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Crystal Structure of Pembrolizumab, a full length IgG4 antibody

Source organism: Homo sapiens
Biochemical function: not assigned
Biological process: not assigned
Cellular component: not assigned

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GO terms

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence family

InterPro InterPro annotations
IPR003597
Domain description: Immunoglobulin C1-set
Occurring in:
  1. Light Chain
  2. Heavy Chain
IPR036179
Domain description: Immunoglobulin-like domain superfamily
Occurring in:
  1. Light Chain
  2. Heavy Chain
IPR013783
Domain description: Immunoglobulin-like fold
Occurring in:
  1. Light Chain
  2. Heavy Chain
IPR007110
Domain description: Immunoglobulin-like domain
Occurring in:
  1. Light Chain
  2. Heavy Chain
IPR003599
Domain description: Immunoglobulin domain subtype
Occurring in:
  1. Light Chain
  2. Heavy Chain
IPR013106
Domain description: Immunoglobulin V-set domain
Occurring in:
  1. Light Chain
  2. Heavy Chain
IPR003006
Domain description: Immunoglobulin/major histocompatibility complex, conserved site
Occurring in:
  1. Light Chain
  2. Heavy Chain

Structure domain

CATH CATH domain
2.60.40.10
Class: Mainly Beta
Architecture: Sandwich
Topology: Immunoglobulin-like
Homology: Immunoglobulins
Occurring in:
  1. Light Chain
  2. Heavy Chain
The deposited structure of PDB entry 5dk3 contains 4 copies of CATH domain 2.60.40.10 (Immunoglobulin-like) in Light Chain. Showing 2 copies in chain A.
The deposited structure of PDB entry 5dk3 contains 2 copies of CATH domain 2.60.40.10 (Immunoglobulin-like) in Heavy Chain. Showing 2 copies in chain D [auth G].

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