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Helical reconstruction of the human cardiac actin-tropomyosin-myosin loop 4 7G mutant complex

Source organisms:
Biochemical function: protein binding
Biological process: actin filament organization
Cellular component: sarcomere

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GO terms

Biochemical function:
Biological process:
Cellular component:

Sequence families

Pfam Protein families (Pfam)
PF00022
Domain description: Actin
Occurring in:
  1. Cardiac muscle alpha actin 1
The deposited structure of PDB entry 8enc contains 5 copies of Pfam domain PF00022 (Actin) in Actin, alpha cardiac muscle 1. Showing 1 copy in chain B.

PF00261
Domain description: Tropomyosin
Occurring in:
  1. Tropomyosin alpha-1 chain
The deposited structure of PDB entry 8enc contains 4 copies of Pfam domain PF00261 (Tropomyosin) in Tropomyosin alpha-1 chain. Showing 2 copies in chain G [auth O].

PF01576
Domain description: Myosin tail
Occurring in:
  1. Myosin-7
The deposited structure of PDB entry 8enc contains 1 copy of Pfam domain PF01576 (Myosin tail) in Myosin-7. Showing 1 copy in chain A [auth M] (this domain is out of the observed residue ranges!).

PF00063
Domain description: Myosin head (motor domain)
Occurring in:
  1. Myosin-7
The deposited structure of PDB entry 8enc contains 1 copy of Pfam domain PF00063 (Myosin head (motor domain)) in Myosin-7. Showing 1 copy in chain A [auth M].

PF02736
Domain description: Myosin N-terminal SH3-like domain
Occurring in:
  1. Myosin-7
The deposited structure of PDB entry 8enc contains 1 copy of Pfam domain PF02736 (Myosin N-terminal SH3-like domain) in Myosin-7. Showing 1 copy in chain A [auth M].

InterPro InterPro annotations
IPR004000
Domain description: Actin family
Occurring in:
  1. Cardiac muscle alpha actin 1
IPR000533
Domain description: Tropomyosin
Occurring in:
  1. Tropomyosin alpha-1 chain
IPR004001
Domain description: Actin, conserved site
Occurring in:
  1. Cardiac muscle alpha actin 1
IPR043129
Domain description: ATPase, nucleotide binding domain
Occurring in:
  1. Cardiac muscle alpha actin 1
IPR001609
Domain description: Myosin head, motor domain-like
Occurring in:
  1. Myosin-7
IPR020902
Domain description: Actin/actin-like conserved site
Occurring in:
  1. Cardiac muscle alpha actin 1
IPR014751
Domain description: DNA repair protein XRCC4-like, C-terminal
Occurring in:
  1. Myosin-7
IPR000048
Domain description: IQ motif, EF-hand binding site
Occurring in:
  1. Myosin-7
IPR004009
Domain description: Myosin, N-terminal, SH3-like
Occurring in:
  1. Myosin-7
IPR002928
Domain description: Myosin tail
Occurring in:
  1. Myosin-7
IPR036961
Domain description: Kinesin motor domain superfamily
Occurring in:
  1. Myosin-7
IPR027417
Domain description: P-loop containing nucleoside triphosphate hydrolase
Occurring in:
  1. Myosin-7
IPR008989
Domain description: Myosin S1 fragment, N-terminal
Occurring in:
  1. Myosin-7

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