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High-resolution Crystal Structure of a Snake Venom Metalloproteinase from Taiwan Habu

X-ray diffraction
1.35Å resolution
PDB entry 1kuf coloured by chain, front view.
PDB entry 1kuf coloured by chain, side view.
PDB entry 1kuf coloured by chain, top view.
Source organism: Protobothrops mucrosquamatus
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Snake venom metalloproteinase TM-3
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Multimeric state: monomeric
Accessible surface area: 9363.06 Ã…2
Buried surface area: 956.38 Ã…2
Dissociation area: 43.68 Ã…2
Dissociation energy (ΔGdiss): 1.92 kcal/mol
Dissociation entropy (TΔSdiss): 0.88 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-129589

Macromolecules

Snake venom metalloproteinase TM-3
Chain: A
Length: 203 amino acids
Theoretical weight: 23.38 KDa
Source organism: Protobothrops mucrosquamatus
UniProt:
  • Canonical: O57413 (Residues: 190-392; Coverage: 44%)
Pfam: Reprolysin (M12B) family zinc metalloprotease
InterPro:
CATH: Collagenase (Catalytic Domain)
SCOP: Reprolysin-like
Snake venom metalloproteinase TM-3 in PDB entry 1kuf, assembly 1, front view.
Snake venom metalloproteinase TM-3 in PDB entry 1kuf, assembly 1, side view.
Snake venom metalloproteinase TM-3 in PDB entry 1kuf, assembly 1, top view.
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