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Serotonin-bound Serotonin 1A (5-HT1A) receptor-Gi protein complex

Source organisms:
Biochemical function: protein binding
Biological process: G protein-coupled receptor signaling pathway
Cellular component: membrane

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GO terms

Biochemical function:
Biological process:
Cellular component:

Sequence families

Pfam Protein families (Pfam)
PF00400
Domain description: WD domain, G-beta repeat
Occurring in:
  1. Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
The deposited structure of PDB entry 7e2y contains 7 copies of Pfam domain PF00400 (WD domain, G-beta repeat) in Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1. Showing 7 copies in chain B.

PF00001
Domain description: 7 transmembrane receptor (rhodopsin family)
Occurring in:
  1. 5-hydroxytryptamine receptor 1A; Soluble cytochrome b562
The deposited structure of PDB entry 7e2y contains 1 copy of Pfam domain PF00001 (7 transmembrane receptor (rhodopsin family)) in 5-hydroxytryptamine receptor 1A. Showing 1 copy in chain D [auth R].

PF07361
Domain description: Cytochrome b562
Occurring in:
  1. 5-hydroxytryptamine receptor 1A; Soluble cytochrome b562
The deposited structure of PDB entry 7e2y contains 1 copy of Pfam domain PF07361 (Cytochrome b562) in 5-hydroxytryptamine receptor 1A. Showing 1 copy in chain D [auth R] (this domain is out of the observed residue ranges!).

PF00631
Domain description: GGL domain
Occurring in:
  1. Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
The deposited structure of PDB entry 7e2y contains 1 copy of Pfam domain PF00631 (GGL domain) in Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2. Showing 1 copy in chain C [auth G].

PF00503
Domain description: G-protein alpha subunit
Occurring in:
  1. Guanine nucleotide-binding protein G(i) subunit alpha-1
The deposited structure of PDB entry 7e2y contains 1 copy of Pfam domain PF00503 (G-protein alpha subunit) in Guanine nucleotide-binding protein G(i) subunit alpha-1. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR001680
Domain description: WD40 repeat
Occurring in:
  1. Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
IPR000276
Domain description: G protein-coupled receptor, rhodopsin-like
Occurring in:
  1. 5-hydroxytryptamine receptor 1A; Soluble cytochrome b562
IPR001019
Domain description: Guanine nucleotide binding protein (G-protein), alpha subunit
Occurring in:
  1. Guanine nucleotide-binding protein G(i) subunit alpha-1
IPR000610
Domain description: 5-Hydroxytryptamine 1A receptor
Occurring in:
  1. 5-hydroxytryptamine receptor 1A; Soluble cytochrome b562
IPR001408
Domain description: G-protein alpha subunit, group I
Occurring in:
  1. Guanine nucleotide-binding protein G(i) subunit alpha-1
IPR002231
Domain description: 5-hydroxytryptamine receptor family
Occurring in:
  1. 5-hydroxytryptamine receptor 1A; Soluble cytochrome b562
IPR015898
Domain description: G-protein gamma-like domain
Occurring in:
  1. Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
IPR001770
Domain description: G-protein, gamma subunit
Occurring in:
  1. Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
IPR001632
Domain description: G-protein, beta subunit
Occurring in:
  1. Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
IPR020472
Domain description: G-protein beta WD-40 repeat
Occurring in:
  1. Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
IPR036284
Domain description: G-protein gamma-like domain superfamily
Occurring in:
  1. Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
IPR011025
Domain description: G protein alpha subunit, helical insertion
Occurring in:
  1. Guanine nucleotide-binding protein G(i) subunit alpha-1
IPR027417
Domain description: P-loop containing nucleoside triphosphate hydrolase
Occurring in:
  1. Guanine nucleotide-binding protein G(i) subunit alpha-1
IPR017452
Domain description: GPCR, rhodopsin-like, 7TM
Occurring in:
  1. 5-hydroxytryptamine receptor 1A; Soluble cytochrome b562
IPR009155
Domain description: Cytochrome b562
Occurring in:
  1. 5-hydroxytryptamine receptor 1A; Soluble cytochrome b562
IPR010980
Domain description: Cytochrome c/b562
Occurring in:
  1. 5-hydroxytryptamine receptor 1A; Soluble cytochrome b562
IPR019775
Domain description: WD40 repeat, conserved site
Occurring in:
  1. Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
IPR036322
Domain description: WD40-repeat-containing domain superfamily
Occurring in:
  1. Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
IPR016346
Domain description: Guanine nucleotide-binding protein, beta subunit
Occurring in:
  1. Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
IPR015943
Domain description: WD40/YVTN repeat-like-containing domain superfamily
Occurring in:
  1. Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

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