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Crystal structure of tubulin in complex with L-DM1-SMe

Source organisms:
Biochemical function: metal ion binding
Biological process: microtubule-based process
Cellular component: microtubule cytoskeleton

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GO terms

Sequence families

Pfam Protein families (Pfam)
PF03953
Domain description: Tubulin C-terminal domain
Occurring in:
  1. Tubulin alpha-1B chain
  2. Tubulin beta-2B chain
The deposited structure of PDB entry 7e4q contains 2 copies of Pfam domain PF03953 (Tubulin C-terminal domain) in Tubulin alpha-1B chain. Showing 1 copy in chain C.
The deposited structure of PDB entry 7e4q contains 2 copies of Pfam domain PF03953 (Tubulin C-terminal domain) in Tubulin beta-2B chain. Showing 1 copy in chain B.

PF00091
Domain description: Tubulin/FtsZ family, GTPase domain
Occurring in:
  1. Tubulin alpha-1B chain
  2. Tubulin beta-2B chain
The deposited structure of PDB entry 7e4q contains 2 copies of Pfam domain PF00091 (Tubulin/FtsZ family, GTPase domain) in Tubulin alpha-1B chain. Showing 1 copy in chain C.
The deposited structure of PDB entry 7e4q contains 2 copies of Pfam domain PF00091 (Tubulin/FtsZ family, GTPase domain) in Tubulin beta-2B chain. Showing 1 copy in chain B.

PF00836
Domain description: Stathmin family
Occurring in:
  1. Stathmin-4
The deposited structure of PDB entry 7e4q contains 1 copy of Pfam domain PF00836 (Stathmin family) in Stathmin-4. Showing 1 copy in chain E.

InterPro InterPro annotations
IPR000217
Domain description: Tubulin
Occurring in:
  1. Tubulin alpha-1B chain
  2. Tubulin beta-2B chain
IPR002453
Domain description: Beta tubulin
Occurring in:
  1. Tubulin beta-2B chain
IPR002452
Domain description: Alpha tubulin
Occurring in:
  1. Tubulin alpha-1B chain
IPR000956
Domain description: Stathmin family
Occurring in:
  1. Stathmin-4
IPR018316
Domain description: Tubulin/FtsZ, 2-layer sandwich domain
Occurring in:
  1. Tubulin alpha-1B chain
  2. Tubulin beta-2B chain
IPR003008
Domain description: Tubulin/FtsZ, GTPase domain
Occurring in:
  1. Tubulin alpha-1B chain
  2. Tubulin beta-2B chain
IPR036525
Domain description: Tubulin/FtsZ, GTPase domain superfamily
Occurring in:
  1. Tubulin alpha-1B chain
  2. Tubulin beta-2B chain
IPR023123
Domain description: Tubulin, C-terminal
Occurring in:
  1. Tubulin alpha-1B chain
  2. Tubulin beta-2B chain
IPR037103
Domain description: Tubulin/FtsZ-like, C-terminal domain
Occurring in:
  1. Tubulin alpha-1B chain
  2. Tubulin beta-2B chain
IPR008280
Domain description: Tubulin/FtsZ, C-terminal
Occurring in:
  1. Tubulin alpha-1B chain
  2. Tubulin beta-2B chain
IPR017975
Domain description: Tubulin, conserved site
Occurring in:
  1. Tubulin alpha-1B chain
  2. Tubulin beta-2B chain
IPR004344
Domain description: Tubulin-tyrosine ligase/Tubulin polyglutamylase
Occurring in:
  1. Tubulin tyrosine ligase
IPR030514
Domain description: Stathmin, conserved site
Occurring in:
  1. Stathmin-4
IPR013838
Domain description: Beta tubulin, autoregulation binding site
Occurring in:
  1. Tubulin beta-2B chain
IPR036002
Domain description: Stathmin superfamily
Occurring in:
  1. Stathmin-4

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