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Structural basis for Ca2+-mediated interaction of the perforin C2 domain with lipid membranes

Source organism: Mus musculus
Biochemical function: not assigned
Biological process: not assigned
Cellular component: not assigned

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GO terms

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF00168
Domain description: C2 domain
Occurring in:
  1. Perforin-1
The deposited structure of PDB entry 4y1t contains 1 copy of Pfam domain PF00168 (C2 domain) in Perforin-1. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR000008
Domain description: C2 domain
Occurring in:
  1. Perforin-1
IPR035892
Domain description: C2 domain superfamily
Occurring in:
  1. Perforin-1

Structure domain

CATH CATH domain
2.60.40.150
Class: Mainly Beta
Architecture: Sandwich
Topology: Immunoglobulin-like
Homology: C2 domain
Occurring in:
  1. Perforin-1
The deposited structure of PDB entry 4y1t contains 1 copy of CATH domain 2.60.40.150 (Immunoglobulin-like) in Perforin-1. Showing 1 copy in chain A.

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