Sun YB, Irving M. Proc Natl Acad Sci U S A 111 18763-18768 (2014)
  17. Peng Y, Gregorich ZR, Valeja SG, Zhang H, Cai W, Chen YC, Guner H, Chen AJ, Schwahn DJ, Hacker TA, Liu X, Ge Y. Mol Cell Proteomics 13 2752-2764 (2014)
  18. Sakthivel S, Finley NL, Rosevear PR, Lorenz JN, Gulick J, Kim S, VanBuren P, Martin LA, Robbins J. J Biol Chem 280 703-714 (2005)
  19. Howarth JW, Meller J, Solaro RJ, Trewhella J, Rosevear PR. J Mol Biol 373 706-722 (2007)
  20. Dong X, Sumandea CA, Chen YC, Garcia-Cazarin ML, Zhang J, Balke CW, Sumandea MP, Ge Y. J Biol Chem 287 848-857 (2012)
  21. Sun YB, Lou F, Irving M. J Physiol 587 155-163 (2009)
  22. Harada K, Potter JD. J Biol Chem 279 14488-14495 (2004)
  23. Kaya Z, G枚ser S, Buss SJ, Leuschner F, Ottl R, Li J, V枚lkers M, Zittrich S, Pfitzer G, Rose NR, Katus HA. Circulation 118 2063-2072 (2008)
  24. Jin JP, Chong SM. Arch Biochem Biophys 500 144-150 (2010)
  25. Perz-Edwards RJ, Irving TC, Baumann BA, Gore D, Hutchinson DC, Kr啪i膷 U, Porter RL, Ward AB, Reedy MK. Proc Natl Acad Sci U S A 108 120-125 (2011)
  26. Ayaz-Guner S, Zhang J, Li L, Walker JW, Ge Y. Biochemistry 48 8161-8170 (2009)
  27. Zhang Z, Biesiadecki BJ, Jin JP. Biochemistry 45 11681-11694 (2006)
  28. Carballo S, Robinson P, Otway R, Fatkin D, Jongbloed JD, de Jonge N, Blair E, van Tintelen JP, Redwood C, Watkins H. Circ Res 105 375-382 (2009)
  29. Lehman W, Gali艅ska-Rakoczy A, Hatch V, Tobacman LS, Craig R. J Mol Biol 388 673-681 (2009)
  30. Foster DB, Noguchi T, VanBuren P, Murphy AM, Van Eyk JE. Circ Res 93 917-924 (2003)
  31. Agianian B, Krzic U, Qiu F, Linke WA, Leonard K, Bullard B. EMBO J 23 772-779 (2004)
  32. Narolska NA, Piroddi N, Belus A, Boontje NM, Scellini B, Deppermann S, Zaremba R, Musters RJ, dos Remedios C, Jaquet K, Foster DB, Murphy AM, van Eyk JE, Tesi C, Poggesi C, van der Velden J, Stienen GJ. Circ Res 99 1012-1020 (2006)
  33. Davis J, Wen H, Edwards T, Metzger JM. Circ Res 100 1494-1502 (2007)
  34. Barbato JC, Huang QQ, Hossain MM, Bond M, Jin JP. J Biol Chem 280 6602-6609 (2005)
  35. Nishii K, Morimoto S, Minakami R, Miyano Y, Hashizume K, Ohta M, Zhan DY, Lu QW, Shibata Y. Dev Biol 322 65-73 (2008)
  36. Ertz-Berger BR, He H, Dowell C, Factor SM, Haim TE, Nunez S, Schwartz SD, Ingwall JS, Tardiff JC. Proc Natl Acad Sci U S A 102 18219-18224 (2005)
  37. Strahl T, Huttner IG, Lusin JD, Osawa M, King D, Thorner J, Ames JB. J Biol Chem 282 30949-30959 (2007)
  38. Grabarek Z. J Mol Biol 346 1351-1366 (2005)
  39. Wang Z, Grange M, Wagner T, Kho AL, Gautel M, Raunser S. Cell 184 2135-2150.e13 (2021)
  40. Hoffman RM, Blumenschein TM, Sykes BD. J Mol Biol 361 625-633 (2006)
  41. Hernandez OM, Szczesna-Cordary D, Knollmann BC, Miller T, Bell M, Zhao J, Sirenko SG, Diaz Z, Guzman G, Xu Y, Wang Y, Kerrick WG, Potter JD. J Biol Chem 280 37183-37194 (2005)
  42. Huang W, Zhang R, Xu X. Dev Biol 331 237-249 (2009)
  43. Gali艅ska A, Hatch V, Craig R, Murphy AM, Van Eyk JE, Wang CL, Lehman W, Foster DB. Circ Res 106 705-711 (2010)
  44. Robinson JM, Dong WJ, Xing J, Cheung HC. J Mol Biol 340 295-305 (2004)
  45. Williams MR, Lehman SJ, Tardiff JC, Schwartz SD. Proc Natl Acad Sci U S A 113 3257-3262 (2016)
  46. Lindhout DA, Litowski JR, Mercier P, Hodges RS, Sykes BD. Biopolymers 75 367-375 (2004)
  47. Robertson IM, Li MX, Sykes BD. J Biol Chem 284 23012-23023 (2009)
  48. Zhang J, Dong X, Hacker TA, Ge Y. J Am Soc Mass Spectrom 21 940-948 (2010)
  49. Guinto PJ, Haim TE, Dowell-Martino CC, Sibinga N, Tardiff JC. Am J Physiol Heart Circ Physiol 297 H614-26 (2009)
  50. Robertson IM, Sun YB, Li MX, Sykes BD. J Mol Cell Cardiol 49 1031-1041 (2010)
  51. Sumandea CA, Garcia-Cazarin ML, Bozio CH, Sievert GA, Balke CW, Sumandea MP. J Biol Chem 286 530-541 (2011)
  52. Irie T, Sips PY, Kai S, Kida K, Ikeda K, Hirai S, Moazzami K, Jiramongkolchai P, Bloch DB, Doulias PT, Armoundas AA, Kaneki M, Ischiropoulos H, Kranias E, Bloch KD, Stamler JS, Ichinose F. Circ Res 117 793-803 (2015)
  53. Dweck D, Hus N, Potter JD. J Biol Chem 283 33119-33128 (2008)
  54. Varughese JF, Chalovich JM, Li Y. J Biomol Struct Dyn 28 159-174 (2010)
  55. Wang Y, Pinto JR, Solis RS, Dweck D, Liang J, Diaz-Perez Z, Ge Y, Walker JW, Potter JD. J Biol Chem 287 2156-2167 (2012)
  56. Wang W, Barnabei MS, Asp ML, Heinis FI, Arden E, Davis J, Braunlin E, Li Q, Davis JP, Potter JD, Metzger JM. Nat Med 19 305-312 (2013)
  57. Hwang PM, Cai F, Pineda-Sanabria SE, Corson DC, Sykes BD. Proc Natl Acad Sci U S A 111 14412-14417 (2014)
  58. Yang S, Barbu-Tudoran L, Orzechowski M, Craig R, Trinick J, White H, Lehman W. Biophys J 106 855-864 (2014)
  59. Davis J, Wen H, Edwards T, Metzger JM. J Mol Cell Cardiol 44 891-904 (2008)
  60. Ramirez-Correa GA, Cortassa S, Stanley B, Gao WD, Murphy AM. J Mol Cell Cardiol 48 943-953 (2010)
  61. Wang D, Robertson IM, Li MX, McCully ME, Crane ML, Luo Z, Tu AY, Daggett V, Sykes BD, Regnier M. Biochemistry 51 4473-4487 (2012)
  62. Biesiadecki BJ, Chong SM, Nosek TM, Jin JP. Biochemistry 46 1368-1379 (2007)
  63. Zhang X, Kampourakis T, Yan Z, Sevrieva I, Irving M, Sun YB. Elife 6 e24081 (2017)
  64. Boussouf SE, Maytum R, Jaquet K, Geeves MA. J Muscle Res Cell Motil 28 49-58 (2007)
  65. Sandaradura SA, Bournazos A, Mallawaarachchi A, Cummings BB, Waddell LB, Jones KJ, Troedson C, Sudarsanam A, Nash BM, Peters GB, Algar EM, MacArthur DG, North KN, Brammah S, Charlton A, Laing NG, Wilson MJ, Davis MR, Cooper ST. Hum Mutat 39 383-388 (2018)
  66. Wang X, Huang QQ, Breckenridge MT, Chen A, Crawford TO, Morton DH, Jin JP. J Biol Chem 280 13241-13249 (2005)
  67. Liou YM, Kuo SC, Hsieh SR. Pflugers Arch 456 787-800 (2008)
  68. Debold EP. Front Physiol 3 151 (2012)
  69. Dvornikov AV, Smolin N, Zhang M, Martin JL, Robia SL, de Tombe PP. J Biol Chem 291 21817-21828 (2016)
  70. Westfall MV, Metzger JM. J Mol Cell Cardiol 43 107-118 (2007)
  71. Gafurov B, Fredricksen S, Cai A, Brenner B, Chase PB, Chalovich JM. Biochemistry 43 15276-15285 (2004)
  72. Cheng Y, Rao V, Tu AY, Lindert S, Wang D, Oxenford L, McCulloch AD, McCammon JA, Regnier M. J Biol Chem 290 27749-27766 (2015)
  73. Glaaser IW, Bankston JR, Liu H, Tateyama M, Kass RS. J Biol Chem 281 24015-24023 (2006)
  74. Nongthomba U, Ansari M, Thimmaiya D, Stark M, Sparrow J. Genetics 177 295-306 (2007)
  75. Manning EP, Guinto PJ, Tardiff JC. J Biol Chem 287 14515-14523 (2012)
  76. Meng F, Kurgan L. Bioinformatics 32 i341-i350 (2016)
  77. Cammarato A, Hatch V, Saide J, Craig R, Sparrow JC, Tobacman LS, Lehman W. Biophys J 86 1618-1624 (2004)
  78. Martins AS, Parvatiyar MS, Feng HZ, Bos JM, Gonzalez-Martinez D, Vukmirovic M, Turna RS, Sanchez-Gonzalez MA, Badger CD, Zorio DAR, Singh RK, Wang Y, Jin JP, Ackerman MJ, Pinto JR. Circ Cardiovasc Genet 8 653-664 (2015)
  79. Schoffstall B, Brunet NM, Williams S, Miller VF, Barnes AT, Wang F, Compton LA, McFadden LA, Taylor DW, Seavy M, Dhanarajan R, Chase PB. J Physiol 577 935-944 (2006)
  80. You B, Yan G, Zhang Z, Yan L, Li J, Ge Q, Jin JP, Sun J. Biochem J 418 93-101 (2009)
  81. Sun YB, Brandmeier B, Irving M. Proc Natl Acad Sci U S A 103 17771-17776 (2006)
  82. Franklin AJ, Baxley T, Kobayashi T, Chalovich JM. Biophys J 102 2536-2544 (2012)
  83. Mudalige WA, Tao TC, Lehrer SS. J Mol Biol 389 575-583 (2009)
  84. Shastri AT, Samarasekara S, Muniraman H, Clarke P. Acta Paediatr 101 26-29 (2012)
  85. Debold EP. Med Sci Sports Exerc 44 1440-1452 (2012)
  86. Biesiadecki BJ, Schneider KL, Yu ZB, Chong SM, Jin JP. J Biol Chem 279 13825-13832 (2004)
  87. Holthauzen LM, Corr锚a F, Farah CS. J Biol Chem 279 15204-15213 (2004)
  88. Westfall MV, Lee AM, Robinson DA. J Biol Chem 280 41324-41331 (2005)
  89. Mannick EE, Bonomolo JC, Horswell R, Lentz JJ, Serrano MS, Zapata-Velandia A, Gastanaduy M, Himel JL, Rose SL, Udall JN, Hornick CA, Liu Z. Clin Immunol 112 247-257 (2004)
  90. Zhou Z, Li KL, Rieck D, Ouyang Y, Chandra M, Dong WJ. J Biol Chem 287 7661-7674 (2012)
  91. Paul DM, Morris EP, Kensler RW, Squire JM, Squire JM. J Biol Chem 284 15007-15015 (2009)
  92. Pineda-Sanabria SE, Robertson IM, Sykes BD. Biochemistry 50 1309-1320 (2011)
  93. Nadeau OW, Anderson DW, Yang Q, Artigues A, Paschall JE, Wyckoff GJ, McClintock JL, Carlson GM. J Mol Biol 365 1429-1445 (2007)
  94. Swindle N, Tikunova SB. Biochemistry 49 4813-4820 (2010)
  95. Engel PL, Kobayashi T, Biesiadecki B, Davis J, Tikunova S, Wu S, Solaro RJ. J Biol Chem 282 183-193 (2007)
  96. Solzin J, Iorga B, Sierakowski E, Gomez Alcazar DP, Ruess DF, Kubacki T, Zittrich S, Blaudeck N, Pfitzer G, Stehle R. Biophys J 93 3917-3931 (2007)
  97. Zhang J, Zhang H, Ayaz-Guner S, Chen YC, Dong X, Xu Q, Ge Y. Biochemistry 50 6081-6092 (2011)
  98. Papadaki M, Vikhorev PG, Marston SB, Messer AE. Cardiovasc Res 108 99-110 (2015)
  99. McConnell M, Tal Grinspan L, Williams MR, Lynn ML, Schwartz BA, Fass OZ, Schwartz SD, Tardiff JC. Biochemistry 56 3403-3413 (2017)
  100. Vassylyev DG, Symersky J. J Mol Biol 370 417-426 (2007)
  101. Dweck D, Reynaldo DP, Pinto JR, Potter JD. J Biol Chem 285 17371-17379 (2010)
  102. Sancho Solis R, Ge Y, Walker JW. Protein Sci 20 894-907 (2011)
  103. Blumenschein TM, Stone DB, Fletterick RJ, Mendelson RA, Sykes BD. J Biol Chem 280 21924-21932 (2005)
  104. Lu X, Tobacman LS, Kawai M. J Physiol 553 457-471 (2003)
  105. Iwamoto H. J Mol Biol 390 99-111 (2009)
  106. Eichm眉ller C, Skrynnikov NR. J Biomol NMR 37 79-95 (2007)
  107. Sadayappan S, Finley N, Howarth JW, Osinska H, Klevitsky R, Lorenz JN, Rosevear PR, Robbins J. FASEB J 22 1246-1257 (2008)
  108. Gong H, Hatch V, Ali L, Lehman W, Craig R, Tobacman LS. Proc Natl Acad Sci U S A 102 656-661 (2005)
  109. Norman C, Rall JA, Tikunova SB, Davis JP. Am J Physiol Heart Circ Physiol 293 H2580-7 (2007)
  110. King WA, Stone DB, Timmins PA, Narayanan T, von Brasch AA, Mendelson RA, Curmi PM. J Mol Biol 345 797-815 (2005)
  111. Mathur MC, Kobayashi T, Chalovich JM. Biophys J 96 2237-2244 (2009)
  112. Xing J, Chinnaraj M, Zhang Z, Cheung HC, Dong WJ. Biochemistry 47 13383-13393 (2008)
  113. Vikhorev PG, Song W, Wilkinson R, Copeland O, Messer AE, Ferenczi MA, Marston SB. Biophys J 107 2369-2380 (2014)
  114. Gollapudi SK, Gallon CE, Chandra M. J Mol Biol 425 1565-1581 (2013)
  115. Kowlessur D, Tobacman LS. J Biol Chem 285 2686-2694 (2010)
  116. Bell MG, Lankford EB, Gonye GE, Ellis-Davies GC, Martyn DA, Regnier M, Barsotti RJ. Biophys J 90 531-543 (2006)
  117. Houmeida A, Heeley DH, Belknap B, White HD. J Biol Chem 285 32760-32769 (2010)
  118. Wei B, Gao J, Huang XP, Jin JP. J Biol Chem 285 27806-27816 (2010)
  119. Chaudhuri T, Mukherjea M, Sachdev S, Randall JD, Sarkar S. J Mol Biol 352 58-71 (2005)
  120. Gonzalez-Martinez D, Johnston JR, Landim-Vieira M, Ma W, Antipova O, Awan O, Irving TC, Bryant Chase P, Pinto JR. J Mol Cell Cardiol 123 26-37 (2018)
  121. Fusi L, Brunello E, Sevrieva IR, Sun YB, Irving M. Proc Natl Acad Sci U S A 111 4626-4631 (2014)
  122. Ruksana R, Kuroda K, Terami H, Bando T, Kitaoka S, Takaya T, Sakube Y, Kagawa H. Genes Cells 10 261-276 (2005)
  123. Knowles AC, Irving M, Sun YB. J Mol Biol 421 125-137 (2012)
  124. Matsumoto F, Makino K, Maeda K, Patzelt H, Ma茅da Y, Fujiwara S. J Mol Biol 342 1209-1221 (2004)
  125. Warren CM, Karam CN, Wolska BM, Kobayashi T, de Tombe PP, Arteaga GM, Bos JM, Ackerman MJ, Solaro RJ. Circ Cardiovasc Genet 8 765-773 (2015)
  126. Finley NL, Rosevear PR. J Biol Chem 279 54833-54840 (2004)
  127. article-commentary Marian AJ. Circulation 111 2276-2279 (2005)
  128. News Sykes BD. Nat Struct Biol 10 588-589 (2003)
  129. Paul DM, Squire JM, Morris EP. J Struct Biol 197 365-371 (2017)
  130. Warren CM, Kobayashi T, Solaro RJ. J Biol Chem 284 14258-14266 (2009)
  131. Matsuo T, Yagi N. J Mol Biol 383 1019-1036 (2008)
  132. Casas-Tint贸 S, Maraver A, Serrano M, Ferr煤s A. Oncotarget 7 52631-52642 (2016)
  133. Robertson IM, Baryshnikova OK, Li MX, Sykes BD. Biochemistry 47 7485-7495 (2008)
  134. Tamura T, Wakayama J, Inoue K, Yagi N, Iwamoto H. Biophys J 96 1045-1055 (2009)
  135. Kimura-Sakiyama C, Ueno Y, Wakabayashi K, Miki M. J Mol Biol 376 80-91 (2008)
  136. Xiao H, Langerman A, Zhang Y, Khalid O, Hu S, Cao CX, Lingen MW, Wong DTW. Oral Oncol 51 1011-1019 (2015)
  137. Varughese JF, Baxley T, Chalovich JM, Li Y. J Phys Chem B 115 2392-2400 (2011)
  138. Kobayashi T, Patrick SE, Kobayashi M. J Biol Chem 284 20052-20060 (2009)
  139. Moreno-Gonzalez A, Fredlund J, Regnier M. J Physiol 562 873-884 (2005)
  140. Kwon YC, Kim MG, Kim EM, Shin YB, Lee SK, Lee SD, Cho MJ, Ro HS. Biotechnol Lett 33 921-927 (2011)
  141. Burkeen AK, Maday SL, Rybicka KK, Sulcove JA, Ward J, Huang MM, Barstead R, Franzini-Armstrong C, Allen TS. Biophys J 86 991-1001 (2004)
  142. Pavadai E, Rynkiewicz MJ, Ghosh A, Lehman W. Biophys J 118 325-336 (2020)
  143. Melnikov EE, Andrianova AG, Morozkin AD, Stepnov AA, Makhovskaya OV, Botos I, Gustchina A, Wlodawer A, Rotanova TV. Acta Biochim Pol 55 281-296 (2008)
  144. Piroddi N, Witjas-Paalberends ER, Ferrara C, Ferrantini C, Vitale G, Scellini B, Wijnker PJM, Sequiera V, Dooijes D, Dos Remedios C, Schlossarek S, Leung MC, Messer A, Ward DG, Biggeri A, Tesi C, Carrier L, Redwood CS, Marston SB, van der Velden J, Poggesi C. J Gen Physiol 151 18-29 (2019)
  145. Veltri T, de Oliveira GAP, Bienkiewicz EA, Palhano FL, Marques MA, Moraes AH, Silva JL, Sorenson MM, Pinto JR. Sci Rep 7 691 (2017)
  146. Zhang Z, Akhter S, Mottl S, Jin JP. FEBS J 278 3348-3359 (2011)
  147. Alderman SL, Klaiman JM, Deck CA, Gillis TE. Am J Physiol Regul Integr Comp Physiol 303 R168-76 (2012)
  148. Zot HG, Hasbun JE, Michell CA, Landim-Vieira M, Pinto JR. Arch Biochem Biophys 601 97-104 (2016)
  149. Moore RK, Grinspan LT, Jimenez J, Guinto PJ, Ertz-Berger B, Tardiff JC. J Mol Cell Cardiol 58 188-198 (2013)
  150. Swartz DR, Yang Z, Sen A, Tikunova SB, Davis JP. J Mol Biol 361 420-435 (2006)
  151. Nakamura M, Ueki S, Hara H, Arata T. J Mol Biol 348 127-137 (2005)
  152. Gollapudi SK, Chandra M. Biochem Res Int 2012 824068 (2012)
  153. Greenberg MJ, Tardiff JC. J Gen Physiol 153 e202012662 (2021)
  154. Lapek JD, Mills RH, Wozniak JM, Campeau A, Fang RH, Wei X, van de Groep K, Perez-Lopez A, van Sorge NM, Raffatellu M, Knight R, Zhang L, Gonzalez DJ. Cell Syst 6 579-592.e4 (2018)
  155. Michael JJ, Gollapudi SK, Chandra M. Basic Res Cardiol 109 442 (2014)
  156. Zhao C, Trudeau B, Xie H, Prostko J, Fishpaugh J, Ramsay C. Proteomics 14 1311-1321 (2014)
  157. Veltri T, Landim-Vieira M, Parvatiyar MS, Gonzalez-Martinez D, Dieseldorff Jones KM, Michell CA, Dweck D, Landstrom AP, Chase PB, Pinto JR. Front Physiol 8 221 (2017)
  158. Lymperopoulos A, Garcia D, Walklett K. Pharmacogenomics 15 1807-1821 (2014)
  159. Kowlessur D, Tobacman LS. J Biol Chem 287 42299-42311 (2012)
  160. Hoffman RM, Sykes BD. Biochemistry 48 5541-5552 (2009)
  161. Lu X, Tobacman LS, Kawai M. Biophys J 91 4230-4240 (2006)
  162. Aihara T, Ueki S, Nakamura M, Arata T. Biochem Biophys Res Commun 340 462-468 (2006)
  163. Guinto PJ, Manning EP, Schwartz SD, Tardiff JC. J Theor Comput Chem 6 413 (2007)
  164. Matsumoto F, Maeda K, Chatake T, Ma茅da Y, Fujiwara S. Biochem Biophys Res Commun 382 205-209 (2009)
  165. Uitterdijk A, Sneep S, van Duin RW, Krabbendam-Peters I, Gorsse-Bakker C, Duncker DJ, van der Giessen WJ, van Beusekom HM. Am J Physiol Heart Circ Physiol 305 H1104-10 (2013)
  166. Palpant NJ, Day SM, Herron TJ, Converso KL, Metzger JM. Cardiovasc Res 80 209-218 (2008)
  167. Herranz R, Mateos J, Mas JA, Garc铆a-Zaragoza E, Cervera M, Marco R. Mol Biol Evol 22 2231-2242 (2005)
  168. Pinto JR, Gomes AV, Jones MA, Liang J, Nguyen S, Miller T, Parvatiyar MS, Potter JD. J Biol Chem 287 37362-37370 (2012)
  169. Reinoso TR, Landim-Vieira M, Shi Y, Johnston JR, Chase PB, Parvatiyar MS, Landstrom AP, Pinto JR, Tadros HJ. J Muscle Res Cell Motil 42 323-342 (2021)
  170. Larsson L, Wang X, Yu F, H枚枚k P, Borg K, Chong SM, Jin JP. Am J Physiol Cell Physiol 295 C722-31 (2008)
  171. Lang SE, Schwank J, Stevenson TK, Jensen MA, Westfall MV. J Mol Cell Cardiol 79 264-274 (2015)
  172. Julien O, Mercier P, Allen CN, Fisette O, Ramos CH, Lag眉e P, Blumenschein TM, Sykes BD. Proteins 79 1240-1250 (2011)
  173. Varguhese JF, Li Y. J Biomol Struct Dyn 29 123-135 (2011)
  174. Palpant NJ, D'Alecy LG, Metzger JM. FASEB J 23 1529-1540 (2009)
  175. Jeyasingham MD, Artigues A, Nadeau OW, Carlson GM. J Mol Biol 377 623-629 (2008)
  176. Aihara T, Nakamura M, Ueki S, Hara H, Miki M, Arata T. J Biol Chem 285 10671-10677 (2010)
  177. Tassieri M, Evans RM, Barbu-Tudoran L, Trinick J, Waigh TA. Biophys J 94 2170-2178 (2008)
  178. De Nicola G, Burkart C, Qiu F, Agianian B, Labeit S, Martin S, Bullard B, Pastore A. Structure 15 813-824 (2007)
  179. Zamora JE, Papadaki M, Messer AE, Marston SB, Gould IR. Phys Chem Chem Phys 18 20691-20707 (2016)
  180. Moore RK, Abdullah S, Tardiff JC. Arch Biochem Biophys 552-553 21-28 (2014)
  181. Tanaka H, Takeya Y, Doi T, Yumoto F, Tanokura M, Ohtsuki I, Nishita K, Ojima T. FEBS J 272 4475-4486 (2005)
  182. Cheng Y, Lindert S, Oxenford L, Tu AY, McCulloch AD, Regnier M. J Phys Chem B 120 8238-8253 (2016)
  183. Pinto JR, Yang SW, Hitz MP, Parvatiyar MS, Jones MA, Liang J, Kokta V, Talajic M, Tremblay N, Jaeggi M, Andelfinger G, Potter JD. J Biol Chem 286 20901-20912 (2011)
  184. Kekenes-Huskey PM, Gillette A, Hake J, McCammon JA. Comput Sci Discov 5 014015 (2012)
  185. Huang RY, Rempel DL, Gross ML. Biochemistry 50 5426-5435 (2011)
  186. Cordina NM, Liew CK, Gell DA, Fajer PG, Mackay JP, Brown LJ. Protein Sci 21 1376-1387 (2012)
  187. Sheehan A, Messer AE, Papadaki M, Choudhry A, Kren V, Biedermann D, Blagg B, Khandelwal A, Marston SB. Front Physiol 9 243 (2018)
  188. Barnes DE, Hwang H, Ono K, Lu H, Ono S. Cytoskeleton (Hoboken) 73 117-130 (2016)
  189. Jain R, Kumar S, Gourinath S, Bhattacharya S, Bhattacharya A. PLoS One 4 e5269 (2009)
  190. Wijnker PJ, Sequeira V, Witjas-Paalberends ER, Foster DB, dos Remedios CG, Murphy AM, Stienen GJ, van der Velden J. Arch Biochem Biophys 554 11-21 (2014)
  191. Akhter S, Bueltmann K, Huang X, Jin JP. Arch Biochem Biophys 552-553 3-10 (2014)
  192. Sugimoto Y, Takezawa Y, Matsuo T, Ueno Y, Minakata S, Tanaka H, Wakabayashi K. Biochem Biophys Res Commun 369 100-108 (2008)
  193. Longyear T, Walcott S, Debold EP. Sci Rep 7 1822 (2017)
  194. Robertson IM, Sevrieva I, Li MX, Irving M, Sun YB, Sykes BD. J Mol Cell Cardiol 87 257-269 (2015)
  195. Maytum R, Bathe F, Konrad M, Geeves MA. J Biol Chem 279 18203-18209 (2004)
  196. Ly T, Pappas CT, Johnson D, Schlecht W, Colpan M, Galkin VE, Gregorio CC, Dong WJ, Kostyukova AS. Mol Biol Cell 30 268-281 (2019)
  197. Landim-Vieira M, Johnston JR, Ji W, Mis EK, Tijerino J, Spencer-Manzon M, Jeffries L, Hall EK, Panisello-Manterola D, Khokha MK, Deniz E, Chase PB, Lakhani SA, Pinto JR. Front Physiol 10 1612 (2019)
  198. Wang C, Wu M, Qian J, Li B, Tu X, Xu C, Li S, Chen S, Zhao Y, Huang Y, Shi L, Cheng X, Liao Y, Chen Q, Xia Y, Yao W, Wu G, Cheng M, Wang QK. Mol Genet Genomics 291 79-92 (2016)
  199. Pavadai E, Rynkiewicz MJ, Yang Z, Gould IR, Marston SB, Lehman W. Arch Biochem Biophys 725 109282 (2022)
  200. Lang SE, Robinson DA, Wu HC, Herron TJ, Wahr PA, Westfall MV. Arch Biochem Biophys 535 49-55 (2013)
  201. Henze M, Patrick SE, Hinken A, Scruggs SB, Goldspink P, de Tombe PP, Kobayashi M, Ping P, Kobayashi T, Solaro RJ. Biochim Biophys Acta 1833 823-832 (2013)
  202. Ouyang Y, Mamidi R, Jayasundar JJ, Chandra M, Dong WJ. J Mol Biol 400 1036-1045 (2010)
  203. Gilda JE, Xu Q, Martinez ME, Nguyen ST, Chase PB, Gomes AV. Arch Biochem Biophys 601 88-96 (2016)
  204. Guy MJ, Chen YC, Clinton L, Zhang H, Zhang J, Dong X, Xu Q, Ayaz-Guner S, Ge Y. Clin Chim Acta 420 82-88 (2013)
  205. Shitaka Y, Kimura C, Miki M. J Biol Chem 280 2613-2619 (2005)
  206. Robertson IM, Boyko RF, Sykes BD. J Biomol NMR 51 115-122 (2011)
  207. Terse PS, Joshi PS, Bordelon NR, Brys AM, Patton KM, Arndt TP, Sutula TP. Int J Toxicol 35 284-293 (2016)
  208. Tsaloglou MN, Jacobs A, Morgan H. Anal Bioanal Chem 406 5967-5976 (2014)
  209. Miki M, Makimura S, Saitoh T, Bunya M, Sugahara Y, Ueno Y, Kimura-Sakiyama C, Tobita H. J Mol Biol 414 765-782 (2011)
  210. Miki M, Makimura S, Sugahara Y, Yamada R, Bunya M, Saitoh T, Tobita H. J Mol Biol 420 40-55 (2012)
  211. Jung HS, Craig R. J Mol Biol 383 512-519 (2008)
  212. Preston LC, Ashley CC, Redwood CS. Biochem Biophys Res Commun 360 27-32 (2007)
  213. Coldren WH, Tikunova SB, Davis JP, Lindert S. J Chem Inf Model 60 3648-3661 (2020)
  214. Kozaili JM, Leek D, Tobacman LS. J Biol Chem 285 38034-38041 (2010)
  215. Gunther LK, Feng HZ, Wei H, Raupp J, Jin JP, Sakamoto T. Biochemistry 55 1887-1897 (2016)
  216. De Santis E, Faruqui N, Noble JE, Ryadnov MG. Nanoscale 6 11425-11430 (2014)
  217. Abdullah S, Lynn ML, McConnell MT, Klass MM, Baldo AP, Schwartz SD, Tardiff JC. J Biol Chem 294 14634-14647 (2019)
  218. Hoffman RM, Sykes BD. Proteins 73 338-350 (2008)
  219. Pinto JR, Veltri T, Sorenson MM. Pflugers Arch 456 1177-1187 (2008)
  220. Cenci L, Anesi A, Busato M, Guella G, Bossi AM. J Mol Recognit 29 41-50 (2016)
  221. Schwan J, Campbell SG. Biomark Insights 10 91-103 (2015)
  222. Tikunova SB, Cuesta A, Price M, Li MX, Belevych N, Biesiadecki BJ, Reiser PJ, Hwang PM, Davis JP. J Gen Physiol 151 9-17 (2019)
  223. Paul DM, Squire JM, Squire JM, Morris EP. J Struct Biol 170 278-285 (2010)
  224. Comment Murphy AM. Circ Res 95 1043-1045 (2004)
  225. Johnson D, Zhu L, Landim-Vieira M, Pinto JR, Chalovich JM. J Biol Chem 294 19535-19545 (2019)
  226. Cordina NM, Liew CK, Potluri PR, Curmi PM, Fajer PG, Logan TM, Mackay JP, Brown LJ. PLoS One 9 e112976 (2014)
  227. Kobayashi M, Debold EP, Turner MA, Kobayashi T. J Biol Chem 288 26335-26349 (2013)
  228. Lassalle MW. Biosci Biotechnol Biochem 74 82-91 (2010)
  229. Gallon CE, Tschirgi ML, Chandra M. Arch Biochem Biophys 456 127-134 (2006)
  230. Meyer NL, Chase PB. Arch Biochem Biophys 601 80-87 (2016)
  231. Vetter AD, Martin AA, Thompson BR, Thomas DD, Metzger JM. J Mol Cell Cardiol 147 49-61 (2020)
  232. Akhter S, Zhang Z, Jin JP. Am J Physiol Heart Circ Physiol 302 H923-33 (2012)
  233. Botten D, Fugallo G, Fraternali F, Molteni C. PLoS One 8 e70556 (2013)
  234. Bai F, Caster HM, Pinto JR, Kawai M. Biophys J 104 1979-1988 (2013)
  235. Longyear TJ, Turner MA, Davis JP, Lopez J, Biesiadecki B, Debold EP. J Appl Physiol (1985) 116 1165-1174 (2014)
  236. Sol铆s C, Kim GH, Moutsoglou ME, Robinson JM. Biophys J 115 1762-1769 (2018)
  237. Ramirez-Correa GA, Frazier AH, Zhu G, Zhang P, Rappold T, Kooij V, Bedja D, Snyder GA, Lugo-Fagundo NS, Hariharan R, Li Y, Shen X, Gao WD, Cingolani OH, Takimoto E, Foster DB, Murphy AM. J Appl Physiol (1985) 118 212-223 (2015)
  238. Gaffin RD, Tong CW, Zawieja DC, Hewett TE, Klevitsky R, Robbins J, Muthuchamy M. J Physiol 561 777-791 (2004)
  239. Chen YC, Sumandea MP, Larsson L, Moss RL, Ge Y. J Muscle Res Cell Motil 36 169-181 (2015)
  240. Akhter S, Jin JP. FEBS Open Bio 5 64-75 (2015)
  241. Schlecht W, Zhou Z, Li KL, Rieck D, Ouyang Y, Dong WJ. Arch Biochem Biophys 550-551 1-11 (2014)
  242. Lang SE, Stevenson TK, Schatz TM, Biesiadecki BJ, Westfall MV. Arch Biochem Biophys 627 1-9 (2017)
  243. Pineda-Sanabria SE, Robertson IM, Li MX, Sykes BD. Cardiovasc Res 97 481-489 (2013)
  244. Kowlessur D, Tobacman LS. J Biol Chem 285 38978-38986 (2010)
  245. Kalyanaraman M, Bhalala U, Leoncio M. Pediatr Emerg Care 27 933-936 (2011)
  246. Wei H, Jin JP. Am J Physiol Cell Physiol 307 C338-48 (2014)
  247. Martin SR, Avella G, Adrover M, de Nicola GF, Bullard B, Pastore A. Biochemistry 50 1839-1847 (2011)
  248. Li JL, Geng CY, Bu Y, Huang XR, Sun CC. J Comput Chem 30 1135-1145 (2009)
  249. Gafurov B, Chalovich JM. FEBS J 274 2287-2299 (2007)
  250. Doi T, Satoh A, Tanaka H, Inoue A, Yumoto F, Tanokura M, Ohtsuki I, Nishita K, Ojima T. Arch Biochem Biophys 436 83-90 (2005)
  251. Mukhopadhyay S, Langsetmo K, Stafford WF, Henry GD, Baleja JD, Sarkar S. J Biol Chem 280 538-547 (2005)
  252. Tiroli AO, Tasic L, Oliveira CL, Bloch C, Torriani I, Farah CS, Ramos CH. FEBS J 272 779-790 (2005)
  253. Fujiwara S, Matsumoto F. J Mol Biol 367 16-24 (2007)
  254. Johnson D, Angus CW, Chalovich JM. Biophys J 115 702-712 (2018)
  255. Yaguchi S, Yaguchi J, Tanaka H. Sci Rep 7 43563 (2017)
  256. Cool AM, Lindert S. J Chem Inf Model 62 5666-5674 (2022)
  257. Tanaka H, Takahashi H, Ojima T. FEBS Lett 587 2612-2616 (2013)
  258. Patel DA, Root DD. Biochemistry 48 357-369 (2009)
  259. Robertson IM, Pineda-Sanabria SE, Holmes PC, Sykes BD. Arch Biochem Biophys 552-553 40-49 (2014)
  260. article-commentary Vanburen P, Palmer BM. Circulation 121 351-353 (2010)
  261. Li AY, Lee J, Borek D, Otwinowski Z, Tibbits GF, Paetzel M. J Mol Biol 413 699-711 (2011)
  262. Yang Y, Bartz TM, Brown MR, Guo X, Zilh茫o NR, Trompet S, Weiss S, Yao J, Brody JA, Defilippi CR, Hoogeveen RC, Lin HJ, Gudnason V, Ballantyne CM, D枚rr M, Jukema JW, Petersmann A, Psaty BM, Rotter JI, Boerwinkle E, Fornage M, Jun G, Yu B. Circ Genom Precis Med 14 e003460 (2021)
  263. Michael JJ, Chandra M. J Am Heart Assoc 5 e002777 (2016)
  264. Dieseldorff Jones KM, Koh Y, Weller RS, Turna RS, Ahmad F, Huke S, Knollmann BC, Pinto JR, Hwang HS. Arch Biochem Biophys 661 125-131 (2019)
  265. Li MX, Gelozia S, Danmaliki GI, Wen Y, Liu PB, Lemieux MJ, West FG, Sykes BD, Hwang PM. Biochem Biophys Rep 16 145-151 (2018)
  266. Barrick SK, Greenberg L, Greenberg MJ. Mol Biol Cell 32 1677-1689 (2021)
  267. Coffee Castro-Zena PG, Root DD. Arch Biochem Biophys 535 14-21 (2013)
  268. Gao J, Luo J, Fan R, Guan G, Fingerle V, Sugimoto C, Inoue N, Yin H. Comp Biochem Physiol B Biochem Mol Biol 151 323-329 (2008)
  269. Hassoun R, Budde H, Mannherz HG, L贸di M, Fujita-Becker S, Laser KT, G盲rtner A, Klingel K, M枚hner D, Stehle R, Sultana I, Schaaf T, Majchrzak M, Krause V, Herrmann C, Nowaczyk MM, M眉gge A, Pfitzer G, Schr枚der RR, Hamdani N, Milting H, Jaquet K, Cimiotti D. Int J Mol Sci 22 9625 (2021)
  270. 膶uli膰 V, Miyake N, Jankovi膰 S, Petrovi膰 D, 艩imunovi膰 M, 膼api膰 T, Shiina M, Ogata K, Matsumoto N. Hum Genome Var 3 16035 (2016)
  271. Dennisson JG, Tando Y, Sato N, Ogasawara M, Kubokawa K, Obinata T. Zoolog Sci 27 461-469 (2010)
  272. Boutilier JK, Taylor RL, Mann T, McNamara E, Hoffman GJ, Kenny J, Dilley RJ, Henry P, Morahan G, Laing NG, Nowak KJ. G3 (Bethesda) 7 2999-3017 (2017)
  273. Margaret Sunitha S, Mercer JA, Spudich JA, Sowdhamini R. Bioinform Biol Insights 6 203-223 (2012)
  274. Michael JJ, Gollapudi SK, Chandra M. J Muscle Res Cell Motil 37 83-93 (2016)
  275. Lopez-Davila AJ, Elhamine F, Ruess DF, Papadopoulos S, Iorga B, Kulozik FP, Zittrich S, Solzin J, Pfitzer G, Stehle R. Biophys J 103 1254-1264 (2012)
  276. Lin YH, Yap J, Ramachandra CJA, Hausenloy DJ. Cond Med 2 213-224 (2019)
  277. Khodadadian A, Hosseini K, Manzour-Ol-Ajdad A, Hedayati M, Kalantarinejad R, Heitzinger C. Comput Biol Med 87 46-56 (2017)
  278. Deranek AE, Baldo AP, Lynn ML, Schwartz SD, Tardiff JC. Biochemistry 61 1229-1242 (2022)
  279. Hornos F, Feng HZ, Rizzuti B, Palomino-Sch盲tzlein M, Wieczorek D, Neira JL, Jin JP. J Biol Chem 296 100228 (2021)
  280. Sanfelice D, Sanz-Hern谩ndez M, de Simone A, Bullard B, Pastore A. J Biol Chem 291 16090-16099 (2016)
  281. Letter Hwang PM. Cardiovasc Res 109 185-186 (2016)
  282. Case Reports Gerhardt T, Monserrat L, Landmesser U, Poller W. Eur Heart J Case Rep 6 ytac053 (2022)
  283. Sol铆s C, Robinson JM. FEBS Open Bio 10 1362-1372 (2020)
  284. Bou-Assaf GM, Chamoun JE, Emmett MR, Fajer PG, Marshall AG. Int J Mass Spectrom 302 116-124 (2011)
  285. L贸pez-D谩vila AJ, Chalovich JM, Zittrich S, Piep B, Matinmehr F, M谩ln谩si-Csizmadia A, Rauscher A脕, Kraft T, Brenner B, Stehle R. Front Physiol 11 144 (2020)
  286. Cammarato A, Craig R, Lehman W. Biochem Biophys Res Commun 391 193-197 (2010)
  287. Gautam PL, Luthra N, Kaur M, Singh J, Wander GS, Tandon R, Namrata, Gautam N. J Clin Diagn Res 11 OC33-OC36 (2017)
  288. Lang SE, Stevenson TK, Xu D, O'Connell R, Westfall MV. Arch Biochem Biophys 601 42-47 (2016)
  289. Shi Y, Bethea JP, Hetzel-Ebben HL, Landim-Vieira M, Mayper RJ, Williams RL, Kessler LE, Ruiz AM, Gargiulo K, Rose JSM, Platt G, Pinto JR, Washburn BK, Chase PB. J Muscle Res Cell Motil 42 399-417 (2021)
  290. Jackson CE, Dalzell JR, Gardner RS. Biomark Med 3 483-493 (2009)
  291. Comment Sykes BD. Structure 15 753-754 (2007)
  292. Mahmud Z, Tikunova S, Belevych N, Wagg CS, Zhabyeyev P, Liu PB, Rasicci DV, Yengo CM, Oudit GY, Lopaschuk GD, Reiser PJ, Davis JP, Hwang PM. Front Physiol 13 892979 (2022)
  293. Hantz ER, Tikunova SB, Belevych N, Davis JP, Reiser PJ, Lindert S. J Chem Inf Model 63 3462-3473 (2023)
  294. Julien O, Mercier P, Crane ML, Sykes BD. Protein Sci 18 1165-1174 (2009)
  295. Chandra D, Sankalia N, Arcibal I, Banta S, Cropek D, Karande P. Biopolymers 102 97-106 (2014)
  296. Fujiwara S. Medicina (Kaunas) 58 795 (2022)
  297. Systematic Review Chalovich JM, Zhu L, Johnson D. Front Physiol 13 902079 (2022)
  298. R枚wer C, Ortmann C, Neamtu A, El-Kased RF, Glocker MO. Biomolecules 13 187 (2023)
  299. Gergely J. Biochem Biophys Res Commun 369 49-51 (2008)
  300. Zot HG, Hasbun JE. Front Physiol 7 406 (2016)
  301. Matsumoto F, Deshimaru S, Oda T, Fujiwara S. Anal Biochem 399 299-301 (2010)
  302. Zhao C, Somiya T, Takai S, Ueki S, Arata T. Sci Rep 9 15259 (2019)
  303. Rayani K, Hantz ER, Haji-Ghassemi O, Li AY, Spuches AM, Van Petegem F, Solaro RJ, Lindert S, Tibbits GF. FEBS J 289 7446-7465 (2022)
  304. Cai F, Kampourakis T, Klein BA, Sykes BD. ACS Med Chem Lett 12 1503-1507 (2021)
  305. Sears EJ, Gillis TE. Comp Biochem Physiol B Biochem Mol Biol 202 8-15 (2016)
  306. Novello MJ, Zhang M, Snyder HE, Lin QT. J Physiol 597 1227-1229 (2019)
  307. Cai F, Kampourakis T, Parijat P, Cockburn KT, Sykes BD. ACS Med Chem Lett 14 530-533 (2023)
  308. Thompson BR, Soller KJ, Vetter A, Yang J, Veglia G, Bowser MT, Metzger JM. J Mol Cell Cardiol 130 1-9 (2019)
  309. Cao T, Akhter S, Jin JP. J Mol Evol 90 452-467 (2022)
  310. Ahmad T, Khan T, Tabassum T, Alqahtani YS, Mahnashi MH, Alyami BA, Alqarni AO, Alasmary MY, Almedhesh SA, Shah AJ. Curr Issues Mol Biol 44 3180-3193 (2022)
  311. Yang Z, Marston SB, Gould IR. J Phys Chem B 127 8736-8748 (2023)
  312. Vasile VC, Jaffe AS. Biomark Med 1 491-501 (2007)
  313. Clayton JS, McNamara EL, Goullee H, Conijn S, Muthsam K, Musk GC, Coote D, Kijas J, Testa AC, Taylor RL, O'Hara AJ, Groth D, Ottenheijm C, Ravenscroft G, Laing NG, Nowak KJ. Acta Neuropathol Commun 8 142 (2020)
  314. Sevrieva IR, Ponnam S, Yan Z, Irving M, Kampourakis T, Sun YB. J Biol Chem 299 102767 (2023)
  315. Omar SI, Keasar C, Ben-Sasson AJ, Haber E. Biomolecules 13 457 (2023)
  316. Comment Morimoto S. J Mol Cell Cardiol 47 350-351 (2009)
  317. Susini V, Fierabracci V, Barria G, Dodoli L, Caponi L, Paolicchi A, Franzini M. Biosensors (Basel) 11 493 (2021)
  318. Yumoto F, Tanaka H, Nagata K, Miyauchi Y, Miyakawa T, Ojima T, Tanokura M. Biochem Biophys Res Commun 369 109-114 (2008)
  319. research-article Westfall MV. J Mol Cell Cardiol 72 238-240 (2014)


Related citations provided by authors (2)

  1. . Takeda S, Kobayashi T, Taniguchi H, Hayashi H, Maeda Y Eur. J. Biochem. 246 611-617 (1997)
  2. . Vassylyev DG, Takeda S, Wakatsuki S, Maeda K, Maeda Y Proc. Natl. Acad. Sci. U.S.A. 95 4847-4852 (1998)

Quick links