data_1KUG
#
_entry.id 1KUG
#
loop_
_citation.id
_citation.title
_citation.journal_abbrev
_citation.journal_volume
_citation.page_first
_citation.page_last
_citation.year
_citation.journal_id_ASTM
_citation.country
_citation.journal_id_ISSN
_citation.journal_id_CSD
_citation.book_publisher
_citation.pdbx_database_id_PubMed
_citation.pdbx_database_id_DOI
primary 'Determinants of the inhibition of a Taiwan habu venom metalloproteinase by its endogenous inhibitors revealed by X-ray crystallography and synthetic inhibitor analogues.' 'Eur. J. Biochem.' 269 3047 3056 2002 EJBCAI IX 0014-2956 0262 ? 12071970 10.1046/j.1432-1033.2002.02982.x
1 'Characterization of multiple metalloproteinases with fibrinogenolytic activity from the venom of Taiwan habu (Trimeresurus mucrosquamatus): protein microsequencing coupled with cDNA sequence analysis.' Biochem.Biophys.Res.Commun. 216 223 233 1995 BBRCA9 US 0006-291X 0146 ? ? 10.1006/bbrc.1995.2614
#
loop_
_citation_author.citation_id
_citation_author.name
_citation_author.ordinal
_citation_author.identifier_ORCID
primary 'Huang, K.F.' 1 ?
primary 'Chiou, S.H.' 2 ?
primary 'Ko, T.P.' 3 ?
primary 'Wang, A.H.' 4 ?
1 'Huang, K.F.' 5 ?
1 'Hung, C.C.' 6 ?
1 'pan, F.M.' 7 ?
1 'Chow, L.P.' 8 ?
1 'Tsugita, A.' 9 ?
1 'Chiou, S.H.' 10 ?
#
loop_
_entity.id
_entity.type
_entity.src_method
_entity.pdbx_description
_entity.formula_weight
_entity.pdbx_number_of_molecules
_entity.pdbx_ec
_entity.pdbx_mutation
_entity.pdbx_fragment
_entity.details
1 polymer nat metalloproteinase 23364.824 1 3.4.24.44 ? 'CATALYTIC PROTEASE DOMAIN' ?
2 polymer syn ENW 429.427 1 ? ? ? ?
3 non-polymer syn 'CADMIUM ION' 112.411 11 ? ? ? ?
4 water nat water 18.015 630 ? ? ? ?
#
_entity_name_com.entity_id 1
_entity_name_com.name 'Atrolysin e'
#
loop_
_entity_poly.entity_id
_entity_poly.type
_entity_poly.nstd_linkage
_entity_poly.nstd_monomer
_entity_poly.pdbx_seq_one_letter_code
_entity_poly.pdbx_seq_one_letter_code_can
_entity_poly.pdbx_strand_id
_entity_poly.pdbx_target_identifier
1 'polypeptide(L)' no no
;EQQRFPQRYIELAIVVDHGMYTKYSSNFKKIRKRVHQMVSNINEMCRPLNIAITLALLDVWSEKDFITVQADAPTTAGLF
GDWRERVLLKKKNHDHAQLLTDTNFARNTIGWAYVGRMCDEKYSVAVVKDHSSKVFMVAVTMTHELGHNLGMEHDDKDKC
KCTTCIMSAVISDKQSKLFSDCSKDYYQTFLTNDNPQCILNAP
;
;EQQRFPQRYIELAIVVDHGMYTKYSSNFKKIRKRVHQMVSNINEMCRPLNIAITLALLDVWSEKDFITVQADAPTTAGLF
GDWRERVLLKKKNHDHAQLLTDTNFARNTIGWAYVGRMCDEKYSVAVVKDHSSKVFMVAVTMTHELGHNLGMEHDDKDKC
KCTTCIMSAVISDKQSKLFSDCSKDYYQTFLTNDNPQCILNAP
;
A ?
2 'polypeptide(L)' no yes '(PCA)NW' QNW B ?
#
loop_
_pdbx_entity_nonpoly.entity_id
_pdbx_entity_nonpoly.name
_pdbx_entity_nonpoly.comp_id
3 'CADMIUM ION' CD
4 water HOH
#
loop_
_entity_poly_seq.entity_id
_entity_poly_seq.num
_entity_poly_seq.mon_id
_entity_poly_seq.hetero
1 1 GLU n
1 2 GLN n
1 3 GLN n
1 4 ARG n
1 5 PHE n
1 6 PRO n
1 7 GLN n
1 8 ARG n
1 9 TYR n
1 10 ILE n
1 11 GLU n
1 12 LEU n
1 13 ALA n
1 14 ILE n
1 15 VAL n
1 16 VAL n
1 17 ASP n
1 18 HIS n
1 19 GLY n
1 20 MET n
1 21 TYR n
1 22 THR n
1 23 LYS n
1 24 TYR n
1 25 SER n
1 26 SER n
1 27 ASN n
1 28 PHE n
1 29 LYS n
1 30 LYS n
1 31 ILE n
1 32 ARG n
1 33 LYS n
1 34 ARG n
1 35 VAL n
1 36 HIS n
1 37 GLN n
1 38 MET n
1 39 VAL n
1 40 SER n
1 41 ASN n
1 42 ILE n
1 43 ASN n
1 44 GLU n
1 45 MET n
1 46 CYS n
1 47 ARG n
1 48 PRO n
1 49 LEU n
1 50 ASN n
1 51 ILE n
1 52 ALA n
1 53 ILE n
1 54 THR n
1 55 LEU n
1 56 ALA n
1 57 LEU n
1 58 LEU n
1 59 ASP n
1 60 VAL n
1 61 TRP n
1 62 SER n
1 63 GLU n
1 64 LYS n
1 65 ASP n
1 66 PHE n
1 67 ILE n
1 68 THR n
1 69 VAL n
1 70 GLN n
1 71 ALA n
1 72 ASP n
1 73 ALA n
1 74 PRO n
1 75 THR n
1 76 THR n
1 77 ALA n
1 78 GLY n
1 79 LEU n
1 80 PHE n
1 81 GLY n
1 82 ASP n
1 83 TRP n
1 84 ARG n
1 85 GLU n
1 86 ARG n
1 87 VAL n
1 88 LEU n
1 89 LEU n
1 90 LYS n
1 91 LYS n
1 92 LYS n
1 93 ASN n
1 94 HIS n
1 95 ASP n
1 96 HIS n
1 97 ALA n
1 98 GLN n
1 99 LEU n
1 100 LEU n
1 101 THR n
1 102 ASP n
1 103 THR n
1 104 ASN n
1 105 PHE n
1 106 ALA n
1 107 ARG n
1 108 ASN n
1 109 THR n
1 110 ILE n
1 111 GLY n
1 112 TRP n
1 113 ALA n
1 114 TYR n
1 115 VAL n
1 116 GLY n
1 117 ARG n
1 118 MET n
1 119 CYS n
1 120 ASP n
1 121 GLU n
1 122 LYS n
1 123 TYR n
1 124 SER n
1 125 VAL n
1 126 ALA n
1 127 VAL n
1 128 VAL n
1 129 LYS n
1 130 ASP n
1 131 HIS n
1 132 SER n
1 133 SER n
1 134 LYS n
1 135 VAL n
1 136 PHE n
1 137 MET n
1 138 VAL n
1 139 ALA n
1 140 VAL n
1 141 THR n
1 142 MET n
1 143 THR n
1 144 HIS n
1 145 GLU n
1 146 LEU n
1 147 GLY n
1 148 HIS n
1 149 ASN n
1 150 LEU n
1 151 GLY n
1 152 MET n
1 153 GLU n
1 154 HIS n
1 155 ASP n
1 156 ASP n
1 157 LYS n
1 158 ASP n
1 159 LYS n
1 160 CYS n
1 161 LYS n
1 162 CYS n
1 163 THR n
1 164 THR n
1 165 CYS n
1 166 ILE n
1 167 MET n
1 168 SER n
1 169 ALA n
1 170 VAL n
1 171 ILE n
1 172 SER n
1 173 ASP n
1 174 LYS n
1 175 GLN n
1 176 SER n
1 177 LYS n
1 178 LEU n
1 179 PHE n
1 180 SER n
1 181 ASP n
1 182 CYS n
1 183 SER n
1 184 LYS n
1 185 ASP n
1 186 TYR n
1 187 TYR n
1 188 GLN n
1 189 THR n
1 190 PHE n
1 191 LEU n
1 192 THR n
1 193 ASN n
1 194 ASP n
1 195 ASN n
1 196 PRO n
1 197 GLN n
1 198 CYS n
1 199 ILE n
1 200 LEU n
1 201 ASN n
1 202 ALA n
1 203 PRO n
2 1 PCA n
2 2 ASN n
2 3 TRP n
#
_entity_src_nat.entity_id 1
_entity_src_nat.pdbx_src_id 1
_entity_src_nat.pdbx_alt_source_flag sample
_entity_src_nat.pdbx_beg_seq_num ?
_entity_src_nat.pdbx_end_seq_num ?
_entity_src_nat.common_name ?
_entity_src_nat.pdbx_organism_scientific 'Protobothrops mucrosquamatus'
_entity_src_nat.pdbx_ncbi_taxonomy_id 103944
_entity_src_nat.genus Protobothrops
_entity_src_nat.species ?
_entity_src_nat.strain ?
_entity_src_nat.tissue ?
_entity_src_nat.tissue_fraction ?
_entity_src_nat.pdbx_secretion ?
_entity_src_nat.pdbx_fragment ?
_entity_src_nat.pdbx_variant ?
_entity_src_nat.pdbx_cell_line ?
_entity_src_nat.pdbx_atcc ?
_entity_src_nat.pdbx_cellular_location ?
_entity_src_nat.pdbx_organ ?
_entity_src_nat.pdbx_organelle ?
_entity_src_nat.pdbx_cell ?
_entity_src_nat.pdbx_plasmid_name ?
_entity_src_nat.pdbx_plasmid_details ?
_entity_src_nat.details ?
#
_pdbx_entity_src_syn.entity_id 2
_pdbx_entity_src_syn.pdbx_src_id 1
_pdbx_entity_src_syn.pdbx_alt_source_flag sample
_pdbx_entity_src_syn.pdbx_beg_seq_num ?
_pdbx_entity_src_syn.pdbx_end_seq_num ?
_pdbx_entity_src_syn.organism_scientific ?
_pdbx_entity_src_syn.organism_common_name ?
_pdbx_entity_src_syn.ncbi_taxonomy_id ?
_pdbx_entity_src_syn.details 'The inhibitor pENW was synthesized by solid-phase method.'
#
loop_
_chem_comp.id
_chem_comp.type
_chem_comp.mon_nstd_flag
_chem_comp.name
_chem_comp.pdbx_synonyms
_chem_comp.formula
_chem_comp.formula_weight
ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2' 89.093
ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209
ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3' 132.118
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4' 133.103
CD non-polymer . 'CADMIUM ION' ? 'Cd 2' 112.411
CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S' 121.158
GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3' 146.144
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4' 147.129
GLY 'peptide linking' y GLYCINE ? 'C2 H5 N O2' 75.067
HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162
HOH non-polymer . WATER ? 'H2 O' 18.015
ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2' 131.173
LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2' 131.173
LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195
MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S' 149.211
PCA 'L-peptide linking' n 'PYROGLUTAMIC ACID' ? 'C5 H7 N O3' 129.114
PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2' 165.189
PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2' 115.130
SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3' 105.093
THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3' 119.119
TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2' 204.225
TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3' 181.189
VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2' 117.146
#
loop_
_pdbx_poly_seq_scheme.asym_id
_pdbx_poly_seq_scheme.entity_id
_pdbx_poly_seq_scheme.seq_id
_pdbx_poly_seq_scheme.mon_id
_pdbx_poly_seq_scheme.ndb_seq_num
_pdbx_poly_seq_scheme.pdb_seq_num
_pdbx_poly_seq_scheme.auth_seq_num
_pdbx_poly_seq_scheme.pdb_mon_id
_pdbx_poly_seq_scheme.auth_mon_id
_pdbx_poly_seq_scheme.pdb_strand_id
_pdbx_poly_seq_scheme.pdb_ins_code
_pdbx_poly_seq_scheme.hetero
A 1 1 GLU 1 1 ? ? ? A . n
A 1 2 GLN 2 2 ? ? ? A . n
A 1 3 GLN 3 3 3 GLN GLN A . n
A 1 4 ARG 4 4 4 ARG ARG A . n
A 1 5 PHE 5 5 5 PHE PHE A . n
A 1 6 PRO 6 6 6 PRO PRO A . n
A 1 7 GLN 7 7 7 GLN GLN A . n
A 1 8 ARG 8 8 8 ARG ARG A . n
A 1 9 TYR 9 9 9 TYR TYR A . n
A 1 10 ILE 10 10 10 ILE ILE A . n
A 1 11 GLU 11 11 11 GLU GLU A . n
A 1 12 LEU 12 12 12 LEU LEU A . n
A 1 13 ALA 13 13 13 ALA ALA A . n
A 1 14 ILE 14 14 14 ILE ILE A . n
A 1 15 VAL 15 15 15 VAL VAL A . n
A 1 16 VAL 16 16 16 VAL VAL A . n
A 1 17 ASP 17 17 17 ASP ASP A . n
A 1 18 HIS 18 18 18 HIS HIS A . n
A 1 19 GLY 19 19 19 GLY GLY A . n
A 1 20 MET 20 20 20 MET MET A . n
A 1 21 TYR 21 21 21 TYR TYR A . n
A 1 22 THR 22 22 22 THR THR A . n
A 1 23 LYS 23 23 23 LYS LYS A . n
A 1 24 TYR 24 24 24 TYR TYR A . n
A 1 25 SER 25 25 25 SER SER A . n
A 1 26 SER 26 26 26 SER SER A . n
A 1 27 ASN 27 27 27 ASN ASN A . n
A 1 28 PHE 28 28 28 PHE PHE A . n
A 1 29 LYS 29 29 29 LYS LYS A . n
A 1 30 LYS 30 30 30 LYS LYS A . n
A 1 31 ILE 31 31 31 ILE ILE A . n
A 1 32 ARG 32 32 32 ARG ARG A . n
A 1 33 LYS 33 33 33 LYS LYS A . n
A 1 34 ARG 34 34 34 ARG ARG A . n
A 1 35 VAL 35 35 35 VAL VAL A . n
A 1 36 HIS 36 36 36 HIS HIS A . n
A 1 37 GLN 37 37 37 GLN GLN A . n
A 1 38 MET 38 38 38 MET MET A . n
A 1 39 VAL 39 39 39 VAL VAL A . n
A 1 40 SER 40 40 40 SER SER A . n
A 1 41 ASN 41 41 41 ASN ASN A . n
A 1 42 ILE 42 42 42 ILE ILE A . n
A 1 43 ASN 43 43 43 ASN ASN A . n
A 1 44 GLU 44 44 44 GLU GLU A . n
A 1 45 MET 45 45 45 MET MET A . n
A 1 46 CYS 46 46 46 CYS CYS A . n
A 1 47 ARG 47 47 47 ARG ARG A . n
A 1 48 PRO 48 48 48 PRO PRO A . n
A 1 49 LEU 49 49 49 LEU LEU A . n
A 1 50 ASN 50 50 50 ASN ASN A . n
A 1 51 ILE 51 51 51 ILE ILE A . n
A 1 52 ALA 52 52 52 ALA ALA A . n
A 1 53 ILE 53 53 53 ILE ILE A . n
A 1 54 THR 54 54 54 THR THR A . n
A 1 55 LEU 55 55 55 LEU LEU A . n
A 1 56 ALA 56 56 56 ALA ALA A . n
A 1 57 LEU 57 57 57 LEU LEU A . n
A 1 58 LEU 58 58 58 LEU LEU A . n
A 1 59 ASP 59 59 59 ASP ASP A . n
A 1 60 VAL 60 60 60 VAL VAL A . n
A 1 61 TRP 61 61 61 TRP TRP A . n
A 1 62 SER 62 62 62 SER SER A . n
A 1 63 GLU 63 63 63 GLU GLU A . n
A 1 64 LYS 64 64 64 LYS LYS A . n
A 1 65 ASP 65 65 65 ASP ASP A . n
A 1 66 PHE 66 66 66 PHE PHE A . n
A 1 67 ILE 67 67 67 ILE ILE A . n
A 1 68 THR 68 68 68 THR THR A . n
A 1 69 VAL 69 69 69 VAL VAL A . n
A 1 70 GLN 70 70 70 GLN GLN A . n
A 1 71 ALA 71 71 71 ALA ALA A . n
A 1 72 ASP 72 72 72 ASP ASP A . n
A 1 73 ALA 73 73 73 ALA ALA A . n
A 1 74 PRO 74 74 74 PRO PRO A . n
A 1 75 THR 75 75 75 THR THR A . n
A 1 76 THR 76 76 76 THR THR A . n
A 1 77 ALA 77 77 77 ALA ALA A . n
A 1 78 GLY 78 78 78 GLY GLY A . n
A 1 79 LEU 79 79 79 LEU LEU A . n
A 1 80 PHE 80 80 80 PHE PHE A . n
A 1 81 GLY 81 81 81 GLY GLY A . n
A 1 82 ASP 82 82 82 ASP ASP A . n
A 1 83 TRP 83 83 83 TRP TRP A . n
A 1 84 ARG 84 84 84 ARG ARG A . n
A 1 85 GLU 85 85 85 GLU GLU A . n
A 1 86 ARG 86 86 86 ARG ARG A . n
A 1 87 VAL 87 87 87 VAL VAL A . n
A 1 88 LEU 88 88 88 LEU LEU A . n
A 1 89 LEU 89 89 89 LEU LEU A . n
A 1 90 LYS 90 90 90 LYS LYS A . n
A 1 91 LYS 91 91 91 LYS LYS A . n
A 1 92 LYS 92 92 92 LYS LYS A . n
A 1 93 ASN 93 93 93 ASN ASN A . n
A 1 94 HIS 94 94 94 HIS HIS A . n
A 1 95 ASP 95 95 95 ASP ASP A . n
A 1 96 HIS 96 96 96 HIS HIS A . n
A 1 97 ALA 97 97 97 ALA ALA A . n
A 1 98 GLN 98 98 98 GLN GLN A . n
A 1 99 LEU 99 99 99 LEU LEU A . n
A 1 100 LEU 100 100 100 LEU LEU A . n
A 1 101 THR 101 101 101 THR THR A . n
A 1 102 ASP 102 102 102 ASP ASP A . n
A 1 103 THR 103 103 103 THR THR A . n
A 1 104 ASN 104 104 104 ASN ASN A . n
A 1 105 PHE 105 105 105 PHE PHE A . n
A 1 106 ALA 106 106 106 ALA ALA A . n
A 1 107 ARG 107 107 107 ARG ARG A . n
A 1 108 ASN 108 108 108 ASN ASN A . n
A 1 109 THR 109 109 109 THR THR A . n
A 1 110 ILE 110 110 110 ILE ILE A . n
A 1 111 GLY 111 111 111 GLY GLY A . n
A 1 112 TRP 112 112 112 TRP TRP A . n
A 1 113 ALA 113 113 113 ALA ALA A . n
A 1 114 TYR 114 114 114 TYR TYR A . n
A 1 115 VAL 115 115 115 VAL VAL A . n
A 1 116 GLY 116 116 116 GLY GLY A . n
A 1 117 ARG 117 117 117 ARG ARG A . n
A 1 118 MET 118 118 118 MET MET A . n
A 1 119 CYS 119 119 119 CYS CYS A . n
A 1 120 ASP 120 120 120 ASP ASP A . n
A 1 121 GLU 121 121 121 GLU GLU A . n
A 1 122 LYS 122 122 122 LYS LYS A . n
A 1 123 TYR 123 123 123 TYR TYR A . n
A 1 124 SER 124 124 124 SER SER A . n
A 1 125 VAL 125 125 125 VAL VAL A . n
A 1 126 ALA 126 126 126 ALA ALA A . n
A 1 127 VAL 127 127 127 VAL VAL A . n
A 1 128 VAL 128 128 128 VAL VAL A . n
A 1 129 LYS 129 129 129 LYS LYS A . n
A 1 130 ASP 130 130 130 ASP ASP A . n
A 1 131 HIS 131 131 131 HIS HIS A . n
A 1 132 SER 132 132 132 SER SER A . n
A 1 133 SER 133 133 133 SER SER A . n
A 1 134 LYS 134 134 134 LYS LYS A . n
A 1 135 VAL 135 135 135 VAL VAL A . n
A 1 136 PHE 136 136 136 PHE PHE A . n
A 1 137 MET 137 137 137 MET MET A . n
A 1 138 VAL 138 138 138 VAL VAL A . n
A 1 139 ALA 139 139 139 ALA ALA A . n
A 1 140 VAL 140 140 140 VAL VAL A . n
A 1 141 THR 141 141 141 THR THR A . n
A 1 142 MET 142 142 142 MET MET A . n
A 1 143 THR 143 143 143 THR THR A . n
A 1 144 HIS 144 144 144 HIS HIS A . n
A 1 145 GLU 145 145 145 GLU GLU A . n
A 1 146 LEU 146 146 146 LEU LEU A . n
A 1 147 GLY 147 147 147 GLY GLY A . n
A 1 148 HIS 148 148 148 HIS HIS A . n
A 1 149 ASN 149 149 149 ASN ASN A . n
A 1 150 LEU 150 150 150 LEU LEU A . n
A 1 151 GLY 151 151 151 GLY GLY A . n
A 1 152 MET 152 152 152 MET MET A . n
A 1 153 GLU 153 153 153 GLU GLU A . n
A 1 154 HIS 154 154 154 HIS HIS A . n
A 1 155 ASP 155 155 155 ASP ASP A . n
A 1 156 ASP 156 156 156 ASP ASP A . n
A 1 157 LYS 157 157 157 LYS LYS A . n
A 1 158 ASP 158 158 158 ASP ASP A . n
A 1 159 LYS 159 159 159 LYS LYS A . n
A 1 160 CYS 160 160 160 CYS CYS A . n
A 1 161 LYS 161 161 161 LYS LYS A . n
A 1 162 CYS 162 162 162 CYS CYS A . n
A 1 163 THR 163 163 163 THR THR A . n
A 1 164 THR 164 164 164 THR THR A . n
A 1 165 CYS 165 165 165 CYS CYS A . n
A 1 166 ILE 166 166 166 ILE ILE A . n
A 1 167 MET 167 167 167 MET MET A . n
A 1 168 SER 168 168 168 SER SER A . n
A 1 169 ALA 169 169 169 ALA ALA A . n
A 1 170 VAL 170 170 170 VAL VAL A . n
A 1 171 ILE 171 171 171 ILE ILE A . n
A 1 172 SER 172 172 172 SER SER A . n
A 1 173 ASP 173 173 173 ASP ASP A . n
A 1 174 LYS 174 174 174 LYS LYS A . n
A 1 175 GLN 175 175 175 GLN GLN A . n
A 1 176 SER 176 176 176 SER SER A . n
A 1 177 LYS 177 177 177 LYS LYS A . n
A 1 178 LEU 178 178 178 LEU LEU A . n
A 1 179 PHE 179 179 179 PHE PHE A . n
A 1 180 SER 180 180 180 SER SER A . n
A 1 181 ASP 181 181 181 ASP ASP A . n
A 1 182 CYS 182 182 182 CYS CYS A . n
A 1 183 SER 183 183 183 SER SER A . n
A 1 184 LYS 184 184 184 LYS LYS A . n
A 1 185 ASP 185 185 185 ASP ASP A . n
A 1 186 TYR 186 186 186 TYR TYR A . n
A 1 187 TYR 187 187 187 TYR TYR A . n
A 1 188 GLN 188 188 188 GLN GLN A . n
A 1 189 THR 189 189 189 THR THR A . n
A 1 190 PHE 190 190 190 PHE PHE A . n
A 1 191 LEU 191 191 191 LEU LEU A . n
A 1 192 THR 192 192 192 THR THR A . n
A 1 193 ASN 193 193 193 ASN ASN A . n
A 1 194 ASP 194 194 194 ASP ASP A . n
A 1 195 ASN 195 195 195 ASN ASN A . n
A 1 196 PRO 196 196 196 PRO PRO A . n
A 1 197 GLN 197 197 197 GLN GLN A . n
A 1 198 CYS 198 198 198 CYS CYS A . n
A 1 199 ILE 199 199 199 ILE ILE A . n
A 1 200 LEU 200 200 200 LEU LEU A . n
A 1 201 ASN 201 201 201 ASN ASN A . n
A 1 202 ALA 202 202 202 ALA ALA A . n
A 1 203 PRO 203 203 203 PRO PRO A . n
B 2 1 PCA 1 251 251 PCA PCA B . n
B 2 2 ASN 2 252 252 ASN ASN B . n
B 2 3 TRP 3 253 253 TRP TRP B . n
#
loop_
_pdbx_nonpoly_scheme.asym_id
_pdbx_nonpoly_scheme.entity_id
_pdbx_nonpoly_scheme.mon_id
_pdbx_nonpoly_scheme.ndb_seq_num
_pdbx_nonpoly_scheme.pdb_seq_num
_pdbx_nonpoly_scheme.auth_seq_num
_pdbx_nonpoly_scheme.pdb_mon_id
_pdbx_nonpoly_scheme.auth_mon_id
_pdbx_nonpoly_scheme.pdb_strand_id
_pdbx_nonpoly_scheme.pdb_ins_code
C 3 CD 1 981 981 CD CD A .
D 3 CD 1 982 982 CD CD A .
E 3 CD 1 983 983 CD CD A .
F 3 CD 1 984 984 CD CD A .
G 3 CD 1 985 985 CD CD A .
H 3 CD 1 986 986 CD CD A .
I 3 CD 1 987 987 CD CD A .
J 3 CD 1 988 988 CD CD A .
K 3 CD 1 989 989 CD CD A .
L 3 CD 1 990 990 CD CD A .
M 3 CD 1 991 991 CD CD A .
N 4 HOH 1 301 301 HOH HOH A .
N 4 HOH 2 302 302 HOH HOH A .
N 4 HOH 3 303 303 HOH HOH A .
N 4 HOH 4 304 304 HOH HOH A .
N 4 HOH 5 305 305 HOH HOH A .
N 4 HOH 6 306 306 HOH HOH A .
N 4 HOH 7 307 307 HOH HOH A .
N 4 HOH 8 308 308 HOH HOH A .
N 4 HOH 9 309 309 HOH HOH A .
N 4 HOH 10 310 310 HOH HOH A .
N 4 HOH 11 311 311 HOH HOH A .
N 4 HOH 12 312 312 HOH HOH A .
N 4 HOH 13 313 313 HOH HOH A .
N 4 HOH 14 314 314 HOH HOH A .
N 4 HOH 15 315 315 HOH HOH A .
N 4 HOH 16 316 316 HOH HOH A .
N 4 HOH 17 317 317 HOH HOH A .
N 4 HOH 18 318 318 HOH HOH A .
N 4 HOH 19 319 319 HOH HOH A .
N 4 HOH 20 320 320 HOH HOH A .
N 4 HOH 21 321 321 HOH HOH A .
N 4 HOH 22 322 322 HOH HOH A .
N 4 HOH 23 323 323 HOH HOH A .
N 4 HOH 24 324 324 HOH HOH A .
N 4 HOH 25 325 325 HOH HOH A .
N 4 HOH 26 326 326 HOH HOH A .
N 4 HOH 27 327 327 HOH HOH A .
N 4 HOH 28 328 328 HOH HOH A .
N 4 HOH 29 329 329 HOH HOH A .
N 4 HOH 30 330 330 HOH HOH A .
N 4 HOH 31 331 331 HOH HOH A .
N 4 HOH 32 332 332 HOH HOH A .
N 4 HOH 33 333 333 HOH HOH A .
N 4 HOH 34 334 334 HOH HOH A .
N 4 HOH 35 335 335 HOH HOH A .
N 4 HOH 36 336 336 HOH HOH A .
N 4 HOH 37 337 337 HOH HOH A .
N 4 HOH 38 338 338 HOH HOH A .
N 4 HOH 39 339 339 HOH HOH A .
N 4 HOH 40 340 340 HOH HOH A .
N 4 HOH 41 341 341 HOH HOH A .
N 4 HOH 42 342 342 HOH HOH A .
N 4 HOH 43 343 343 HOH HOH A .
N 4 HOH 44 344 344 HOH HOH A .
N 4 HOH 45 345 345 HOH HOH A .
N 4 HOH 46 346 346 HOH HOH A .
N 4 HOH 47 347 347 HOH HOH A .
N 4 HOH 48 348 348 HOH HOH A .
N 4 HOH 49 349 349 HOH HOH A .
N 4 HOH 50 350 350 HOH HOH A .
N 4 HOH 51 351 351 HOH HOH A .
N 4 HOH 52 352 352 HOH HOH A .
N 4 HOH 53 353 353 HOH HOH A .
N 4 HOH 54 354 354 HOH HOH A .
N 4 HOH 55 355 355 HOH HOH A .
N 4 HOH 56 356 356 HOH HOH A .
N 4 HOH 57 357 357 HOH HOH A .
N 4 HOH 58 358 358 HOH HOH A .
N 4 HOH 59 359 359 HOH HOH A .
N 4 HOH 60 360 360 HOH HOH A .
N 4 HOH 61 361 361 HOH HOH A .
N 4 HOH 62 362 362 HOH HOH A .
N 4 HOH 63 363 363 HOH HOH A .
N 4 HOH 64 364 364 HOH HOH A .
N 4 HOH 65 365 365 HOH HOH A .
N 4 HOH 66 366 366 HOH HOH A .
N 4 HOH 67 367 367 HOH HOH A .
N 4 HOH 68 368 368 HOH HOH A .
N 4 HOH 69 369 369 HOH HOH A .
N 4 HOH 70 370 370 HOH HOH A .
N 4 HOH 71 371 371 HOH HOH A .
N 4 HOH 72 372 372 HOH HOH A .
N 4 HOH 73 373 373 HOH HOH A .
N 4 HOH 74 374 374 HOH HOH A .
N 4 HOH 75 375 375 HOH HOH A .
N 4 HOH 76 376 376 HOH HOH A .
N 4 HOH 77 377 377 HOH HOH A .
N 4 HOH 78 378 378 HOH HOH A .
N 4 HOH 79 379 379 HOH HOH A .
N 4 HOH 80 380 380 HOH HOH A .
N 4 HOH 81 381 381 HOH HOH A .
N 4 HOH 82 382 382 HOH HOH A .
N 4 HOH 83 383 383 HOH HOH A .
N 4 HOH 84 384 384 HOH HOH A .
N 4 HOH 85 385 385 HOH HOH A .
N 4 HOH 86 386 386 HOH HOH A .
N 4 HOH 87 387 387 HOH HOH A .
N 4 HOH 88 388 388 HOH HOH A .
N 4 HOH 89 389 389 HOH HOH A .
N 4 HOH 90 390 390 HOH HOH A .
N 4 HOH 91 391 391 HOH HOH A .
N 4 HOH 92 392 392 HOH HOH A .
N 4 HOH 93 393 393 HOH HOH A .
N 4 HOH 94 394 394 HOH HOH A .
N 4 HOH 95 395 395 HOH HOH A .
N 4 HOH 96 396 396 HOH HOH A .
N 4 HOH 97 397 397 HOH HOH A .
N 4 HOH 98 398 398 HOH HOH A .
N 4 HOH 99 399 399 HOH HOH A .
N 4 HOH 100 400 400 HOH HOH A .
N 4 HOH 101 401 401 HOH HOH A .
N 4 HOH 102 402 402 HOH HOH A .
N 4 HOH 103 403 403 HOH HOH A .
N 4 HOH 104 404 404 HOH HOH A .
N 4 HOH 105 405 405 HOH HOH A .
N 4 HOH 106 406 406 HOH HOH A .
N 4 HOH 107 407 407 HOH HOH A .
N 4 HOH 108 408 408 HOH HOH A .
N 4 HOH 109 409 409 HOH HOH A .
N 4 HOH 110 410 410 HOH HOH A .
N 4 HOH 111 411 411 HOH HOH A .
N 4 HOH 112 414 414 HOH HOH A .
N 4 HOH 113 415 415 HOH HOH A .
N 4 HOH 114 416 416 HOH HOH A .
N 4 HOH 115 417 417 HOH HOH A .
N 4 HOH 116 418 418 HOH HOH A .
N 4 HOH 117 419 419 HOH HOH A .
N 4 HOH 118 420 420 HOH HOH A .
N 4 HOH 119 421 421 HOH HOH A .
N 4 HOH 120 422 422 HOH HOH A .
N 4 HOH 121 423 423 HOH HOH A .
N 4 HOH 122 424 424 HOH HOH A .
N 4 HOH 123 425 425 HOH HOH A .
N 4 HOH 124 426 426 HOH HOH A .
N 4 HOH 125 427 427 HOH HOH A .
N 4 HOH 126 428 428 HOH HOH A .
N 4 HOH 127 429 429 HOH HOH A .
N 4 HOH 128 430 430 HOH HOH A .
N 4 HOH 129 431 431 HOH HOH A .
N 4 HOH 130 432 432 HOH HOH A .
N 4 HOH 131 433 433 HOH HOH A .
N 4 HOH 132 434 434 HOH HOH A .
N 4 HOH 133 435 435 HOH HOH A .
N 4 HOH 134 436 436 HOH HOH A .
N 4 HOH 135 437 437 HOH HOH A .
N 4 HOH 136 438 438 HOH HOH A .
N 4 HOH 137 439 439 HOH HOH A .
N 4 HOH 138 440 440 HOH HOH A .
N 4 HOH 139 441 441 HOH HOH A .
N 4 HOH 140 442 442 HOH HOH A .
N 4 HOH 141 443 443 HOH HOH A .
N 4 HOH 142 444 444 HOH HOH A .
N 4 HOH 143 445 445 HOH HOH A .
N 4 HOH 144 446 446 HOH HOH A .
N 4 HOH 145 447 447 HOH HOH A .
N 4 HOH 146 448 448 HOH HOH A .
N 4 HOH 147 449 449 HOH HOH A .
N 4 HOH 148 450 450 HOH HOH A .
N 4 HOH 149 451 451 HOH HOH A .
N 4 HOH 150 452 452 HOH HOH A .
N 4 HOH 151 453 453 HOH HOH A .
N 4 HOH 152 454 454 HOH HOH A .
N 4 HOH 153 455 455 HOH HOH A .
N 4 HOH 154 456 456 HOH HOH A .
N 4 HOH 155 457 457 HOH HOH A .
N 4 HOH 156 458 458 HOH HOH A .
N 4 HOH 157 459 459 HOH HOH A .
N 4 HOH 158 460 460 HOH HOH A .
N 4 HOH 159 461 461 HOH HOH A .
N 4 HOH 160 462 462 HOH HOH A .
N 4 HOH 161 463 463 HOH HOH A .
N 4 HOH 162 464 464 HOH HOH A .
N 4 HOH 163 465 465 HOH HOH A .
N 4 HOH 164 466 466 HOH HOH A .
N 4 HOH 165 467 467 HOH HOH A .
N 4 HOH 166 468 468 HOH HOH A .
N 4 HOH 167 469 469 HOH HOH A .
N 4 HOH 168 470 470 HOH HOH A .
N 4 HOH 169 471 471 HOH HOH A .
N 4 HOH 170 472 472 HOH HOH A .
N 4 HOH 171 473 473 HOH HOH A .
N 4 HOH 172 474 474 HOH HOH A .
N 4 HOH 173 475 475 HOH HOH A .
N 4 HOH 174 476 476 HOH HOH A .
N 4 HOH 175 477 477 HOH HOH A .
N 4 HOH 176 478 478 HOH HOH A .
N 4 HOH 177 479 479 HOH HOH A .
N 4 HOH 178 480 480 HOH HOH A .
N 4 HOH 179 481 481 HOH HOH A .
N 4 HOH 180 482 482 HOH HOH A .
N 4 HOH 181 483 483 HOH HOH A .
N 4 HOH 182 484 484 HOH HOH A .
N 4 HOH 183 485 485 HOH HOH A .
N 4 HOH 184 486 486 HOH HOH A .
N 4 HOH 185 487 487 HOH HOH A .
N 4 HOH 186 488 488 HOH HOH A .
N 4 HOH 187 489 489 HOH HOH A .
N 4 HOH 188 490 490 HOH HOH A .
N 4 HOH 189 491 491 HOH HOH A .
N 4 HOH 190 492 492 HOH HOH A .
N 4 HOH 191 493 493 HOH HOH A .
N 4 HOH 192 495 495 HOH HOH A .
N 4 HOH 193 496 496 HOH HOH A .
N 4 HOH 194 497 497 HOH HOH A .
N 4 HOH 195 498 498 HOH HOH A .
N 4 HOH 196 499 499 HOH HOH A .
N 4 HOH 197 500 500 HOH HOH A .
N 4 HOH 198 501 501 HOH HOH A .
N 4 HOH 199 502 502 HOH HOH A .
N 4 HOH 200 503 503 HOH HOH A .
N 4 HOH 201 504 504 HOH HOH A .
N 4 HOH 202 505 505 HOH HOH A .
N 4 HOH 203 506 506 HOH HOH A .
N 4 HOH 204 507 507 HOH HOH A .
N 4 HOH 205 508 508 HOH HOH A .
N 4 HOH 206 509 509 HOH HOH A .
N 4 HOH 207 510 510 HOH HOH A .
N 4 HOH 208 511 511 HOH HOH A .
N 4 HOH 209 512 512 HOH HOH A .
N 4 HOH 210 513 513 HOH HOH A .
N 4 HOH 211 514 514 HOH HOH A .
N 4 HOH 212 515 515 HOH HOH A .
N 4 HOH 213 516 516 HOH HOH A .
N 4 HOH 214 517 517 HOH HOH A .
N 4 HOH 215 518 518 HOH HOH A .
N 4 HOH 216 519 519 HOH HOH A .
N 4 HOH 217 520 520 HOH HOH A .
N 4 HOH 218 521 521 HOH HOH A .
N 4 HOH 219 522 522 HOH HOH A .
N 4 HOH 220 523 523 HOH HOH A .
N 4 HOH 221 524 524 HOH HOH A .
N 4 HOH 222 526 526 HOH HOH A .
N 4 HOH 223 527 527 HOH HOH A .
N 4 HOH 224 528 528 HOH HOH A .
N 4 HOH 225 529 529 HOH HOH A .
N 4 HOH 226 530 530 HOH HOH A .
N 4 HOH 227 531 531 HOH HOH A .
N 4 HOH 228 532 532 HOH HOH A .
N 4 HOH 229 533 533 HOH HOH A .
N 4 HOH 230 534 534 HOH HOH A .
N 4 HOH 231 535 535 HOH HOH A .
N 4 HOH 232 536 536 HOH HOH A .
N 4 HOH 233 537 537 HOH HOH A .
N 4 HOH 234 538 538 HOH HOH A .
N 4 HOH 235 539 539 HOH HOH A .
N 4 HOH 236 540 540 HOH HOH A .
N 4 HOH 237 541 541 HOH HOH A .
N 4 HOH 238 542 542 HOH HOH A .
N 4 HOH 239 543 543 HOH HOH A .
N 4 HOH 240 544 544 HOH HOH A .
N 4 HOH 241 545 545 HOH HOH A .
N 4 HOH 242 546 546 HOH HOH A .
N 4 HOH 243 547 547 HOH HOH A .
N 4 HOH 244 548 548 HOH HOH A .
N 4 HOH 245 549 549 HOH HOH A .
N 4 HOH 246 550 550 HOH HOH A .
N 4 HOH 247 551 551 HOH HOH A .
N 4 HOH 248 552 552 HOH HOH A .
N 4 HOH 249 553 553 HOH HOH A .
N 4 HOH 250 554 554 HOH HOH A .
N 4 HOH 251 555 555 HOH HOH A .
N 4 HOH 252 556 556 HOH HOH A .
N 4 HOH 253 557 557 HOH HOH A .
N 4 HOH 254 558 558 HOH HOH A .
N 4 HOH 255 559 559 HOH HOH A .
N 4 HOH 256 560 560 HOH HOH A .
N 4 HOH 257 561 561 HOH HOH A .
N 4 HOH 258 562 562 HOH HOH A .
N 4 HOH 259 563 563 HOH HOH A .
N 4 HOH 260 564 564 HOH HOH A .
N 4 HOH 261 565 565 HOH HOH A .
N 4 HOH 262 566 566 HOH HOH A .
N 4 HOH 263 567 567 HOH HOH A .
N 4 HOH 264 568 568 HOH HOH A .
N 4 HOH 265 569 569 HOH HOH A .
N 4 HOH 266 570 570 HOH HOH A .
N 4 HOH 267 571 571 HOH HOH A .
N 4 HOH 268 572 572 HOH HOH A .
N 4 HOH 269 573 573 HOH HOH A .
N 4 HOH 270 574 574 HOH HOH A .
N 4 HOH 271 575 575 HOH HOH A .
N 4 HOH 272 576 576 HOH HOH A .
N 4 HOH 273 577 577 HOH HOH A .
N 4 HOH 274 578 578 HOH HOH A .
N 4 HOH 275 579 579 HOH HOH A .
N 4 HOH 276 580 580 HOH HOH A .
N 4 HOH 277 581 581 HOH HOH A .
N 4 HOH 278 582 582 HOH HOH A .
N 4 HOH 279 583 583 HOH HOH A .
N 4 HOH 280 584 584 HOH HOH A .
N 4 HOH 281 585 585 HOH HOH A .
N 4 HOH 282 586 586 HOH HOH A .
N 4 HOH 283 587 587 HOH HOH A .
N 4 HOH 284 588 588 HOH HOH A .
N 4 HOH 285 589 589 HOH HOH A .
N 4 HOH 286 590 590 HOH HOH A .
N 4 HOH 287 591 591 HOH HOH A .
N 4 HOH 288 592 592 HOH HOH A .
N 4 HOH 289 593 593 HOH HOH A .
N 4 HOH 290 594 594 HOH HOH A .
N 4 HOH 291 595 595 HOH HOH A .
N 4 HOH 292 596 596 HOH HOH A .
N 4 HOH 293 597 597 HOH HOH A .
N 4 HOH 294 598 598 HOH HOH A .
N 4 HOH 295 599 599 HOH HOH A .
N 4 HOH 296 600 600 HOH HOH A .
N 4 HOH 297 601 601 HOH HOH A .
N 4 HOH 298 602 602 HOH HOH A .
N 4 HOH 299 603 603 HOH HOH A .
N 4 HOH 300 604 604 HOH HOH A .
N 4 HOH 301 605 605 HOH HOH A .
N 4 HOH 302 606 606 HOH HOH A .
N 4 HOH 303 607 607 HOH HOH A .
N 4 HOH 304 608 608 HOH HOH A .
N 4 HOH 305 609 609 HOH HOH A .
N 4 HOH 306 610 610 HOH HOH A .
N 4 HOH 307 611 611 HOH HOH A .
N 4 HOH 308 612 612 HOH HOH A .
N 4 HOH 309 613 613 HOH HOH A .
N 4 HOH 310 614 614 HOH HOH A .
N 4 HOH 311 615 615 HOH HOH A .
N 4 HOH 312 616 616 HOH HOH A .
N 4 HOH 313 617 617 HOH HOH A .
N 4 HOH 314 618 618 HOH HOH A .
N 4 HOH 315 619 619 HOH HOH A .
N 4 HOH 316 620 620 HOH HOH A .
N 4 HOH 317 621 621 HOH HOH A .
N 4 HOH 318 622 622 HOH HOH A .
N 4 HOH 319 623 623 HOH HOH A .
N 4 HOH 320 624 624 HOH HOH A .
N 4 HOH 321 625 625 HOH HOH A .
N 4 HOH 322 626 626 HOH HOH A .
N 4 HOH 323 627 627 HOH HOH A .
N 4 HOH 324 628 628 HOH HOH A .
N 4 HOH 325 629 629 HOH HOH A .
N 4 HOH 326 630 630 HOH HOH A .
N 4 HOH 327 631 631 HOH HOH A .
N 4 HOH 328 632 632 HOH HOH A .
N 4 HOH 329 633 633 HOH HOH A .
N 4 HOH 330 634 634 HOH HOH A .
N 4 HOH 331 635 635 HOH HOH A .
N 4 HOH 332 636 636 HOH HOH A .
N 4 HOH 333 637 637 HOH HOH A .
N 4 HOH 334 638 638 HOH HOH A .
N 4 HOH 335 639 639 HOH HOH A .
N 4 HOH 336 640 640 HOH HOH A .
N 4 HOH 337 641 641 HOH HOH A .
N 4 HOH 338 642 642 HOH HOH A .
N 4 HOH 339 643 643 HOH HOH A .
N 4 HOH 340 644 644 HOH HOH A .
N 4 HOH 341 645 645 HOH HOH A .
N 4 HOH 342 646 646 HOH HOH A .
N 4 HOH 343 647 647 HOH HOH A .
N 4 HOH 344 648 648 HOH HOH A .
N 4 HOH 345 649 649 HOH HOH A .
N 4 HOH 346 650 650 HOH HOH A .
N 4 HOH 347 651 651 HOH HOH A .
N 4 HOH 348 652 652 HOH HOH A .
N 4 HOH 349 653 653 HOH HOH A .
N 4 HOH 350 654 654 HOH HOH A .
N 4 HOH 351 655 655 HOH HOH A .
N 4 HOH 352 656 656 HOH HOH A .
N 4 HOH 353 657 657 HOH HOH A .
N 4 HOH 354 658 658 HOH HOH A .
N 4 HOH 355 659 659 HOH HOH A .
N 4 HOH 356 660 660 HOH HOH A .
N 4 HOH 357 661 661 HOH HOH A .
N 4 HOH 358 662 662 HOH HOH A .
N 4 HOH 359 663 663 HOH HOH A .
N 4 HOH 360 664 664 HOH HOH A .
N 4 HOH 361 665 665 HOH HOH A .
N 4 HOH 362 666 666 HOH HOH A .
N 4 HOH 363 667 667 HOH HOH A .
N 4 HOH 364 668 668 HOH HOH A .
N 4 HOH 365 669 669 HOH HOH A .
N 4 HOH 366 670 670 HOH HOH A .
N 4 HOH 367 671 671 HOH HOH A .
N 4 HOH 368 672 672 HOH HOH A .
N 4 HOH 369 673 673 HOH HOH A .
N 4 HOH 370 674 674 HOH HOH A .
N 4 HOH 371 675 675 HOH HOH A .
N 4 HOH 372 676 676 HOH HOH A .
N 4 HOH 373 677 677 HOH HOH A .
N 4 HOH 374 678 678 HOH HOH A .
N 4 HOH 375 679 679 HOH HOH A .
N 4 HOH 376 680 680 HOH HOH A .
N 4 HOH 377 681 681 HOH HOH A .
N 4 HOH 378 683 683 HOH HOH A .
N 4 HOH 379 684 684 HOH HOH A .
N 4 HOH 380 685 685 HOH HOH A .
N 4 HOH 381 686 686 HOH HOH A .
N 4 HOH 382 687 687 HOH HOH A .
N 4 HOH 383 688 688 HOH HOH A .
N 4 HOH 384 689 689 HOH HOH A .
N 4 HOH 385 690 690 HOH HOH A .
N 4 HOH 386 691 691 HOH HOH A .
N 4 HOH 387 692 692 HOH HOH A .
N 4 HOH 388 693 693 HOH HOH A .
N 4 HOH 389 694 694 HOH HOH A .
N 4 HOH 390 695 695 HOH HOH A .
N 4 HOH 391 696 696 HOH HOH A .
N 4 HOH 392 697 697 HOH HOH A .
N 4 HOH 393 698 698 HOH HOH A .
N 4 HOH 394 699 699 HOH HOH A .
N 4 HOH 395 700 700 HOH HOH A .
N 4 HOH 396 701 701 HOH HOH A .
N 4 HOH 397 702 702 HOH HOH A .
N 4 HOH 398 703 703 HOH HOH A .
N 4 HOH 399 704 704 HOH HOH A .
N 4 HOH 400 705 705 HOH HOH A .
N 4 HOH 401 706 706 HOH HOH A .
N 4 HOH 402 707 707 HOH HOH A .
N 4 HOH 403 708 708 HOH HOH A .
N 4 HOH 404 709 709 HOH HOH A .
N 4 HOH 405 710 710 HOH HOH A .
N 4 HOH 406 711 711 HOH HOH A .
N 4 HOH 407 712 712 HOH HOH A .
N 4 HOH 408 713 713 HOH HOH A .
N 4 HOH 409 714 714 HOH HOH A .
N 4 HOH 410 715 715 HOH HOH A .
N 4 HOH 411 716 716 HOH HOH A .
N 4 HOH 412 717 717 HOH HOH A .
N 4 HOH 413 718 718 HOH HOH A .
N 4 HOH 414 719 719 HOH HOH A .
N 4 HOH 415 720 720 HOH HOH A .
N 4 HOH 416 721 721 HOH HOH A .
N 4 HOH 417 722 722 HOH HOH A .
N 4 HOH 418 723 723 HOH HOH A .
N 4 HOH 419 724 724 HOH HOH A .
N 4 HOH 420 725 725 HOH HOH A .
N 4 HOH 421 726 726 HOH HOH A .
N 4 HOH 422 727 727 HOH HOH A .
N 4 HOH 423 728 728 HOH HOH A .
N 4 HOH 424 729 729 HOH HOH A .
N 4 HOH 425 730 730 HOH HOH A .
N 4 HOH 426 731 731 HOH HOH A .
N 4 HOH 427 732 732 HOH HOH A .
N 4 HOH 428 733 733 HOH HOH A .
N 4 HOH 429 734 734 HOH HOH A .
N 4 HOH 430 735 735 HOH HOH A .
N 4 HOH 431 736 736 HOH HOH A .
N 4 HOH 432 737 737 HOH HOH A .
N 4 HOH 433 738 738 HOH HOH A .
N 4 HOH 434 739 739 HOH HOH A .
N 4 HOH 435 740 740 HOH HOH A .
N 4 HOH 436 741 741 HOH HOH A .
N 4 HOH 437 742 742 HOH HOH A .
N 4 HOH 438 743 743 HOH HOH A .
N 4 HOH 439 744 744 HOH HOH A .
N 4 HOH 440 745 745 HOH HOH A .
N 4 HOH 441 746 746 HOH HOH A .
N 4 HOH 442 747 747 HOH HOH A .
N 4 HOH 443 748 748 HOH HOH A .
N 4 HOH 444 749 749 HOH HOH A .
N 4 HOH 445 750 750 HOH HOH A .
N 4 HOH 446 751 751 HOH HOH A .
N 4 HOH 447 752 752 HOH HOH A .
N 4 HOH 448 753 753 HOH HOH A .
N 4 HOH 449 754 754 HOH HOH A .
N 4 HOH 450 755 755 HOH HOH A .
N 4 HOH 451 756 756 HOH HOH A .
N 4 HOH 452 757 757 HOH HOH A .
N 4 HOH 453 758 758 HOH HOH A .
N 4 HOH 454 759 759 HOH HOH A .
N 4 HOH 455 760 760 HOH HOH A .
N 4 HOH 456 761 761 HOH HOH A .
N 4 HOH 457 762 762 HOH HOH A .
N 4 HOH 458 763 763 HOH HOH A .
N 4 HOH 459 764 764 HOH HOH A .
N 4 HOH 460 765 765 HOH HOH A .
N 4 HOH 461 766 766 HOH HOH A .
N 4 HOH 462 767 767 HOH HOH A .
N 4 HOH 463 768 768 HOH HOH A .
N 4 HOH 464 769 769 HOH HOH A .
N 4 HOH 465 770 770 HOH HOH A .
N 4 HOH 466 771 771 HOH HOH A .
N 4 HOH 467 772 772 HOH HOH A .
N 4 HOH 468 773 773 HOH HOH A .
N 4 HOH 469 774 774 HOH HOH A .
N 4 HOH 470 775 775 HOH HOH A .
N 4 HOH 471 776 776 HOH HOH A .
N 4 HOH 472 777 777 HOH HOH A .
N 4 HOH 473 778 778 HOH HOH A .
N 4 HOH 474 779 779 HOH HOH A .
N 4 HOH 475 780 780 HOH HOH A .
N 4 HOH 476 781 781 HOH HOH A .
N 4 HOH 477 782 782 HOH HOH A .
N 4 HOH 478 783 783 HOH HOH A .
N 4 HOH 479 784 784 HOH HOH A .
N 4 HOH 480 785 785 HOH HOH A .
N 4 HOH 481 786 786 HOH HOH A .
N 4 HOH 482 787 787 HOH HOH A .
N 4 HOH 483 788 788 HOH HOH A .
N 4 HOH 484 789 789 HOH HOH A .
N 4 HOH 485 790 790 HOH HOH A .
N 4 HOH 486 791 791 HOH HOH A .
N 4 HOH 487 792 792 HOH HOH A .
N 4 HOH 488 793 793 HOH HOH A .
N 4 HOH 489 794 794 HOH HOH A .
N 4 HOH 490 795 795 HOH HOH A .
N 4 HOH 491 796 796 HOH HOH A .
N 4 HOH 492 797 797 HOH HOH A .
N 4 HOH 493 798 798 HOH HOH A .
N 4 HOH 494 799 799 HOH HOH A .
N 4 HOH 495 800 800 HOH HOH A .
N 4 HOH 496 801 801 HOH HOH A .
N 4 HOH 497 802 802 HOH HOH A .
N 4 HOH 498 803 803 HOH HOH A .
N 4 HOH 499 804 804 HOH HOH A .
N 4 HOH 500 805 805 HOH HOH A .
N 4 HOH 501 806 806 HOH HOH A .
N 4 HOH 502 807 807 HOH HOH A .
N 4 HOH 503 808 808 HOH HOH A .
N 4 HOH 504 809 809 HOH HOH A .
N 4 HOH 505 810 810 HOH HOH A .
N 4 HOH 506 811 811 HOH HOH A .
N 4 HOH 507 812 812 HOH HOH A .
N 4 HOH 508 813 813 HOH HOH A .
N 4 HOH 509 814 814 HOH HOH A .
N 4 HOH 510 815 815 HOH HOH A .
N 4 HOH 511 816 816 HOH HOH A .
N 4 HOH 512 817 817 HOH HOH A .
N 4 HOH 513 818 818 HOH HOH A .
N 4 HOH 514 819 819 HOH HOH A .
N 4 HOH 515 820 820 HOH HOH A .
N 4 HOH 516 821 821 HOH HOH A .
N 4 HOH 517 822 822 HOH HOH A .
N 4 HOH 518 823 823 HOH HOH A .
N 4 HOH 519 824 824 HOH HOH A .
N 4 HOH 520 825 825 HOH HOH A .
N 4 HOH 521 826 826 HOH HOH A .
N 4 HOH 522 827 827 HOH HOH A .
N 4 HOH 523 828 828 HOH HOH A .
N 4 HOH 524 829 829 HOH HOH A .
N 4 HOH 525 830 830 HOH HOH A .
N 4 HOH 526 831 831 HOH HOH A .
N 4 HOH 527 832 832 HOH HOH A .
N 4 HOH 528 833 833 HOH HOH A .
N 4 HOH 529 834 834 HOH HOH A .
N 4 HOH 530 835 835 HOH HOH A .
N 4 HOH 531 836 836 HOH HOH A .
N 4 HOH 532 837 837 HOH HOH A .
N 4 HOH 533 838 838 HOH HOH A .
N 4 HOH 534 839 839 HOH HOH A .
N 4 HOH 535 840 840 HOH HOH A .
N 4 HOH 536 841 841 HOH HOH A .
N 4 HOH 537 843 843 HOH HOH A .
N 4 HOH 538 844 844 HOH HOH A .
N 4 HOH 539 845 845 HOH HOH A .
N 4 HOH 540 846 846 HOH HOH A .
N 4 HOH 541 847 847 HOH HOH A .
N 4 HOH 542 848 848 HOH HOH A .
N 4 HOH 543 849 849 HOH HOH A .
N 4 HOH 544 850 850 HOH HOH A .
N 4 HOH 545 851 851 HOH HOH A .
N 4 HOH 546 852 852 HOH HOH A .
N 4 HOH 547 854 854 HOH HOH A .
N 4 HOH 548 855 855 HOH HOH A .
N 4 HOH 549 856 856 HOH HOH A .
N 4 HOH 550 857 857 HOH HOH A .
N 4 HOH 551 858 858 HOH HOH A .
N 4 HOH 552 859 859 HOH HOH A .
N 4 HOH 553 860 860 HOH HOH A .
N 4 HOH 554 861 861 HOH HOH A .
N 4 HOH 555 862 862 HOH HOH A .
N 4 HOH 556 863 863 HOH HOH A .
N 4 HOH 557 864 864 HOH HOH A .
N 4 HOH 558 865 865 HOH HOH A .
N 4 HOH 559 866 866 HOH HOH A .
N 4 HOH 560 867 867 HOH HOH A .
N 4 HOH 561 868 868 HOH HOH A .
N 4 HOH 562 869 869 HOH HOH A .
N 4 HOH 563 870 870 HOH HOH A .
N 4 HOH 564 871 871 HOH HOH A .
N 4 HOH 565 872 872 HOH HOH A .
N 4 HOH 566 873 873 HOH HOH A .
N 4 HOH 567 874 874 HOH HOH A .
N 4 HOH 568 875 875 HOH HOH A .
N 4 HOH 569 876 876 HOH HOH A .
N 4 HOH 570 877 877 HOH HOH A .
N 4 HOH 571 878 878 HOH HOH A .
N 4 HOH 572 879 879 HOH HOH A .
N 4 HOH 573 880 880 HOH HOH A .
N 4 HOH 574 881 881 HOH HOH A .
N 4 HOH 575 882 882 HOH HOH A .
N 4 HOH 576 883 883 HOH HOH A .
N 4 HOH 577 884 884 HOH HOH A .
N 4 HOH 578 885 885 HOH HOH A .
N 4 HOH 579 886 886 HOH HOH A .
N 4 HOH 580 887 887 HOH HOH A .
N 4 HOH 581 888 888 HOH HOH A .
N 4 HOH 582 889 889 HOH HOH A .
N 4 HOH 583 890 890 HOH HOH A .
N 4 HOH 584 891 891 HOH HOH A .
N 4 HOH 585 892 892 HOH HOH A .
N 4 HOH 586 893 893 HOH HOH A .
N 4 HOH 587 894 894 HOH HOH A .
N 4 HOH 588 895 895 HOH HOH A .
N 4 HOH 589 896 896 HOH HOH A .
N 4 HOH 590 897 897 HOH HOH A .
N 4 HOH 591 898 898 HOH HOH A .
N 4 HOH 592 899 899 HOH HOH A .
N 4 HOH 593 900 900 HOH HOH A .
N 4 HOH 594 901 901 HOH HOH A .
N 4 HOH 595 902 902 HOH HOH A .
N 4 HOH 596 903 903 HOH HOH A .
N 4 HOH 597 904 904 HOH HOH A .
N 4 HOH 598 905 905 HOH HOH A .
N 4 HOH 599 906 906 HOH HOH A .
N 4 HOH 600 907 907 HOH HOH A .
N 4 HOH 601 908 908 HOH HOH A .
N 4 HOH 602 909 909 HOH HOH A .
N 4 HOH 603 910 910 HOH HOH A .
N 4 HOH 604 911 911 HOH HOH A .
N 4 HOH 605 912 912 HOH HOH A .
N 4 HOH 606 913 913 HOH HOH A .
N 4 HOH 607 914 914 HOH HOH A .
N 4 HOH 608 915 915 HOH HOH A .
N 4 HOH 609 916 916 HOH HOH A .
N 4 HOH 610 917 917 HOH HOH A .
N 4 HOH 611 920 920 HOH HOH A .
N 4 HOH 612 921 921 HOH HOH A .
N 4 HOH 613 922 922 HOH HOH A .
N 4 HOH 614 923 923 HOH HOH A .
N 4 HOH 615 924 924 HOH HOH A .
N 4 HOH 616 925 925 HOH HOH A .
N 4 HOH 617 926 926 HOH HOH A .
N 4 HOH 618 927 927 HOH HOH A .
N 4 HOH 619 928 928 HOH HOH A .
N 4 HOH 620 929 929 HOH HOH A .
N 4 HOH 621 930 930 HOH HOH A .
O 4 HOH 1 412 412 HOH HOH B .
O 4 HOH 2 413 413 HOH HOH B .
O 4 HOH 3 494 494 HOH HOH B .
O 4 HOH 4 525 525 HOH HOH B .
O 4 HOH 5 682 682 HOH HOH B .
O 4 HOH 6 842 842 HOH HOH B .
O 4 HOH 7 853 853 HOH HOH B .
O 4 HOH 8 918 918 HOH HOH B .
O 4 HOH 9 919 919 HOH HOH B .
#
loop_
_software.name
_software.classification
_software.version
_software.citation_id
_software.pdbx_ordinal
DENZO 'data reduction' . ? 1
SCALEPACK 'data scaling' . ? 2
AMoRE phasing . ? 3
CNS refinement 1.0 ? 4
#
_cell.entry_id 1KUG
_cell.length_a 61.151
_cell.length_b 61.151
_cell.length_c 131.193
_cell.angle_alpha 90.00
_cell.angle_beta 90.00
_cell.angle_gamma 90.00
_cell.Z_PDB 8
_cell.pdbx_unique_axis ?
_cell.length_a_esd ?
_cell.length_b_esd ?
_cell.length_c_esd ?
_cell.angle_alpha_esd ?
_cell.angle_beta_esd ?
_cell.angle_gamma_esd ?
#
_symmetry.entry_id 1KUG
_symmetry.space_group_name_H-M 'P 41 21 2'
_symmetry.pdbx_full_space_group_name_H-M ?
_symmetry.cell_setting ?
_symmetry.Int_Tables_number 92
_symmetry.space_group_name_Hall ?
#
_exptl.entry_id 1KUG
_exptl.method 'X-ray diffraction'
_exptl.crystals_number 5
#
_exptl_crystal.id 1
_exptl_crystal.density_meas ?
_exptl_crystal.density_percent_sol 52.23
_exptl_crystal.density_Matthews 2.57
_exptl_crystal.description ?
_exptl_crystal.F_000 ?
_exptl_crystal.preparation ?
#
_exptl_crystal_grow.crystal_id 1
_exptl_crystal_grow.method 'VAPOR DIFFUSION, HANGING DROP'
_exptl_crystal_grow.temp 277.0
_exptl_crystal_grow.temp_details ?
_exptl_crystal_grow.pH 4.6
_exptl_crystal_grow.pdbx_details
'PEG400, sodium acetate, cadmium chloride, pH 4.6, VAPOR DIFFUSION, HANGING DROP, temperature 277.0K'
_exptl_crystal_grow.pdbx_pH_range ?
#
_diffrn.id 1
_diffrn.ambient_temp 123
_diffrn.ambient_temp_details ?
_diffrn.crystal_id 1
#
_diffrn_detector.diffrn_id 1
_diffrn_detector.detector 'Image plate'
_diffrn_detector.type RIGAKU
_diffrn_detector.pdbx_collection_date 2000-12-21
_diffrn_detector.details ?
#
_diffrn_radiation.diffrn_id 1
_diffrn_radiation.wavelength_id 1
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l M
_diffrn_radiation.monochromator ?
_diffrn_radiation.pdbx_diffrn_protocol 'Single wavelength'
_diffrn_radiation.pdbx_scattering_type x-ray
#
_diffrn_radiation_wavelength.id 1
_diffrn_radiation_wavelength.wavelength 1.08
_diffrn_radiation_wavelength.wt 1.0
#
_diffrn_source.diffrn_id 1
_diffrn_source.source Synchrotron
_diffrn_source.type 'NSRRC BEAMLINE BL17B2'
_diffrn_source.pdbx_synchrotron_site NSRRC
_diffrn_source.pdbx_synchrotron_beamline BL17B2
_diffrn_source.pdbx_wavelength ?
_diffrn_source.pdbx_wavelength_list 1.08
#
_reflns.entry_id 1KUG
_reflns.observed_criterion_sigma_I 2.0
_reflns.observed_criterion_sigma_F 2.0
_reflns.d_resolution_low 30
_reflns.d_resolution_high 1.37
_reflns.number_obs 49996
_reflns.number_all 121022
_reflns.percent_possible_obs 93.9
_reflns.pdbx_Rmerge_I_obs 0.06
_reflns.pdbx_Rsym_value ?
_reflns.pdbx_netI_over_sigmaI 15.9
_reflns.B_iso_Wilson_estimate ?
_reflns.pdbx_redundancy 2.4
_reflns.R_free_details ?
_reflns.limit_h_max ?
_reflns.limit_h_min ?
_reflns.limit_k_max ?
_reflns.limit_k_min ?
_reflns.limit_l_max ?
_reflns.limit_l_min ?
_reflns.observed_criterion_F_max ?
_reflns.observed_criterion_F_min ?
_reflns.pdbx_chi_squared ?
_reflns.pdbx_scaling_rejects ?
_reflns.pdbx_ordinal 1
_reflns.pdbx_diffrn_id 1
#
_reflns_shell.d_res_high 1.37
_reflns_shell.d_res_low 1.42
_reflns_shell.percent_possible_all 88.1
_reflns_shell.Rmerge_I_obs 0.333
_reflns_shell.pdbx_Rsym_value ?
_reflns_shell.meanI_over_sigI_obs 2.4
_reflns_shell.pdbx_redundancy ?
_reflns_shell.percent_possible_obs ?
_reflns_shell.number_unique_all 4604
_reflns_shell.number_measured_all ?
_reflns_shell.number_measured_obs ?
_reflns_shell.number_unique_obs ?
_reflns_shell.pdbx_chi_squared ?
_reflns_shell.pdbx_ordinal 1
_reflns_shell.pdbx_diffrn_id 1
#
_refine.entry_id 1KUG
_refine.ls_number_reflns_obs 45671
_refine.ls_number_reflns_all 48075
_refine.pdbx_ls_sigma_I ?
_refine.pdbx_ls_sigma_F 2.0
_refine.pdbx_data_cutoff_high_absF ?
_refine.pdbx_data_cutoff_low_absF ?
_refine.ls_d_res_low 30.0
_refine.ls_d_res_high 1.37
_refine.ls_percent_reflns_obs ?
_refine.ls_R_factor_obs ?
_refine.ls_R_factor_all ?
_refine.ls_R_factor_R_work 0.172
_refine.ls_R_factor_R_free 0.202
_refine.ls_R_factor_R_free_error ?
_refine.ls_R_factor_R_free_error_details ?
_refine.ls_percent_reflns_R_free ?
_refine.ls_number_reflns_R_free 2404
_refine.ls_number_parameters ?
_refine.ls_number_restraints ?
_refine.occupancy_min ?
_refine.occupancy_max ?
_refine.B_iso_mean ?
_refine.aniso_B[1][1] ?
_refine.aniso_B[2][2] ?
_refine.aniso_B[3][3] ?
_refine.aniso_B[1][2] ?
_refine.aniso_B[1][3] ?
_refine.aniso_B[2][3] ?
_refine.solvent_model_details ?
_refine.solvent_model_param_ksol ?
_refine.solvent_model_param_bsol ?
_refine.pdbx_ls_cross_valid_method ?
_refine.details ?
_refine.pdbx_starting_model ?
_refine.pdbx_method_to_determine_struct 'MOLECULAR REPLACEMENT'
_refine.pdbx_isotropic_thermal_model ?
_refine.pdbx_stereochemistry_target_values 'Engh & Huber'
_refine.pdbx_stereochem_target_val_spec_case ?
_refine.pdbx_R_Free_selection_details random
_refine.pdbx_overall_ESU_R_Free ?
_refine.overall_SU_B ?
_refine.ls_redundancy_reflns_obs ?
_refine.B_iso_min ?
_refine.B_iso_max ?
_refine.correlation_coeff_Fo_to_Fc ?
_refine.overall_SU_R_Cruickshank_DPI ?
_refine.overall_SU_R_free ?
_refine.overall_SU_ML ?
_refine.pdbx_data_cutoff_high_rms_absF ?
_refine.correlation_coeff_Fo_to_Fc_free ?
_refine.pdbx_solvent_vdw_probe_radii ?
_refine.pdbx_solvent_ion_probe_radii ?
_refine.pdbx_solvent_shrinkage_radii ?
_refine.pdbx_refine_id 'X-ray diffraction'
_refine.pdbx_overall_ESU_R ?
_refine.pdbx_overall_phase_error ?
_refine.ls_wR_factor_R_free ?
_refine.ls_wR_factor_R_work ?
_refine.overall_FOM_free_R_set ?
_refine.overall_FOM_work_R_set ?
_refine.pdbx_diffrn_id 1
_refine.pdbx_TLS_residual_ADP_flag ?
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI ?
_refine.pdbx_overall_SU_R_Blow_DPI ?
_refine.pdbx_overall_SU_R_free_Blow_DPI ?
#
_refine_hist.pdbx_refine_id 'X-ray diffraction'
_refine_hist.cycle_id LAST
_refine_hist.pdbx_number_atoms_protein 1646
_refine_hist.pdbx_number_atoms_nucleic_acid 0
_refine_hist.pdbx_number_atoms_ligand 11
_refine_hist.number_atoms_solvent 630
_refine_hist.number_atoms_total 2287
_refine_hist.d_res_high 1.37
_refine_hist.d_res_low 30.0
#
loop_
_refine_ls_restr.type
_refine_ls_restr.dev_ideal
_refine_ls_restr.dev_ideal_target
_refine_ls_restr.weight
_refine_ls_restr.number
_refine_ls_restr.pdbx_refine_id
_refine_ls_restr.pdbx_restraint_function
'c_bond_d' 0.015 ? ? ? 'X-ray diffraction' ?
'c_angle_deg' 1.66 ? ? ? 'X-ray diffraction' ?
#
_struct.entry_id 1KUG
_struct.title 'Crystal Structure of a Taiwan Habu Venom Metalloproteinase complexed with its endogenous inhibitor pENW'
_struct.pdbx_model_details ?
_struct.pdbx_CASP_flag ?
_struct.pdbx_model_type_details ?
#
_struct_keywords.entry_id 1KUG
_struct_keywords.pdbx_keywords 'HYDROLASE/HYDROLASE INHIBITOR'
_struct_keywords.text 'alpha/beta protein, retro-binding manner, HYDROLASE-HYDROLASE INHIBITOR COMPLEX'
#
loop_
_struct_asym.id
_struct_asym.pdbx_blank_PDB_chainid_flag
_struct_asym.pdbx_modified
_struct_asym.entity_id
_struct_asym.details
A N N 1 ?
B N N 2 ?
C N N 3 ?
D N N 3 ?
E N N 3 ?
F N N 3 ?
G N N 3 ?
H N N 3 ?
I N N 3 ?
J N N 3 ?
K N N 3 ?
L N N 3 ?
M N N 3 ?
N N N 4 ?
O N N 4 ?
#
loop_
_struct_ref.entity_id
_struct_ref.pdbx_db_accession
_struct_ref.db_code
_struct_ref.db_name
_struct_ref.id
_struct_ref.pdbx_align_begin
_struct_ref.pdbx_seq_one_letter_code
_struct_ref.pdbx_db_isoform
1 O57413 O57413_TRIMU UNP 1 196
;EQQRFPQRYIELAIVVDHGMHTKYSSNFKKIRKRVHQMVSNMNEMCRPLNIAITLALLDVWSEKDFITVQADAPTTAGLF
GDWRERVLLKKKNHDHAQLLTDTNFARNTIGWAYVGRMCDEKYSVAVVKDHSSKVFMVAVTMTHELGHNLGMEHDDKDKC
KCDTCIMSPVISDKQSKLFSDCSKDYYQTFLTNDNPQCILNAP
;
?
2 1KUG 1KUG PDB 2 1 ENW ?
#
loop_
_struct_ref_seq.align_id
_struct_ref_seq.ref_id
_struct_ref_seq.pdbx_PDB_id_code
_struct_ref_seq.pdbx_strand_id
_struct_ref_seq.seq_align_beg
_struct_ref_seq.pdbx_seq_align_beg_ins_code
_struct_ref_seq.seq_align_end
_struct_ref_seq.pdbx_seq_align_end_ins_code
_struct_ref_seq.pdbx_db_accession
_struct_ref_seq.db_align_beg
_struct_ref_seq.pdbx_db_align_beg_ins_code
_struct_ref_seq.db_align_end
_struct_ref_seq.pdbx_db_align_end_ins_code
_struct_ref_seq.pdbx_auth_seq_align_beg
_struct_ref_seq.pdbx_auth_seq_align_end
1 1 1KUG A 1 ? 203 ? O57413 196 ? 398 ? 1 203
2 2 1KUG B 1 ? 3 ? 1KUG 251 ? 253 ? 251 253
#
loop_
_struct_ref_seq_dif.align_id
_struct_ref_seq_dif.pdbx_pdb_id_code
_struct_ref_seq_dif.mon_id
_struct_ref_seq_dif.pdbx_pdb_strand_id
_struct_ref_seq_dif.seq_num
_struct_ref_seq_dif.pdbx_pdb_ins_code
_struct_ref_seq_dif.pdbx_seq_db_name
_struct_ref_seq_dif.pdbx_seq_db_accession_code
_struct_ref_seq_dif.db_mon_id
_struct_ref_seq_dif.pdbx_seq_db_seq_num
_struct_ref_seq_dif.details
_struct_ref_seq_dif.pdbx_auth_seq_num
_struct_ref_seq_dif.pdbx_ordinal
1 1KUG TYR A 21 ? UNP O57413 HIS 216 Conflict 21 1
1 1KUG ILE A 42 ? UNP O57413 MET 237 Conflict 42 2
1 1KUG THR A 163 ? UNP O57413 ASP 358 Conflict 163 3
1 1KUG ALA A 169 ? UNP O57413 PRO 364 Conflict 169 4
#
loop_
_pdbx_struct_assembly.id
_pdbx_struct_assembly.details
_pdbx_struct_assembly.method_details
_pdbx_struct_assembly.oligomeric_details
_pdbx_struct_assembly.oligomeric_count
1 author_and_software_defined_assembly PISA dimeric 2
2 software_defined_assembly PISA tetrameric 4
#
loop_
_pdbx_struct_assembly_prop.biol_id
_pdbx_struct_assembly_prop.type
_pdbx_struct_assembly_prop.value
_pdbx_struct_assembly_prop.details
1 'ABSA (A^2)' 1590 ?
1 MORE -45 ?
1 'SSA (A^2)' 9220 ?
2 'ABSA (A^2)' 3770 ?
2 MORE -116 ?
2 'SSA (A^2)' 18180 ?
#
loop_
_pdbx_struct_assembly_gen.assembly_id
_pdbx_struct_assembly_gen.oper_expression
_pdbx_struct_assembly_gen.asym_id_list
1 1 A,B,C,D,E,F,G,H,I,J,K,L,M,N,O
2 1,2 A,B,C,D,E,F,G,H,I,J,K,L,M,N,O
#
loop_
_pdbx_struct_oper_list.id
_pdbx_struct_oper_list.type
_pdbx_struct_oper_list.name
_pdbx_struct_oper_list.symmetry_operation
_pdbx_struct_oper_list.matrix[1][1]
_pdbx_struct_oper_list.matrix[1][2]
_pdbx_struct_oper_list.matrix[1][3]
_pdbx_struct_oper_list.vector[1]
_pdbx_struct_oper_list.matrix[2][1]
_pdbx_struct_oper_list.matrix[2][2]
_pdbx_struct_oper_list.matrix[2][3]
_pdbx_struct_oper_list.vector[2]
_pdbx_struct_oper_list.matrix[3][1]
_pdbx_struct_oper_list.matrix[3][2]
_pdbx_struct_oper_list.matrix[3][3]
_pdbx_struct_oper_list.vector[3]
1 'identity operation' 1_555 x,y,z 1.0000000000 0.0000000000 0.0000000000 0.0000000000 0.0000000000 1.0000000000 0.0000000000 0.0000000000 0.0000000000 0.0000000000 1.0000000000 0.0000000000
2 'crystal symmetry operation' 8_555 -y,-x,-z+1/2 0.0000000000 -1.0000000000 0.0000000000 0.0000000000 -1.0000000000 0.0000000000 0.0000000000 0.0000000000 0.0000000000 0.0000000000 -1.0000000000 65.5965000000
#
_struct_biol.id 1
_struct_biol.pdbx_parent_biol_id ?
_struct_biol.details ?
#
loop_
_struct_conf.conf_type_id
_struct_conf.id
_struct_conf.pdbx_PDB_helix_id
_struct_conf.beg_label_comp_id
_struct_conf.beg_label_asym_id
_struct_conf.beg_label_seq_id
_struct_conf.pdbx_beg_PDB_ins_code
_struct_conf.end_label_comp_id
_struct_conf.end_label_asym_id
_struct_conf.end_label_seq_id
_struct_conf.pdbx_end_PDB_ins_code
_struct_conf.beg_auth_comp_id
_struct_conf.beg_auth_asym_id
_struct_conf.beg_auth_seq_id
_struct_conf.end_auth_comp_id
_struct_conf.end_auth_asym_id
_struct_conf.end_auth_seq_id
_struct_conf.pdbx_PDB_helix_class
_struct_conf.details
_struct_conf.pdbx_PDB_helix_length
HELX_P HELX_P1 1 ASP A 17 ? TYR A 24 ? ASP A 17 TYR A 24 1 ? 8
HELX_P HELX_P2 2 ASN A 27 ? ARG A 47 ? ASN A 27 ARG A 47 1 ? 21
HELX_P HELX_P3 3 ASP A 72 ? VAL A 87 ? ASP A 72 VAL A 87 1 ? 16
HELX_P HELX_P4 4 VAL A 87 ? LYS A 92 ? VAL A 87 LYS A 92 1 ? 6
HELX_P HELX_P5 5 PHE A 105 ? THR A 109 ? PHE A 105 THR A 109 5 ? 5
HELX_P HELX_P6 6 LYS A 134 ? LEU A 150 ? LYS A 134 LEU A 150 1 ? 17
HELX_P HELX_P7 7 SER A 180 ? ASP A 194 ? SER A 180 ASP A 194 1 ? 15
HELX_P HELX_P8 8 PRO A 196 ? ASN A 201 ? PRO A 196 ASN A 201 5 ? 6
#
_struct_conf_type.id HELX_P
_struct_conf_type.criteria ?
_struct_conf_type.reference ?
#
loop_
_struct_conn.id
_struct_conn.conn_type_id
_struct_conn.pdbx_leaving_atom_flag
_struct_conn.pdbx_PDB_id
_struct_conn.ptnr1_label_asym_id
_struct_conn.ptnr1_label_comp_id
_struct_conn.ptnr1_label_seq_id
_struct_conn.ptnr1_label_atom_id
_struct_conn.pdbx_ptnr1_label_alt_id
_struct_conn.pdbx_ptnr1_PDB_ins_code
_struct_conn.pdbx_ptnr1_standard_comp_id
_struct_conn.ptnr1_symmetry
_struct_conn.ptnr2_label_asym_id
_struct_conn.ptnr2_label_comp_id
_struct_conn.ptnr2_label_seq_id
_struct_conn.ptnr2_label_atom_id
_struct_conn.pdbx_ptnr2_label_alt_id
_struct_conn.pdbx_ptnr2_PDB_ins_code
_struct_conn.ptnr1_auth_asym_id
_struct_conn.ptnr1_auth_comp_id
_struct_conn.ptnr1_auth_seq_id
_struct_conn.ptnr2_auth_asym_id
_struct_conn.ptnr2_auth_comp_id
_struct_conn.ptnr2_auth_seq_id
_struct_conn.ptnr2_symmetry
_struct_conn.pdbx_ptnr3_label_atom_id
_struct_conn.pdbx_ptnr3_label_seq_id
_struct_conn.pdbx_ptnr3_label_comp_id
_struct_conn.pdbx_ptnr3_label_asym_id
_struct_conn.pdbx_ptnr3_label_alt_id
_struct_conn.pdbx_ptnr3_PDB_ins_code
_struct_conn.details
_struct_conn.pdbx_dist_value
_struct_conn.pdbx_value_order
_struct_conn.pdbx_role
disulf1 disulf ? ? A CYS 119 SG ? ? ? 1_555 A CYS 198 SG ? ? A CYS 119 A CYS 198 1_555 ? ? ? ? ? ? ? 2.011 ? ?
disulf2 disulf ? ? A CYS 160 SG ? ? ? 1_555 A CYS 182 SG ? ? A CYS 160 A CYS 182 1_555 ? ? ? ? ? ? ? 2.089 ? ?
disulf3 disulf ? ? A CYS 162 SG ? ? ? 1_555 A CYS 165 SG ? ? A CYS 162 A CYS 165 1_555 ? ? ? ? ? ? ? 2.030 ? ?
covale1 covale both ? B PCA 1 C ? ? ? 1_555 B ASN 2 N ? ? B PCA 251 B ASN 252 1_555 ? ? ? ? ? ? ? 1.324 ? ?
metalc1 metalc ? ? A GLN 7 OE1 ? ? ? 1_555 G CD . CD ? ? A GLN 7 A CD 985 1_555 ? ? ? ? ? ? ? 2.234 ? ?
metalc2 metalc ? ? A HIS 18 NE2 ? ? ? 1_555 F CD . CD ? ? A HIS 18 A CD 984 1_555 ? ? ? ? ? ? ? 2.286 ? ?
metalc3 metalc ? ? A HIS 36 ND1 ? ? ? 1_555 D CD . CD ? ? A HIS 36 A CD 982 1_555 ? ? ? ? ? ? ? 2.384 ? ?
metalc4 metalc ? ? A ASN 50 OD1 ? ? ? 1_555 G CD . CD ? ? A ASN 50 A CD 985 1_555 ? ? ? ? ? ? ? 2.183 ? ?
metalc5 metalc ? ? A GLU 85 OE2 ? ? ? 1_555 L CD . CD ? ? A GLU 85 A CD 990 1_555 ? ? ? ? ? ? ? 2.427 ? ?
metalc6 metalc ? ? A GLU 85 OE1 ? ? ? 1_555 L CD . CD ? ? A GLU 85 A CD 990 1_555 ? ? ? ? ? ? ? 2.267 ? ?
metalc7 metalc ? ? A GLU 85 OE2 ? ? ? 8_555 L CD . CD ? ? A GLU 85 A CD 990 1_555 ? ? ? ? ? ? ? 2.412 ? ?
metalc8 metalc ? ? A GLU 85 OE1 ? ? ? 8_555 L CD . CD ? ? A GLU 85 A CD 990 1_555 ? ? ? ? ? ? ? 2.236 ? ?
metalc9 metalc ? ? A GLU 85 OE2 ? ? ? 1_555 M CD . CD ? ? A GLU 85 A CD 991 1_555 ? ? ? ? ? ? ? 2.736 ? ?
metalc10 metalc ? ? A GLU 121 OE1 ? ? ? 1_555 M CD . CD ? ? A GLU 121 A CD 991 1_555 ? ? ? ? ? ? ? 2.203 ? ?
metalc11 metalc ? ? A HIS 131 ND1 ? ? ? 1_555 J CD . CD ? ? A HIS 131 A CD 988 1_555 ? ? ? ? ? ? ? 2.234 ? ?
metalc12 metalc ? ? A HIS 131 O ? ? ? 1_555 J CD . CD ? ? A HIS 131 A CD 988 1_555 ? ? ? ? ? ? ? 2.544 ? ?
metalc13 metalc ? ? A HIS 144 NE2 ? ? ? 1_555 C CD . CD ? ? A HIS 144 A CD 981 1_555 ? ? ? ? ? ? ? 2.280 ? ?
metalc14 metalc ? ? A HIS 148 NE2 ? ? ? 1_555 C CD . CD ? ? A HIS 148 A CD 981 1_555 ? ? ? ? ? ? ? 2.229 ? ?
metalc15 metalc ? ? A HIS 154 NE2 ? ? ? 1_555 C CD . CD ? ? A HIS 154 A CD 981 1_555 ? ? ? ? ? ? ? 2.181 ? ?
metalc16 metalc ? ? A ASP 156 OD1 ? ? ? 3_555 D CD . CD ? ? A ASP 156 A CD 982 1_555 ? ? ? ? ? ? ? 2.427 ? ?
metalc17 metalc ? ? A ASP 156 OD2 ? ? ? 3_555 D CD . CD ? ? A ASP 156 A CD 982 1_555 ? ? ? ? ? ? ? 2.256 ? ?
metalc18 metalc ? ? A ASP 158 OD2 ? ? ? 3_555 D CD . CD ? ? A ASP 158 A CD 982 1_555 ? ? ? ? ? ? ? 2.282 ? ?
metalc19 metalc ? ? A ASP 181 OD2 ? ? ? 1_555 E CD . CD ? ? A ASP 181 A CD 983 1_555 ? ? ? ? ? ? ? 2.285 ? ?
metalc20 metalc ? ? A ASP 181 OD1 ? ? ? 1_555 E CD . CD ? ? A ASP 181 A CD 983 1_555 ? ? ? ? ? ? ? 2.596 ? ?
metalc21 metalc ? ? A ASP 185 OD1 ? ? ? 1_555 E CD . CD ? ? A ASP 185 A CD 983 1_555 ? ? ? ? ? ? ? 2.680 ? ?
metalc22 metalc ? ? A ASP 185 OD2 ? ? ? 1_555 E CD . CD ? ? A ASP 185 A CD 983 1_555 ? ? ? ? ? ? ? 2.320 ? ?
metalc23 metalc ? ? A ASP 194 OD1 ? ? ? 1_555 H CD . CD ? ? A ASP 194 A CD 986 1_555 ? ? ? ? ? ? ? 2.342 ? ?
metalc24 metalc ? ? A ASP 194 OD2 ? ? ? 1_555 H CD . CD ? ? A ASP 194 A CD 986 1_555 ? ? ? ? ? ? ? 2.230 ? ?
metalc25 metalc ? ? A PRO 203 O ? ? ? 1_555 I CD . CD ? ? A PRO 203 A CD 987 1_555 ? ? ? ? ? ? ? 2.328 ? ?
metalc26 metalc ? ? A PRO 203 OXT ? ? ? 1_555 I CD . CD ? ? A PRO 203 A CD 987 1_555 ? ? ? ? ? ? ? 2.399 ? ?
metalc27 metalc ? ? N HOH . O ? ? ? 1_555 G CD . CD ? ? A HOH 319 A CD 985 1_555 ? ? ? ? ? ? ? 2.562 ? ?
metalc28 metalc ? ? N HOH . O ? ? ? 1_555 G CD . CD ? ? A HOH 320 A CD 985 1_555 ? ? ? ? ? ? ? 2.558 ? ?
metalc29 metalc ? ? N HOH . O ? ? ? 4_454 E CD . CD ? ? A HOH 325 A CD 983 1_555 ? ? ? ? ? ? ? 2.552 ? ?
metalc30 metalc ? ? N HOH . O ? ? ? 1_555 D CD . CD ? ? A HOH 348 A CD 982 1_555 ? ? ? ? ? ? ? 2.412 ? ?
metalc31 metalc ? ? N HOH . O ? ? ? 1_555 D CD . CD ? ? A HOH 349 A CD 982 1_555 ? ? ? ? ? ? ? 2.363 ? ?
metalc32 metalc ? ? N HOH . O ? ? ? 1_555 J CD . CD ? ? A HOH 354 A CD 988 1_555 ? ? ? ? ? ? ? 2.360 ? ?
metalc33 metalc ? ? N HOH . O ? ? ? 1_555 J CD . CD ? ? A HOH 355 A CD 988 1_555 ? ? ? ? ? ? ? 2.550 ? ?
metalc34 metalc ? ? N HOH . O ? ? ? 1_555 J CD . CD ? ? A HOH 356 A CD 988 1_555 ? ? ? ? ? ? ? 2.363 ? ?
metalc35 metalc ? ? N HOH . O ? ? ? 1_555 K CD . CD ? ? A HOH 380 A CD 989 1_555 ? ? ? ? ? ? ? 2.582 ? ?
metalc36 metalc ? ? N HOH . O ? ? ? 1_555 K CD . CD ? ? A HOH 386 A CD 989 1_555 ? ? ? ? ? ? ? 2.333 ? ?
metalc37 metalc ? ? N HOH . O ? ? ? 3_555 I CD . CD ? ? A HOH 392 A CD 987 1_555 ? ? ? ? ? ? ? 2.851 ? ?
metalc38 metalc ? ? N HOH . O ? ? ? 1_555 J CD . CD ? ? A HOH 424 A CD 988 1_555 ? ? ? ? ? ? ? 2.433 ? ?
metalc39 metalc ? ? N HOH . O ? ? ? 1_555 E CD . CD ? ? A HOH 431 A CD 983 1_555 ? ? ? ? ? ? ? 2.315 ? ?
metalc40 metalc ? ? N HOH . O ? ? ? 1_555 E CD . CD ? ? A HOH 433 A CD 983 1_555 ? ? ? ? ? ? ? 2.334 ? ?
metalc41 metalc ? ? N HOH . O ? ? ? 1_555 G CD . CD ? ? A HOH 438 A CD 985 1_555 ? ? ? ? ? ? ? 2.430 ? ?
metalc42 metalc ? ? N HOH . O ? ? ? 1_555 H CD . CD ? ? A HOH 442 A CD 986 1_555 ? ? ? ? ? ? ? 2.815 ? ?
metalc43 metalc ? ? N HOH . O ? ? ? 1_555 M CD . CD ? ? A HOH 455 A CD 991 1_555 ? ? ? ? ? ? ? 2.493 ? ?
metalc44 metalc ? ? N HOH . O ? ? ? 1_555 K CD . CD ? ? A HOH 550 A CD 989 1_555 ? ? ? ? ? ? ? 2.504 ? ?
metalc45 metalc ? ? N HOH . O ? ? ? 1_555 K CD . CD ? ? A HOH 551 A CD 989 1_555 ? ? ? ? ? ? ? 1.882 ? ?
metalc46 metalc ? ? N HOH . O ? ? ? 1_555 K CD . CD ? ? A HOH 552 A CD 989 1_555 ? ? ? ? ? ? ? 2.297 ? ?
metalc47 metalc ? ? N HOH . O ? ? ? 1_555 H CD . CD ? ? A HOH 571 A CD 986 1_555 ? ? ? ? ? ? ? 2.221 ? ?
metalc48 metalc ? ? N HOH . O ? ? ? 1_555 F CD . CD ? ? A HOH 583 A CD 984 1_555 ? ? ? ? ? ? ? 2.491 ? ?
metalc49 metalc ? ? N HOH . O ? ? ? 3_555 I CD . CD ? ? A HOH 598 A CD 987 1_555 ? ? ? ? ? ? ? 2.946 ? ?
metalc50 metalc ? ? N HOH . O ? ? ? 1_555 L CD . CD ? ? A HOH 617 A CD 990 1_555 ? ? ? ? ? ? ? 2.519 ? ?
metalc51 metalc ? ? N HOH . O ? ? ? 8_555 L CD . CD ? ? A HOH 617 A CD 990 1_555 ? ? ? ? ? ? ? 2.519 ? ?
metalc52 metalc ? ? N HOH . O ? ? ? 1_555 L CD . CD ? ? A HOH 618 A CD 990 1_555 ? ? ? ? ? ? ? 2.618 ? ?
metalc53 metalc ? ? N HOH . O ? ? ? 8_555 L CD . CD ? ? A HOH 618 A CD 990 1_555 ? ? ? ? ? ? ? 2.714 ? ?
metalc54 metalc ? ? N HOH . O ? ? ? 1_555 G CD . CD ? ? A HOH 666 A CD 985 1_555 ? ? ? ? ? ? ? 2.288 ? ?
metalc55 metalc ? ? N HOH . O ? ? ? 1_555 F CD . CD ? ? A HOH 721 A CD 984 1_555 ? ? ? ? ? ? ? 2.299 ? ?
metalc56 metalc ? ? N HOH . O ? ? ? 1_555 I CD . CD ? ? A HOH 746 A CD 987 1_555 ? ? ? ? ? ? ? 1.829 ? ?
metalc57 metalc ? ? N HOH . O ? ? ? 1_555 I CD . CD ? ? A HOH 747 A CD 987 1_555 ? ? ? ? ? ? ? 2.090 ? ?
metalc58 metalc ? ? N HOH . O ? ? ? 1_555 M CD . CD ? ? A HOH 803 A CD 991 1_555 ? ? ? ? ? ? ? 1.925 ? ?
metalc59 metalc ? ? N HOH . O ? ? ? 8_555 M CD . CD ? ? A HOH 803 A CD 991 1_555 ? ? ? ? ? ? ? 2.191 ? ?
metalc60 metalc ? ? N HOH . O ? ? ? 1_555 F CD . CD ? ? A HOH 821 A CD 984 1_555 ? ? ? ? ? ? ? 2.341 ? ?
metalc61 metalc ? ? N HOH . O ? ? ? 1_555 K CD . CD ? ? A HOH 836 A CD 989 1_555 ? ? ? ? ? ? ? 2.050 ? ?
metalc62 metalc ? ? N HOH . O ? ? ? 1_555 I CD . CD ? ? A HOH 837 A CD 987 1_555 ? ? ? ? ? ? ? 1.977 ? ?
metalc63 metalc ? ? N HOH . O ? ? ? 1_555 K CD . CD ? ? A HOH 885 A CD 989 1_555 ? ? ? ? ? ? ? 3.134 ? ?
metalc64 metalc ? ? N HOH . O ? ? ? 1_555 F CD . CD ? ? A HOH 914 A CD 984 1_555 ? ? ? ? ? ? ? 3.112 ? ?
metalc65 metalc ? ? C CD . CD ? ? ? 1_555 B TRP 3 O ? ? A CD 981 B TRP 253 1_555 ? ? ? ? ? ? ? 2.464 ? ?
metalc66 metalc ? ? C CD . CD ? ? ? 1_555 B TRP 3 OXT ? ? A CD 981 B TRP 253 1_555 ? ? ? ? ? ? ? 2.263 ? ?
metalc67 metalc ? ? C CD . CD ? ? ? 1_555 O HOH . O ? ? A CD 981 B HOH 413 1_555 ? ? ? ? ? ? ? 2.421 ? ?
#
loop_
_struct_conn_type.id
_struct_conn_type.criteria
_struct_conn_type.reference
disulf ? ?
covale ? ?
metalc ? ?
#
loop_
_pdbx_struct_conn_angle.id
_pdbx_struct_conn_angle.ptnr1_label_atom_id
_pdbx_struct_conn_angle.ptnr1_label_alt_id
_pdbx_struct_conn_angle.ptnr1_label_asym_id
_pdbx_struct_conn_angle.ptnr1_label_comp_id
_pdbx_struct_conn_angle.ptnr1_label_seq_id
_pdbx_struct_conn_angle.ptnr1_auth_atom_id
_pdbx_struct_conn_angle.ptnr1_auth_asym_id
_pdbx_struct_conn_angle.ptnr1_auth_comp_id
_pdbx_struct_conn_angle.ptnr1_auth_seq_id
_pdbx_struct_conn_angle.ptnr1_PDB_ins_code
_pdbx_struct_conn_angle.ptnr1_symmetry
_pdbx_struct_conn_angle.ptnr2_label_atom_id
_pdbx_struct_conn_angle.ptnr2_label_alt_id
_pdbx_struct_conn_angle.ptnr2_label_asym_id
_pdbx_struct_conn_angle.ptnr2_label_comp_id
_pdbx_struct_conn_angle.ptnr2_label_seq_id
_pdbx_struct_conn_angle.ptnr2_auth_atom_id
_pdbx_struct_conn_angle.ptnr2_auth_asym_id
_pdbx_struct_conn_angle.ptnr2_auth_comp_id
_pdbx_struct_conn_angle.ptnr2_auth_seq_id
_pdbx_struct_conn_angle.ptnr2_PDB_ins_code
_pdbx_struct_conn_angle.ptnr2_symmetry
_pdbx_struct_conn_angle.ptnr3_label_atom_id
_pdbx_struct_conn_angle.ptnr3_label_alt_id
_pdbx_struct_conn_angle.ptnr3_label_asym_id
_pdbx_struct_conn_angle.ptnr3_label_comp_id
_pdbx_struct_conn_angle.ptnr3_label_seq_id
_pdbx_struct_conn_angle.ptnr3_auth_atom_id
_pdbx_struct_conn_angle.ptnr3_auth_asym_id
_pdbx_struct_conn_angle.ptnr3_auth_comp_id
_pdbx_struct_conn_angle.ptnr3_auth_seq_id
_pdbx_struct_conn_angle.ptnr3_PDB_ins_code
_pdbx_struct_conn_angle.ptnr3_symmetry
_pdbx_struct_conn_angle.value
_pdbx_struct_conn_angle.value_esd
1 OE1 ? A GLN 7 ? A GLN 7 ? 1_555 CD ? G CD . ? A CD 985 ? 1_555 OD1 ? A ASN 50 ? A ASN 50 ? 1_555 95.0 ?
2 OE1 ? A GLN 7 ? A GLN 7 ? 1_555 CD ? G CD . ? A CD 985 ? 1_555 O ? N HOH . ? A HOH 319 ? 1_555 88.1 ?
3 OD1 ? A ASN 50 ? A ASN 50 ? 1_555 CD ? G CD . ? A CD 985 ? 1_555 O ? N HOH . ? A HOH 319 ? 1_555 91.4 ?
4 OE1 ? A GLN 7 ? A GLN 7 ? 1_555 CD ? G CD . ? A CD 985 ? 1_555 O ? N HOH . ? A HOH 320 ? 1_555 85.9 ?
5 OD1 ? A ASN 50 ? A ASN 50 ? 1_555 CD ? G CD . ? A CD 985 ? 1_555 O ? N HOH . ? A HOH 320 ? 1_555 82.5 ?
6 O ? N HOH . ? A HOH 319 ? 1_555 CD ? G CD . ? A CD 985 ? 1_555 O ? N HOH . ? A HOH 320 ? 1_555 171.0 ?
7 OE1 ? A GLN 7 ? A GLN 7 ? 1_555 CD ? G CD . ? A CD 985 ? 1_555 O ? N HOH . ? A HOH 438 ? 1_555 84.7 ?
8 OD1 ? A ASN 50 ? A ASN 50 ? 1_555 CD ? G CD . ? A CD 985 ? 1_555 O ? N HOH . ? A HOH 438 ? 1_555 173.6 ?
9 O ? N HOH . ? A HOH 319 ? 1_555 CD ? G CD . ? A CD 985 ? 1_555 O ? N HOH . ? A HOH 438 ? 1_555 95.0 ?
10 O ? N HOH . ? A HOH 320 ? 1_555 CD ? G CD . ? A CD 985 ? 1_555 O ? N HOH . ? A HOH 438 ? 1_555 91.2 ?
11 OE1 ? A GLN 7 ? A GLN 7 ? 1_555 CD ? G CD . ? A CD 985 ? 1_555 O ? N HOH . ? A HOH 666 ? 1_555 177.1 ?
12 OD1 ? A ASN 50 ? A ASN 50 ? 1_555 CD ? G CD . ? A CD 985 ? 1_555 O ? N HOH . ? A HOH 666 ? 1_555 83.4 ?
13 O ? N HOH . ? A HOH 319 ? 1_555 CD ? G CD . ? A CD 985 ? 1_555 O ? N HOH . ? A HOH 666 ? 1_555 89.5 ?
14 O ? N HOH . ? A HOH 320 ? 1_555 CD ? G CD . ? A CD 985 ? 1_555 O ? N HOH . ? A HOH 666 ? 1_555 96.3 ?
15 O ? N HOH . ? A HOH 438 ? 1_555 CD ? G CD . ? A CD 985 ? 1_555 O ? N HOH . ? A HOH 666 ? 1_555 97.2 ?
16 NE2 ? A HIS 18 ? A HIS 18 ? 1_555 CD ? F CD . ? A CD 984 ? 1_555 O ? N HOH . ? A HOH 583 ? 1_555 103.3 ?
17 NE2 ? A HIS 18 ? A HIS 18 ? 1_555 CD ? F CD . ? A CD 984 ? 1_555 O ? N HOH . ? A HOH 721 ? 1_555 91.8 ?
18 O ? N HOH . ? A HOH 583 ? 1_555 CD ? F CD . ? A CD 984 ? 1_555 O ? N HOH . ? A HOH 721 ? 1_555 82.5 ?
19 NE2 ? A HIS 18 ? A HIS 18 ? 1_555 CD ? F CD . ? A CD 984 ? 1_555 O ? N HOH . ? A HOH 821 ? 1_555 94.3 ?
20 O ? N HOH . ? A HOH 583 ? 1_555 CD ? F CD . ? A CD 984 ? 1_555 O ? N HOH . ? A HOH 821 ? 1_555 119.9 ?
21 O ? N HOH . ? A HOH 721 ? 1_555 CD ? F CD . ? A CD 984 ? 1_555 O ? N HOH . ? A HOH 821 ? 1_555 154.4 ?
22 NE2 ? A HIS 18 ? A HIS 18 ? 1_555 CD ? F CD . ? A CD 984 ? 1_555 O ? N HOH . ? A HOH 914 ? 1_555 79.0 ?
23 O ? N HOH . ? A HOH 583 ? 1_555 CD ? F CD . ? A CD 984 ? 1_555 O ? N HOH . ? A HOH 914 ? 1_555 171.5 ?
24 O ? N HOH . ? A HOH 721 ? 1_555 CD ? F CD . ? A CD 984 ? 1_555 O ? N HOH . ? A HOH 914 ? 1_555 89.2 ?
25 O ? N HOH . ? A HOH 821 ? 1_555 CD ? F CD . ? A CD 984 ? 1_555 O ? N HOH . ? A HOH 914 ? 1_555 67.7 ?
26 ND1 ? A HIS 36 ? A HIS 36 ? 1_555 CD ? D CD . ? A CD 982 ? 1_555 OD1 ? A ASP 156 ? A ASP 156 ? 3_555 90.4 ?
27 ND1 ? A HIS 36 ? A HIS 36 ? 1_555 CD ? D CD . ? A CD 982 ? 1_555 OD2 ? A ASP 156 ? A ASP 156 ? 3_555 97.0 ?
28 OD1 ? A ASP 156 ? A ASP 156 ? 3_555 CD ? D CD . ? A CD 982 ? 1_555 OD2 ? A ASP 156 ? A ASP 156 ? 3_555 54.2 ?
29 ND1 ? A HIS 36 ? A HIS 36 ? 1_555 CD ? D CD . ? A CD 982 ? 1_555 OD2 ? A ASP 158 ? A ASP 158 ? 3_555 91.9 ?
30 OD1 ? A ASP 156 ? A ASP 156 ? 3_555 CD ? D CD . ? A CD 982 ? 1_555 OD2 ? A ASP 158 ? A ASP 158 ? 3_555 94.7 ?
31 OD2 ? A ASP 156 ? A ASP 156 ? 3_555 CD ? D CD . ? A CD 982 ? 1_555 OD2 ? A ASP 158 ? A ASP 158 ? 3_555 147.5 ?
32 ND1 ? A HIS 36 ? A HIS 36 ? 1_555 CD ? D CD . ? A CD 982 ? 1_555 O ? N HOH . ? A HOH 348 ? 1_555 99.0 ?
33 OD1 ? A ASP 156 ? A ASP 156 ? 3_555 CD ? D CD . ? A CD 982 ? 1_555 O ? N HOH . ? A HOH 348 ? 1_555 158.3 ?
34 OD2 ? A ASP 156 ? A ASP 156 ? 3_555 CD ? D CD . ? A CD 982 ? 1_555 O ? N HOH . ? A HOH 348 ? 1_555 104.9 ?
35 OD2 ? A ASP 158 ? A ASP 158 ? 3_555 CD ? D CD . ? A CD 982 ? 1_555 O ? N HOH . ? A HOH 348 ? 1_555 104.4 ?
36 ND1 ? A HIS 36 ? A HIS 36 ? 1_555 CD ? D CD . ? A CD 982 ? 1_555 O ? N HOH . ? A HOH 349 ? 1_555 160.8 ?
37 OD1 ? A ASP 156 ? A ASP 156 ? 3_555 CD ? D CD . ? A CD 982 ? 1_555 O ? N HOH . ? A HOH 349 ? 1_555 78.5 ?
38 OD2 ? A ASP 156 ? A ASP 156 ? 3_555 CD ? D CD . ? A CD 982 ? 1_555 O ? N HOH . ? A HOH 349 ? 1_555 89.1 ?
39 OD2 ? A ASP 158 ? A ASP 158 ? 3_555 CD ? D CD . ? A CD 982 ? 1_555 O ? N HOH . ? A HOH 349 ? 1_555 73.8 ?
40 O ? N HOH . ? A HOH 348 ? 1_555 CD ? D CD . ? A CD 982 ? 1_555 O ? N HOH . ? A HOH 349 ? 1_555 96.9 ?
41 OE2 ? A GLU 85 ? A GLU 85 ? 1_555 CD ? L CD . ? A CD 990 ? 1_555 OE1 ? A GLU 85 ? A GLU 85 ? 1_555 55.3 ?
42 OE2 ? A GLU 85 ? A GLU 85 ? 1_555 CD ? L CD . ? A CD 990 ? 1_555 OE2 ? A GLU 85 ? A GLU 85 ? 8_555 73.6 ?
43 OE1 ? A GLU 85 ? A GLU 85 ? 1_555 CD ? L CD . ? A CD 990 ? 1_555 OE2 ? A GLU 85 ? A GLU 85 ? 8_555 128.5 ?
44 OE2 ? A GLU 85 ? A GLU 85 ? 1_555 CD ? L CD . ? A CD 990 ? 1_555 OE1 ? A GLU 85 ? A GLU 85 ? 8_555 129.3 ?
45 OE1 ? A GLU 85 ? A GLU 85 ? 1_555 CD ? L CD . ? A CD 990 ? 1_555 OE1 ? A GLU 85 ? A GLU 85 ? 8_555 174.9 ?
46 OE2 ? A GLU 85 ? A GLU 85 ? 8_555 CD ? L CD . ? A CD 990 ? 1_555 OE1 ? A GLU 85 ? A GLU 85 ? 8_555 55.8 ?
47 OE2 ? A GLU 85 ? A GLU 85 ? 1_555 CD ? L CD . ? A CD 990 ? 1_555 O ? N HOH . ? A HOH 617 ? 1_555 142.3 ?
48 OE1 ? A GLU 85 ? A GLU 85 ? 1_555 CD ? L CD . ? A CD 990 ? 1_555 O ? N HOH . ? A HOH 617 ? 1_555 87.0 ?
49 OE2 ? A GLU 85 ? A GLU 85 ? 8_555 CD ? L CD . ? A CD 990 ? 1_555 O ? N HOH . ? A HOH 617 ? 1_555 144.0 ?
50 OE1 ? A GLU 85 ? A GLU 85 ? 8_555 CD ? L CD . ? A CD 990 ? 1_555 O ? N HOH . ? A HOH 617 ? 1_555 88.4 ?
51 OE2 ? A GLU 85 ? A GLU 85 ? 1_555 CD ? L CD . ? A CD 990 ? 1_555 O ? N HOH . ? A HOH 617 ? 8_555 143.0 ?
52 OE1 ? A GLU 85 ? A GLU 85 ? 1_555 CD ? L CD . ? A CD 990 ? 1_555 O ? N HOH . ? A HOH 617 ? 8_555 87.7 ?
53 OE2 ? A GLU 85 ? A GLU 85 ? 8_555 CD ? L CD . ? A CD 990 ? 1_555 O ? N HOH . ? A HOH 617 ? 8_555 143.3 ?
54 OE1 ? A GLU 85 ? A GLU 85 ? 8_555 CD ? L CD . ? A CD 990 ? 1_555 O ? N HOH . ? A HOH 617 ? 8_555 87.7 ?
55 O ? N HOH . ? A HOH 617 ? 1_555 CD ? L CD . ? A CD 990 ? 1_555 O ? N HOH . ? A HOH 617 ? 8_555 0.7 ?
56 OE2 ? A GLU 85 ? A GLU 85 ? 1_555 CD ? L CD . ? A CD 990 ? 1_555 O ? N HOH . ? A HOH 618 ? 1_555 96.7 ?
57 OE1 ? A GLU 85 ? A GLU 85 ? 1_555 CD ? L CD . ? A CD 990 ? 1_555 O ? N HOH . ? A HOH 618 ? 1_555 95.5 ?
58 OE2 ? A GLU 85 ? A GLU 85 ? 8_555 CD ? L CD . ? A CD 990 ? 1_555 O ? N HOH . ? A HOH 618 ? 1_555 95.9 ?
59 OE1 ? A GLU 85 ? A GLU 85 ? 8_555 CD ? L CD . ? A CD 990 ? 1_555 O ? N HOH . ? A HOH 618 ? 1_555 86.4 ?
60 O ? N HOH . ? A HOH 617 ? 1_555 CD ? L CD . ? A CD 990 ? 1_555 O ? N HOH . ? A HOH 618 ? 1_555 84.7 ?
61 O ? N HOH . ? A HOH 617 ? 8_555 CD ? L CD . ? A CD 990 ? 1_555 O ? N HOH . ? A HOH 618 ? 1_555 84.6 ?
62 OE2 ? A GLU 85 ? A GLU 85 ? 1_555 CD ? L CD . ? A CD 990 ? 1_555 O ? N HOH . ? A HOH 618 ? 8_555 93.1 ?
63 OE1 ? A GLU 85 ? A GLU 85 ? 1_555 CD ? L CD . ? A CD 990 ? 1_555 O ? N HOH . ? A HOH 618 ? 8_555 83.5 ?
64 OE2 ? A GLU 85 ? A GLU 85 ? 8_555 CD ? L CD . ? A CD 990 ? 1_555 O ? N HOH . ? A HOH 618 ? 8_555 94.5 ?
65 OE1 ? A GLU 85 ? A GLU 85 ? 8_555 CD ? L CD . ? A CD 990 ? 1_555 O ? N HOH . ? A HOH 618 ? 8_555 93.6 ?
66 O ? N HOH . ? A HOH 617 ? 1_555 CD ? L CD . ? A CD 990 ? 1_555 O ? N HOH . ? A HOH 618 ? 8_555 82.7 ?
67 O ? N HOH . ? A HOH 617 ? 8_555 CD ? L CD . ? A CD 990 ? 1_555 O ? N HOH . ? A HOH 618 ? 8_555 82.7 ?
68 O ? N HOH . ? A HOH 618 ? 1_555 CD ? L CD . ? A CD 990 ? 1_555 O ? N HOH . ? A HOH 618 ? 8_555 167.3 ?
69 OE2 ? A GLU 85 ? A GLU 85 ? 1_555 CD ? M CD . ? A CD 991 ? 1_555 OE1 ? A GLU 121 ? A GLU 121 ? 1_555 106.0 ?
70 OE2 ? A GLU 85 ? A GLU 85 ? 1_555 CD ? M CD . ? A CD 991 ? 1_555 O ? N HOH . ? A HOH 455 ? 1_555 78.8 ?
71 OE1 ? A GLU 121 ? A GLU 121 ? 1_555 CD ? M CD . ? A CD 991 ? 1_555 O ? N HOH . ? A HOH 455 ? 1_555 97.6 ?
72 OE2 ? A GLU 85 ? A GLU 85 ? 1_555 CD ? M CD . ? A CD 991 ? 1_555 O ? N HOH . ? A HOH 803 ? 1_555 60.8 ?
73 OE1 ? A GLU 121 ? A GLU 121 ? 1_555 CD ? M CD . ? A CD 991 ? 1_555 O ? N HOH . ? A HOH 803 ? 1_555 84.7 ?
74 O ? N HOH . ? A HOH 455 ? 1_555 CD ? M CD . ? A CD 991 ? 1_555 O ? N HOH . ? A HOH 803 ? 1_555 138.3 ?
75 OE2 ? A GLU 85 ? A GLU 85 ? 1_555 CD ? M CD . ? A CD 991 ? 1_555 O ? N HOH . ? A HOH 803 ? 8_555 95.3 ?
76 OE1 ? A GLU 121 ? A GLU 121 ? 1_555 CD ? M CD . ? A CD 991 ? 1_555 O ? N HOH . ? A HOH 803 ? 8_555 157.3 ?
77 O ? N HOH . ? A HOH 455 ? 1_555 CD ? M CD . ? A CD 991 ? 1_555 O ? N HOH . ? A HOH 803 ? 8_555 94.1 ?
78 O ? N HOH . ? A HOH 803 ? 1_555 CD ? M CD . ? A CD 991 ? 1_555 O ? N HOH . ? A HOH 803 ? 8_555 99.3 ?
79 ND1 ? A HIS 131 ? A HIS 131 ? 1_555 CD ? J CD . ? A CD 988 ? 1_555 O ? A HIS 131 ? A HIS 131 ? 1_555 82.3 ?
80 ND1 ? A HIS 131 ? A HIS 131 ? 1_555 CD ? J CD . ? A CD 988 ? 1_555 O ? N HOH . ? A HOH 354 ? 1_555 98.6 ?
81 O ? A HIS 131 ? A HIS 131 ? 1_555 CD ? J CD . ? A CD 988 ? 1_555 O ? N HOH . ? A HOH 354 ? 1_555 86.7 ?
82 ND1 ? A HIS 131 ? A HIS 131 ? 1_555 CD ? J CD . ? A CD 988 ? 1_555 O ? N HOH . ? A HOH 355 ? 1_555 88.6 ?
83 O ? A HIS 131 ? A HIS 131 ? 1_555 CD ? J CD . ? A CD 988 ? 1_555 O ? N HOH . ? A HOH 355 ? 1_555 119.0 ?
84 O ? N HOH . ? A HOH 354 ? 1_555 CD ? J CD . ? A CD 988 ? 1_555 O ? N HOH . ? A HOH 355 ? 1_555 154.1 ?
85 ND1 ? A HIS 131 ? A HIS 131 ? 1_555 CD ? J CD . ? A CD 988 ? 1_555 O ? N HOH . ? A HOH 356 ? 1_555 101.2 ?
86 O ? A HIS 131 ? A HIS 131 ? 1_555 CD ? J CD . ? A CD 988 ? 1_555 O ? N HOH . ? A HOH 356 ? 1_555 148.3 ?
87 O ? N HOH . ? A HOH 354 ? 1_555 CD ? J CD . ? A CD 988 ? 1_555 O ? N HOH . ? A HOH 356 ? 1_555 61.6 ?
88 O ? N HOH . ? A HOH 355 ? 1_555 CD ? J CD . ? A CD 988 ? 1_555 O ? N HOH . ? A HOH 356 ? 1_555 92.7 ?
89 ND1 ? A HIS 131 ? A HIS 131 ? 1_555 CD ? J CD . ? A CD 988 ? 1_555 O ? N HOH . ? A HOH 424 ? 1_555 152.4 ?
90 O ? A HIS 131 ? A HIS 131 ? 1_555 CD ? J CD . ? A CD 988 ? 1_555 O ? N HOH . ? A HOH 424 ? 1_555 78.1 ?
91 O ? N HOH . ? A HOH 354 ? 1_555 CD ? J CD . ? A CD 988 ? 1_555 O ? N HOH . ? A HOH 424 ? 1_555 99.4 ?
92 O ? N HOH . ? A HOH 355 ? 1_555 CD ? J CD . ? A CD 988 ? 1_555 O ? N HOH . ? A HOH 424 ? 1_555 84.2 ?
93 O ? N HOH . ? A HOH 356 ? 1_555 CD ? J CD . ? A CD 988 ? 1_555 O ? N HOH . ? A HOH 424 ? 1_555 105.7 ?
94 NE2 ? A HIS 144 ? A HIS 144 ? 1_555 CD ? C CD . ? A CD 981 ? 1_555 NE2 ? A HIS 148 ? A HIS 148 ? 1_555 91.6 ?
95 NE2 ? A HIS 144 ? A HIS 144 ? 1_555 CD ? C CD . ? A CD 981 ? 1_555 NE2 ? A HIS 154 ? A HIS 154 ? 1_555 100.6 ?
96 NE2 ? A HIS 148 ? A HIS 148 ? 1_555 CD ? C CD . ? A CD 981 ? 1_555 NE2 ? A HIS 154 ? A HIS 154 ? 1_555 102.1 ?
97 NE2 ? A HIS 144 ? A HIS 144 ? 1_555 CD ? C CD . ? A CD 981 ? 1_555 O ? B TRP 3 ? B TRP 253 ? 1_555 81.5 ?
98 NE2 ? A HIS 148 ? A HIS 148 ? 1_555 CD ? C CD . ? A CD 981 ? 1_555 O ? B TRP 3 ? B TRP 253 ? 1_555 107.8 ?
99 NE2 ? A HIS 154 ? A HIS 154 ? 1_555 CD ? C CD . ? A CD 981 ? 1_555 O ? B TRP 3 ? B TRP 253 ? 1_555 150.0 ?
100 NE2 ? A HIS 144 ? A HIS 144 ? 1_555 CD ? C CD . ? A CD 981 ? 1_555 OXT ? B TRP 3 ? B TRP 253 ? 1_555 103.9 ?
101 NE2 ? A HIS 148 ? A HIS 148 ? 1_555 CD ? C CD . ? A CD 981 ? 1_555 OXT ? B TRP 3 ? B TRP 253 ? 1_555 152.9 ?
102 NE2 ? A HIS 154 ? A HIS 154 ? 1_555 CD ? C CD . ? A CD 981 ? 1_555 OXT ? B TRP 3 ? B TRP 253 ? 1_555 96.8 ?
103 O ? B TRP 3 ? B TRP 253 ? 1_555 CD ? C CD . ? A CD 981 ? 1_555 OXT ? B TRP 3 ? B TRP 253 ? 1_555 54.3 ?
104 NE2 ? A HIS 144 ? A HIS 144 ? 1_555 CD ? C CD . ? A CD 981 ? 1_555 O ? O HOH . ? B HOH 413 ? 1_555 163.1 ?
105 NE2 ? A HIS 148 ? A HIS 148 ? 1_555 CD ? C CD . ? A CD 981 ? 1_555 O ? O HOH . ? B HOH 413 ? 1_555 79.9 ?
106 NE2 ? A HIS 154 ? A HIS 154 ? 1_555 CD ? C CD . ? A CD 981 ? 1_555 O ? O HOH . ? B HOH 413 ? 1_555 95.4 ?
107 O ? B TRP 3 ? B TRP 253 ? 1_555 CD ? C CD . ? A CD 981 ? 1_555 O ? O HOH . ? B HOH 413 ? 1_555 87.2 ?
108 OXT ? B TRP 3 ? B TRP 253 ? 1_555 CD ? C CD . ? A CD 981 ? 1_555 O ? O HOH . ? B HOH 413 ? 1_555 79.1 ?
109 OD2 ? A ASP 181 ? A ASP 181 ? 1_555 CD ? E CD . ? A CD 983 ? 1_555 OD1 ? A ASP 181 ? A ASP 181 ? 1_555 53.0 ?
110 OD2 ? A ASP 181 ? A ASP 181 ? 1_555 CD ? E CD . ? A CD 983 ? 1_555 OD1 ? A ASP 185 ? A ASP 185 ? 1_555 105.1 ?
111 OD1 ? A ASP 181 ? A ASP 181 ? 1_555 CD ? E CD . ? A CD 983 ? 1_555 OD1 ? A ASP 185 ? A ASP 185 ? 1_555 78.3 ?
112 OD2 ? A ASP 181 ? A ASP 181 ? 1_555 CD ? E CD . ? A CD 983 ? 1_555 OD2 ? A ASP 185 ? A ASP 185 ? 1_555 87.2 ?
113 OD1 ? A ASP 181 ? A ASP 181 ? 1_555 CD ? E CD . ? A CD 983 ? 1_555 OD2 ? A ASP 185 ? A ASP 185 ? 1_555 104.6 ?
114 OD1 ? A ASP 185 ? A ASP 185 ? 1_555 CD ? E CD . ? A CD 983 ? 1_555 OD2 ? A ASP 185 ? A ASP 185 ? 1_555 51.1 ?
115 OD2 ? A ASP 181 ? A ASP 181 ? 1_555 CD ? E CD . ? A CD 983 ? 1_555 O ? N HOH . ? A HOH 325 ? 4_454 91.6 ?
116 OD1 ? A ASP 181 ? A ASP 181 ? 1_555 CD ? E CD . ? A CD 983 ? 1_555 O ? N HOH . ? A HOH 325 ? 4_454 139.4 ?
117 OD1 ? A ASP 185 ? A ASP 185 ? 1_555 CD ? E CD . ? A CD 983 ? 1_555 O ? N HOH . ? A HOH 325 ? 4_454 136.6 ?
118 OD2 ? A ASP 185 ? A ASP 185 ? 1_555 CD ? E CD . ? A CD 983 ? 1_555 O ? N HOH . ? A HOH 325 ? 4_454 91.1 ?
119 OD2 ? A ASP 181 ? A ASP 181 ? 1_555 CD ? E CD . ? A CD 983 ? 1_555 O ? N HOH . ? A HOH 431 ? 1_555 168.7 ?
120 OD1 ? A ASP 181 ? A ASP 181 ? 1_555 CD ? E CD . ? A CD 983 ? 1_555 O ? N HOH . ? A HOH 431 ? 1_555 115.6 ?
121 OD1 ? A ASP 185 ? A ASP 185 ? 1_555 CD ? E CD . ? A CD 983 ? 1_555 O ? N HOH . ? A HOH 431 ? 1_555 70.3 ?
122 OD2 ? A ASP 185 ? A ASP 185 ? 1_555 CD ? E CD . ? A CD 983 ? 1_555 O ? N HOH . ? A HOH 431 ? 1_555 97.0 ?
123 O ? N HOH . ? A HOH 325 ? 4_454 CD ? E CD . ? A CD 983 ? 1_555 O ? N HOH . ? A HOH 431 ? 1_555 98.8 ?
124 OD2 ? A ASP 181 ? A ASP 181 ? 1_555 CD ? E CD . ? A CD 983 ? 1_555 O ? N HOH . ? A HOH 433 ? 1_555 94.8 ?
125 OD1 ? A ASP 181 ? A ASP 181 ? 1_555 CD ? E CD . ? A CD 983 ? 1_555 O ? N HOH . ? A HOH 433 ? 1_555 74.5 ?
126 OD1 ? A ASP 185 ? A ASP 185 ? 1_555 CD ? E CD . ? A CD 983 ? 1_555 O ? N HOH . ? A HOH 433 ? 1_555 125.5 ?
127 OD2 ? A ASP 185 ? A ASP 185 ? 1_555 CD ? E CD . ? A CD 983 ? 1_555 O ? N HOH . ? A HOH 433 ? 1_555 176.5 ?
128 O ? N HOH . ? A HOH 325 ? 4_454 CD ? E CD . ? A CD 983 ? 1_555 O ? N HOH . ? A HOH 433 ? 1_555 91.7 ?
129 O ? N HOH . ? A HOH 431 ? 1_555 CD ? E CD . ? A CD 983 ? 1_555 O ? N HOH . ? A HOH 433 ? 1_555 80.5 ?
130 OD1 ? A ASP 194 ? A ASP 194 ? 1_555 CD ? H CD . ? A CD 986 ? 1_555 OD2 ? A ASP 194 ? A ASP 194 ? 1_555 57.4 ?
131 OD1 ? A ASP 194 ? A ASP 194 ? 1_555 CD ? H CD . ? A CD 986 ? 1_555 O ? N HOH . ? A HOH 442 ? 1_555 123.2 ?
132 OD2 ? A ASP 194 ? A ASP 194 ? 1_555 CD ? H CD . ? A CD 986 ? 1_555 O ? N HOH . ? A HOH 442 ? 1_555 178.7 ?
133 OD1 ? A ASP 194 ? A ASP 194 ? 1_555 CD ? H CD . ? A CD 986 ? 1_555 O ? N HOH . ? A HOH 571 ? 1_555 87.6 ?
134 OD2 ? A ASP 194 ? A ASP 194 ? 1_555 CD ? H CD . ? A CD 986 ? 1_555 O ? N HOH . ? A HOH 571 ? 1_555 102.2 ?
135 O ? N HOH . ? A HOH 442 ? 1_555 CD ? H CD . ? A CD 986 ? 1_555 O ? N HOH . ? A HOH 571 ? 1_555 76.9 ?
136 O ? A PRO 203 ? A PRO 203 ? 1_555 CD ? I CD . ? A CD 987 ? 1_555 OXT ? A PRO 203 ? A PRO 203 ? 1_555 54.9 ?
137 O ? A PRO 203 ? A PRO 203 ? 1_555 CD ? I CD . ? A CD 987 ? 1_555 O ? N HOH . ? A HOH 392 ? 3_555 151.8 ?
138 OXT ? A PRO 203 ? A PRO 203 ? 1_555 CD ? I CD . ? A CD 987 ? 1_555 O ? N HOH . ? A HOH 392 ? 3_555 99.5 ?
139 O ? A PRO 203 ? A PRO 203 ? 1_555 CD ? I CD . ? A CD 987 ? 1_555 O ? N HOH . ? A HOH 598 ? 3_555 130.5 ?
140 OXT ? A PRO 203 ? A PRO 203 ? 1_555 CD ? I CD . ? A CD 987 ? 1_555 O ? N HOH . ? A HOH 598 ? 3_555 138.8 ?
141 O ? N HOH . ? A HOH 392 ? 3_555 CD ? I CD . ? A CD 987 ? 1_555 O ? N HOH . ? A HOH 598 ? 3_555 75.8 ?
142 O ? A PRO 203 ? A PRO 203 ? 1_555 CD ? I CD . ? A CD 987 ? 1_555 O ? N HOH . ? A HOH 746 ? 1_555 72.2 ?
143 OXT ? A PRO 203 ? A PRO 203 ? 1_555 CD ? I CD . ? A CD 987 ? 1_555 O ? N HOH . ? A HOH 746 ? 1_555 126.6 ?
144 O ? N HOH . ? A HOH 392 ? 3_555 CD ? I CD . ? A CD 987 ? 1_555 O ? N HOH . ? A HOH 746 ? 1_555 133.8 ?
145 O ? N HOH . ? A HOH 598 ? 3_555 CD ? I CD . ? A CD 987 ? 1_555 O ? N HOH . ? A HOH 746 ? 1_555 71.4 ?
146 O ? A PRO 203 ? A PRO 203 ? 1_555 CD ? I CD . ? A CD 987 ? 1_555 O ? N HOH . ? A HOH 747 ? 1_555 100.5 ?
147 OXT ? A PRO 203 ? A PRO 203 ? 1_555 CD ? I CD . ? A CD 987 ? 1_555 O ? N HOH . ? A HOH 747 ? 1_555 82.1 ?
148 O ? N HOH . ? A HOH 392 ? 3_555 CD ? I CD . ? A CD 987 ? 1_555 O ? N HOH . ? A HOH 747 ? 1_555 85.7 ?
149 O ? N HOH . ? A HOH 598 ? 3_555 CD ? I CD . ? A CD 987 ? 1_555 O ? N HOH . ? A HOH 747 ? 1_555 56.9 ?
150 O ? N HOH . ? A HOH 746 ? 1_555 CD ? I CD . ? A CD 987 ? 1_555 O ? N HOH . ? A HOH 747 ? 1_555 102.1 ?
151 O ? A PRO 203 ? A PRO 203 ? 1_555 CD ? I CD . ? A CD 987 ? 1_555 O ? N HOH . ? A HOH 837 ? 1_555 147.1 ?
152 OXT ? A PRO 203 ? A PRO 203 ? 1_555 CD ? I CD . ? A CD 987 ? 1_555 O ? N HOH . ? A HOH 837 ? 1_555 152.4 ?
153 O ? N HOH . ? A HOH 392 ? 3_555 CD ? I CD . ? A CD 987 ? 1_555 O ? N HOH . ? A HOH 837 ? 1_555 54.2 ?
154 O ? N HOH . ? A HOH 598 ? 3_555 CD ? I CD . ? A CD 987 ? 1_555 O ? N HOH . ? A HOH 837 ? 1_555 50.4 ?
155 O ? N HOH . ? A HOH 746 ? 1_555 CD ? I CD . ? A CD 987 ? 1_555 O ? N HOH . ? A HOH 837 ? 1_555 79.7 ?
156 O ? N HOH . ? A HOH 747 ? 1_555 CD ? I CD . ? A CD 987 ? 1_555 O ? N HOH . ? A HOH 837 ? 1_555 101.9 ?
157 O ? N HOH . ? A HOH 380 ? 1_555 CD ? K CD . ? A CD 989 ? 1_555 O ? N HOH . ? A HOH 386 ? 1_555 95.3 ?
158 O ? N HOH . ? A HOH 380 ? 1_555 CD ? K CD . ? A CD 989 ? 1_555 O ? N HOH . ? A HOH 550 ? 1_555 88.3 ?
159 O ? N HOH . ? A HOH 386 ? 1_555 CD ? K CD . ? A CD 989 ? 1_555 O ? N HOH . ? A HOH 550 ? 1_555 92.8 ?
160 O ? N HOH . ? A HOH 380 ? 1_555 CD ? K CD . ? A CD 989 ? 1_555 O ? N HOH . ? A HOH 551 ? 1_555 150.8 ?
161 O ? N HOH . ? A HOH 386 ? 1_555 CD ? K CD . ? A CD 989 ? 1_555 O ? N HOH . ? A HOH 551 ? 1_555 72.8 ?
162 O ? N HOH . ? A HOH 550 ? 1_555 CD ? K CD . ? A CD 989 ? 1_555 O ? N HOH . ? A HOH 551 ? 1_555 66.4 ?
163 O ? N HOH . ? A HOH 380 ? 1_555 CD ? K CD . ? A CD 989 ? 1_555 O ? N HOH . ? A HOH 552 ? 1_555 95.6 ?
164 O ? N HOH . ? A HOH 386 ? 1_555 CD ? K CD . ? A CD 989 ? 1_555 O ? N HOH . ? A HOH 552 ? 1_555 169.1 ?
165 O ? N HOH . ? A HOH 550 ? 1_555 CD ? K CD . ? A CD 989 ? 1_555 O ? N HOH . ? A HOH 552 ? 1_555 86.4 ?
166 O ? N HOH . ? A HOH 551 ? 1_555 CD ? K CD . ? A CD 989 ? 1_555 O ? N HOH . ? A HOH 552 ? 1_555 97.0 ?
167 O ? N HOH . ? A HOH 380 ? 1_555 CD ? K CD . ? A CD 989 ? 1_555 O ? N HOH . ? A HOH 836 ? 1_555 100.2 ?
168 O ? N HOH . ? A HOH 386 ? 1_555 CD ? K CD . ? A CD 989 ? 1_555 O ? N HOH . ? A HOH 836 ? 1_555 94.4 ?
169 O ? N HOH . ? A HOH 550 ? 1_555 CD ? K CD . ? A CD 989 ? 1_555 O ? N HOH . ? A HOH 836 ? 1_555 168.3 ?
170 O ? N HOH . ? A HOH 551 ? 1_555 CD ? K CD . ? A CD 989 ? 1_555 O ? N HOH . ? A HOH 836 ? 1_555 107.2 ?
171 O ? N HOH . ? A HOH 552 ? 1_555 CD ? K CD . ? A CD 989 ? 1_555 O ? N HOH . ? A HOH 836 ? 1_555 84.8 ?
172 O ? N HOH . ? A HOH 380 ? 1_555 CD ? K CD . ? A CD 989 ? 1_555 O ? N HOH . ? A HOH 885 ? 1_555 152.3 ?
173 O ? N HOH . ? A HOH 386 ? 1_555 CD ? K CD . ? A CD 989 ? 1_555 O ? N HOH . ? A HOH 885 ? 1_555 69.7 ?
174 O ? N HOH . ? A HOH 550 ? 1_555 CD ? K CD . ? A CD 989 ? 1_555 O ? N HOH . ? A HOH 885 ? 1_555 114.8 ?
175 O ? N HOH . ? A HOH 551 ? 1_555 CD ? K CD . ? A CD 989 ? 1_555 O ? N HOH . ? A HOH 885 ? 1_555 48.4 ?
176 O ? N HOH . ? A HOH 552 ? 1_555 CD ? K CD . ? A CD 989 ? 1_555 O ? N HOH . ? A HOH 885 ? 1_555 100.7 ?
177 O ? N HOH . ? A HOH 836 ? 1_555 CD ? K CD . ? A CD 989 ? 1_555 O ? N HOH . ? A HOH 885 ? 1_555 59.7 ?
#
loop_
_pdbx_modification_feature.ordinal
_pdbx_modification_feature.label_comp_id
_pdbx_modification_feature.label_asym_id
_pdbx_modification_feature.label_seq_id
_pdbx_modification_feature.label_alt_id
_pdbx_modification_feature.modified_residue_label_comp_id
_pdbx_modification_feature.modified_residue_label_asym_id
_pdbx_modification_feature.modified_residue_label_seq_id
_pdbx_modification_feature.modified_residue_label_alt_id
_pdbx_modification_feature.auth_comp_id
_pdbx_modification_feature.auth_asym_id
_pdbx_modification_feature.auth_seq_id
_pdbx_modification_feature.PDB_ins_code
_pdbx_modification_feature.symmetry
_pdbx_modification_feature.modified_residue_auth_comp_id
_pdbx_modification_feature.modified_residue_auth_asym_id
_pdbx_modification_feature.modified_residue_auth_seq_id
_pdbx_modification_feature.modified_residue_PDB_ins_code
_pdbx_modification_feature.modified_residue_symmetry
_pdbx_modification_feature.comp_id_linking_atom
_pdbx_modification_feature.modified_residue_id_linking_atom
_pdbx_modification_feature.modified_residue_id
_pdbx_modification_feature.ref_pcm_id
_pdbx_modification_feature.ref_comp_id
_pdbx_modification_feature.type
_pdbx_modification_feature.category
1 PCA B 1 ? . . . . PCA B 251 ? 1_555 . . . . . . . GLN 1 PCA 'Pyrrolidone carboxylic acid' 'Named protein modification'
2 CYS A 119 ? CYS A 198 ? CYS A 119 ? 1_555 CYS A 198 ? 1_555 SG SG . . . None 'Disulfide bridge'
3 CYS A 160 ? CYS A 182 ? CYS A 160 ? 1_555 CYS A 182 ? 1_555 SG SG . . . None 'Disulfide bridge'
4 CYS A 162 ? CYS A 165 ? CYS A 162 ? 1_555 CYS A 165 ? 1_555 SG SG . . . None 'Disulfide bridge'
#
_struct_sheet.id A
_struct_sheet.type ?
_struct_sheet.number_strands 5
_struct_sheet.details ?
#
loop_
_struct_sheet_order.sheet_id
_struct_sheet_order.range_id_1
_struct_sheet_order.range_id_2
_struct_sheet_order.offset
_struct_sheet_order.sense
A 1 2 ? parallel
A 2 3 ? parallel
A 3 4 ? parallel
A 4 5 ? anti-parallel
#
loop_
_struct_sheet_range.sheet_id
_struct_sheet_range.id
_struct_sheet_range.beg_label_comp_id
_struct_sheet_range.beg_label_asym_id
_struct_sheet_range.beg_label_seq_id
_struct_sheet_range.pdbx_beg_PDB_ins_code
_struct_sheet_range.end_label_comp_id
_struct_sheet_range.end_label_asym_id
_struct_sheet_range.end_label_seq_id
_struct_sheet_range.pdbx_end_PDB_ins_code
_struct_sheet_range.beg_auth_comp_id
_struct_sheet_range.beg_auth_asym_id
_struct_sheet_range.beg_auth_seq_id
_struct_sheet_range.end_auth_comp_id
_struct_sheet_range.end_auth_asym_id
_struct_sheet_range.end_auth_seq_id
A 1 ILE A 51 ? VAL A 60 ? ILE A 51 VAL A 60
A 2 ARG A 8 ? VAL A 16 ? ARG A 8 VAL A 16
A 3 HIS A 96 ? THR A 101 ? HIS A 96 THR A 101
A 4 VAL A 125 ? LYS A 129 ? VAL A 125 LYS A 129
A 5 GLY A 111 ? ALA A 113 ? GLY A 111 ALA A 113
#
loop_
_pdbx_struct_sheet_hbond.sheet_id
_pdbx_struct_sheet_hbond.range_id_1
_pdbx_struct_sheet_hbond.range_id_2
_pdbx_struct_sheet_hbond.range_1_label_atom_id
_pdbx_struct_sheet_hbond.range_1_label_comp_id
_pdbx_struct_sheet_hbond.range_1_label_asym_id
_pdbx_struct_sheet_hbond.range_1_label_seq_id
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code
_pdbx_struct_sheet_hbond.range_1_auth_atom_id
_pdbx_struct_sheet_hbond.range_1_auth_comp_id
_pdbx_struct_sheet_hbond.range_1_auth_asym_id
_pdbx_struct_sheet_hbond.range_1_auth_seq_id
_pdbx_struct_sheet_hbond.range_2_label_atom_id
_pdbx_struct_sheet_hbond.range_2_label_comp_id
_pdbx_struct_sheet_hbond.range_2_label_asym_id
_pdbx_struct_sheet_hbond.range_2_label_seq_id
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code
_pdbx_struct_sheet_hbond.range_2_auth_atom_id
_pdbx_struct_sheet_hbond.range_2_auth_comp_id
_pdbx_struct_sheet_hbond.range_2_auth_asym_id
_pdbx_struct_sheet_hbond.range_2_auth_seq_id
A 1 2 O THR A 54 ? O THR A 54 N LEU A 12 ? N LEU A 12
A 2 3 N VAL A 15 ? N VAL A 15 O LEU A 100 ? O LEU A 100
A 3 4 N LEU A 99 ? N LEU A 99 O VAL A 128 ? O VAL A 128
A 4 5 O VAL A 127 ? O VAL A 127 N TRP A 112 ? N TRP A 112
#
loop_
_struct_site.id
_struct_site.pdbx_evidence_code
_struct_site.pdbx_auth_asym_id
_struct_site.pdbx_auth_comp_id
_struct_site.pdbx_auth_seq_id
_struct_site.pdbx_auth_ins_code
_struct_site.pdbx_num_residues
_struct_site.details
AC1 Software A CD 981 ? 5 'BINDING SITE FOR RESIDUE CD A 981'
AC2 Software A CD 982 ? 5 'BINDING SITE FOR RESIDUE CD A 982'
AC3 Software A CD 983 ? 5 'BINDING SITE FOR RESIDUE CD A 983'
AC4 Software A CD 984 ? 4 'BINDING SITE FOR RESIDUE CD A 984'
AC5 Software A CD 985 ? 6 'BINDING SITE FOR RESIDUE CD A 985'
AC6 Software A CD 986 ? 3 'BINDING SITE FOR RESIDUE CD A 986'
AC7 Software A CD 987 ? 6 'BINDING SITE FOR RESIDUE CD A 987'
AC8 Software A CD 988 ? 5 'BINDING SITE FOR RESIDUE CD A 988'
AC9 Software A CD 989 ? 6 'BINDING SITE FOR RESIDUE CD A 989'
BC1 Software A CD 990 ? 6 'BINDING SITE FOR RESIDUE CD A 990'
BC2 Software A CD 991 ? 6 'BINDING SITE FOR RESIDUE CD A 991'
#
loop_
_struct_site_gen.id
_struct_site_gen.site_id
_struct_site_gen.pdbx_num_res
_struct_site_gen.label_comp_id
_struct_site_gen.label_asym_id
_struct_site_gen.label_seq_id
_struct_site_gen.pdbx_auth_ins_code
_struct_site_gen.auth_comp_id
_struct_site_gen.auth_asym_id
_struct_site_gen.auth_seq_id
_struct_site_gen.label_atom_id
_struct_site_gen.label_alt_id
_struct_site_gen.symmetry
_struct_site_gen.details
1 AC1 5 HIS A 144 ? HIS A 144 . ? 1_555 ?
2 AC1 5 HIS A 148 ? HIS A 148 . ? 1_555 ?
3 AC1 5 HIS A 154 ? HIS A 154 . ? 1_555 ?
4 AC1 5 TRP B 3 ? TRP B 253 . ? 1_555 ?
5 AC1 5 HOH O . ? HOH B 413 . ? 1_555 ?
6 AC2 5 HIS A 36 ? HIS A 36 . ? 1_555 ?
7 AC2 5 ASP A 156 ? ASP A 156 . ? 3_555 ?
8 AC2 5 ASP A 158 ? ASP A 158 . ? 3_555 ?
9 AC2 5 HOH N . ? HOH A 348 . ? 1_555 ?
10 AC2 5 HOH N . ? HOH A 349 . ? 1_555 ?
11 AC3 5 ASP A 181 ? ASP A 181 . ? 1_555 ?
12 AC3 5 ASP A 185 ? ASP A 185 . ? 1_555 ?
13 AC3 5 HOH N . ? HOH A 325 . ? 4_454 ?
14 AC3 5 HOH N . ? HOH A 431 . ? 1_555 ?
15 AC3 5 HOH N . ? HOH A 433 . ? 1_555 ?
16 AC4 4 HIS A 18 ? HIS A 18 . ? 1_555 ?
17 AC4 4 HOH N . ? HOH A 583 . ? 1_555 ?
18 AC4 4 HOH N . ? HOH A 721 . ? 1_555 ?
19 AC4 4 HOH N . ? HOH A 821 . ? 1_555 ?
20 AC5 6 GLN A 7 ? GLN A 7 . ? 1_555 ?
21 AC5 6 ASN A 50 ? ASN A 50 . ? 1_555 ?
22 AC5 6 HOH N . ? HOH A 319 . ? 1_555 ?
23 AC5 6 HOH N . ? HOH A 320 . ? 1_555 ?
24 AC5 6 HOH N . ? HOH A 438 . ? 1_555 ?
25 AC5 6 HOH N . ? HOH A 666 . ? 1_555 ?
26 AC6 3 ASP A 194 ? ASP A 194 . ? 1_555 ?
27 AC6 3 HOH N . ? HOH A 442 . ? 1_555 ?
28 AC6 3 HOH N . ? HOH A 571 . ? 1_555 ?
29 AC7 6 PRO A 203 ? PRO A 203 . ? 1_555 ?
30 AC7 6 HOH N . ? HOH A 392 . ? 3_555 ?
31 AC7 6 HOH N . ? HOH A 598 . ? 3_555 ?
32 AC7 6 HOH N . ? HOH A 746 . ? 1_555 ?
33 AC7 6 HOH N . ? HOH A 747 . ? 1_555 ?
34 AC7 6 HOH N . ? HOH A 837 . ? 1_555 ?
35 AC8 5 HIS A 131 ? HIS A 131 . ? 1_555 ?
36 AC8 5 HOH N . ? HOH A 354 . ? 1_555 ?
37 AC8 5 HOH N . ? HOH A 355 . ? 1_555 ?
38 AC8 5 HOH N . ? HOH A 356 . ? 1_555 ?
39 AC8 5 HOH N . ? HOH A 424 . ? 1_555 ?
40 AC9 6 HOH N . ? HOH A 380 . ? 1_555 ?
41 AC9 6 HOH N . ? HOH A 386 . ? 1_555 ?
42 AC9 6 HOH N . ? HOH A 550 . ? 1_555 ?
43 AC9 6 HOH N . ? HOH A 551 . ? 1_555 ?
44 AC9 6 HOH N . ? HOH A 552 . ? 1_555 ?
45 AC9 6 HOH N . ? HOH A 836 . ? 1_555 ?
46 BC1 6 GLU A 85 ? GLU A 85 . ? 8_555 ?
47 BC1 6 GLU A 85 ? GLU A 85 . ? 1_555 ?
48 BC1 6 HOH N . ? HOH A 617 . ? 8_555 ?
49 BC1 6 HOH N . ? HOH A 617 . ? 1_555 ?
50 BC1 6 HOH N . ? HOH A 618 . ? 1_555 ?
51 BC1 6 HOH N . ? HOH A 618 . ? 8_555 ?
52 BC2 6 GLU A 85 ? GLU A 85 . ? 8_555 ?
53 BC2 6 GLU A 85 ? GLU A 85 . ? 1_555 ?
54 BC2 6 GLU A 121 ? GLU A 121 . ? 1_555 ?
55 BC2 6 HOH N . ? HOH A 455 . ? 1_555 ?
56 BC2 6 HOH N . ? HOH A 803 . ? 8_555 ?
57 BC2 6 HOH N . ? HOH A 803 . ? 1_555 ?
#
_pdbx_entry_details.entry_id 1KUG
_pdbx_entry_details.compound_details ?
_pdbx_entry_details.source_details ?
_pdbx_entry_details.nonpolymer_details ?
_pdbx_entry_details.sequence_details ?
_pdbx_entry_details.has_ligand_of_interest ?
_pdbx_entry_details.has_protein_modification Y
#
loop_
_pdbx_validate_close_contact.id
_pdbx_validate_close_contact.PDB_model_num
_pdbx_validate_close_contact.auth_atom_id_1
_pdbx_validate_close_contact.auth_asym_id_1
_pdbx_validate_close_contact.auth_comp_id_1
_pdbx_validate_close_contact.auth_seq_id_1
_pdbx_validate_close_contact.PDB_ins_code_1
_pdbx_validate_close_contact.label_alt_id_1
_pdbx_validate_close_contact.auth_atom_id_2
_pdbx_validate_close_contact.auth_asym_id_2
_pdbx_validate_close_contact.auth_comp_id_2
_pdbx_validate_close_contact.auth_seq_id_2
_pdbx_validate_close_contact.PDB_ins_code_2
_pdbx_validate_close_contact.label_alt_id_2
_pdbx_validate_close_contact.dist
1 1 CD A CD 982 ? ? O A HOH 904 ? ? 0.60
2 1 O A HOH 341 ? ? O A HOH 827 ? ? 2.03
3 1 O A HOH 342 ? ? O A HOH 827 ? ? 2.08
4 1 O A HOH 441 ? ? O A HOH 844 ? ? 2.10
5 1 OE2 A GLU 11 ? ? O A HOH 341 ? ? 2.11
6 1 NH2 A ARG 47 ? ? O A HOH 822 ? ? 2.11
7 1 O A HOH 771 ? ? O A HOH 903 ? ? 2.16
8 1 O A HOH 351 ? ? O A HOH 472 ? ? 2.17
9 1 O A HOH 811 ? ? O A HOH 828 ? ? 2.18
10 1 O A HOH 667 ? ? O A HOH 824 ? ? 2.18
11 1 O A HOH 430 ? ? O A HOH 819 ? ? 2.18
#
loop_
_pdbx_validate_symm_contact.id
_pdbx_validate_symm_contact.PDB_model_num
_pdbx_validate_symm_contact.auth_atom_id_1
_pdbx_validate_symm_contact.auth_asym_id_1
_pdbx_validate_symm_contact.auth_comp_id_1
_pdbx_validate_symm_contact.auth_seq_id_1
_pdbx_validate_symm_contact.PDB_ins_code_1
_pdbx_validate_symm_contact.label_alt_id_1
_pdbx_validate_symm_contact.site_symmetry_1
_pdbx_validate_symm_contact.auth_atom_id_2
_pdbx_validate_symm_contact.auth_asym_id_2
_pdbx_validate_symm_contact.auth_comp_id_2
_pdbx_validate_symm_contact.auth_seq_id_2
_pdbx_validate_symm_contact.PDB_ins_code_2
_pdbx_validate_symm_contact.label_alt_id_2
_pdbx_validate_symm_contact.site_symmetry_2
_pdbx_validate_symm_contact.dist
1 1 OD2 A ASP 158 ? ? 1_555 O A HOH 904 ? ? 4_454 2.02
2 1 O A HOH 332 ? ? 1_555 O A HOH 822 ? ? 5_545 2.05
3 1 OD1 A ASP 156 ? ? 1_555 O A HOH 904 ? ? 4_454 2.07
4 1 O A HOH 693 ? ? 1_555 O A HOH 693 ? ? 8_555 2.12
5 1 OG1 A THR 68 ? ? 1_555 O A HOH 736 ? ? 5_545 2.13
#
loop_
_pdbx_validate_rmsd_angle.id
_pdbx_validate_rmsd_angle.PDB_model_num
_pdbx_validate_rmsd_angle.auth_atom_id_1
_pdbx_validate_rmsd_angle.auth_asym_id_1
_pdbx_validate_rmsd_angle.auth_comp_id_1
_pdbx_validate_rmsd_angle.auth_seq_id_1
_pdbx_validate_rmsd_angle.PDB_ins_code_1
_pdbx_validate_rmsd_angle.label_alt_id_1
_pdbx_validate_rmsd_angle.auth_atom_id_2
_pdbx_validate_rmsd_angle.auth_asym_id_2
_pdbx_validate_rmsd_angle.auth_comp_id_2
_pdbx_validate_rmsd_angle.auth_seq_id_2
_pdbx_validate_rmsd_angle.PDB_ins_code_2
_pdbx_validate_rmsd_angle.label_alt_id_2
_pdbx_validate_rmsd_angle.auth_atom_id_3
_pdbx_validate_rmsd_angle.auth_asym_id_3
_pdbx_validate_rmsd_angle.auth_comp_id_3
_pdbx_validate_rmsd_angle.auth_seq_id_3
_pdbx_validate_rmsd_angle.PDB_ins_code_3
_pdbx_validate_rmsd_angle.label_alt_id_3
_pdbx_validate_rmsd_angle.angle_value
_pdbx_validate_rmsd_angle.angle_target_value
_pdbx_validate_rmsd_angle.angle_deviation
_pdbx_validate_rmsd_angle.angle_standard_deviation
_pdbx_validate_rmsd_angle.linker_flag
1 1 CG A MET 137 ? ? SD A MET 137 ? ? CE A MET 137 ? ? 88.00 100.20 -12.20 1.60 N
2 1 CA A CYS 182 ? ? CB A CYS 182 ? ? SG A CYS 182 ? ? 121.90 114.20 7.70 1.10 N
#
loop_
_pdbx_validate_torsion.id
_pdbx_validate_torsion.PDB_model_num
_pdbx_validate_torsion.auth_comp_id
_pdbx_validate_torsion.auth_asym_id
_pdbx_validate_torsion.auth_seq_id
_pdbx_validate_torsion.PDB_ins_code
_pdbx_validate_torsion.label_alt_id
_pdbx_validate_torsion.phi
_pdbx_validate_torsion.psi
1 1 TYR A 24 ? ? -95.96 39.61
2 1 CYS A 119 ? ? 86.49 -16.96
#
_pdbx_struct_mod_residue.id 1
_pdbx_struct_mod_residue.label_asym_id B
_pdbx_struct_mod_residue.label_comp_id PCA
_pdbx_struct_mod_residue.label_seq_id 1
_pdbx_struct_mod_residue.auth_asym_id B
_pdbx_struct_mod_residue.auth_comp_id PCA
_pdbx_struct_mod_residue.auth_seq_id 251
_pdbx_struct_mod_residue.PDB_ins_code ?
_pdbx_struct_mod_residue.parent_comp_id GLN
_pdbx_struct_mod_residue.details 'PYROGLUTAMIC ACID'
#
loop_
_pdbx_struct_special_symmetry.id
_pdbx_struct_special_symmetry.PDB_model_num
_pdbx_struct_special_symmetry.auth_asym_id
_pdbx_struct_special_symmetry.auth_comp_id
_pdbx_struct_special_symmetry.auth_seq_id
_pdbx_struct_special_symmetry.PDB_ins_code
_pdbx_struct_special_symmetry.label_asym_id
_pdbx_struct_special_symmetry.label_comp_id
_pdbx_struct_special_symmetry.label_seq_id
1 1 A CD 990 ? L CD .
2 1 A HOH 617 ? N HOH .
3 1 B HOH 853 ? O HOH .
#
loop_
_pdbx_unobs_or_zero_occ_residues.id
_pdbx_unobs_or_zero_occ_residues.PDB_model_num
_pdbx_unobs_or_zero_occ_residues.polymer_flag
_pdbx_unobs_or_zero_occ_residues.occupancy_flag
_pdbx_unobs_or_zero_occ_residues.auth_asym_id
_pdbx_unobs_or_zero_occ_residues.auth_comp_id
_pdbx_unobs_or_zero_occ_residues.auth_seq_id
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code
_pdbx_unobs_or_zero_occ_residues.label_asym_id
_pdbx_unobs_or_zero_occ_residues.label_comp_id
_pdbx_unobs_or_zero_occ_residues.label_seq_id
1 1 Y 1 A GLU 1 ? A GLU 1
2 1 Y 1 A GLN 2 ? A GLN 2
#
loop_
_chem_comp_atom.comp_id
_chem_comp_atom.atom_id
_chem_comp_atom.type_symbol
_chem_comp_atom.pdbx_aromatic_flag
_chem_comp_atom.pdbx_stereo_config
_chem_comp_atom.pdbx_ordinal
ALA N N N N 1
ALA CA C N S 2
ALA C C N N 3
ALA O O N N 4
ALA CB C N N 5
ALA OXT O N N 6
ALA H H N N 7
ALA H2 H N N 8
ALA HA H N N 9
ALA HB1 H N N 10
ALA HB2 H N N 11
ALA HB3 H N N 12
ALA HXT H N N 13
ARG N N N N 14
ARG CA C N S 15
ARG C C N N 16
ARG O O N N 17
ARG CB C N N 18
ARG CG C N N 19
ARG CD C N N 20
ARG NE N N N 21
ARG CZ C N N 22
ARG NH1 N N N 23
ARG NH2 N N N 24
ARG OXT O N N 25
ARG H H N N 26
ARG H2 H N N 27
ARG HA H N N 28
ARG HB2 H N N 29
ARG HB3 H N N 30
ARG HG2 H N N 31
ARG HG3 H N N 32
ARG HD2 H N N 33
ARG HD3 H N N 34
ARG HE H N N 35
ARG HH11 H N N 36
ARG HH12 H N N 37
ARG HH21 H N N 38
ARG HH22 H N N 39
ARG HXT H N N 40
ASN N N N N 41
ASN CA C N S 42
ASN C C N N 43
ASN O O N N 44
ASN CB C N N 45
ASN CG C N N 46
ASN OD1 O N N 47
ASN ND2 N N N 48
ASN OXT O N N 49
ASN H H N N 50
ASN H2 H N N 51
ASN HA H N N 52
ASN HB2 H N N 53
ASN HB3 H N N 54
ASN HD21 H N N 55
ASN HD22 H N N 56
ASN HXT H N N 57
ASP N N N N 58
ASP CA C N S 59
ASP C C N N 60
ASP O O N N 61
ASP CB C N N 62
ASP CG C N N 63
ASP OD1 O N N 64
ASP OD2 O N N 65
ASP OXT O N N 66
ASP H H N N 67
ASP H2 H N N 68
ASP HA H N N 69
ASP HB2 H N N 70
ASP HB3 H N N 71
ASP HD2 H N N 72
ASP HXT H N N 73
CD CD CD N N 74
CYS N N N N 75
CYS CA C N R 76
CYS C C N N 77
CYS O O N N 78
CYS CB C N N 79
CYS SG S N N 80
CYS OXT O N N 81
CYS H H N N 82
CYS H2 H N N 83
CYS HA H N N 84
CYS HB2 H N N 85
CYS HB3 H N N 86
CYS HG H N N 87
CYS HXT H N N 88
GLN N N N N 89
GLN CA C N S 90
GLN C C N N 91
GLN O O N N 92
GLN CB C N N 93
GLN CG C N N 94
GLN CD C N N 95
GLN OE1 O N N 96
GLN NE2 N N N 97
GLN OXT O N N 98
GLN H H N N 99
GLN H2 H N N 100
GLN HA H N N 101
GLN HB2 H N N 102
GLN HB3 H N N 103
GLN HG2 H N N 104
GLN HG3 H N N 105
GLN HE21 H N N 106
GLN HE22 H N N 107
GLN HXT H N N 108
GLU N N N N 109
GLU CA C N S 110
GLU C C N N 111
GLU O O N N 112
GLU CB C N N 113
GLU CG C N N 114
GLU CD C N N 115
GLU OE1 O N N 116
GLU OE2 O N N 117
GLU OXT O N N 118
GLU H H N N 119
GLU H2 H N N 120
GLU HA H N N 121
GLU HB2 H N N 122
GLU HB3 H N N 123
GLU HG2 H N N 124
GLU HG3 H N N 125
GLU HE2 H N N 126
GLU HXT H N N 127
GLY N N N N 128
GLY CA C N N 129
GLY C C N N 130
GLY O O N N 131
GLY OXT O N N 132
GLY H H N N 133
GLY H2 H N N 134
GLY HA2 H N N 135
GLY HA3 H N N 136
GLY HXT H N N 137
HIS N N N N 138
HIS CA C N S 139
HIS C C N N 140
HIS O O N N 141
HIS CB C N N 142
HIS CG C Y N 143
HIS ND1 N Y N 144
HIS CD2 C Y N 145
HIS CE1 C Y N 146
HIS NE2 N Y N 147
HIS OXT O N N 148
HIS H H N N 149
HIS H2 H N N 150
HIS HA H N N 151
HIS HB2 H N N 152
HIS HB3 H N N 153
HIS HD1 H N N 154
HIS HD2 H N N 155
HIS HE1 H N N 156
HIS HE2 H N N 157
HIS HXT H N N 158
HOH O O N N 159
HOH H1 H N N 160
HOH H2 H N N 161
ILE N N N N 162
ILE CA C N S 163
ILE C C N N 164
ILE O O N N 165
ILE CB C N S 166
ILE CG1 C N N 167
ILE CG2 C N N 168
ILE CD1 C N N 169
ILE OXT O N N 170
ILE H H N N 171
ILE H2 H N N 172
ILE HA H N N 173
ILE HB H N N 174
ILE HG12 H N N 175
ILE HG13 H N N 176
ILE HG21 H N N 177
ILE HG22 H N N 178
ILE HG23 H N N 179
ILE HD11 H N N 180
ILE HD12 H N N 181
ILE HD13 H N N 182
ILE HXT H N N 183
LEU N N N N 184
LEU CA C N S 185
LEU C C N N 186
LEU O O N N 187
LEU CB C N N 188
LEU CG C N N 189
LEU CD1 C N N 190
LEU CD2 C N N 191
LEU OXT O N N 192
LEU H H N N 193
LEU H2 H N N 194
LEU HA H N N 195
LEU HB2 H N N 196
LEU HB3 H N N 197
LEU HG H N N 198
LEU HD11 H N N 199
LEU HD12 H N N 200
LEU HD13 H N N 201
LEU HD21 H N N 202
LEU HD22 H N N 203
LEU HD23 H N N 204
LEU HXT H N N 205
LYS N N N N 206
LYS CA C N S 207
LYS C C N N 208
LYS O O N N 209
LYS CB C N N 210
LYS CG C N N 211
LYS CD C N N 212
LYS CE C N N 213
LYS NZ N N N 214
LYS OXT O N N 215
LYS H H N N 216
LYS H2 H N N 217
LYS HA H N N 218
LYS HB2 H N N 219
LYS HB3 H N N 220
LYS HG2 H N N 221
LYS HG3 H N N 222
LYS HD2 H N N 223
LYS HD3 H N N 224
LYS HE2 H N N 225
LYS HE3 H N N 226
LYS HZ1 H N N 227
LYS HZ2 H N N 228
LYS HZ3 H N N 229
LYS HXT H N N 230
MET N N N N 231
MET CA C N S 232
MET C C N N 233
MET O O N N 234
MET CB C N N 235
MET CG C N N 236
MET SD S N N 237
MET CE C N N 238
MET OXT O N N 239
MET H H N N 240
MET H2 H N N 241
MET HA H N N 242
MET HB2 H N N 243
MET HB3 H N N 244
MET HG2 H N N 245
MET HG3 H N N 246
MET HE1 H N N 247
MET HE2 H N N 248
MET HE3 H N N 249
MET HXT H N N 250
PCA N N N N 251
PCA CA C N S 252
PCA CB C N N 253
PCA CG C N N 254
PCA CD C N N 255
PCA OE O N N 256
PCA C C N N 257
PCA O O N N 258
PCA OXT O N N 259
PCA H H N N 260
PCA HA H N N 261
PCA HB2 H N N 262
PCA HB3 H N N 263
PCA HG2 H N N 264
PCA HG3 H N N 265
PCA HXT H N N 266
PHE N N N N 267
PHE CA C N S 268
PHE C C N N 269
PHE O O N N 270
PHE CB C N N 271
PHE CG C Y N 272
PHE CD1 C Y N 273
PHE CD2 C Y N 274
PHE CE1 C Y N 275
PHE CE2 C Y N 276
PHE CZ C Y N 277
PHE OXT O N N 278
PHE H H N N 279
PHE H2 H N N 280
PHE HA H N N 281
PHE HB2 H N N 282
PHE HB3 H N N 283
PHE HD1 H N N 284
PHE HD2 H N N 285
PHE HE1 H N N 286
PHE HE2 H N N 287
PHE HZ H N N 288
PHE HXT H N N 289
PRO N N N N 290
PRO CA C N S 291
PRO C C N N 292
PRO O O N N 293
PRO CB C N N 294
PRO CG C N N 295
PRO CD C N N 296
PRO OXT O N N 297
PRO H H N N 298
PRO HA H N N 299
PRO HB2 H N N 300
PRO HB3 H N N 301
PRO HG2 H N N 302
PRO HG3 H N N 303
PRO HD2 H N N 304
PRO HD3 H N N 305
PRO HXT H N N 306
SER N N N N 307
SER CA C N S 308
SER C C N N 309
SER O O N N 310
SER CB C N N 311
SER OG O N N 312
SER OXT O N N 313
SER H H N N 314
SER H2 H N N 315
SER HA H N N 316
SER HB2 H N N 317
SER HB3 H N N 318
SER HG H N N 319
SER HXT H N N 320
THR N N N N 321
THR CA C N S 322
THR C C N N 323
THR O O N N 324
THR CB C N R 325
THR OG1 O N N 326
THR CG2 C N N 327
THR OXT O N N 328
THR H H N N 329
THR H2 H N N 330
THR HA H N N 331
THR HB H N N 332
THR HG1 H N N 333
THR HG21 H N N 334
THR HG22 H N N 335
THR HG23 H N N 336
THR HXT H N N 337
TRP N N N N 338
TRP CA C N S 339
TRP C C N N 340
TRP O O N N 341
TRP CB C N N 342
TRP CG C Y N 343
TRP CD1 C Y N 344
TRP CD2 C Y N 345
TRP NE1 N Y N 346
TRP CE2 C Y N 347
TRP CE3 C Y N 348
TRP CZ2 C Y N 349
TRP CZ3 C Y N 350
TRP CH2 C Y N 351
TRP OXT O N N 352
TRP H H N N 353
TRP H2 H N N 354
TRP HA H N N 355
TRP HB2 H N N 356
TRP HB3 H N N 357
TRP HD1 H N N 358
TRP HE1 H N N 359
TRP HE3 H N N 360
TRP HZ2 H N N 361
TRP HZ3 H N N 362
TRP HH2 H N N 363
TRP HXT H N N 364
TYR N N N N 365
TYR CA C N S 366
TYR C C N N 367
TYR O O N N 368
TYR CB C N N 369
TYR CG C Y N 370
TYR CD1 C Y N 371
TYR CD2 C Y N 372
TYR CE1 C Y N 373
TYR CE2 C Y N 374
TYR CZ C Y N 375
TYR OH O N N 376
TYR OXT O N N 377
TYR H H N N 378
TYR H2 H N N 379
TYR HA H N N 380
TYR HB2 H N N 381
TYR HB3 H N N 382
TYR HD1 H N N 383
TYR HD2 H N N 384
TYR HE1 H N N 385
TYR HE2 H N N 386
TYR HH H N N 387
TYR HXT H N N 388
VAL N N N N 389
VAL CA C N S 390
VAL C C N N 391
VAL O O N N 392
VAL CB C N N 393
VAL CG1 C N N 394
VAL CG2 C N N 395
VAL OXT O N N 396
VAL H H N N 397
VAL H2 H N N 398
VAL HA H N N 399
VAL HB H N N 400
VAL HG11 H N N 401
VAL HG12 H N N 402
VAL HG13 H N N 403
VAL HG21 H N N 404
VAL HG22 H N N 405
VAL HG23 H N N 406
VAL HXT H N N 407
#
loop_
_chem_comp_bond.comp_id
_chem_comp_bond.atom_id_1
_chem_comp_bond.atom_id_2
_chem_comp_bond.value_order
_chem_comp_bond.pdbx_aromatic_flag
_chem_comp_bond.pdbx_stereo_config
_chem_comp_bond.pdbx_ordinal
ALA N CA SING N N 1
ALA N H SING N N 2
ALA N H2 SING N N 3
ALA CA C SING N N 4
ALA CA CB SING N N 5
ALA CA HA SING N N 6
ALA C O DOUB N N 7
ALA C OXT SING N N 8
ALA CB HB1 SING N N 9
ALA CB HB2 SING N N 10
ALA CB HB3 SING N N 11
ALA OXT HXT SING N N 12
ARG N CA SING N N 1
ARG N H SING N N 2
ARG N H2 SING N N 3
ARG CA C SING N N 4
ARG CA CB SING N N 5
ARG CA HA SING N N 6
ARG C O DOUB N N 7
ARG C OXT SING N N 8
ARG CB CG SING N N 9
ARG CB HB2 SING N N 10
ARG CB HB3 SING N N 11
ARG CG CD SING N N 12
ARG CG HG2 SING N N 13
ARG CG HG3 SING N N 14
ARG CD NE SING N N 15
ARG CD HD2 SING N N 16
ARG CD HD3 SING N N 17
ARG NE CZ SING N N 18
ARG NE HE SING N N 19
ARG CZ NH1 SING N N 20
ARG CZ NH2 DOUB N N 21
ARG NH1 HH11 SING N N 22
ARG NH1 HH12 SING N N 23
ARG NH2 HH21 SING N N 24
ARG NH2 HH22 SING N N 25
ARG OXT HXT SING N N 26
ASN N CA SING N N 1
ASN N H SING N N 2
ASN N H2 SING N N 3
ASN CA C SING N N 4
ASN CA CB SING N N 5
ASN CA HA SING N N 6
ASN C O DOUB N N 7
ASN C OXT SING N N 8
ASN CB CG SING N N 9
ASN CB HB2 SING N N 10
ASN CB HB3 SING N N 11
ASN CG OD1 DOUB N N 12
ASN CG ND2 SING N N 13
ASN ND2 HD21 SING N N 14
ASN ND2 HD22 SING N N 15
ASN OXT HXT SING N N 16
ASP N CA SING N N 1
ASP N H SING N N 2
ASP N H2 SING N N 3
ASP CA C SING N N 4
ASP CA CB SING N N 5
ASP CA HA SING N N 6
ASP C O DOUB N N 7
ASP C OXT SING N N 8
ASP CB CG SING N N 9
ASP CB HB2 SING N N 10
ASP CB HB3 SING N N 11
ASP CG OD1 DOUB N N 12
ASP CG OD2 SING N N 13
ASP OD2 HD2 SING N N 14
ASP OXT HXT SING N N 15
CYS N CA SING N N 1
CYS N H SING N N 2
CYS N H2 SING N N 3
CYS CA C SING N N 4
CYS CA CB SING N N 5
CYS CA HA SING N N 6
CYS C O DOUB N N 7
CYS C OXT SING N N 8
CYS CB SG SING N N 9
CYS CB HB2 SING N N 10
CYS CB HB3 SING N N 11
CYS SG HG SING N N 12
CYS OXT HXT SING N N 13
GLN N CA SING N N 1
GLN N H SING N N 2
GLN N H2 SING N N 3
GLN CA C SING N N 4
GLN CA CB SING N N 5
GLN CA HA SING N N 6
GLN C O DOUB N N 7
GLN C OXT SING N N 8
GLN CB CG SING N N 9
GLN CB HB2 SING N N 10
GLN CB HB3 SING N N 11
GLN CG CD SING N N 12
GLN CG HG2 SING N N 13
GLN CG HG3 SING N N 14
GLN CD OE1 DOUB N N 15
GLN CD NE2 SING N N 16
GLN NE2 HE21 SING N N 17
GLN NE2 HE22 SING N N 18
GLN OXT HXT SING N N 19
GLU N CA SING N N 1
GLU N H SING N N 2
GLU N H2 SING N N 3
GLU CA C SING N N 4
GLU CA CB SING N N 5
GLU CA HA SING N N 6
GLU C O DOUB N N 7
GLU C OXT SING N N 8
GLU CB CG SING N N 9
GLU CB HB2 SING N N 10
GLU CB HB3 SING N N 11
GLU CG CD SING N N 12
GLU CG HG2 SING N N 13
GLU CG HG3 SING N N 14
GLU CD OE1 DOUB N N 15
GLU CD OE2 SING N N 16
GLU OE2 HE2 SING N N 17
GLU OXT HXT SING N N 18
GLY N CA SING N N 1
GLY N H SING N N 2
GLY N H2 SING N N 3
GLY CA C SING N N 4
GLY CA HA2 SING N N 5
GLY CA HA3 SING N N 6
GLY C O DOUB N N 7
GLY C OXT SING N N 8
GLY OXT HXT SING N N 9
HIS N CA SING N N 1
HIS N H SING N N 2
HIS N H2 SING N N 3
HIS CA C SING N N 4
HIS CA CB SING N N 5
HIS CA HA SING N N 6
HIS C O DOUB N N 7
HIS C OXT SING N N 8
HIS CB CG SING N N 9
HIS CB HB2 SING N N 10
HIS CB HB3 SING N N 11
HIS CG ND1 SING Y N 12
HIS CG CD2 DOUB Y N 13
HIS ND1 CE1 DOUB Y N 14
HIS ND1 HD1 SING N N 15
HIS CD2 NE2 SING Y N 16
HIS CD2 HD2 SING N N 17
HIS CE1 NE2 SING Y N 18
HIS CE1 HE1 SING N N 19
HIS NE2 HE2 SING N N 20
HIS OXT HXT SING N N 21
HOH O H1 SING N N 1
HOH O H2 SING N N 2
ILE N CA SING N N 1
ILE N H SING N N 2
ILE N H2 SING N N 3
ILE CA C SING N N 4
ILE CA CB SING N N 5
ILE CA HA SING N N 6
ILE C O DOUB N N 7
ILE C OXT SING N N 8
ILE CB CG1 SING N N 9
ILE CB CG2 SING N N 10
ILE CB HB SING N N 11
ILE CG1 CD1 SING N N 12
ILE CG1 HG12 SING N N 13
ILE CG1 HG13 SING N N 14
ILE CG2 HG21 SING N N 15
ILE CG2 HG22 SING N N 16
ILE CG2 HG23 SING N N 17
ILE CD1 HD11 SING N N 18
ILE CD1 HD12 SING N N 19
ILE CD1 HD13 SING N N 20
ILE OXT HXT SING N N 21
LEU N CA SING N N 1
LEU N H SING N N 2
LEU N H2 SING N N 3
LEU CA C SING N N 4
LEU CA CB SING N N 5
LEU CA HA SING N N 6
LEU C O DOUB N N 7
LEU C OXT SING N N 8
LEU CB CG SING N N 9
LEU CB HB2 SING N N 10
LEU CB HB3 SING N N 11
LEU CG CD1 SING N N 12
LEU CG CD2 SING N N 13
LEU CG HG SING N N 14
LEU CD1 HD11 SING N N 15
LEU CD1 HD12 SING N N 16
LEU CD1 HD13 SING N N 17
LEU CD2 HD21 SING N N 18
LEU CD2 HD22 SING N N 19
LEU CD2 HD23 SING N N 20
LEU OXT HXT SING N N 21
LYS N CA SING N N 1
LYS N H SING N N 2
LYS N H2 SING N N 3
LYS CA C SING N N 4
LYS CA CB SING N N 5
LYS CA HA SING N N 6
LYS C O DOUB N N 7
LYS C OXT SING N N 8
LYS CB CG SING N N 9
LYS CB HB2 SING N N 10
LYS CB HB3 SING N N 11
LYS CG CD SING N N 12
LYS CG HG2 SING N N 13
LYS CG HG3 SING N N 14
LYS CD CE SING N N 15
LYS CD HD2 SING N N 16
LYS CD HD3 SING N N 17
LYS CE NZ SING N N 18
LYS CE HE2 SING N N 19
LYS CE HE3 SING N N 20
LYS NZ HZ1 SING N N 21
LYS NZ HZ2 SING N N 22
LYS NZ HZ3 SING N N 23
LYS OXT HXT SING N N 24
MET N CA SING N N 1
MET N H SING N N 2
MET N H2 SING N N 3
MET CA C SING N N 4
MET CA CB SING N N 5
MET CA HA SING N N 6
MET C O DOUB N N 7
MET C OXT SING N N 8
MET CB CG SING N N 9
MET CB HB2 SING N N 10
MET CB HB3 SING N N 11
MET CG SD SING N N 12
MET CG HG2 SING N N 13
MET CG HG3 SING N N 14
MET SD CE SING N N 15
MET CE HE1 SING N N 16
MET CE HE2 SING N N 17
MET CE HE3 SING N N 18
MET OXT HXT SING N N 19
PCA N CA SING N N 1
PCA N CD SING N N 2
PCA N H SING N N 3
PCA CA CB SING N N 4
PCA CA C SING N N 5
PCA CA HA SING N N 6
PCA CB CG SING N N 7
PCA CB HB2 SING N N 8
PCA CB HB3 SING N N 9
PCA CG CD SING N N 10
PCA CG HG2 SING N N 11
PCA CG HG3 SING N N 12
PCA CD OE DOUB N N 13
PCA C O DOUB N N 14
PCA C OXT SING N N 15
PCA OXT HXT SING N N 16
PHE N CA SING N N 1
PHE N H SING N N 2
PHE N H2 SING N N 3
PHE CA C SING N N 4
PHE CA CB SING N N 5
PHE CA HA SING N N 6
PHE C O DOUB N N 7
PHE C OXT SING N N 8
PHE CB CG SING N N 9
PHE CB HB2 SING N N 10
PHE CB HB3 SING N N 11
PHE CG CD1 DOUB Y N 12
PHE CG CD2 SING Y N 13
PHE CD1 CE1 SING Y N 14
PHE CD1 HD1 SING N N 15
PHE CD2 CE2 DOUB Y N 16
PHE CD2 HD2 SING N N 17
PHE CE1 CZ DOUB Y N 18
PHE CE1 HE1 SING N N 19
PHE CE2 CZ SING Y N 20
PHE CE2 HE2 SING N N 21
PHE CZ HZ SING N N 22
PHE OXT HXT SING N N 23
PRO N CA SING N N 1
PRO N CD SING N N 2
PRO N H SING N N 3
PRO CA C SING N N 4
PRO CA CB SING N N 5
PRO CA HA SING N N 6
PRO C O DOUB N N 7
PRO C OXT SING N N 8
PRO CB CG SING N N 9
PRO CB HB2 SING N N 10
PRO CB HB3 SING N N 11
PRO CG CD SING N N 12
PRO CG HG2 SING N N 13
PRO CG HG3 SING N N 14
PRO CD HD2 SING N N 15
PRO CD HD3 SING N N 16
PRO OXT HXT SING N N 17
SER N CA SING N N 1
SER N H SING N N 2
SER N H2 SING N N 3
SER CA C SING N N 4
SER CA CB SING N N 5
SER CA HA SING N N 6
SER C O DOUB N N 7
SER C OXT SING N N 8
SER CB OG SING N N 9
SER CB HB2 SING N N 10
SER CB HB3 SING N N 11
SER OG HG SING N N 12
SER OXT HXT SING N N 13
THR N CA SING N N 1
THR N H SING N N 2
THR N H2 SING N N 3
THR CA C SING N N 4
THR CA CB SING N N 5
THR CA HA SING N N 6
THR C O DOUB N N 7
THR C OXT SING N N 8
THR CB OG1 SING N N 9
THR CB CG2 SING N N 10
THR CB HB SING N N 11
THR OG1 HG1 SING N N 12
THR CG2 HG21 SING N N 13
THR CG2 HG22 SING N N 14
THR CG2 HG23 SING N N 15
THR OXT HXT SING N N 16
TRP N CA SING N N 1
TRP N H SING N N 2
TRP N H2 SING N N 3
TRP CA C SING N N 4
TRP CA CB SING N N 5
TRP CA HA SING N N 6
TRP C O DOUB N N 7
TRP C OXT SING N N 8
TRP CB CG SING N N 9
TRP CB HB2 SING N N 10
TRP CB HB3 SING N N 11
TRP CG CD1 DOUB Y N 12
TRP CG CD2 SING Y N 13
TRP CD1 NE1 SING Y N 14
TRP CD1 HD1 SING N N 15
TRP CD2 CE2 DOUB Y N 16
TRP CD2 CE3 SING Y N 17
TRP NE1 CE2 SING Y N 18
TRP NE1 HE1 SING N N 19
TRP CE2 CZ2 SING Y N 20
TRP CE3 CZ3 DOUB Y N 21
TRP CE3 HE3 SING N N 22
TRP CZ2 CH2 DOUB Y N 23
TRP CZ2 HZ2 SING N N 24
TRP CZ3 CH2 SING Y N 25
TRP CZ3 HZ3 SING N N 26
TRP CH2 HH2 SING N N 27
TRP OXT HXT SING N N 28
TYR N CA SING N N 1
TYR N H SING N N 2
TYR N H2 SING N N 3
TYR CA C SING N N 4
TYR CA CB SING N N 5
TYR CA HA SING N N 6
TYR C O DOUB N N 7
TYR C OXT SING N N 8
TYR CB CG SING N N 9
TYR CB HB2 SING N N 10
TYR CB HB3 SING N N 11
TYR CG CD1 DOUB Y N 12
TYR CG CD2 SING Y N 13
TYR CD1 CE1 SING Y N 14
TYR CD1 HD1 SING N N 15
TYR CD2 CE2 DOUB Y N 16
TYR CD2 HD2 SING N N 17
TYR CE1 CZ DOUB Y N 18
TYR CE1 HE1 SING N N 19
TYR CE2 CZ SING Y N 20
TYR CE2 HE2 SING N N 21
TYR CZ OH SING N N 22
TYR OH HH SING N N 23
TYR OXT HXT SING N N 24
VAL N CA SING N N 1
VAL N H SING N N 2
VAL N H2 SING N N 3
VAL CA C SING N N 4
VAL CA CB SING N N 5
VAL CA HA SING N N 6
VAL C O DOUB N N 7
VAL C OXT SING N N 8
VAL CB CG1 SING N N 9
VAL CB CG2 SING N N 10
VAL CB HB SING N N 11
VAL CG1 HG11 SING N N 12
VAL CG1 HG12 SING N N 13
VAL CG1 HG13 SING N N 14
VAL CG2 HG21 SING N N 15
VAL CG2 HG22 SING N N 16
VAL CG2 HG23 SING N N 17
VAL OXT HXT SING N N 18
#
_atom_sites.entry_id 1KUG
_atom_sites.fract_transf_matrix[1][1] 0.016353
_atom_sites.fract_transf_matrix[1][2] 0.000000
_atom_sites.fract_transf_matrix[1][3] 0.000000
_atom_sites.fract_transf_matrix[2][1] 0.000000
_atom_sites.fract_transf_matrix[2][2] 0.016353
_atom_sites.fract_transf_matrix[2][3] 0.000000
_atom_sites.fract_transf_matrix[3][1] 0.000000
_atom_sites.fract_transf_matrix[3][2] 0.000000
_atom_sites.fract_transf_matrix[3][3] 0.007622
_atom_sites.fract_transf_vector[1] 0.00000
_atom_sites.fract_transf_vector[2] 0.00000
_atom_sites.fract_transf_vector[3] 0.00000
#
loop_
_atom_type.symbol
C
CD
N
O
S
#
loop_
_atom_site.group_PDB
_atom_site.id
_atom_site.type_symbol
_atom_site.label_atom_id
_atom_site.label_alt_id
_atom_site.label_comp_id
_atom_site.label_asym_id
_atom_site.label_entity_id
_atom_site.label_seq_id
_atom_site.pdbx_PDB_ins_code
_atom_site.Cartn_x
_atom_site.Cartn_y
_atom_site.Cartn_z
_atom_site.occupancy
_atom_site.B_iso_or_equiv
_atom_site.pdbx_formal_charge
_atom_site.auth_seq_id
_atom_site.auth_comp_id
_atom_site.auth_asym_id
_atom_site.auth_atom_id
_atom_site.pdbx_PDB_model_num
_atom_site.pdbx_label_index
_atom_site.pdbx_sifts_xref_db_name
_atom_site.pdbx_sifts_xref_db_acc
_atom_site.pdbx_sifts_xref_db_num
_atom_site.pdbx_sifts_xref_db_res
ATOM 1 N N . GLN A 1 3 ? -5.117 37.400 14.327 1.00 24.85 ? 3 GLN A N 1 3 UNP O57413 192 Q
ATOM 2 C CA . GLN A 1 3 ? -4.630 35.987 14.445 1.00 23.16 ? 3 GLN A CA 1 3 UNP O57413 192 Q
ATOM 3 C C . GLN A 1 3 ? -5.692 35.066 13.850 1.00 21.60 ? 3 GLN A C 1 3 UNP O57413 192 Q
ATOM 4 O O . GLN A 1 3 ? -6.877 35.140 14.204 1.00 22.03 ? 3 GLN A O 1 3 UNP O57413 192 Q
ATOM 5 C CB . GLN A 1 3 ? -4.395 35.613 15.919 1.00 25.04 ? 3 GLN A CB 1 3 UNP O57413 192 Q
ATOM 6 C CG . GLN A 1 3 ? -3.618 34.324 16.133 1.00 27.62 ? 3 GLN A CG 1 3 UNP O57413 192 Q
ATOM 7 C CD . GLN A 1 3 ? -2.107 34.541 16.237 1.00 28.62 ? 3 GLN A CD 1 3 UNP O57413 192 Q
ATOM 8 O OE1 . GLN A 1 3 ? -1.314 33.948 15.487 1.00 29.88 ? 3 GLN A OE1 1 3 UNP O57413 192 Q
ATOM 9 N NE2 . GLN A 1 3 ? -1.702 35.385 17.179 1.00 29.15 ? 3 GLN A NE2 1 3 UNP O57413 192 Q
ATOM 10 N N . ARG A 1 4 ? -5.264 34.184 12.957 1.00 18.38 ? 4 ARG A N 1 4 UNP O57413 193 R
ATOM 11 C CA . ARG A 1 4 ? -6.183 33.257 12.323 1.00 15.70 ? 4 ARG A CA 1 4 UNP O57413 193 R
ATOM 12 C C . ARG A 1 4 ? -6.746 32.194 13.260 1.00 14.39 ? 4 ARG A C 1 4 UNP O57413 193 R
ATOM 13 O O . ARG A 1 4 ? -7.892 31.769 13.114 1.00 15.10 ? 4 ARG A O 1 4 UNP O57413 193 R
ATOM 14 C CB . ARG A 1 4 ? -5.490 32.592 11.142 1.00 14.42 ? 4 ARG A CB 1 4 UNP O57413 193 R
ATOM 15 C CG . ARG A 1 4 ? -6.236 31.402 10.586 1.00 14.50 ? 4 ARG A CG 1 4 UNP O57413 193 R
ATOM 16 C CD . ARG A 1 4 ? -5.589 30.875 9.330 1.00 14.24 ? 4 ARG A CD 1 4 UNP O57413 193 R
ATOM 17 N NE . ARG A 1 4 ? -6.325 29.702 8.863 1.00 14.75 ? 4 ARG A NE 1 4 UNP O57413 193 R
ATOM 18 C CZ . ARG A 1 4 ? -6.030 29.002 7.777 1.00 13.75 ? 4 ARG A CZ 1 4 UNP O57413 193 R
ATOM 19 N NH1 . ARG A 1 4 ? -5.006 29.362 7.007 1.00 15.06 ? 4 ARG A NH1 1 4 UNP O57413 193 R
ATOM 20 N NH2 . ARG A 1 4 ? -6.730 27.902 7.505 1.00 14.42 ? 4 ARG A NH2 1 4 UNP O57413 193 R
ATOM 21 N N . PHE A 1 5 ? -5.956 31.764 14.242 1.00 11.86 ? 5 PHE A N 1 5 UNP O57413 194 F
ATOM 22 C CA . PHE A 1 5 ? -6.384 30.730 15.165 1.00 11.14 ? 5 PHE A CA 1 5 UNP O57413 194 F
ATOM 23 C C . PHE A 1 5 ? -6.542 31.211 16.594 1.00 10.70 ? 5 PHE A C 1 5 UNP O57413 194 F
ATOM 24 O O . PHE A 1 5 ? -5.840 32.101 17.022 1.00 10.62 ? 5 PHE A O 1 5 UNP O57413 194 F
ATOM 25 C CB . PHE A 1 5 ? -5.346 29.578 15.149 1.00 9.79 ? 5 PHE A CB 1 5 UNP O57413 194 F
ATOM 26 C CG . PHE A 1 5 ? -5.255 28.878 13.827 1.00 8.40 ? 5 PHE A CG 1 5 UNP O57413 194 F
ATOM 27 C CD1 . PHE A 1 5 ? -4.181 29.088 12.974 1.00 9.21 ? 5 PHE A CD1 1 5 UNP O57413 194 F
ATOM 28 C CD2 . PHE A 1 5 ? -6.281 28.044 13.418 1.00 8.88 ? 5 PHE A CD2 1 5 UNP O57413 194 F
ATOM 29 C CE1 . PHE A 1 5 ? -4.130 28.472 11.731 1.00 8.69 ? 5 PHE A CE1 1 5 UNP O57413 194 F
ATOM 30 C CE2 . PHE A 1 5 ? -6.231 27.433 12.187 1.00 9.07 ? 5 PHE A CE2 1 5 UNP O57413 194 F
ATOM 31 C CZ . PHE A 1 5 ? -5.147 27.654 11.350 1.00 8.86 ? 5 PHE A CZ 1 5 UNP O57413 194 F
ATOM 32 N N . PRO A 1 6 ? -7.464 30.602 17.345 1.00 11.90 ? 6 PRO A N 1 6 UNP O57413 195 P
ATOM 33 C CA . PRO A 1 6 ? -7.710 30.948 18.750 1.00 12.23 ? 6 PRO A CA 1 6 UNP O57413 195 P
ATOM 34 C C . PRO A 1 6 ? -6.513 30.420 19.566 1.00 12.04 ? 6 PRO A C 1 6 UNP O57413 195 P
ATOM 35 O O . PRO A 1 6 ? -5.823 29.484 19.137 1.00 12.46 ? 6 PRO A O 1 6 UNP O57413 195 P
ATOM 36 C CB . PRO A 1 6 ? -9.004 30.213 19.063 1.00 12.40 ? 6 PRO A CB 1 6 UNP O57413 195 P
ATOM 37 C CG . PRO A 1 6 ? -8.872 28.979 18.228 1.00 12.36 ? 6 PRO A CG 1 6 UNP O57413 195 P
ATOM 38 C CD . PRO A 1 6 ? -8.359 29.516 16.911 1.00 12.08 ? 6 PRO A CD 1 6 UNP O57413 195 P
ATOM 39 N N . GLN A 1 7 ? -6.256 31.015 20.719 1.00 10.79 ? 7 GLN A N 1 7 UNP O57413 196 Q
ATOM 40 C CA . GLN A 1 7 ? -5.119 30.628 21.558 1.00 9.76 ? 7 GLN A CA 1 7 UNP O57413 196 Q
ATOM 41 C C . GLN A 1 7 ? -5.206 29.196 22.050 1.00 9.22 ? 7 GLN A C 1 7 UNP O57413 196 Q
ATOM 42 O O . GLN A 1 7 ? -6.264 28.739 22.509 1.00 9.60 ? 7 GLN A O 1 7 UNP O57413 196 Q
ATOM 43 C CB . GLN A 1 7 ? -5.066 31.531 22.799 1.00 10.05 ? 7 GLN A CB 1 7 UNP O57413 196 Q
ATOM 44 C CG . GLN A 1 7 ? -3.868 31.249 23.702 1.00 12.43 ? 7 GLN A CG 1 7 UNP O57413 196 Q
ATOM 45 C CD . GLN A 1 7 ? -2.577 31.763 23.093 1.00 13.15 ? 7 GLN A CD 1 7 UNP O57413 196 Q
ATOM 46 O OE1 . GLN A 1 7 ? -2.428 32.952 22.843 1.00 14.73 ? 7 GLN A OE1 1 7 UNP O57413 196 Q
ATOM 47 N NE2 . GLN A 1 7 ? -1.638 30.863 22.832 1.00 13.01 ? 7 GLN A NE2 1 7 UNP O57413 196 Q
ATOM 48 N N . ARG A 1 8 ? -4.088 28.478 21.908 1.00 7.83 ? 8 ARG A N 1 8 UNP O57413 197 R
ATOM 49 C CA . ARG A 1 8 ? -3.996 27.130 22.471 1.00 7.80 ? 8 ARG A CA 1 8 UNP O57413 197 R
ATOM 50 C C . ARG A 1 8 ? -2.637 27.041 23.157 1.00 7.16 ? 8 ARG A C 1 8 UNP O57413 197 R
ATOM 51 O O . ARG A 1 8 ? -1.764 27.911 23.001 1.00 7.39 ? 8 ARG A O 1 8 UNP O57413 197 R
ATOM 52 C CB . ARG A 1 8 ? -4.157 26.034 21.409 1.00 9.11 ? 8 ARG A CB 1 8 UNP O57413 197 R
ATOM 53 C CG . ARG A 1 8 ? -5.551 25.972 20.816 1.00 9.07 ? 8 ARG A CG 1 8 UNP O57413 197 R
ATOM 54 C CD . ARG A 1 8 ? -6.525 25.406 21.827 1.00 9.62 ? 8 ARG A CD 1 8 UNP O57413 197 R
ATOM 55 N NE . ARG A 1 8 ? -7.856 25.106 21.274 1.00 10.97 ? 8 ARG A NE 1 8 UNP O57413 197 R
ATOM 56 C CZ . ARG A 1 8 ? -8.820 25.998 21.071 1.00 11.70 ? 8 ARG A CZ 1 8 UNP O57413 197 R
ATOM 57 N NH1 . ARG A 1 8 ? -9.983 25.584 20.585 1.00 13.09 ? 8 ARG A NH1 1 8 UNP O57413 197 R
ATOM 58 N NH2 . ARG A 1 8 ? -8.628 27.280 21.350 1.00 13.45 ? 8 ARG A NH2 1 8 UNP O57413 197 R
ATOM 59 N N . TYR A 1 9 ? -2.455 25.961 23.882 1.00 7.65 ? 9 TYR A N 1 9 UNP O57413 198 Y
ATOM 60 C CA . TYR A 1 9 ? -1.238 25.738 24.640 1.00 7.86 ? 9 TYR A CA 1 9 UNP O57413 198 Y
ATOM 61 C C . TYR A 1 9 ? -0.834 24.279 24.569 1.00 9.14 ? 9 TYR A C 1 9 UNP O57413 198 Y
ATOM 62 O O . TYR A 1 9 ? -1.686 23.409 24.701 1.00 11.80 ? 9 TYR A O 1 9 UNP O57413 198 Y
ATOM 63 C CB . TYR A 1 9 ? -1.445 26.062 26.117 1.00 9.89 ? 9 TYR A CB 1 9 UNP O57413 198 Y
ATOM 64 C CG . TYR A 1 9 ? -2.058 27.407 26.375 1.00 9.51 ? 9 TYR A CG 1 9 UNP O57413 198 Y
ATOM 65 C CD1 . TYR A 1 9 ? -3.438 27.573 26.337 1.00 11.11 ? 9 TYR A CD1 1 9 UNP O57413 198 Y
ATOM 66 C CD2 . TYR A 1 9 ? -1.258 28.512 26.646 1.00 10.66 ? 9 TYR A CD2 1 9 UNP O57413 198 Y
ATOM 67 C CE1 . TYR A 1 9 ? -4.015 28.823 26.569 1.00 11.29 ? 9 TYR A CE1 1 9 UNP O57413 198 Y
ATOM 68 C CE2 . TYR A 1 9 ? -1.830 29.768 26.881 1.00 11.15 ? 9 TYR A CE2 1 9 UNP O57413 198 Y
ATOM 69 C CZ . TYR A 1 9 ? -3.200 29.897 26.841 1.00 12.11 ? 9 TYR A CZ 1 9 UNP O57413 198 Y
ATOM 70 O OH . TYR A 1 9 ? -3.762 31.115 27.135 1.00 14.84 ? 9 TYR A OH 1 9 UNP O57413 198 Y
ATOM 71 N N . ILE A 1 10 ? 0.442 24.002 24.367 1.00 8.13 ? 10 ILE A N 1 10 UNP O57413 199 I
ATOM 72 C CA . ILE A 1 10 ? 0.880 22.606 24.426 1.00 7.96 ? 10 ILE A CA 1 10 UNP O57413 199 I
ATOM 73 C C . ILE A 1 10 ? 2.018 22.524 25.430 1.00 7.54 ? 10 ILE A C 1 10 UNP O57413 199 I
ATOM 74 O O . ILE A 1 10 ? 3.069 23.147 25.255 1.00 7.64 ? 10 ILE A O 1 10 UNP O57413 199 I
ATOM 75 C CB . ILE A 1 10 ? 1.350 22.040 23.061 1.00 7.74 ? 10 ILE A CB 1 10 UNP O57413 199 I
ATOM 76 C CG1 . ILE A 1 10 ? 0.160 21.963 22.083 1.00 9.61 ? 10 ILE A CG1 1 10 UNP O57413 199 I
ATOM 77 C CG2 . ILE A 1 10 ? 1.979 20.654 23.265 1.00 8.57 ? 10 ILE A CG2 1 10 UNP O57413 199 I
ATOM 78 C CD1 . ILE A 1 10 ? 0.531 21.602 20.657 1.00 9.54 ? 10 ILE A CD1 1 10 UNP O57413 199 I
ATOM 79 N N . GLU A 1 11 ? 1.769 21.786 26.503 1.00 7.35 ? 11 GLU A N 1 11 UNP O57413 200 K
ATOM 80 C CA . GLU A 1 11 ? 2.755 21.565 27.557 1.00 8.07 ? 11 GLU A CA 1 11 UNP O57413 200 K
ATOM 81 C C . GLU A 1 11 ? 3.493 20.286 27.217 1.00 7.11 ? 11 GLU A C 1 11 UNP O57413 200 K
ATOM 82 O O . GLU A 1 11 ? 2.939 19.182 27.312 1.00 7.70 ? 11 GLU A O 1 11 UNP O57413 200 K
ATOM 83 C CB . GLU A 1 11 ? 2.076 21.440 28.905 1.00 12.08 ? 11 GLU A CB 1 11 UNP O57413 200 K
ATOM 84 C CG . GLU A 1 11 ? 1.719 22.777 29.461 1.00 18.78 ? 11 GLU A CG 1 11 UNP O57413 200 K
ATOM 85 C CD . GLU A 1 11 ? 0.307 23.137 29.204 1.00 21.67 ? 11 GLU A CD 1 11 UNP O57413 200 K
ATOM 86 O OE1 . GLU A 1 11 ? 0.019 23.770 28.160 1.00 25.55 ? 11 GLU A OE1 1 11 UNP O57413 200 K
ATOM 87 O OE2 . GLU A 1 11 ? -0.524 22.773 30.062 1.00 23.76 ? 11 GLU A OE2 1 11 UNP O57413 200 K
ATOM 88 N N . LEU A 1 12 ? 4.742 20.436 26.810 1.00 6.19 ? 12 LEU A N 1 12 UNP O57413 201 L
ATOM 89 C CA . LEU A 1 12 ? 5.529 19.308 26.347 1.00 5.84 ? 12 LEU A CA 1 12 UNP O57413 201 L
ATOM 90 C C . LEU A 1 12 ? 6.369 18.616 27.355 1.00 5.91 ? 12 LEU A C 1 12 UNP O57413 201 L
ATOM 91 O O . LEU A 1 12 ? 6.912 19.246 28.266 1.00 8.08 ? 12 LEU A O 1 12 UNP O57413 201 L
ATOM 92 C CB . LEU A 1 12 ? 6.529 19.771 25.283 1.00 8.01 ? 12 LEU A CB 1 12 UNP O57413 201 L
ATOM 93 C CG . LEU A 1 12 ? 6.132 20.270 23.928 1.00 9.53 ? 12 LEU A CG 1 12 UNP O57413 201 L
ATOM 94 C CD1 . LEU A 1 12 ? 7.406 20.679 23.202 1.00 9.92 ? 12 LEU A CD1 1 12 UNP O57413 201 L
ATOM 95 C CD2 . LEU A 1 12 ? 5.467 19.151 23.162 1.00 10.11 ? 12 LEU A CD2 1 12 UNP O57413 201 L
ATOM 96 N N . ALA A 1 13 ? 6.450 17.301 27.250 1.00 5.43 ? 13 ALA A N 1 13 UNP O57413 202 A
ATOM 97 C CA . ALA A 1 13 ? 7.453 16.558 28.000 1.00 5.13 ? 13 ALA A CA 1 13 UNP O57413 202 A
ATOM 98 C C . ALA A 1 13 ? 8.439 16.036 26.945 1.00 5.10 ? 13 ALA A C 1 13 UNP O57413 202 A
ATOM 99 O O . ALA A 1 13 ? 8.042 15.582 25.855 1.00 6.52 ? 13 ALA A O 1 13 UNP O57413 202 A
ATOM 100 C CB . ALA A 1 13 ? 6.858 15.390 28.762 1.00 6.77 ? 13 ALA A CB 1 13 UNP O57413 202 A
ATOM 101 N N . ILE A 1 14 ? 9.721 16.163 27.234 1.00 5.38 ? 14 ILE A N 1 14 UNP O57413 203 I
ATOM 102 C CA . ILE A 1 14 ? 10.762 15.630 26.350 1.00 6.35 ? 14 ILE A CA 1 14 UNP O57413 203 I
ATOM 103 C C . ILE A 1 14 ? 11.536 14.627 27.172 1.00 6.70 ? 14 ILE A C 1 14 UNP O57413 203 I
ATOM 104 O O . ILE A 1 14 ? 11.952 14.918 28.306 1.00 6.57 ? 14 ILE A O 1 14 UNP O57413 203 I
ATOM 105 C CB . ILE A 1 14 ? 11.741 16.742 25.859 1.00 7.15 ? 14 ILE A CB 1 14 UNP O57413 203 I
ATOM 106 C CG1 . ILE A 1 14 ? 11.005 17.801 25.012 1.00 7.95 ? 14 ILE A CG1 1 14 UNP O57413 203 I
ATOM 107 C CG2 . ILE A 1 14 ? 12.883 16.075 25.093 1.00 8.23 ? 14 ILE A CG2 1 14 UNP O57413 203 I
ATOM 108 C CD1 . ILE A 1 14 ? 10.254 17.264 23.803 1.00 10.84 ? 14 ILE A CD1 1 14 UNP O57413 203 I
ATOM 109 N N . VAL A 1 15 ? 11.715 13.435 26.615 1.00 6.18 ? 15 VAL A N 1 15 UNP O57413 204 V
ATOM 110 C CA . VAL A 1 15 ? 12.463 12.366 27.268 1.00 6.42 ? 15 VAL A CA 1 15 UNP O57413 204 V
ATOM 111 C C . VAL A 1 15 ? 13.704 12.098 26.439 1.00 5.89 ? 15 VAL A C 1 15 UNP O57413 204 V
ATOM 112 O O . VAL A 1 15 ? 13.579 11.918 25.215 1.00 7.24 ? 15 VAL A O 1 15 UNP O57413 204 V
ATOM 113 C CB . VAL A 1 15 ? 11.581 11.095 27.367 1.00 7.20 ? 15 VAL A CB 1 15 UNP O57413 204 V
ATOM 114 C CG1 . VAL A 1 15 ? 12.372 9.975 28.039 1.00 8.71 ? 15 VAL A CG1 1 15 UNP O57413 204 V
ATOM 115 C CG2 . VAL A 1 15 ? 10.265 11.427 28.086 1.00 8.72 ? 15 VAL A CG2 1 15 UNP O57413 204 V
ATOM 116 N N . VAL A 1 16 ? 14.880 12.094 27.066 1.00 6.23 ? 16 VAL A N 1 16 UNP O57413 205 V
ATOM 117 C CA . VAL A 1 16 ? 16.140 11.873 26.344 1.00 6.58 ? 16 VAL A CA 1 16 UNP O57413 205 V
ATOM 118 C C . VAL A 1 16 ? 16.581 10.490 26.756 1.00 6.07 ? 16 VAL A C 1 16 UNP O57413 205 V
ATOM 119 O O . VAL A 1 16 ? 16.759 10.229 27.949 1.00 7.46 ? 16 VAL A O 1 16 UNP O57413 205 V
ATOM 120 C CB . VAL A 1 16 ? 17.183 12.945 26.732 1.00 5.81 ? 16 VAL A CB 1 16 UNP O57413 205 V
ATOM 121 C CG1 . VAL A 1 16 ? 18.557 12.617 26.108 1.00 8.41 ? 16 VAL A CG1 1 16 UNP O57413 205 V
ATOM 122 C CG2 . VAL A 1 16 ? 16.700 14.322 26.268 1.00 8.05 ? 16 VAL A CG2 1 16 UNP O57413 205 V
ATOM 123 N N . ASP A 1 17 ? 16.740 9.596 25.790 1.00 6.26 ? 17 ASP A N 1 17 UNP O57413 206 D
ATOM 124 C CA . ASP A 1 17 ? 17.083 8.227 26.160 1.00 7.84 ? 17 ASP A CA 1 17 UNP O57413 206 D
ATOM 125 C C . ASP A 1 17 ? 18.548 8.048 26.532 1.00 7.43 ? 17 ASP A C 1 17 UNP O57413 206 D
ATOM 126 O O . ASP A 1 17 ? 19.346 8.968 26.432 1.00 7.55 ? 17 ASP A O 1 17 UNP O57413 206 D
ATOM 127 C CB . ASP A 1 17 ? 16.585 7.258 25.068 1.00 7.39 ? 17 ASP A CB 1 17 UNP O57413 206 D
ATOM 128 C CG . ASP A 1 17 ? 17.502 7.149 23.867 1.00 6.85 ? 17 ASP A CG 1 17 UNP O57413 206 D
ATOM 129 O OD1 . ASP A 1 17 ? 17.205 6.254 23.079 1.00 8.57 ? 17 ASP A OD1 1 17 UNP O57413 206 D
ATOM 130 O OD2 . ASP A 1 17 ? 18.448 7.915 23.704 1.00 8.41 ? 17 ASP A OD2 1 17 UNP O57413 206 D
ATOM 131 N N . HIS A 1 18 ? 18.898 6.846 26.994 1.00 8.39 ? 18 HIS A N 1 18 UNP O57413 207 H
ATOM 132 C CA . HIS A 1 18 ? 20.248 6.615 27.446 1.00 9.17 ? 18 HIS A CA 1 18 UNP O57413 207 H
ATOM 133 C C . HIS A 1 18 ? 21.311 6.718 26.362 1.00 8.82 ? 18 HIS A C 1 18 UNP O57413 207 H
ATOM 134 O O . HIS A 1 18 ? 22.407 7.199 26.636 1.00 10.13 ? 18 HIS A O 1 18 UNP O57413 207 H
ATOM 135 C CB . HIS A 1 18 ? 20.322 5.271 28.174 1.00 11.22 ? 18 HIS A CB 1 18 UNP O57413 207 H
ATOM 136 C CG . HIS A 1 18 ? 21.581 5.104 28.968 1.00 14.01 ? 18 HIS A CG 1 18 UNP O57413 207 H
ATOM 137 N ND1 . HIS A 1 18 ? 21.856 5.869 30.084 1.00 15.48 ? 18 HIS A ND1 1 18 UNP O57413 207 H
ATOM 138 C CD2 . HIS A 1 18 ? 22.665 4.314 28.774 1.00 15.64 ? 18 HIS A CD2 1 18 UNP O57413 207 H
ATOM 139 C CE1 . HIS A 1 18 ? 23.060 5.559 30.537 1.00 16.68 ? 18 HIS A CE1 1 18 UNP O57413 207 H
ATOM 140 N NE2 . HIS A 1 18 ? 23.572 4.621 29.761 1.00 15.90 ? 18 HIS A NE2 1 18 UNP O57413 207 H
ATOM 141 N N . GLY A 1 19 ? 20.971 6.345 25.133 1.00 8.87 ? 19 GLY A N 1 19 UNP O57413 208 G
ATOM 142 C CA . GLY A 1 19 ? 21.953 6.444 24.061 1.00 9.49 ? 19 GLY A CA 1 19 UNP O57413 208 G
ATOM 143 C C . GLY A 1 19 ? 22.249 7.913 23.769 1.00 9.70 ? 19 GLY A C 1 19 UNP O57413 208 G
ATOM 144 O O . GLY A 1 19 ? 23.393 8.298 23.515 1.00 9.80 ? 19 GLY A O 1 19 UNP O57413 208 G
ATOM 145 N N . MET A 1 20 ? 21.225 8.758 23.823 1.00 9.74 ? 20 MET A N 1 20 UNP O57413 209 M
ATOM 146 C CA . MET A 1 20 ? 21.493 10.172 23.549 1.00 10.42 ? 20 MET A CA 1 20 UNP O57413 209 M
ATOM 147 C C . MET A 1 20 ? 22.288 10.764 24.728 1.00 10.42 ? 20 MET A C 1 20 UNP O57413 209 M
ATOM 148 O O . MET A 1 20 ? 23.171 11.587 24.526 1.00 10.16 ? 20 MET A O 1 20 UNP O57413 209 M
ATOM 149 C CB . MET A 1 20 ? 20.177 10.931 23.266 1.00 11.57 ? 20 MET A CB 1 20 UNP O57413 209 M
ATOM 150 C CG . MET A 1 20 ? 20.391 12.425 22.976 1.00 13.31 ? 20 MET A CG 1 20 UNP O57413 209 M
ATOM 151 S SD . MET A 1 20 ? 18.892 13.158 22.256 1.00 14.59 ? 20 MET A SD 1 20 UNP O57413 209 M
ATOM 152 C CE . MET A 1 20 ? 19.379 14.944 22.212 1.00 16.85 ? 20 MET A CE 1 20 UNP O57413 209 M
ATOM 153 N N . TYR A 1 21 ? 21.986 10.324 25.949 1.00 10.90 ? 21 TYR A N 1 21 UNP O57413 210 Y
ATOM 154 C CA . TYR A 1 21 ? 22.714 10.797 27.127 1.00 11.75 ? 21 TYR A CA 1 21 UNP O57413 210 Y
ATOM 155 C C . TYR A 1 21 ? 24.218 10.513 26.928 1.00 12.15 ? 21 TYR A C 1 21 UNP O57413 210 Y
ATOM 156 O O . TYR A 1 21 ? 25.040 11.395 27.129 1.00 13.46 ? 21 TYR A O 1 21 UNP O57413 210 Y
ATOM 157 C CB . TYR A 1 21 ? 22.202 10.072 28.379 1.00 12.72 ? 21 TYR A CB 1 21 UNP O57413 210 Y
ATOM 158 C CG . TYR A 1 21 ? 22.950 10.386 29.663 1.00 14.98 ? 21 TYR A CG 1 21 UNP O57413 210 Y
ATOM 159 C CD1 . TYR A 1 21 ? 22.828 11.620 30.259 1.00 15.91 ? 21 TYR A CD1 1 21 UNP O57413 210 Y
ATOM 160 C CD2 . TYR A 1 21 ? 23.748 9.424 30.281 1.00 16.93 ? 21 TYR A CD2 1 21 UNP O57413 210 Y
ATOM 161 C CE1 . TYR A 1 21 ? 23.465 11.905 31.446 1.00 17.25 ? 21 TYR A CE1 1 21 UNP O57413 210 Y
ATOM 162 C CE2 . TYR A 1 21 ? 24.392 9.696 31.472 1.00 17.14 ? 21 TYR A CE2 1 21 UNP O57413 210 Y
ATOM 163 C CZ . TYR A 1 21 ? 24.240 10.938 32.053 1.00 18.27 ? 21 TYR A CZ 1 21 UNP O57413 210 Y
ATOM 164 O OH . TYR A 1 21 ? 24.796 11.226 33.294 1.00 20.93 ? 21 TYR A OH 1 21 UNP O57413 210 Y
ATOM 165 N N . THR A 1 22 ? 24.543 9.297 26.499 1.00 12.03 ? 22 THR A N 1 22 UNP O57413 211 T
ATOM 166 C CA . THR A 1 22 ? 25.927 8.868 26.274 1.00 13.31 ? 22 THR A CA 1 22 UNP O57413 211 T
ATOM 167 C C . THR A 1 22 ? 26.565 9.638 25.118 1.00 12.55 ? 22 THR A C 1 22 UNP O57413 211 T
ATOM 168 O O . THR A 1 22 ? 27.748 10.015 25.170 1.00 12.33 ? 22 THR A O 1 22 UNP O57413 211 T
ATOM 169 C CB . THR A 1 22 ? 25.962 7.349 25.996 1.00 14.07 ? 22 THR A CB 1 22 UNP O57413 211 T
ATOM 170 O OG1 . THR A 1 22 ? 25.383 6.673 27.122 1.00 16.66 ? 22 THR A OG1 1 22 UNP O57413 211 T
ATOM 171 C CG2 . THR A 1 22 ? 27.411 6.860 25.797 1.00 15.97 ? 22 THR A CG2 1 22 UNP O57413 211 T
ATOM 172 N N . LYS A 1 23 ? 25.787 9.887 24.070 1.00 12.03 ? 23 LYS A N 1 23 UNP O57413 212 K
ATOM 173 C CA . LYS A 1 23 ? 26.262 10.633 22.902 1.00 12.21 ? 23 LYS A CA 1 23 UNP O57413 212 K
ATOM 174 C C . LYS A 1 23 ? 26.744 12.034 23.304 1.00 12.44 ? 23 LYS A C 1 23 UNP O57413 212 K
ATOM 175 O O . LYS A 1 23 ? 27.723 12.545 22.757 1.00 12.72 ? 23 LYS A O 1 23 UNP O57413 212 K
ATOM 176 C CB . LYS A 1 23 ? 25.124 10.762 21.868 1.00 11.07 ? 23 LYS A CB 1 23 UNP O57413 212 K
ATOM 177 C CG . LYS A 1 23 ? 25.391 11.713 20.703 1.00 10.06 ? 23 LYS A CG 1 23 UNP O57413 212 K
ATOM 178 C CD . LYS A 1 23 ? 24.239 11.634 19.674 1.00 10.53 ? 23 LYS A CD 1 23 UNP O57413 212 K
ATOM 179 C CE . LYS A 1 23 ? 24.442 12.622 18.554 1.00 10.60 ? 23 LYS A CE 1 23 UNP O57413 212 K
ATOM 180 N NZ . LYS A 1 23 ? 23.232 12.643 17.632 1.00 11.21 ? 23 LYS A NZ 1 23 UNP O57413 212 K
ATOM 181 N N . TYR A 1 24 ? 26.037 12.652 24.247 1.00 12.64 ? 24 TYR A N 1 24 UNP O57413 213 Y
ATOM 182 C CA . TYR A 1 24 ? 26.394 13.998 24.686 1.00 13.80 ? 24 TYR A CA 1 24 UNP O57413 213 Y
ATOM 183 C C . TYR A 1 24 ? 27.256 13.983 25.931 1.00 15.01 ? 24 TYR A C 1 24 UNP O57413 213 Y
ATOM 184 O O . TYR A 1 24 ? 27.081 14.794 26.856 1.00 15.35 ? 24 TYR A O 1 24 UNP O57413 213 Y
ATOM 185 C CB . TYR A 1 24 ? 25.115 14.832 24.893 1.00 14.08 ? 24 TYR A CB 1 24 UNP O57413 213 Y
ATOM 186 C CG . TYR A 1 24 ? 24.520 15.239 23.562 1.00 13.19 ? 24 TYR A CG 1 24 UNP O57413 213 Y
ATOM 187 C CD1 . TYR A 1 24 ? 25.036 16.321 22.849 1.00 14.58 ? 24 TYR A CD1 1 24 UNP O57413 213 Y
ATOM 188 C CD2 . TYR A 1 24 ? 23.549 14.445 22.937 1.00 12.88 ? 24 TYR A CD2 1 24 UNP O57413 213 Y
ATOM 189 C CE1 . TYR A 1 24 ? 24.617 16.596 21.548 1.00 15.15 ? 24 TYR A CE1 1 24 UNP O57413 213 Y
ATOM 190 C CE2 . TYR A 1 24 ? 23.121 14.721 21.633 1.00 12.08 ? 24 TYR A CE2 1 24 UNP O57413 213 Y
ATOM 191 C CZ . TYR A 1 24 ? 23.656 15.789 20.952 1.00 13.34 ? 24 TYR A CZ 1 24 UNP O57413 213 Y
ATOM 192 O OH . TYR A 1 24 ? 23.251 16.097 19.669 1.00 15.06 ? 24 TYR A OH 1 24 UNP O57413 213 Y
ATOM 193 N N . SER A 1 25 ? 28.180 13.024 25.968 1.00 15.29 ? 25 SER A N 1 25 UNP O57413 214 S
ATOM 194 C CA . SER A 1 25 ? 29.118 12.895 27.093 1.00 16.67 ? 25 SER A CA 1 25 UNP O57413 214 S
ATOM 195 C C . SER A 1 25 ? 28.532 12.778 28.492 1.00 16.08 ? 25 SER A C 1 25 UNP O57413 214 S
ATOM 196 O O . SER A 1 25 ? 29.154 13.239 29.464 1.00 16.33 ? 25 SER A O 1 25 UNP O57413 214 S
ATOM 197 C CB . SER A 1 25 ? 30.059 14.075 27.078 1.00 17.95 ? 25 SER A CB 1 25 UNP O57413 214 S
ATOM 198 O OG . SER A 1 25 ? 30.621 14.199 25.798 1.00 20.66 ? 25 SER A OG 1 25 UNP O57413 214 S
ATOM 199 N N . SER A 1 26 ? 27.348 12.185 28.607 1.00 15.33 ? 26 SER A N 1 26 UNP O57413 215 S
ATOM 200 C CA . SER A 1 26 ? 26.703 12.019 29.900 1.00 15.51 ? 26 SER A CA 1 26 UNP O57413 215 S
ATOM 201 C C . SER A 1 26 ? 26.654 13.346 30.640 1.00 15.95 ? 26 SER A C 1 26 UNP O57413 215 S
ATOM 202 O O . SER A 1 26 ? 26.721 13.360 31.863 1.00 17.00 ? 26 SER A O 1 26 UNP O57413 215 S
ATOM 203 C CB . SER A 1 26 ? 27.490 10.990 30.726 1.00 15.77 ? 26 SER A CB 1 26 UNP O57413 215 S
ATOM 204 O OG . SER A 1 26 ? 27.590 9.785 29.983 1.00 17.28 ? 26 SER A OG 1 26 UNP O57413 215 S
ATOM 205 N N . ASN A 1 27 ? 26.491 14.445 29.899 1.00 15.33 ? 27 ASN A N 1 27 UNP O57413 216 N
ATOM 206 C CA . ASN A 1 27 ? 26.488 15.799 30.470 1.00 15.88 ? 27 ASN A CA 1 27 UNP O57413 216 N
ATOM 207 C C . ASN A 1 27 ? 25.062 16.362 30.506 1.00 15.39 ? 27 ASN A C 1 27 UNP O57413 216 N
ATOM 208 O O . ASN A 1 27 ? 24.557 16.843 29.495 1.00 14.63 ? 27 ASN A O 1 27 UNP O57413 216 N
ATOM 209 C CB . ASN A 1 27 ? 27.435 16.662 29.607 1.00 16.61 ? 27 ASN A CB 1 27 UNP O57413 216 N
ATOM 210 C CG . ASN A 1 27 ? 27.610 18.095 30.105 1.00 18.69 ? 27 ASN A CG 1 27 UNP O57413 216 N
ATOM 211 O OD1 . ASN A 1 27 ? 28.607 18.756 29.763 1.00 22.08 ? 27 ASN A OD1 1 27 UNP O57413 216 N
ATOM 212 N ND2 . ASN A 1 27 ? 26.665 18.590 30.868 1.00 16.67 ? 27 ASN A ND2 1 27 UNP O57413 216 N
ATOM 213 N N . PHE A 1 28 ? 24.420 16.292 31.665 1.00 15.54 ? 28 PHE A N 1 28 UNP O57413 217 F
ATOM 214 C CA . PHE A 1 28 ? 23.052 16.795 31.810 1.00 15.58 ? 28 PHE A CA 1 28 UNP O57413 217 F
ATOM 215 C C . PHE A 1 28 ? 22.876 18.255 31.386 1.00 16.05 ? 28 PHE A C 1 28 UNP O57413 217 F
ATOM 216 O O . PHE A 1 28 ? 21.932 18.581 30.668 1.00 15.68 ? 28 PHE A O 1 28 UNP O57413 217 F
ATOM 217 C CB . PHE A 1 28 ? 22.564 16.623 33.254 1.00 17.15 ? 28 PHE A CB 1 28 UNP O57413 217 F
ATOM 218 C CG . PHE A 1 28 ? 21.181 17.164 33.487 1.00 17.79 ? 28 PHE A CG 1 28 UNP O57413 217 F
ATOM 219 C CD1 . PHE A 1 28 ? 20.043 16.402 33.182 1.00 18.01 ? 28 PHE A CD1 1 28 UNP O57413 217 F
ATOM 220 C CD2 . PHE A 1 28 ? 21.014 18.470 33.940 1.00 17.89 ? 28 PHE A CD2 1 28 UNP O57413 217 F
ATOM 221 C CE1 . PHE A 1 28 ? 18.743 16.957 33.325 1.00 18.27 ? 28 PHE A CE1 1 28 UNP O57413 217 F
ATOM 222 C CE2 . PHE A 1 28 ? 19.742 19.029 34.084 1.00 18.51 ? 28 PHE A CE2 1 28 UNP O57413 217 F
ATOM 223 C CZ . PHE A 1 28 ? 18.604 18.274 33.775 1.00 18.01 ? 28 PHE A CZ 1 28 UNP O57413 217 F
ATOM 224 N N . LYS A 1 29 ? 23.762 19.138 31.834 1.00 15.97 ? 29 LYS A N 1 29 UNP O57413 218 K
ATOM 225 C CA . LYS A 1 29 ? 23.673 20.560 31.491 1.00 16.81 ? 29 LYS A CA 1 29 UNP O57413 218 K
ATOM 226 C C . LYS A 1 29 ? 23.667 20.772 29.996 1.00 15.38 ? 29 LYS A C 1 29 UNP O57413 218 K
ATOM 227 O O . LYS A 1 29 ? 22.856 21.538 29.487 1.00 13.90 ? 29 LYS A O 1 29 UNP O57413 218 K
ATOM 228 C CB . LYS A 1 29 ? 24.849 21.333 32.093 1.00 18.81 ? 29 LYS A CB 1 29 UNP O57413 218 K
ATOM 229 C CG . LYS A 1 29 ? 24.951 21.199 33.585 1.00 22.39 ? 29 LYS A CG 1 29 UNP O57413 218 K
ATOM 230 C CD . LYS A 1 29 ? 23.735 21.733 34.297 1.00 25.38 ? 29 LYS A CD 1 29 UNP O57413 218 K
ATOM 231 C CE . LYS A 1 29 ? 23.833 21.453 35.802 1.00 26.98 ? 29 LYS A CE 1 29 UNP O57413 218 K
ATOM 232 N NZ . LYS A 1 29 ? 22.646 21.965 36.541 1.00 29.48 ? 29 LYS A NZ 1 29 UNP O57413 218 K
ATOM 233 N N . LYS A 1 30 ? 24.571 20.094 29.290 1.00 14.47 ? 30 LYS A N 1 30 UNP O57413 219 K
ATOM 234 C CA . LYS A 1 30 ? 24.644 20.233 27.841 1.00 13.99 ? 30 LYS A CA 1 30 UNP O57413 219 K
ATOM 235 C C . LYS A 1 30 ? 23.374 19.709 27.167 1.00 11.98 ? 30 LYS A C 1 30 UNP O57413 219 K
ATOM 236 O O . LYS A 1 30 ? 22.896 20.319 26.227 1.00 12.53 ? 30 LYS A O 1 30 UNP O57413 219 K
ATOM 237 C CB . LYS A 1 30 ? 25.861 19.499 27.276 1.00 16.89 ? 30 LYS A CB 1 30 UNP O57413 219 K
ATOM 238 C CG . LYS A 1 30 ? 26.004 19.704 25.780 1.00 19.72 ? 30 LYS A CG 1 30 UNP O57413 219 K
ATOM 239 C CD . LYS A 1 30 ? 27.045 18.792 25.151 1.00 23.78 ? 30 LYS A CD 1 30 UNP O57413 219 K
ATOM 240 C CE . LYS A 1 30 ? 28.432 19.056 25.685 1.00 24.99 ? 30 LYS A CE 1 30 UNP O57413 219 K
ATOM 241 N NZ . LYS A 1 30 ? 29.422 18.174 24.970 1.00 26.89 ? 30 LYS A NZ 1 30 UNP O57413 219 K
ATOM 242 N N . ILE A 1 31 ? 22.849 18.594 27.654 1.00 10.45 ? 31 ILE A N 1 31 UNP O57413 220 I
ATOM 243 C CA . ILE A 1 31 ? 21.621 17.994 27.105 1.00 9.61 ? 31 ILE A CA 1 31 UNP O57413 220 I
ATOM 244 C C . ILE A 1 31 ? 20.442 18.942 27.364 1.00 9.33 ? 31 ILE A C 1 31 UNP O57413 220 I
ATOM 245 O O . ILE A 1 31 ? 19.628 19.205 26.481 1.00 8.30 ? 31 ILE A O 1 31 UNP O57413 220 I
ATOM 246 C CB . ILE A 1 31 ? 21.353 16.642 27.770 1.00 10.39 ? 31 ILE A CB 1 31 UNP O57413 220 I
ATOM 247 C CG1 . ILE A 1 31 ? 22.450 15.657 27.330 1.00 11.29 ? 31 ILE A CG1 1 31 UNP O57413 220 I
ATOM 248 C CG2 . ILE A 1 31 ? 19.972 16.133 27.414 1.00 10.78 ? 31 ILE A CG2 1 31 UNP O57413 220 I
ATOM 249 C CD1 . ILE A 1 31 ? 22.443 14.385 28.068 1.00 13.12 ? 31 ILE A CD1 1 31 UNP O57413 220 I
ATOM 250 N N . ARG A 1 32 ? 20.352 19.486 28.568 1.00 9.28 ? 32 ARG A N 1 32 UNP O57413 221 R
ATOM 251 C CA . ARG A 1 32 ? 19.254 20.417 28.879 1.00 9.87 ? 32 ARG A CA 1 32 UNP O57413 221 R
ATOM 252 C C . ARG A 1 32 ? 19.312 21.641 27.959 1.00 9.33 ? 32 ARG A C 1 32 UNP O57413 221 R
ATOM 253 O O . ARG A 1 32 ? 18.283 22.119 27.449 1.00 8.48 ? 32 ARG A O 1 32 UNP O57413 221 R
ATOM 254 C CB . ARG A 1 32 ? 19.347 20.893 30.334 1.00 11.24 ? 32 ARG A CB 1 32 UNP O57413 221 R
ATOM 255 C CG . ARG A 1 32 ? 18.152 21.785 30.742 1.00 12.70 ? 32 ARG A CG 1 32 UNP O57413 221 R
ATOM 256 C CD . ARG A 1 32 ? 18.199 22.118 32.241 1.00 17.68 ? 32 ARG A CD 1 32 UNP O57413 221 R
ATOM 257 N NE . ARG A 1 32 ? 19.377 22.888 32.571 1.00 21.26 ? 32 ARG A NE 1 32 UNP O57413 221 R
ATOM 258 C CZ . ARG A 1 32 ? 19.766 23.150 33.815 1.00 23.99 ? 32 ARG A CZ 1 32 UNP O57413 221 R
ATOM 259 N NH1 . ARG A 1 32 ? 19.050 22.688 34.840 1.00 25.49 ? 32 ARG A NH1 1 32 UNP O57413 221 R
ATOM 260 N NH2 . ARG A 1 32 ? 20.861 23.880 34.030 1.00 24.84 ? 32 ARG A NH2 1 32 UNP O57413 221 R
ATOM 261 N N . LYS A 1 33 ? 20.497 22.181 27.746 1.00 8.94 ? 33 LYS A N 1 33 UNP O57413 222 K
ATOM 262 C CA . LYS A 1 33 ? 20.617 23.337 26.873 1.00 10.22 ? 33 LYS A CA 1 33 UNP O57413 222 K
ATOM 263 C C . LYS A 1 33 ? 20.125 22.990 25.462 1.00 9.08 ? 33 LYS A C 1 33 UNP O57413 222 K
ATOM 264 O O . LYS A 1 33 ? 19.399 23.759 24.851 1.00 9.61 ? 33 LYS A O 1 33 UNP O57413 222 K
ATOM 265 C CB . LYS A 1 33 ? 22.078 23.818 26.790 1.00 11.94 ? 33 LYS A CB 1 33 UNP O57413 222 K
ATOM 266 C CG . LYS A 1 33 ? 22.272 25.041 25.922 1.00 17.49 ? 33 LYS A CG 1 33 UNP O57413 222 K
ATOM 267 C CD . LYS A 1 33 ? 23.743 25.384 25.707 1.00 21.33 ? 33 LYS A CD 1 33 UNP O57413 222 K
ATOM 268 C CE . LYS A 1 33 ? 23.852 26.662 24.892 1.00 23.50 ? 33 LYS A CE 1 33 UNP O57413 222 K
ATOM 269 N NZ . LYS A 1 33 ? 23.314 27.871 25.619 1.00 26.83 ? 33 LYS A NZ 1 33 UNP O57413 222 K
ATOM 270 N N . ARG A 1 34 ? 20.557 21.852 24.916 1.00 7.97 ? 34 ARG A N 1 34 UNP O57413 223 R
ATOM 271 C CA . ARG A 1 34 ? 20.131 21.465 23.571 1.00 7.28 ? 34 ARG A CA 1 34 UNP O57413 223 R
ATOM 272 C C . ARG A 1 34 ? 18.606 21.306 23.499 1.00 6.97 ? 34 ARG A C 1 34 UNP O57413 223 R
ATOM 273 O O . ARG A 1 34 ? 17.977 21.753 22.525 1.00 7.96 ? 34 ARG A O 1 34 UNP O57413 223 R
ATOM 274 C CB . ARG A 1 34 ? 20.786 20.139 23.194 1.00 9.27 ? 34 ARG A CB 1 34 UNP O57413 223 R
ATOM 275 C CG . ARG A 1 34 ? 20.477 19.715 21.751 1.00 10.19 ? 34 ARG A CG 1 34 UNP O57413 223 R
ATOM 276 C CD . ARG A 1 34 ? 21.319 18.510 21.339 1.00 12.21 ? 34 ARG A CD 1 34 UNP O57413 223 R
ATOM 277 N NE . ARG A 1 34 ? 20.990 18.048 19.992 1.00 12.73 ? 34 ARG A NE 1 34 UNP O57413 223 R
ATOM 278 C CZ . ARG A 1 34 ? 21.539 18.502 18.867 1.00 11.65 ? 34 ARG A CZ 1 34 UNP O57413 223 R
ATOM 279 N NH1 . ARG A 1 34 ? 22.468 19.463 18.881 1.00 13.12 ? 34 ARG A NH1 1 34 UNP O57413 223 R
ATOM 280 N NH2 . ARG A 1 34 ? 21.195 17.938 17.714 1.00 11.18 ? 34 ARG A NH2 1 34 UNP O57413 223 R
ATOM 281 N N . VAL A 1 35 ? 18.022 20.678 24.522 1.00 6.37 ? 35 VAL A N 1 35 UNP O57413 224 V
ATOM 282 C CA . VAL A 1 35 ? 16.566 20.495 24.537 1.00 6.52 ? 35 VAL A CA 1 35 UNP O57413 224 V
ATOM 283 C C . VAL A 1 35 ? 15.876 21.855 24.621 1.00 5.92 ? 35 VAL A C 1 35 UNP O57413 224 V
ATOM 284 O O . VAL A 1 35 ? 14.886 22.093 23.923 1.00 6.57 ? 35 VAL A O 1 35 UNP O57413 224 V
ATOM 285 C CB . VAL A 1 35 ? 16.117 19.571 25.684 1.00 6.12 ? 35 VAL A CB 1 35 UNP O57413 224 V
ATOM 286 C CG1 . VAL A 1 35 ? 14.604 19.565 25.769 1.00 8.54 ? 35 VAL A CG1 1 35 UNP O57413 224 V
ATOM 287 C CG2 . VAL A 1 35 ? 16.667 18.171 25.452 1.00 9.28 ? 35 VAL A CG2 1 35 UNP O57413 224 V
ATOM 288 N N . HIS A 1 36 ? 16.378 22.776 25.443 1.00 4.80 ? 36 HIS A N 1 36 UNP O57413 225 H
ATOM 289 C CA . HIS A 1 36 ? 15.742 24.092 25.482 1.00 4.94 ? 36 HIS A CA 1 36 UNP O57413 225 H
ATOM 290 C C . HIS A 1 36 ? 15.793 24.773 24.115 1.00 5.45 ? 36 HIS A C 1 36 UNP O57413 225 H
ATOM 291 O O . HIS A 1 36 ? 14.831 25.414 23.718 1.00 5.40 ? 36 HIS A O 1 36 UNP O57413 225 H
ATOM 292 C CB . HIS A 1 36 ? 16.394 24.988 26.553 1.00 5.72 ? 36 HIS A CB 1 36 UNP O57413 225 H
ATOM 293 C CG . HIS A 1 36 ? 15.886 24.707 27.936 1.00 5.46 ? 36 HIS A CG 1 36 UNP O57413 225 H
ATOM 294 N ND1 . HIS A 1 36 ? 15.407 25.702 28.766 1.00 7.20 ? 36 HIS A ND1 1 36 UNP O57413 225 H
ATOM 295 C CD2 . HIS A 1 36 ? 15.731 23.547 28.610 1.00 6.97 ? 36 HIS A CD2 1 36 UNP O57413 225 H
ATOM 296 C CE1 . HIS A 1 36 ? 14.983 25.163 29.894 1.00 6.95 ? 36 HIS A CE1 1 36 UNP O57413 225 H
ATOM 297 N NE2 . HIS A 1 36 ? 15.168 23.854 29.826 1.00 7.78 ? 36 HIS A NE2 1 36 UNP O57413 225 H
ATOM 298 N N . GLN A 1 37 ? 16.930 24.649 23.417 1.00 5.73 ? 37 GLN A N 1 37 UNP O57413 226 Q
ATOM 299 C CA . GLN A 1 37 ? 17.036 25.277 22.098 1.00 6.89 ? 37 GLN A CA 1 37 UNP O57413 226 Q
ATOM 300 C C . GLN A 1 37 ? 16.042 24.672 21.116 1.00 6.19 ? 37 GLN A C 1 37 UNP O57413 226 Q
ATOM 301 O O . GLN A 1 37 ? 15.492 25.385 20.259 1.00 6.35 ? 37 GLN A O 1 37 UNP O57413 226 Q
ATOM 302 C CB . GLN A 1 37 ? 18.455 25.171 21.544 1.00 8.58 ? 37 GLN A CB 1 37 UNP O57413 226 Q
ATOM 303 C CG . GLN A 1 37 ? 18.666 26.055 20.313 1.00 12.50 ? 37 GLN A CG 1 37 UNP O57413 226 Q
ATOM 304 C CD . GLN A 1 37 ? 20.054 26.007 19.718 1.00 13.66 ? 37 GLN A CD 1 37 UNP O57413 226 Q
ATOM 305 O OE1 . GLN A 1 37 ? 20.233 26.190 18.489 1.00 11.79 ? 37 GLN A OE1 1 37 UNP O57413 226 Q
ATOM 306 N NE2 . GLN A 1 37 ? 21.068 25.794 20.594 1.00 15.73 ? 37 GLN A NE2 1 37 UNP O57413 226 Q
ATOM 307 N N . MET A 1 38 ? 15.796 23.365 21.242 1.00 5.77 ? 38 MET A N 1 38 UNP O57413 227 M
ATOM 308 C CA . MET A 1 38 ? 14.803 22.724 20.389 1.00 5.79 ? 38 MET A CA 1 38 UNP O57413 227 M
ATOM 309 C C . MET A 1 38 ? 13.426 23.290 20.696 1.00 4.67 ? 38 MET A C 1 38 UNP O57413 227 M
ATOM 310 O O . MET A 1 38 ? 12.672 23.652 19.789 1.00 5.01 ? 38 MET A O 1 38 UNP O57413 227 M
ATOM 311 C CB . MET A 1 38 ? 14.803 21.226 20.619 1.00 8.14 ? 38 MET A CB 1 38 UNP O57413 227 M
ATOM 312 C CG . MET A 1 38 ? 16.094 20.606 20.232 1.00 12.31 ? 38 MET A CG 1 38 UNP O57413 227 M
ATOM 313 S SD . MET A 1 38 ? 16.226 18.918 20.806 1.00 16.55 ? 38 MET A SD 1 38 UNP O57413 227 M
ATOM 314 C CE . MET A 1 38 ? 17.557 18.315 19.694 1.00 17.45 ? 38 MET A CE 1 38 UNP O57413 227 M
ATOM 315 N N . VAL A 1 39 ? 13.099 23.397 21.981 1.00 5.11 ? 39 VAL A N 1 39 UNP O57413 228 V
ATOM 316 C CA . VAL A 1 39 ? 11.793 23.948 22.367 1.00 4.79 ? 39 VAL A CA 1 39 UNP O57413 228 V
ATOM 317 C C . VAL A 1 39 ? 11.621 25.373 21.866 1.00 4.98 ? 39 VAL A C 1 39 UNP O57413 228 V
ATOM 318 O O . VAL A 1 39 ? 10.549 25.734 21.409 1.00 4.97 ? 39 VAL A O 1 39 UNP O57413 228 V
ATOM 319 C CB . VAL A 1 39 ? 11.569 23.843 23.906 1.00 6.23 ? 39 VAL A CB 1 39 UNP O57413 228 V
ATOM 320 C CG1 . VAL A 1 39 ? 10.259 24.577 24.329 1.00 7.68 ? 39 VAL A CG1 1 39 UNP O57413 228 V
ATOM 321 C CG2 . VAL A 1 39 ? 11.498 22.346 24.299 1.00 8.26 ? 39 VAL A CG2 1 39 UNP O57413 228 V
ATOM 322 N N . SER A 1 40 ? 12.676 26.188 21.941 1.00 4.36 ? 40 SER A N 1 40 UNP O57413 229 S
ATOM 323 C CA . SER A 1 40 ? 12.559 27.580 21.485 1.00 4.82 ? 40 SER A CA 1 40 UNP O57413 229 S
ATOM 324 C C . SER A 1 40 ? 12.222 27.597 19.997 1.00 4.35 ? 40 SER A C 1 40 UNP O57413 229 S
ATOM 325 O O . SER A 1 40 ? 11.458 28.414 19.531 1.00 4.70 ? 40 SER A O 1 40 UNP O57413 229 S
ATOM 326 C CB . SER A 1 40 ? 13.882 28.324 21.753 1.00 6.65 ? 40 SER A CB 1 40 UNP O57413 229 S
ATOM 327 O OG . SER A 1 40 ? 14.145 28.395 23.151 1.00 11.82 ? 40 SER A OG 1 40 UNP O57413 229 S
ATOM 328 N N . ASN A 1 41 ? 12.825 26.685 19.239 1.00 4.12 ? 41 ASN A N 1 41 UNP O57413 230 N
ATOM 329 C CA . ASN A 1 41 ? 12.519 26.576 17.810 1.00 3.55 ? 41 ASN A CA 1 41 UNP O57413 230 N
ATOM 330 C C . ASN A 1 41 ? 11.086 26.068 17.544 1.00 3.78 ? 41 ASN A C 1 41 UNP O57413 230 N
ATOM 331 O O . ASN A 1 41 ? 10.401 26.583 16.669 1.00 3.63 ? 41 ASN A O 1 41 UNP O57413 230 N
ATOM 332 C CB . ASN A 1 41 ? 13.541 25.666 17.126 1.00 4.13 ? 41 ASN A CB 1 41 UNP O57413 230 N
ATOM 333 C CG . ASN A 1 41 ? 14.790 26.424 16.767 1.00 4.51 ? 41 ASN A CG 1 41 UNP O57413 230 N
ATOM 334 O OD1 . ASN A 1 41 ? 14.758 27.277 15.872 1.00 6.41 ? 41 ASN A OD1 1 41 UNP O57413 230 N
ATOM 335 N ND2 . ASN A 1 41 ? 15.902 26.127 17.446 1.00 5.67 ? 41 ASN A ND2 1 41 UNP O57413 230 N
ATOM 336 N N . ILE A 1 42 ? 10.618 25.103 18.324 1.00 3.59 ? 42 ILE A N 1 42 UNP O57413 231 I
ATOM 337 C CA . ILE A 1 42 ? 9.251 24.583 18.152 1.00 3.83 ? 42 ILE A CA 1 42 UNP O57413 231 I
ATOM 338 C C . ILE A 1 42 ? 8.269 25.718 18.470 1.00 4.13 ? 42 ILE A C 1 42 UNP O57413 231 I
ATOM 339 O O . ILE A 1 42 ? 7.305 25.949 17.745 1.00 4.70 ? 42 ILE A O 1 42 UNP O57413 231 I
ATOM 340 C CB . ILE A 1 42 ? 8.993 23.380 19.087 1.00 4.47 ? 42 ILE A CB 1 42 UNP O57413 231 I
ATOM 341 C CG1 . ILE A 1 42 ? 9.936 22.213 18.743 1.00 5.16 ? 42 ILE A CG1 1 42 UNP O57413 231 I
ATOM 342 C CG2 . ILE A 1 42 ? 7.546 22.928 18.942 1.00 4.85 ? 42 ILE A CG2 1 42 UNP O57413 231 I
ATOM 343 C CD1 . ILE A 1 42 ? 9.964 21.122 19.774 1.00 6.82 ? 42 ILE A CD1 1 42 UNP O57413 231 I
ATOM 344 N N . ASN A 1 43 ? 8.535 26.444 19.545 1.00 3.98 ? 43 ASN A N 1 43 UNP O57413 232 N
ATOM 345 C CA . ASN A 1 43 ? 7.662 27.544 19.882 1.00 4.70 ? 43 ASN A CA 1 43 UNP O57413 232 N
ATOM 346 C C . ASN A 1 43 ? 7.600 28.591 18.743 1.00 3.75 ? 43 ASN A C 1 43 UNP O57413 232 N
ATOM 347 O O . ASN A 1 43 ? 6.521 29.050 18.374 1.00 5.36 ? 43 ASN A O 1 43 UNP O57413 232 N
ATOM 348 C CB . ASN A 1 43 ? 8.165 28.193 21.155 1.00 6.36 ? 43 ASN A CB 1 43 UNP O57413 232 N
ATOM 349 C CG . ASN A 1 43 ? 7.282 29.278 21.594 1.00 9.39 ? 43 ASN A CG 1 43 UNP O57413 232 N
ATOM 350 O OD1 . ASN A 1 43 ? 6.184 29.019 22.086 1.00 10.78 ? 43 ASN A OD1 1 43 UNP O57413 232 N
ATOM 351 N ND2 . ASN A 1 43 ? 7.715 30.532 21.372 1.00 10.24 ? 43 ASN A ND2 1 43 UNP O57413 232 N
ATOM 352 N N . GLU A 1 44 ? 8.754 28.926 18.173 1.00 4.56 ? 44 GLU A N 1 44 UNP O57413 233 E
ATOM 353 C CA . GLU A 1 44 ? 8.786 29.888 17.078 1.00 4.86 ? 44 GLU A CA 1 44 UNP O57413 233 E
ATOM 354 C C . GLU A 1 44 ? 7.963 29.356 15.895 1.00 4.74 ? 44 GLU A C 1 44 UNP O57413 233 E
ATOM 355 O O . GLU A 1 44 ? 7.185 30.098 15.255 1.00 5.80 ? 44 GLU A O 1 44 UNP O57413 233 E
ATOM 356 C CB . GLU A 1 44 ? 10.229 30.121 16.640 1.00 5.08 ? 44 GLU A CB 1 44 UNP O57413 233 E
ATOM 357 C CG . GLU A 1 44 ? 10.423 30.860 15.329 1.00 6.56 ? 44 GLU A CG 1 44 UNP O57413 233 E
ATOM 358 C CD . GLU A 1 44 ? 9.875 32.264 15.322 1.00 7.86 ? 44 GLU A CD 1 44 UNP O57413 233 E
ATOM 359 O OE1 . GLU A 1 44 ? 9.619 32.856 16.380 1.00 7.14 ? 44 GLU A OE1 1 44 UNP O57413 233 E
ATOM 360 O OE2 . GLU A 1 44 ? 9.750 32.793 14.199 1.00 10.17 ? 44 GLU A OE2 1 44 UNP O57413 233 E
ATOM 361 N N . MET A 1 45 ? 8.145 28.076 15.572 1.00 4.61 ? 45 MET A N 1 45 UNP O57413 234 M
ATOM 362 C CA . MET A 1 45 ? 7.396 27.517 14.434 1.00 4.32 ? 45 MET A CA 1 45 UNP O57413 234 M
ATOM 363 C C . MET A 1 45 ? 5.898 27.454 14.639 1.00 3.78 ? 45 MET A C 1 45 UNP O57413 234 M
ATOM 364 O O . MET A 1 45 ? 5.127 27.499 13.677 1.00 5.05 ? 45 MET A O 1 45 UNP O57413 234 M
ATOM 365 C CB . MET A 1 45 ? 7.947 26.147 14.051 1.00 5.21 ? 45 MET A CB 1 45 UNP O57413 234 M
ATOM 366 C CG . MET A 1 45 ? 9.301 26.299 13.310 1.00 6.09 ? 45 MET A CG 1 45 UNP O57413 234 M
ATOM 367 S SD . MET A 1 45 ? 10.029 24.720 12.794 1.00 6.69 ? 45 MET A SD 1 45 UNP O57413 234 M
ATOM 368 C CE . MET A 1 45 ? 11.138 24.361 14.191 1.00 5.25 ? 45 MET A CE 1 45 UNP O57413 234 M
ATOM 369 N N . CYS A 1 46 ? 5.487 27.369 15.896 1.00 4.77 ? 46 CYS A N 1 46 UNP O57413 235 C
ATOM 370 C CA . CYS A 1 46 ? 4.065 27.331 16.191 1.00 5.84 ? 46 CYS A CA 1 46 UNP O57413 235 C
ATOM 371 C C . CYS A 1 46 ? 3.420 28.707 16.369 1.00 5.94 ? 46 CYS A C 1 46 UNP O57413 235 C
ATOM 372 O O . CYS A 1 46 ? 2.218 28.793 16.564 1.00 7.02 ? 46 CYS A O 1 46 UNP O57413 235 C
ATOM 373 C CB . CYS A 1 46 ? 3.809 26.469 17.422 1.00 4.99 ? 46 CYS A CB 1 46 UNP O57413 235 C
ATOM 374 S SG . CYS A 1 46 ? 4.095 24.704 17.115 1.00 6.84 ? 46 CYS A SG 1 46 UNP O57413 235 C
ATOM 375 N N . ARG A 1 47 ? 4.189 29.781 16.252 1.00 7.22 ? 47 ARG A N 1 47 UNP O57413 236 R
ATOM 376 C CA . ARG A 1 47 ? 3.558 31.081 16.449 1.00 8.88 ? 47 ARG A CA 1 47 UNP O57413 236 R
ATOM 377 C C . ARG A 1 47 ? 2.421 31.385 15.486 1.00 8.98 ? 47 ARG A C 1 47 UNP O57413 236 R
ATOM 378 O O . ARG A 1 47 ? 1.379 31.906 15.903 1.00 9.79 ? 47 ARG A O 1 47 UNP O57413 236 R
ATOM 379 C CB . ARG A 1 47 ? 4.577 32.197 16.376 1.00 11.72 ? 47 ARG A CB 1 47 UNP O57413 236 R
ATOM 380 C CG . ARG A 1 47 ? 5.511 32.246 17.506 1.00 13.69 ? 47 ARG A CG 1 47 UNP O57413 236 R
ATOM 381 C CD . ARG A 1 47 ? 6.402 33.468 17.347 1.00 15.35 ? 47 ARG A CD 1 47 UNP O57413 236 R
ATOM 382 N NE . ARG A 1 47 ? 6.813 33.626 15.956 1.00 18.06 ? 47 ARG A NE 1 47 UNP O57413 236 R
ATOM 383 C CZ . ARG A 1 47 ? 7.588 34.604 15.535 1.00 17.49 ? 47 ARG A CZ 1 47 UNP O57413 236 R
ATOM 384 N NH1 . ARG A 1 47 ? 8.028 35.476 16.415 1.00 15.51 ? 47 ARG A NH1 1 47 UNP O57413 236 R
ATOM 385 N NH2 . ARG A 1 47 ? 7.890 34.733 14.234 1.00 18.21 ? 47 ARG A NH2 1 47 UNP O57413 236 R
ATOM 386 N N . PRO A 1 48 ? 2.574 31.069 14.185 1.00 9.59 ? 48 PRO A N 1 48 UNP O57413 237 P
ATOM 387 C CA . PRO A 1 48 ? 1.450 31.365 13.284 1.00 9.77 ? 48 PRO A CA 1 48 UNP O57413 237 P
ATOM 388 C C . PRO A 1 48 ? 0.219 30.512 13.567 1.00 9.33 ? 48 PRO A C 1 48 UNP O57413 237 P
ATOM 389 O O . PRO A 1 48 ? -0.850 30.778 13.018 1.00 11.01 ? 48 PRO A O 1 48 UNP O57413 237 P
ATOM 390 C CB . PRO A 1 48 ? 2.024 31.087 11.888 1.00 9.96 ? 48 PRO A CB 1 48 UNP O57413 237 P
ATOM 391 C CG . PRO A 1 48 ? 3.493 31.336 12.073 1.00 9.29 ? 48 PRO A CG 1 48 UNP O57413 237 P
ATOM 392 C CD . PRO A 1 48 ? 3.793 30.716 13.425 1.00 9.59 ? 48 PRO A CD 1 48 UNP O57413 237 P
ATOM 393 N N . LEU A 1 49 ? 0.336 29.452 14.383 1.00 8.46 ? 49 LEU A N 1 49 UNP O57413 238 L
ATOM 394 C CA . LEU A 1 49 ? -0.824 28.645 14.728 1.00 8.55 ? 49 LEU A CA 1 49 UNP O57413 238 L
ATOM 395 C C . LEU A 1 49 ? -1.456 29.124 16.042 1.00 7.12 ? 49 LEU A C 1 49 UNP O57413 238 L
ATOM 396 O O . LEU A 1 49 ? -2.464 28.579 16.482 1.00 8.38 ? 49 LEU A O 1 49 UNP O57413 238 L
ATOM 397 C CB . LEU A 1 49 ? -0.415 27.164 14.893 1.00 7.77 ? 49 LEU A CB 1 49 UNP O57413 238 L
ATOM 398 C CG . LEU A 1 49 ? 0.216 26.503 13.648 1.00 7.98 ? 49 LEU A CG 1 49 UNP O57413 238 L
ATOM 399 C CD1 . LEU A 1 49 ? 0.426 25.030 13.934 1.00 9.19 ? 49 LEU A CD1 1 49 UNP O57413 238 L
ATOM 400 C CD2 . LEU A 1 49 ? -0.660 26.699 12.430 1.00 9.97 ? 49 LEU A CD2 1 49 UNP O57413 238 L
ATOM 401 N N . ASN A 1 50 ? -0.809 30.121 16.651 1.00 7.61 ? 50 ASN A N 1 50 UNP O57413 239 N
ATOM 402 C CA . ASN A 1 50 ? -1.223 30.662 17.945 1.00 7.76 ? 50 ASN A CA 1 50 UNP O57413 239 N
ATOM 403 C C . ASN A 1 50 ? -1.228 29.590 19.052 1.00 8.27 ? 50 ASN A C 1 50 UNP O57413 239 N
ATOM 404 O O . ASN A 1 50 ? -2.140 29.519 19.877 1.00 8.38 ? 50 ASN A O 1 50 UNP O57413 239 N
ATOM 405 C CB . ASN A 1 50 ? -2.580 31.391 17.852 1.00 9.15 ? 50 ASN A CB 1 50 UNP O57413 239 N
ATOM 406 C CG . ASN A 1 50 ? -2.742 32.451 18.936 1.00 9.82 ? 50 ASN A CG 1 50 UNP O57413 239 N
ATOM 407 O OD1 . ASN A 1 50 ? -1.800 32.821 19.650 1.00 10.34 ? 50 ASN A OD1 1 50 UNP O57413 239 N
ATOM 408 N ND2 . ASN A 1 50 ? -3.956 32.947 19.055 1.00 10.93 ? 50 ASN A ND2 1 50 UNP O57413 239 N
ATOM 409 N N . ILE A 1 51 ? -0.202 28.723 19.018 1.00 7.94 ? 51 ILE A N 1 51 UNP O57413 240 I
ATOM 410 C CA . ILE A 1 51 ? -0.043 27.709 20.049 1.00 7.34 ? 51 ILE A CA 1 51 UNP O57413 240 I
ATOM 411 C C . ILE A 1 51 ? 1.201 28.068 20.856 1.00 7.28 ? 51 ILE A C 1 51 UNP O57413 240 I
ATOM 412 O O . ILE A 1 51 ? 2.297 28.193 20.306 1.00 7.95 ? 51 ILE A O 1 51 UNP O57413 240 I
ATOM 413 C CB . ILE A 1 51 ? 0.183 26.278 19.490 1.00 6.85 ? 51 ILE A CB 1 51 UNP O57413 240 I
ATOM 414 C CG1 . ILE A 1 51 ? -0.963 25.866 18.573 1.00 7.67 ? 51 ILE A CG1 1 51 UNP O57413 240 I
ATOM 415 C CG2 . ILE A 1 51 ? 0.251 25.278 20.666 1.00 7.07 ? 51 ILE A CG2 1 51 UNP O57413 240 I
ATOM 416 C CD1 . ILE A 1 51 ? -0.659 24.540 17.865 1.00 9.02 ? 51 ILE A CD1 1 51 UNP O57413 240 I
ATOM 417 N N . ALA A 1 52 ? 1.020 28.282 22.158 1.00 6.54 ? 52 ALA A N 1 52 UNP O57413 241 A
ATOM 418 C CA . ALA A 1 52 ? 2.156 28.599 23.038 1.00 6.99 ? 52 ALA A CA 1 52 UNP O57413 241 A
ATOM 419 C C . ALA A 1 52 ? 2.729 27.269 23.500 1.00 6.62 ? 52 ALA A C 1 52 UNP O57413 241 A
ATOM 420 O O . ALA A 1 52 ? 2.025 26.466 24.112 1.00 6.37 ? 52 ALA A O 1 52 UNP O57413 241 A
ATOM 421 C CB . ALA A 1 52 ? 1.671 29.433 24.259 1.00 7.26 ? 52 ALA A CB 1 52 UNP O57413 241 A
ATOM 422 N N . ILE A 1 53 ? 4.008 27.072 23.250 1.00 7.07 ? 53 ILE A N 1 53 UNP O57413 242 I
ATOM 423 C CA . ILE A 1 53 ? 4.695 25.819 23.575 1.00 7.10 ? 53 ILE A CA 1 53 UNP O57413 242 I
ATOM 424 C C . ILE A 1 53 ? 5.560 26.000 24.823 1.00 7.59 ? 53 ILE A C 1 53 UNP O57413 242 I
ATOM 425 O O . ILE A 1 53 ? 6.344 26.953 24.900 1.00 9.24 ? 53 ILE A O 1 53 UNP O57413 242 I
ATOM 426 C CB . ILE A 1 53 ? 5.646 25.418 22.391 1.00 7.79 ? 53 ILE A CB 1 53 UNP O57413 242 I
ATOM 427 C CG1 . ILE A 1 53 ? 4.876 25.292 21.069 1.00 9.02 ? 53 ILE A CG1 1 53 UNP O57413 242 I
ATOM 428 C CG2 . ILE A 1 53 ? 6.375 24.105 22.712 1.00 8.65 ? 53 ILE A CG2 1 53 UNP O57413 242 I
ATOM 429 C CD1 . ILE A 1 53 ? 3.904 24.122 21.026 1.00 8.97 ? 53 ILE A CD1 1 53 UNP O57413 242 I
ATOM 430 N N . THR A 1 54 ? 5.385 25.132 25.802 1.00 6.59 ? 54 THR A N 1 54 UNP O57413 243 T
ATOM 431 C CA . THR A 1 54 ? 6.241 25.166 26.975 1.00 7.85 ? 54 THR A CA 1 54 UNP O57413 243 T
ATOM 432 C C . THR A 1 54 ? 6.801 23.787 27.255 1.00 8.56 ? 54 THR A C 1 54 UNP O57413 243 T
ATOM 433 O O . THR A 1 54 ? 6.202 22.770 26.851 1.00 9.49 ? 54 THR A O 1 54 UNP O57413 243 T
ATOM 434 C CB . THR A 1 54 ? 5.508 25.651 28.241 1.00 9.13 ? 54 THR A CB 1 54 UNP O57413 243 T
ATOM 435 O OG1 . THR A 1 54 ? 4.241 24.992 28.391 1.00 9.53 ? 54 THR A OG1 1 54 UNP O57413 243 T
ATOM 436 C CG2 . THR A 1 54 ? 5.355 27.161 28.205 1.00 11.23 ? 54 THR A CG2 1 54 UNP O57413 243 T
ATOM 437 N N . LEU A 1 55 ? 7.963 23.750 27.908 1.00 6.97 ? 55 LEU A N 1 55 UNP O57413 244 L
ATOM 438 C CA . LEU A 1 55 ? 8.601 22.507 28.345 1.00 7.28 ? 55 LEU A CA 1 55 UNP O57413 244 L
ATOM 439 C C . LEU A 1 55 ? 8.134 22.252 29.769 1.00 7.67 ? 55 LEU A C 1 55 UNP O57413 244 L
ATOM 440 O O . LEU A 1 55 ? 8.656 22.843 30.713 1.00 9.20 ? 55 LEU A O 1 55 UNP O57413 244 L
ATOM 441 C CB . LEU A 1 55 ? 10.135 22.646 28.294 1.00 7.56 ? 55 LEU A CB 1 55 UNP O57413 244 L
ATOM 442 C CG . LEU A 1 55 ? 10.929 21.399 28.701 1.00 8.48 ? 55 LEU A CG 1 55 UNP O57413 244 L
ATOM 443 C CD1 . LEU A 1 55 ? 10.580 20.257 27.766 1.00 9.78 ? 55 LEU A CD1 1 55 UNP O57413 244 L
ATOM 444 C CD2 . LEU A 1 55 ? 12.410 21.698 28.648 1.00 9.93 ? 55 LEU A CD2 1 55 UNP O57413 244 L
ATOM 445 N N . ALA A 1 56 ? 7.113 21.415 29.928 1.00 7.07 ? 56 ALA A N 1 56 UNP O57413 245 A
ATOM 446 C CA . ALA A 1 56 ? 6.588 21.082 31.255 1.00 7.34 ? 56 ALA A CA 1 56 UNP O57413 245 A
ATOM 447 C C . ALA A 1 56 ? 7.507 20.132 31.996 1.00 8.03 ? 56 ALA A C 1 56 UNP O57413 245 A
ATOM 448 O O . ALA A 1 56 ? 7.577 20.161 33.216 1.00 8.91 ? 56 ALA A O 1 56 UNP O57413 245 A
ATOM 449 C CB . ALA A 1 56 ? 5.203 20.431 31.112 1.00 8.82 ? 56 ALA A CB 1 56 UNP O57413 245 A
ATOM 450 N N . LEU A 1 57 ? 8.203 19.266 31.275 1.00 8.29 ? 57 LEU A N 1 57 UNP O57413 246 L
ATOM 451 C CA . LEU A 1 57 ? 9.025 18.254 31.895 1.00 9.22 ? 57 LEU A CA 1 57 UNP O57413 246 L
ATOM 452 C C . LEU A 1 57 ? 10.143 17.761 31.017 1.00 8.83 ? 57 LEU A C 1 57 UNP O57413 246 L
ATOM 453 O O . LEU A 1 57 ? 9.914 17.523 29.822 1.00 9.10 ? 57 LEU A O 1 57 UNP O57413 246 L
ATOM 454 C CB . LEU A 1 57 ? 8.136 17.062 32.222 1.00 10.96 ? 57 LEU A CB 1 57 UNP O57413 246 L
ATOM 455 C CG . LEU A 1 57 ? 8.652 15.841 32.945 1.00 13.57 ? 57 LEU A CG 1 57 UNP O57413 246 L
ATOM 456 C CD1 . LEU A 1 57 ? 8.988 16.273 34.367 1.00 14.96 ? 57 LEU A CD1 1 57 UNP O57413 246 L
ATOM 457 C CD2 . LEU A 1 57 ? 7.560 14.768 32.960 1.00 14.49 ? 57 LEU A CD2 1 57 UNP O57413 246 L
ATOM 458 N N . LEU A 1 58 ? 11.340 17.615 31.579 1.00 8.55 ? 58 LEU A N 1 58 UNP O57413 247 L
ATOM 459 C CA . LEU A 1 58 ? 12.503 17.059 30.871 1.00 8.84 ? 58 LEU A CA 1 58 UNP O57413 247 L
ATOM 460 C C . LEU A 1 58 ? 12.920 15.856 31.696 1.00 9.37 ? 58 LEU A C 1 58 UNP O57413 247 L
ATOM 461 O O . LEU A 1 58 ? 13.148 15.960 32.910 1.00 10.46 ? 58 LEU A O 1 58 UNP O57413 247 L
ATOM 462 C CB . LEU A 1 58 ? 13.666 18.067 30.792 1.00 9.67 ? 58 LEU A CB 1 58 UNP O57413 247 L
ATOM 463 C CG . LEU A 1 58 ? 15.000 17.462 30.356 1.00 10.08 ? 58 LEU A CG 1 58 UNP O57413 247 L
ATOM 464 C CD1 . LEU A 1 58 ? 14.868 16.894 28.936 1.00 10.24 ? 58 LEU A CD1 1 58 UNP O57413 247 L
ATOM 465 C CD2 . LEU A 1 58 ? 16.121 18.532 30.384 1.00 11.60 ? 58 LEU A CD2 1 58 UNP O57413 247 L
ATOM 466 N N . ASP A 1 59 ? 12.976 14.694 31.076 1.00 8.00 ? 59 ASP A N 1 59 UNP O57413 248 D
ATOM 467 C CA . ASP A 1 59 ? 13.381 13.482 31.771 1.00 7.84 ? 59 ASP A CA 1 59 UNP O57413 248 D
ATOM 468 C C . ASP A 1 59 ? 14.540 12.902 30.991 1.00 8.60 ? 59 ASP A C 1 59 UNP O57413 248 D
ATOM 469 O O . ASP A 1 59 ? 14.376 12.541 29.829 1.00 8.16 ? 59 ASP A O 1 59 UNP O57413 248 D
ATOM 470 C CB . ASP A 1 59 ? 12.213 12.487 31.846 1.00 9.71 ? 59 ASP A CB 1 59 UNP O57413 248 D
ATOM 471 C CG . ASP A 1 59 ? 12.569 11.204 32.571 1.00 12.33 ? 59 ASP A CG 1 59 UNP O57413 248 D
ATOM 472 O OD1 . ASP A 1 59 ? 13.504 11.207 33.396 1.00 15.32 ? 59 ASP A OD1 1 59 UNP O57413 248 D
ATOM 473 O OD2 . ASP A 1 59 ? 11.899 10.176 32.340 1.00 13.79 ? 59 ASP A OD2 1 59 UNP O57413 248 D
ATOM 474 N N . VAL A 1 60 ? 15.716 12.815 31.602 1.00 8.66 ? 60 VAL A N 1 60 UNP O57413 249 V
ATOM 475 C CA . VAL A 1 60 ? 16.903 12.283 30.927 1.00 9.30 ? 60 VAL A CA 1 60 UNP O57413 249 V
ATOM 476 C C . VAL A 1 60 ? 17.200 10.941 31.557 1.00 9.57 ? 60 VAL A C 1 60 UNP O57413 249 V
ATOM 477 O O . VAL A 1 60 ? 17.354 10.851 32.776 1.00 9.83 ? 60 VAL A O 1 60 UNP O57413 249 V
ATOM 478 C CB . VAL A 1 60 ? 18.087 13.232 31.126 1.00 9.97 ? 60 VAL A CB 1 60 UNP O57413 249 V
ATOM 479 C CG1 . VAL A 1 60 ? 19.362 12.660 30.504 1.00 10.27 ? 60 VAL A CG1 1 60 UNP O57413 249 V
ATOM 480 C CG2 . VAL A 1 60 ? 17.712 14.581 30.546 1.00 9.75 ? 60 VAL A CG2 1 60 UNP O57413 249 V
ATOM 481 N N . TRP A 1 61 ? 17.237 9.899 30.735 1.00 9.76 ? 61 TRP A N 1 61 UNP O57413 250 W
ATOM 482 C CA . TRP A 1 61 ? 17.482 8.527 31.204 1.00 9.52 ? 61 TRP A CA 1 61 UNP O57413 250 W
ATOM 483 C C . TRP A 1 61 ? 18.984 8.300 31.356 1.00 11.20 ? 61 TRP A C 1 61 UNP O57413 250 W
ATOM 484 O O . TRP A 1 61 ? 19.619 7.626 30.551 1.00 11.73 ? 61 TRP A O 1 61 UNP O57413 250 W
ATOM 485 C CB . TRP A 1 61 ? 16.854 7.526 30.221 1.00 9.52 ? 61 TRP A CB 1 61 UNP O57413 250 W
ATOM 486 C CG . TRP A 1 61 ? 15.342 7.555 30.202 1.00 7.72 ? 61 TRP A CG 1 61 UNP O57413 250 W
ATOM 487 C CD1 . TRP A 1 61 ? 14.495 8.212 31.089 1.00 8.27 ? 61 TRP A CD1 1 61 UNP O57413 250 W
ATOM 488 C CD2 . TRP A 1 61 ? 14.493 6.843 29.309 1.00 7.55 ? 61 TRP A CD2 1 61 UNP O57413 250 W
ATOM 489 N NE1 . TRP A 1 61 ? 13.183 7.929 30.787 1.00 8.41 ? 61 TRP A NE1 1 61 UNP O57413 250 W
ATOM 490 C CE2 . TRP A 1 61 ? 13.148 7.089 29.701 1.00 7.46 ? 61 TRP A CE2 1 61 UNP O57413 250 W
ATOM 491 C CE3 . TRP A 1 61 ? 14.732 5.998 28.208 1.00 8.12 ? 61 TRP A CE3 1 61 UNP O57413 250 W
ATOM 492 C CZ2 . TRP A 1 61 ? 12.054 6.522 29.031 1.00 7.94 ? 61 TRP A CZ2 1 61 UNP O57413 250 W
ATOM 493 C CZ3 . TRP A 1 61 ? 13.666 5.453 27.557 1.00 7.86 ? 61 TRP A CZ3 1 61 UNP O57413 250 W
ATOM 494 C CH2 . TRP A 1 61 ? 12.333 5.704 27.955 1.00 7.84 ? 61 TRP A CH2 1 61 UNP O57413 250 W
ATOM 495 N N . SER A 1 62 ? 19.535 8.887 32.421 1.00 12.25 ? 62 SER A N 1 62 UNP O57413 251 S
ATOM 496 C CA . SER A 1 62 ? 20.958 8.838 32.714 1.00 14.27 ? 62 SER A CA 1 62 UNP O57413 251 S
ATOM 497 C C . SER A 1 62 ? 21.503 7.496 33.195 1.00 15.33 ? 62 SER A C 1 62 UNP O57413 251 S
ATOM 498 O O . SER A 1 62 ? 22.709 7.308 33.178 1.00 16.63 ? 62 SER A O 1 62 UNP O57413 251 S
ATOM 499 C CB . SER A 1 62 ? 21.287 9.896 33.757 1.00 14.20 ? 62 SER A CB 1 62 UNP O57413 251 S
ATOM 500 O OG . SER A 1 62 ? 20.467 9.735 34.894 1.00 16.40 ? 62 SER A OG 1 62 UNP O57413 251 S
ATOM 501 N N . GLU A 1 63 ? 20.624 6.602 33.625 1.00 16.11 ? 63 GLU A N 1 63 UNP O57413 252 E
ATOM 502 C CA . GLU A 1 63 ? 21.052 5.294 34.133 1.00 18.02 ? 63 GLU A CA 1 63 UNP O57413 252 E
ATOM 503 C C . GLU A 1 63 ? 20.834 4.178 33.105 1.00 17.85 ? 63 GLU A C 1 63 UNP O57413 252 E
ATOM 504 O O . GLU A 1 63 ? 21.769 3.417 32.779 1.00 18.43 ? 63 GLU A O 1 63 UNP O57413 252 E
ATOM 505 C CB . GLU A 1 63 ? 20.286 4.979 35.430 1.00 21.19 ? 63 GLU A CB 1 63 UNP O57413 252 E
ATOM 506 C CG . GLU A 1 63 ? 20.601 3.617 36.082 1.00 25.38 ? 63 GLU A CG 1 63 UNP O57413 252 E
ATOM 507 C CD . GLU A 1 63 ? 19.561 3.202 37.140 1.00 27.97 ? 63 GLU A CD 1 63 UNP O57413 252 E
ATOM 508 O OE1 . GLU A 1 63 ? 19.682 2.086 37.698 1.00 29.85 ? 63 GLU A OE1 1 63 UNP O57413 252 E
ATOM 509 O OE2 . GLU A 1 63 ? 18.618 3.987 37.423 1.00 30.02 ? 63 GLU A OE2 1 63 UNP O57413 252 E
ATOM 510 N N . LYS A 1 64 ? 19.609 4.084 32.591 1.00 16.62 ? 64 LYS A N 1 64 UNP O57413 253 K
ATOM 511 C CA . LYS A 1 64 ? 19.259 3.052 31.610 1.00 15.32 ? 64 LYS A CA 1 64 UNP O57413 253 K
ATOM 512 C C . LYS A 1 64 ? 17.960 3.408 30.901 1.00 14.01 ? 64 LYS A C 1 64 UNP O57413 253 K
ATOM 513 O O . LYS A 1 64 ? 17.222 4.279 31.367 1.00 14.34 ? 64 LYS A O 1 64 UNP O57413 253 K
ATOM 514 C CB . LYS A 1 64 ? 19.064 1.715 32.324 1.00 17.12 ? 64 LYS A CB 1 64 UNP O57413 253 K
ATOM 515 C CG . LYS A 1 64 ? 17.866 1.666 33.262 1.00 19.15 ? 64 LYS A CG 1 64 UNP O57413 253 K
ATOM 516 C CD . LYS A 1 64 ? 17.812 0.304 33.922 1.00 22.29 ? 64 LYS A CD 1 64 UNP O57413 253 K
ATOM 517 C CE . LYS A 1 64 ? 16.540 0.085 34.702 1.00 23.64 ? 64 LYS A CE 1 64 UNP O57413 253 K
ATOM 518 N NZ . LYS A 1 64 ? 16.606 -1.279 35.352 1.00 26.26 ? 64 LYS A NZ 1 64 UNP O57413 253 K
ATOM 519 N N . ASP A 1 65 ? 17.682 2.749 29.778 1.00 12.48 ? 65 ASP A N 1 65 UNP O57413 254 D
ATOM 520 C CA . ASP A 1 65 ? 16.417 2.956 29.077 1.00 12.07 ? 65 ASP A CA 1 65 UNP O57413 254 D
ATOM 521 C C . ASP A 1 65 ? 15.311 2.242 29.840 1.00 11.33 ? 65 ASP A C 1 65 UNP O57413 254 D
ATOM 522 O O . ASP A 1 65 ? 15.496 1.095 30.301 1.00 12.42 ? 65 ASP A O 1 65 UNP O57413 254 D
ATOM 523 C CB . ASP A 1 65 ? 16.466 2.377 27.676 1.00 12.26 ? 65 ASP A CB 1 65 UNP O57413 254 D
ATOM 524 C CG . ASP A 1 65 ? 17.279 3.228 26.730 1.00 12.28 ? 65 ASP A CG 1 65 UNP O57413 254 D
ATOM 525 O OD1 . ASP A 1 65 ? 17.762 2.681 25.719 1.00 12.61 ? 65 ASP A OD1 1 65 UNP O57413 254 D
ATOM 526 O OD2 . ASP A 1 65 ? 17.417 4.434 26.996 1.00 12.97 ? 65 ASP A OD2 1 65 UNP O57413 254 D
ATOM 527 N N . PHE A 1 66 ? 14.161 2.884 29.949 1.00 10.22 ? 66 PHE A N 1 66 UNP O57413 255 F
ATOM 528 C CA . PHE A 1 66 ? 13.021 2.323 30.648 1.00 10.52 ? 66 PHE A CA 1 66 UNP O57413 255 F
ATOM 529 C C . PHE A 1 66 ? 12.038 1.575 29.742 1.00 11.19 ? 66 PHE A C 1 66 UNP O57413 255 F
ATOM 530 O O . PHE A 1 66 ? 11.047 1.005 30.214 1.00 11.92 ? 66 PHE A O 1 66 UNP O57413 255 F
ATOM 531 C CB . PHE A 1 66 ? 12.341 3.438 31.474 1.00 10.70 ? 66 PHE A CB 1 66 UNP O57413 255 F
ATOM 532 C CG . PHE A 1 66 ? 13.165 3.859 32.666 1.00 12.33 ? 66 PHE A CG 1 66 UNP O57413 255 F
ATOM 533 C CD1 . PHE A 1 66 ? 13.691 5.131 32.755 1.00 13.67 ? 66 PHE A CD1 1 66 UNP O57413 255 F
ATOM 534 C CD2 . PHE A 1 66 ? 13.485 2.933 33.660 1.00 14.39 ? 66 PHE A CD2 1 66 UNP O57413 255 F
ATOM 535 C CE1 . PHE A 1 66 ? 14.537 5.495 33.817 1.00 15.59 ? 66 PHE A CE1 1 66 UNP O57413 255 F
ATOM 536 C CE2 . PHE A 1 66 ? 14.333 3.288 34.722 1.00 15.76 ? 66 PHE A CE2 1 66 UNP O57413 255 F
ATOM 537 C CZ . PHE A 1 66 ? 14.856 4.578 34.790 1.00 15.73 ? 66 PHE A CZ 1 66 UNP O57413 255 F
ATOM 538 N N . ILE A 1 67 ? 12.304 1.619 28.435 1.00 9.97 ? 67 ILE A N 1 67 UNP O57413 256 I
ATOM 539 C CA . ILE A 1 67 ? 11.544 0.871 27.443 1.00 10.56 ? 67 ILE A CA 1 67 UNP O57413 256 I
ATOM 540 C C . ILE A 1 67 ? 12.569 0.306 26.482 1.00 11.00 ? 67 ILE A C 1 67 UNP O57413 256 I
ATOM 541 O O . ILE A 1 67 ? 13.712 0.738 26.492 1.00 10.79 ? 67 ILE A O 1 67 UNP O57413 256 I
ATOM 542 C CB . ILE A 1 67 ? 10.530 1.727 26.628 1.00 9.76 ? 67 ILE A CB 1 67 UNP O57413 256 I
ATOM 543 C CG1 . ILE A 1 67 ? 11.262 2.713 25.708 1.00 8.83 ? 67 ILE A CG1 1 67 UNP O57413 256 I
ATOM 544 C CG2 . ILE A 1 67 ? 9.570 2.414 27.555 1.00 10.58 ? 67 ILE A CG2 1 67 UNP O57413 256 I
ATOM 545 C CD1 . ILE A 1 67 ? 10.302 3.474 24.796 1.00 9.42 ? 67 ILE A CD1 1 67 UNP O57413 256 I
ATOM 546 N N . THR A 1 68 ? 12.142 -0.652 25.667 1.00 11.98 ? 68 THR A N 1 68 UNP O57413 257 T
ATOM 547 C CA . THR A 1 68 ? 13.031 -1.233 24.694 1.00 13.18 ? 68 THR A CA 1 68 UNP O57413 257 T
ATOM 548 C C . THR A 1 68 ? 13.058 -0.316 23.450 1.00 10.71 ? 68 THR A C 1 68 UNP O57413 257 T
ATOM 549 O O . THR A 1 68 ? 12.192 -0.450 22.575 1.00 11.65 ? 68 THR A O 1 68 UNP O57413 257 T
ATOM 550 C CB . THR A 1 68 ? 12.535 -2.638 24.313 1.00 14.58 ? 68 THR A CB 1 68 UNP O57413 257 T
ATOM 551 O OG1 . THR A 1 68 ? 12.222 -3.390 25.505 1.00 18.40 ? 68 THR A OG1 1 68 UNP O57413 257 T
ATOM 552 C CG2 . THR A 1 68 ? 13.608 -3.352 23.531 1.00 16.88 ? 68 THR A CG2 1 68 UNP O57413 257 T
ATOM 553 N N . VAL A 1 69 ? 14.000 0.630 23.407 1.00 11.00 ? 69 VAL A N 1 69 UNP O57413 258 V
ATOM 554 C CA . VAL A 1 69 ? 14.116 1.541 22.268 1.00 10.05 ? 69 VAL A CA 1 69 UNP O57413 258 V
ATOM 555 C C . VAL A 1 69 ? 14.661 0.567 21.240 1.00 11.24 ? 69 VAL A C 1 69 UNP O57413 258 V
ATOM 556 O O . VAL A 1 69 ? 15.536 -0.264 21.559 1.00 13.72 ? 69 VAL A O 1 69 UNP O57413 258 V
ATOM 557 C CB . VAL A 1 69 ? 15.074 2.747 22.557 1.00 10.46 ? 69 VAL A CB 1 69 UNP O57413 258 V
ATOM 558 C CG1 . VAL A 1 69 ? 15.009 3.797 21.431 1.00 11.57 ? 69 VAL A CG1 1 69 UNP O57413 258 V
ATOM 559 C CG2 . VAL A 1 69 ? 14.636 3.433 23.853 1.00 10.86 ? 69 VAL A CG2 1 69 UNP O57413 258 V
ATOM 560 N N . GLN A 1 70 ? 14.095 0.587 20.056 1.00 7.96 ? 70 GLN A N 1 70 UNP O57413 259 Q
ATOM 561 C CA . GLN A 1 70 ? 14.510 -0.359 19.024 1.00 7.33 ? 70 GLN A CA 1 70 UNP O57413 259 Q
ATOM 562 C C . GLN A 1 70 ? 14.396 0.244 17.638 1.00 7.47 ? 70 GLN A C 1 70 UNP O57413 259 Q
ATOM 563 O O . GLN A 1 70 ? 13.906 1.366 17.459 1.00 7.63 ? 70 GLN A O 1 70 UNP O57413 259 Q
ATOM 564 C CB . GLN A 1 70 ? 13.664 -1.628 19.155 1.00 7.48 ? 70 GLN A CB 1 70 UNP O57413 259 Q
ATOM 565 C CG . GLN A 1 70 ? 12.170 -1.387 19.152 1.00 7.97 ? 70 GLN A CG 1 70 UNP O57413 259 Q
ATOM 566 C CD . GLN A 1 70 ? 11.413 -2.645 19.496 1.00 7.95 ? 70 GLN A CD 1 70 UNP O57413 259 Q
ATOM 567 O OE1 . GLN A 1 70 ? 11.191 -3.481 18.624 1.00 7.75 ? 70 GLN A OE1 1 70 UNP O57413 259 Q
ATOM 568 N NE2 . GLN A 1 70 ? 11.033 -2.796 20.760 1.00 9.86 ? 70 GLN A NE2 1 70 UNP O57413 259 Q
ATOM 569 N N . ALA A 1 71 ? 14.796 -0.531 16.633 1.00 8.08 ? 71 ALA A N 1 71 UNP O57413 260 A
ATOM 570 C CA . ALA A 1 71 ? 14.857 -0.010 15.276 1.00 8.45 ? 71 ALA A CA 1 71 UNP O57413 260 A
ATOM 571 C C . ALA A 1 71 ? 13.545 0.369 14.644 1.00 8.42 ? 71 ALA A C 1 71 UNP O57413 260 A
ATOM 572 O O . ALA A 1 71 ? 13.498 1.348 13.892 1.00 9.17 ? 71 ALA A O 1 71 UNP O57413 260 A
ATOM 573 C CB . ALA A 1 71 ? 15.658 -0.987 14.362 1.00 9.58 ? 71 ALA A CB 1 71 UNP O57413 260 A
ATOM 574 N N . ASP A 1 72 ? 12.464 -0.351 14.912 1.00 8.27 ? 72 ASP A N 1 72 UNP O57413 261 D
ATOM 575 C CA . ASP A 1 72 ? 11.194 0.049 14.320 1.00 8.01 ? 72 ASP A CA 1 72 UNP O57413 261 D
ATOM 576 C C . ASP A 1 72 ? 10.602 1.222 15.114 1.00 7.68 ? 72 ASP A C 1 72 UNP O57413 261 D
ATOM 577 O O . ASP A 1 72 ? 10.231 1.098 16.302 1.00 8.31 ? 72 ASP A O 1 72 UNP O57413 261 D
ATOM 578 C CB . ASP A 1 72 ? 10.227 -1.134 14.280 1.00 9.38 ? 72 ASP A CB 1 72 UNP O57413 261 D
ATOM 579 C CG . ASP A 1 72 ? 8.969 -0.808 13.540 1.00 10.05 ? 72 ASP A CG 1 72 UNP O57413 261 D
ATOM 580 O OD1 . ASP A 1 72 ? 9.056 -0.575 12.322 1.00 12.38 ? 72 ASP A OD1 1 72 UNP O57413 261 D
ATOM 581 O OD2 . ASP A 1 72 ? 7.906 -0.738 14.172 1.00 11.95 ? 72 ASP A OD2 1 72 UNP O57413 261 D
ATOM 582 N N . ALA A 1 73 ? 10.510 2.371 14.458 1.00 7.24 ? 73 ALA A N 1 73 UNP O57413 262 A
ATOM 583 C CA . ALA A 1 73 ? 10.037 3.558 15.140 1.00 6.92 ? 73 ALA A CA 1 73 UNP O57413 262 A
ATOM 584 C C . ALA A 1 73 ? 8.608 3.426 15.646 1.00 6.75 ? 73 ALA A C 1 73 UNP O57413 262 A
ATOM 585 O O . ALA A 1 73 ? 8.333 3.817 16.778 1.00 5.95 ? 73 ALA A O 1 73 UNP O57413 262 A
ATOM 586 C CB . ALA A 1 73 ? 10.201 4.813 14.229 1.00 7.03 ? 73 ALA A CB 1 73 UNP O57413 262 A
ATOM 587 N N . PRO A 1 74 ? 7.685 2.865 14.844 1.00 7.07 ? 74 PRO A N 1 74 UNP O57413 263 P
ATOM 588 C CA . PRO A 1 74 ? 6.300 2.739 15.348 1.00 7.57 ? 74 PRO A CA 1 74 UNP O57413 263 P
ATOM 589 C C . PRO A 1 74 ? 6.211 1.850 16.590 1.00 6.81 ? 74 PRO A C 1 74 UNP O57413 263 P
ATOM 590 O O . PRO A 1 74 ? 5.455 2.143 17.515 1.00 7.65 ? 74 PRO A O 1 74 UNP O57413 263 P
ATOM 591 C CB . PRO A 1 74 ? 5.520 2.192 14.146 1.00 8.10 ? 74 PRO A CB 1 74 UNP O57413 263 P
ATOM 592 C CG . PRO A 1 74 ? 6.298 2.728 12.984 1.00 9.64 ? 74 PRO A CG 1 74 UNP O57413 263 P
ATOM 593 C CD . PRO A 1 74 ? 7.762 2.575 13.394 1.00 8.21 ? 74 PRO A CD 1 74 UNP O57413 263 P
ATOM 594 N N . THR A 1 75 ? 7.004 0.778 16.621 1.00 7.19 ? 75 THR A N 1 75 UNP O57413 264 T
ATOM 595 C CA . THR A 1 75 ? 7.017 -0.136 17.772 1.00 7.14 ? 75 THR A CA 1 75 UNP O57413 264 T
ATOM 596 C C . THR A 1 75 ? 7.552 0.610 18.995 1.00 6.38 ? 75 THR A C 1 75 UNP O57413 264 T
ATOM 597 O O . THR A 1 75 ? 6.964 0.554 20.088 1.00 6.81 ? 75 THR A O 1 75 UNP O57413 264 T
ATOM 598 C CB . THR A 1 75 ? 7.851 -1.394 17.494 1.00 8.25 ? 75 THR A CB 1 75 UNP O57413 264 T
ATOM 599 O OG1 . THR A 1 75 ? 7.289 -2.057 16.349 1.00 8.31 ? 75 THR A OG1 1 75 UNP O57413 264 T
ATOM 600 C CG2 . THR A 1 75 ? 7.780 -2.350 18.646 1.00 8.72 ? 75 THR A CG2 1 75 UNP O57413 264 T
ATOM 601 N N . THR A 1 76 ? 8.645 1.357 18.814 1.00 6.04 ? 76 THR A N 1 76 UNP O57413 265 T
ATOM 602 C CA . THR A 1 76 ? 9.207 2.145 19.904 1.00 5.55 ? 76 THR A CA 1 76 UNP O57413 265 T
ATOM 603 C C . THR A 1 76 ? 8.180 3.181 20.377 1.00 5.82 ? 76 THR A C 1 76 UNP O57413 265 T
ATOM 604 O O . THR A 1 76 ? 8.047 3.413 21.588 1.00 6.57 ? 76 THR A O 1 76 UNP O57413 265 T
ATOM 605 C CB . THR A 1 76 ? 10.475 2.854 19.427 1.00 5.79 ? 76 THR A CB 1 76 UNP O57413 265 T
ATOM 606 O OG1 . THR A 1 76 ? 11.467 1.845 19.130 1.00 6.22 ? 76 THR A OG1 1 76 UNP O57413 265 T
ATOM 607 C CG2 . THR A 1 76 ? 11.016 3.847 20.512 1.00 6.22 ? 76 THR A CG2 1 76 UNP O57413 265 T
ATOM 608 N N . ALA A 1 77 ? 7.460 3.813 19.458 1.00 6.00 ? 77 ALA A N 1 77 UNP O57413 266 A
ATOM 609 C CA . ALA A 1 77 ? 6.450 4.798 19.840 1.00 6.05 ? 77 ALA A CA 1 77 UNP O57413 266 A
ATOM 610 C C . ALA A 1 77 ? 5.348 4.172 20.703 1.00 5.98 ? 77 ALA A C 1 77 UNP O57413 266 A
ATOM 611 O O . ALA A 1 77 ? 4.858 4.781 21.644 1.00 5.97 ? 77 ALA A O 1 77 UNP O57413 266 A
ATOM 612 C CB . ALA A 1 77 ? 5.852 5.464 18.574 1.00 6.79 ? 77 ALA A CB 1 77 UNP O57413 266 A
ATOM 613 N N . GLY A 1 78 ? 4.926 2.969 20.362 1.00 6.25 ? 78 GLY A N 1 78 UNP O57413 267 G
ATOM 614 C CA . GLY A 1 78 ? 3.887 2.306 21.136 1.00 6.51 ? 78 GLY A CA 1 78 UNP O57413 267 G
ATOM 615 C C . GLY A 1 78 ? 4.363 1.983 22.541 1.00 6.66 ? 78 GLY A C 1 78 UNP O57413 267 G
ATOM 616 O O . GLY A 1 78 ? 3.622 2.168 23.513 1.00 8.15 ? 78 GLY A O 1 78 UNP O57413 267 G
ATOM 617 N N . LEU A 1 79 ? 5.595 1.508 22.666 1.00 6.44 ? 79 LEU A N 1 79 UNP O57413 268 L
ATOM 618 C CA . LEU A 1 79 ? 6.137 1.216 23.991 1.00 7.15 ? 79 LEU A CA 1 79 UNP O57413 268 L
ATOM 619 C C . LEU A 1 79 ? 6.298 2.518 24.785 1.00 6.93 ? 79 LEU A C 1 79 UNP O57413 268 L
ATOM 620 O O . LEU A 1 79 ? 6.049 2.555 25.997 1.00 7.57 ? 79 LEU A O 1 79 UNP O57413 268 L
ATOM 621 C CB . LEU A 1 79 ? 7.496 0.534 23.893 1.00 7.85 ? 79 LEU A CB 1 79 UNP O57413 268 L
ATOM 622 C CG . LEU A 1 79 ? 7.427 -0.874 23.268 1.00 9.11 ? 79 LEU A CG 1 79 UNP O57413 268 L
ATOM 623 C CD1 . LEU A 1 79 ? 8.859 -1.353 23.093 1.00 10.88 ? 79 LEU A CD1 1 79 UNP O57413 268 L
ATOM 624 C CD2 . LEU A 1 79 ? 6.621 -1.860 24.162 1.00 11.35 ? 79 LEU A CD2 1 79 UNP O57413 268 L
ATOM 625 N N . PHE A 1 80 ? 6.704 3.590 24.097 1.00 6.61 ? 80 PHE A N 1 80 UNP O57413 269 F
ATOM 626 C CA . PHE A 1 80 ? 6.874 4.894 24.735 1.00 6.01 ? 80 PHE A CA 1 80 UNP O57413 269 F
ATOM 627 C C . PHE A 1 80 ? 5.523 5.432 25.191 1.00 5.42 ? 80 PHE A C 1 80 UNP O57413 269 F
ATOM 628 O O . PHE A 1 80 ? 5.411 5.960 26.305 1.00 6.26 ? 80 PHE A O 1 80 UNP O57413 269 F
ATOM 629 C CB . PHE A 1 80 ? 7.563 5.858 23.779 1.00 5.97 ? 80 PHE A CB 1 80 UNP O57413 269 F
ATOM 630 C CG . PHE A 1 80 ? 7.810 7.210 24.380 1.00 5.41 ? 80 PHE A CG 1 80 UNP O57413 269 F
ATOM 631 C CD1 . PHE A 1 80 ? 8.617 7.354 25.495 1.00 6.43 ? 80 PHE A CD1 1 80 UNP O57413 269 F
ATOM 632 C CD2 . PHE A 1 80 ? 7.233 8.341 23.821 1.00 4.83 ? 80 PHE A CD2 1 80 UNP O57413 269 F
ATOM 633 C CE1 . PHE A 1 80 ? 8.859 8.633 26.058 1.00 6.42 ? 80 PHE A CE1 1 80 UNP O57413 269 F
ATOM 634 C CE2 . PHE A 1 80 ? 7.472 9.637 24.391 1.00 5.84 ? 80 PHE A CE2 1 80 UNP O57413 269 F
ATOM 635 C CZ . PHE A 1 80 ? 8.281 9.758 25.494 1.00 7.06 ? 80 PHE A CZ 1 80 UNP O57413 269 F
ATOM 636 N N . GLY A 1 81 ? 4.497 5.314 24.355 1.00 5.44 ? 81 GLY A N 1 81 UNP O57413 270 G
ATOM 637 C CA . GLY A 1 81 ? 3.169 5.766 24.753 1.00 7.00 ? 81 GLY A CA 1 81 UNP O57413 270 G
ATOM 638 C C . GLY A 1 81 ? 2.636 5.010 25.964 1.00 7.37 ? 81 GLY A C 1 81 UNP O57413 270 G
ATOM 639 O O . GLY A 1 81 ? 2.005 5.596 26.858 1.00 7.57 ? 81 GLY A O 1 81 UNP O57413 270 G
ATOM 640 N N . ASP A 1 82 ? 2.912 3.715 26.019 1.00 7.26 ? 82 ASP A N 1 82 UNP O57413 271 D
ATOM 641 C CA . ASP A 1 82 ? 2.441 2.905 27.156 1.00 8.27 ? 82 ASP A CA 1 82 UNP O57413 271 D
ATOM 642 C C . ASP A 1 82 ? 3.167 3.396 28.416 1.00 8.39 ? 82 ASP A C 1 82 UNP O57413 271 D
ATOM 643 O O . ASP A 1 82 ? 2.538 3.568 29.477 1.00 8.81 ? 82 ASP A O 1 82 UNP O57413 271 D
ATOM 644 C CB . ASP A 1 82 ? 2.800 1.435 26.937 1.00 10.22 ? 82 ASP A CB 1 82 UNP O57413 271 D
ATOM 645 C CG . ASP A 1 82 ? 1.882 0.745 25.951 1.00 12.84 ? 82 ASP A CG 1 82 UNP O57413 271 D
ATOM 646 O OD1 . ASP A 1 82 ? 2.260 -0.348 25.449 1.00 15.63 ? 82 ASP A OD1 1 82 UNP O57413 271 D
ATOM 647 O OD2 . ASP A 1 82 ? 0.787 1.288 25.693 1.00 14.20 ? 82 ASP A OD2 1 82 UNP O57413 271 D
ATOM 648 N N . TRP A 1 83 ? 4.472 3.618 28.311 1.00 8.02 ? 83 TRP A N 1 83 UNP O57413 272 W
ATOM 649 C CA . TRP A 1 83 ? 5.276 4.056 29.445 1.00 8.66 ? 83 TRP A CA 1 83 UNP O57413 272 W
ATOM 650 C C . TRP A 1 83 ? 4.878 5.484 29.846 1.00 8.43 ? 83 TRP A C 1 83 UNP O57413 272 W
ATOM 651 O O . TRP A 1 83 ? 4.839 5.813 31.041 1.00 9.63 ? 83 TRP A O 1 83 UNP O57413 272 W
ATOM 652 C CB . TRP A 1 83 ? 6.762 3.955 29.102 1.00 8.61 ? 83 TRP A CB 1 83 UNP O57413 272 W
ATOM 653 C CG . TRP A 1 83 ? 7.663 4.412 30.182 1.00 9.24 ? 83 TRP A CG 1 83 UNP O57413 272 W
ATOM 654 C CD1 . TRP A 1 83 ? 8.098 3.695 31.265 1.00 9.36 ? 83 TRP A CD1 1 83 UNP O57413 272 W
ATOM 655 C CD2 . TRP A 1 83 ? 8.201 5.720 30.327 1.00 8.84 ? 83 TRP A CD2 1 83 UNP O57413 272 W
ATOM 656 N NE1 . TRP A 1 83 ? 8.864 4.478 32.068 1.00 10.75 ? 83 TRP A NE1 1 83 UNP O57413 272 W
ATOM 657 C CE2 . TRP A 1 83 ? 8.950 5.734 31.525 1.00 9.73 ? 83 TRP A CE2 1 83 UNP O57413 272 W
ATOM 658 C CE3 . TRP A 1 83 ? 8.122 6.887 29.569 1.00 9.47 ? 83 TRP A CE3 1 83 UNP O57413 272 W
ATOM 659 C CZ2 . TRP A 1 83 ? 9.619 6.888 31.986 1.00 10.02 ? 83 TRP A CZ2 1 83 UNP O57413 272 W
ATOM 660 C CZ3 . TRP A 1 83 ? 8.789 8.032 30.030 1.00 10.43 ? 83 TRP A CZ3 1 83 UNP O57413 272 W
ATOM 661 C CH2 . TRP A 1 83 ? 9.522 8.021 31.224 1.00 9.73 ? 83 TRP A CH2 1 83 UNP O57413 272 W
ATOM 662 N N . ARG A 1 84 ? 4.552 6.328 28.873 1.00 8.18 ? 84 ARG A N 1 84 UNP O57413 273 R
ATOM 663 C CA . ARG A 1 84 ? 4.096 7.679 29.199 1.00 8.20 ? 84 ARG A CA 1 84 UNP O57413 273 R
ATOM 664 C C . ARG A 1 84 ? 2.781 7.623 30.018 1.00 8.48 ? 84 ARG A C 1 84 UNP O57413 273 R
ATOM 665 O O . ARG A 1 84 ? 2.631 8.385 30.994 1.00 8.90 ? 84 ARG A O 1 84 UNP O57413 273 R
ATOM 666 C CB . ARG A 1 84 ? 3.840 8.463 27.914 1.00 8.02 ? 84 ARG A CB 1 84 UNP O57413 273 R
ATOM 667 C CG . ARG A 1 84 ? 3.256 9.818 28.231 1.00 10.01 ? 84 ARG A CG 1 84 UNP O57413 273 R
ATOM 668 C CD . ARG A 1 84 ? 2.640 10.506 27.066 1.00 10.11 ? 84 ARG A CD 1 84 UNP O57413 273 R
ATOM 669 N NE . ARG A 1 84 ? 2.186 11.832 27.474 1.00 9.31 ? 84 ARG A NE 1 84 UNP O57413 273 R
ATOM 670 C CZ . ARG A 1 84 ? 0.967 12.305 27.239 1.00 10.44 ? 84 ARG A CZ 1 84 UNP O57413 273 R
ATOM 671 N NH1 . ARG A 1 84 ? 0.047 11.571 26.620 1.00 9.95 ? 84 ARG A NH1 1 84 UNP O57413 273 R
ATOM 672 N NH2 . ARG A 1 84 ? 0.695 13.548 27.566 1.00 8.09 ? 84 ARG A NH2 1 84 UNP O57413 273 R
ATOM 673 N N . GLU A 1 85 ? 1.841 6.779 29.615 1.00 8.31 ? 85 GLU A N 1 85 UNP O57413 274 E
ATOM 674 C CA . GLU A 1 85 ? 0.573 6.696 30.326 1.00 8.92 ? 85 GLU A CA 1 85 UNP O57413 274 E
ATOM 675 C C . GLU A 1 85 ? 0.752 6.079 31.711 1.00 9.46 ? 85 GLU A C 1 85 UNP O57413 274 E
ATOM 676 O O . GLU A 1 85 ? 0.126 6.543 32.689 1.00 11.07 ? 85 GLU A O 1 85 UNP O57413 274 E
ATOM 677 C CB . GLU A 1 85 ? -0.438 5.850 29.531 1.00 10.26 ? 85 GLU A CB 1 85 UNP O57413 274 E
ATOM 678 C CG . GLU A 1 85 ? -1.864 5.738 30.145 1.00 12.02 ? 85 GLU A CG 1 85 UNP O57413 274 E
ATOM 679 C CD . GLU A 1 85 ? -2.064 4.634 31.222 1.00 14.90 ? 85 GLU A CD 1 85 UNP O57413 274 E
ATOM 680 O OE1 . GLU A 1 85 ? -1.261 3.688 31.345 1.00 13.80 ? 85 GLU A OE1 1 85 UNP O57413 274 E
ATOM 681 O OE2 . GLU A 1 85 ? -3.081 4.732 31.940 1.00 14.86 ? 85 GLU A OE2 1 85 UNP O57413 274 E
ATOM 682 N N . ARG A 1 86 ? 1.642 5.106 31.834 1.00 8.93 ? 86 ARG A N 1 86 UNP O57413 275 R
ATOM 683 C CA . ARG A 1 86 ? 1.810 4.400 33.113 1.00 10.70 ? 86 ARG A CA 1 86 UNP O57413 275 R
ATOM 684 C C . ARG A 1 86 ? 2.714 5.114 34.083 1.00 10.42 ? 86 ARG A C 1 86 UNP O57413 275 R
ATOM 685 O O . ARG A 1 86 ? 2.442 5.159 35.310 1.00 12.78 ? 86 ARG A O 1 86 UNP O57413 275 R
ATOM 686 C CB . ARG A 1 86 ? 2.371 2.996 32.843 1.00 11.20 ? 86 ARG A CB 1 86 UNP O57413 275 R
ATOM 687 C CG . ARG A 1 86 ? 2.579 2.161 34.110 1.00 14.02 ? 86 ARG A CG 1 86 UNP O57413 275 R
ATOM 688 C CD . ARG A 1 86 ? 2.969 0.713 33.784 1.00 15.64 ? 86 ARG A CD 1 86 UNP O57413 275 R
ATOM 689 N NE . ARG A 1 86 ? 4.180 0.622 32.986 1.00 18.82 ? 86 ARG A NE 1 86 UNP O57413 275 R
ATOM 690 C CZ . ARG A 1 86 ? 5.418 0.699 33.466 1.00 19.92 ? 86 ARG A CZ 1 86 UNP O57413 275 R
ATOM 691 N NH1 . ARG A 1 86 ? 5.636 0.869 34.774 1.00 22.62 ? 86 ARG A NH1 1 86 UNP O57413 275 R
ATOM 692 N NH2 . ARG A 1 86 ? 6.448 0.595 32.636 1.00 21.53 ? 86 ARG A NH2 1 86 UNP O57413 275 R
ATOM 693 N N . VAL A 1 87 ? 3.761 5.735 33.563 1.00 10.58 ? 87 VAL A N 1 87 UNP O57413 276 V
ATOM 694 C CA . VAL A 1 87 ? 4.764 6.370 34.396 1.00 10.30 ? 87 VAL A CA 1 87 UNP O57413 276 V
ATOM 695 C C . VAL A 1 87 ? 4.917 7.880 34.245 1.00 11.12 ? 87 VAL A C 1 87 UNP O57413 276 V
ATOM 696 O O . VAL A 1 87 ? 4.727 8.617 35.204 1.00 11.02 ? 87 VAL A O 1 87 UNP O57413 276 V
ATOM 697 C CB . VAL A 1 87 ? 6.161 5.701 34.146 1.00 10.84 ? 87 VAL A CB 1 87 UNP O57413 276 V
ATOM 698 C CG1 . VAL A 1 87 ? 7.266 6.357 34.986 1.00 11.77 ? 87 VAL A CG1 1 87 UNP O57413 276 V
ATOM 699 C CG2 . VAL A 1 87 ? 6.087 4.220 34.452 1.00 11.47 ? 87 VAL A CG2 1 87 UNP O57413 276 V
ATOM 700 N N . LEU A 1 88 ? 5.236 8.347 33.046 1.00 11.26 ? 88 LEU A N 1 88 UNP O57413 277 L
ATOM 701 C CA . LEU A 1 88 ? 5.505 9.779 32.889 1.00 11.00 ? 88 LEU A CA 1 88 UNP O57413 277 L
ATOM 702 C C . LEU A 1 88 ? 4.372 10.729 33.303 1.00 10.08 ? 88 LEU A C 1 88 UNP O57413 277 L
ATOM 703 O O . LEU A 1 88 ? 4.634 11.742 33.950 1.00 11.18 ? 88 LEU A O 1 88 UNP O57413 277 L
ATOM 704 C CB . LEU A 1 88 ? 5.952 10.068 31.454 1.00 12.05 ? 88 LEU A CB 1 88 UNP O57413 277 L
ATOM 705 C CG . LEU A 1 88 ? 6.680 11.397 31.238 1.00 12.59 ? 88 LEU A CG 1 88 UNP O57413 277 L
ATOM 706 C CD1 . LEU A 1 88 ? 8.024 11.420 31.971 1.00 14.80 ? 88 LEU A CD1 1 88 UNP O57413 277 L
ATOM 707 C CD2 . LEU A 1 88 ? 6.864 11.578 29.739 1.00 12.50 ? 88 LEU A CD2 1 88 UNP O57413 277 L
ATOM 708 N N . LEU A 1 89 ? 3.134 10.421 32.927 1.00 9.74 ? 89 LEU A N 1 89 UNP O57413 278 L
ATOM 709 C CA . LEU A 1 89 ? 1.995 11.259 33.293 1.00 9.62 ? 89 LEU A CA 1 89 UNP O57413 278 L
ATOM 710 C C . LEU A 1 89 ? 1.742 11.284 34.790 1.00 11.30 ? 89 LEU A C 1 89 UNP O57413 278 L
ATOM 711 O O . LEU A 1 89 ? 1.113 12.219 35.284 1.00 11.31 ? 89 LEU A O 1 89 UNP O57413 278 L
ATOM 712 C CB . LEU A 1 89 ? 0.730 10.822 32.567 1.00 9.28 ? 89 LEU A CB 1 89 UNP O57413 278 L
ATOM 713 C CG . LEU A 1 89 ? 0.647 11.399 31.143 1.00 9.70 ? 89 LEU A CG 1 89 UNP O57413 278 L
ATOM 714 C CD1 . LEU A 1 89 ? -0.443 10.702 30.351 1.00 10.87 ? 89 LEU A CD1 1 89 UNP O57413 278 L
ATOM 715 C CD2 . LEU A 1 89 ? 0.339 12.898 31.231 1.00 10.39 ? 89 LEU A CD2 1 89 UNP O57413 278 L
ATOM 716 N N . LYS A 1 90 ? 2.217 10.270 35.508 1.00 11.37 ? 90 LYS A N 1 90 UNP O57413 279 K
ATOM 717 C CA . LYS A 1 90 ? 2.058 10.236 36.973 1.00 13.15 ? 90 LYS A CA 1 90 UNP O57413 279 K
ATOM 718 C C . LYS A 1 90 ? 3.111 11.131 37.632 1.00 13.66 ? 90 LYS A C 1 90 UNP O57413 279 K
ATOM 719 O O . LYS A 1 90 ? 2.949 11.534 38.788 1.00 15.12 ? 90 LYS A O 1 90 UNP O57413 279 K
ATOM 720 C CB . LYS A 1 90 ? 2.176 8.797 37.486 1.00 14.29 ? 90 LYS A CB 1 90 UNP O57413 279 K
ATOM 721 C CG . LYS A 1 90 ? 1.074 7.849 37.007 1.00 17.85 ? 90 LYS A CG 1 90 UNP O57413 279 K
ATOM 722 C CD . LYS A 1 90 ? -0.314 8.361 37.321 1.00 21.94 ? 90 LYS A CD 1 90 UNP O57413 279 K
ATOM 723 C CE . LYS A 1 90 ? -1.401 7.358 36.869 1.00 23.36 ? 90 LYS A CE 1 90 UNP O57413 279 K
ATOM 724 N NZ . LYS A 1 90 ? -1.394 7.083 35.406 1.00 24.84 ? 90 LYS A NZ 1 90 UNP O57413 279 K
ATOM 725 N N . LYS A 1 91 ? 4.172 11.465 36.912 1.00 12.75 ? 91 LYS A N 1 91 UNP O57413 280 K
ATOM 726 C CA . LYS A 1 91 ? 5.221 12.327 37.448 1.00 13.90 ? 91 LYS A CA 1 91 UNP O57413 280 K
ATOM 727 C C . LYS A 1 91 ? 4.783 13.785 37.372 1.00 13.00 ? 91 LYS A C 1 91 UNP O57413 280 K
ATOM 728 O O . LYS A 1 91 ? 4.929 14.530 38.338 1.00 14.35 ? 91 LYS A O 1 91 UNP O57413 280 K
ATOM 729 C CB . LYS A 1 91 ? 6.518 12.172 36.662 1.00 15.39 ? 91 LYS A CB 1 91 UNP O57413 280 K
ATOM 730 C CG . LYS A 1 91 ? 7.087 10.768 36.663 1.00 19.11 ? 91 LYS A CG 1 91 UNP O57413 280 K
ATOM 731 C CD . LYS A 1 91 ? 8.586 10.775 36.614 1.00 21.61 ? 91 LYS A CD 1 91 UNP O57413 280 K
ATOM 732 C CE . LYS A 1 91 ? 9.108 11.582 35.439 1.00 22.00 ? 91 LYS A CE 1 91 UNP O57413 280 K
ATOM 733 N NZ . LYS A 1 91 ? 10.589 11.570 35.387 1.00 23.46 ? 91 LYS A NZ 1 91 UNP O57413 280 K
ATOM 734 N N . LYS A 1 92 ? 4.267 14.201 36.219 1.00 11.96 ? 92 LYS A N 1 92 UNP O57413 281 K
ATOM 735 C CA . LYS A 1 92 ? 3.797 15.568 36.040 1.00 11.48 ? 92 LYS A CA 1 92 UNP O57413 281 K
ATOM 736 C C . LYS A 1 92 ? 2.873 15.597 34.846 1.00 10.78 ? 92 LYS A C 1 92 UNP O57413 281 K
ATOM 737 O O . LYS A 1 92 ? 3.190 15.002 33.795 1.00 10.47 ? 92 LYS A O 1 92 UNP O57413 281 K
ATOM 738 C CB . LYS A 1 92 ? 4.976 16.525 35.808 1.00 11.09 ? 92 LYS A CB 1 92 UNP O57413 281 K
ATOM 739 C CG . LYS A 1 92 ? 4.568 17.990 35.871 1.00 11.51 ? 92 LYS A CG 1 92 UNP O57413 281 K
ATOM 740 C CD . LYS A 1 92 ? 5.791 18.922 35.715 1.00 12.25 ? 92 LYS A CD 1 92 UNP O57413 281 K
ATOM 741 C CE . LYS A 1 92 ? 5.388 20.414 35.767 1.00 12.10 ? 92 LYS A CE 1 92 UNP O57413 281 K
ATOM 742 N NZ . LYS A 1 92 ? 6.541 21.281 35.491 1.00 12.84 ? 92 LYS A NZ 1 92 UNP O57413 281 K
ATOM 743 N N . ASN A 1 93 ? 1.738 16.280 34.970 1.00 10.50 ? 93 ASN A N 1 93 UNP O57413 282 N
ATOM 744 C CA . ASN A 1 93 ? 0.821 16.325 33.852 1.00 11.78 ? 93 ASN A CA 1 93 UNP O57413 282 N
ATOM 745 C C . ASN A 1 93 ? 1.388 17.155 32.726 1.00 10.24 ? 93 ASN A C 1 93 UNP O57413 282 N
ATOM 746 O O . ASN A 1 93 ? 2.113 18.110 32.940 1.00 10.76 ? 93 ASN A O 1 93 UNP O57413 282 N
ATOM 747 C CB . ASN A 1 93 ? -0.523 16.892 34.242 1.00 15.53 ? 93 ASN A CB 1 93 UNP O57413 282 N
ATOM 748 C CG . ASN A 1 93 ? -1.521 16.772 33.114 1.00 18.08 ? 93 ASN A CG 1 93 UNP O57413 282 N
ATOM 749 O OD1 . ASN A 1 93 ? -1.673 15.695 32.506 1.00 19.61 ? 93 ASN A OD1 1 93 UNP O57413 282 N
ATOM 750 N ND2 . ASN A 1 93 ? -2.195 17.871 32.804 1.00 20.97 ? 93 ASN A ND2 1 93 UNP O57413 282 N
ATOM 751 N N . HIS A 1 94 ? 1.101 16.712 31.514 1.00 9.17 ? 94 HIS A N 1 94 UNP O57413 283 H
ATOM 752 C CA . HIS A 1 94 ? 1.547 17.403 30.312 1.00 7.43 ? 94 HIS A CA 1 94 UNP O57413 283 H
ATOM 753 C C . HIS A 1 94 ? 0.656 16.909 29.162 1.00 7.10 ? 94 HIS A C 1 94 UNP O57413 283 H
ATOM 754 O O . HIS A 1 94 ? -0.106 15.931 29.298 1.00 6.78 ? 94 HIS A O 1 94 UNP O57413 283 H
ATOM 755 C CB . HIS A 1 94 ? 3.022 17.124 30.041 1.00 7.83 ? 94 HIS A CB 1 94 UNP O57413 283 H
ATOM 756 C CG . HIS A 1 94 ? 3.332 15.670 29.890 1.00 6.72 ? 94 HIS A CG 1 94 UNP O57413 283 H
ATOM 757 N ND1 . HIS A 1 94 ? 3.477 14.819 30.970 1.00 7.99 ? 94 HIS A ND1 1 94 UNP O57413 283 H
ATOM 758 C CD2 . HIS A 1 94 ? 3.493 14.911 28.782 1.00 6.38 ? 94 HIS A CD2 1 94 UNP O57413 283 H
ATOM 759 C CE1 . HIS A 1 94 ? 3.715 13.596 30.524 1.00 8.13 ? 94 HIS A CE1 1 94 UNP O57413 283 H
ATOM 760 N NE2 . HIS A 1 94 ? 3.735 13.625 29.202 1.00 7.36 ? 94 HIS A NE2 1 94 UNP O57413 283 H
ATOM 761 N N . ASP A 1 95 ? 0.772 17.571 28.023 1.00 6.07 ? 95 ASP A N 1 95 UNP O57413 284 D
ATOM 762 C CA . ASP A 1 95 ? -0.096 17.291 26.894 1.00 5.97 ? 95 ASP A CA 1 95 UNP O57413 284 D
ATOM 763 C C . ASP A 1 95 ? 0.390 16.367 25.805 1.00 5.59 ? 95 ASP A C 1 95 UNP O57413 284 D
ATOM 764 O O . ASP A 1 95 ? -0.424 15.739 25.127 1.00 6.03 ? 95 ASP A O 1 95 UNP O57413 284 D
ATOM 765 C CB . ASP A 1 95 ? -0.475 18.609 26.196 1.00 7.08 ? 95 ASP A CB 1 95 UNP O57413 284 D
ATOM 766 C CG . ASP A 1 95 ? -1.132 19.598 27.124 1.00 9.14 ? 95 ASP A CG 1 95 UNP O57413 284 D
ATOM 767 O OD1 . ASP A 1 95 ? -0.832 20.807 26.975 1.00 9.37 ? 95 ASP A OD1 1 95 UNP O57413 284 D
ATOM 768 O OD2 . ASP A 1 95 ? -1.933 19.173 27.982 1.00 10.52 ? 95 ASP A OD2 1 95 UNP O57413 284 D
ATOM 769 N N . HIS A 1 96 ? 1.696 16.340 25.613 1.00 4.75 ? 96 HIS A N 1 96 UNP O57413 285 H
ATOM 770 C CA . HIS A 1 96 ? 2.304 15.577 24.523 1.00 4.90 ? 96 HIS A CA 1 96 UNP O57413 285 H
ATOM 771 C C . HIS A 1 96 ? 3.714 15.300 24.953 1.00 4.47 ? 96 HIS A C 1 96 UNP O57413 285 H
ATOM 772 O O . HIS A 1 96 ? 4.360 16.160 25.572 1.00 5.06 ? 96 HIS A O 1 96 UNP O57413 285 H
ATOM 773 C CB . HIS A 1 96 ? 2.319 16.460 23.253 1.00 4.75 ? 96 HIS A CB 1 96 UNP O57413 285 H
ATOM 774 C CG . HIS A 1 96 ? 2.885 15.791 22.029 1.00 4.42 ? 96 HIS A CG 1 96 UNP O57413 285 H
ATOM 775 N ND1 . HIS A 1 96 ? 4.162 15.990 21.530 1.00 7.95 ? 96 HIS A ND1 1 96 UNP O57413 285 H
ATOM 776 C CD2 . HIS A 1 96 ? 2.279 14.942 21.173 1.00 3.16 ? 96 HIS A CD2 1 96 UNP O57413 285 H
ATOM 777 C CE1 . HIS A 1 96 ? 4.312 15.285 20.412 1.00 3.51 ? 96 HIS A CE1 1 96 UNP O57413 285 H
ATOM 778 N NE2 . HIS A 1 96 ? 3.181 14.640 20.182 1.00 6.54 ? 96 HIS A NE2 1 96 UNP O57413 285 H
ATOM 779 N N . ALA A 1 97 ? 4.226 14.118 24.645 1.00 5.21 ? 97 ALA A N 1 97 UNP O57413 286 A
ATOM 780 C CA . ALA A 1 97 ? 5.605 13.787 24.985 1.00 4.76 ? 97 ALA A CA 1 97 UNP O57413 286 A
ATOM 781 C C . ALA A 1 97 ? 6.375 13.279 23.767 1.00 4.50 ? 97 ALA A C 1 97 UNP O57413 286 A
ATOM 782 O O . ALA A 1 97 ? 5.834 12.518 22.952 1.00 5.10 ? 97 ALA A O 1 97 UNP O57413 286 A
ATOM 783 C CB . ALA A 1 97 ? 5.635 12.679 26.034 1.00 6.06 ? 97 ALA A CB 1 97 UNP O57413 286 A
ATOM 784 N N . GLN A 1 98 ? 7.634 13.702 23.651 1.00 4.56 ? 98 GLN A N 1 98 UNP O57413 287 Q
ATOM 785 C CA . GLN A 1 98 ? 8.477 13.173 22.572 1.00 4.20 ? 98 GLN A CA 1 98 UNP O57413 287 Q
ATOM 786 C C . GLN A 1 98 ? 9.716 12.518 23.143 1.00 5.02 ? 98 GLN A C 1 98 UNP O57413 287 Q
ATOM 787 O O . GLN A 1 98 ? 10.324 13.035 24.096 1.00 5.03 ? 98 GLN A O 1 98 UNP O57413 287 Q
ATOM 788 C CB . GLN A 1 98 ? 8.891 14.273 21.607 1.00 4.38 ? 98 GLN A CB 1 98 UNP O57413 287 Q
ATOM 789 C CG . GLN A 1 98 ? 7.688 14.981 21.010 1.00 4.60 ? 98 GLN A CG 1 98 UNP O57413 287 Q
ATOM 790 C CD . GLN A 1 98 ? 8.011 15.699 19.724 1.00 4.66 ? 98 GLN A CD 1 98 UNP O57413 287 Q
ATOM 791 O OE1 . GLN A 1 98 ? 9.186 15.940 19.371 1.00 6.85 ? 98 GLN A OE1 1 98 UNP O57413 287 Q
ATOM 792 N NE2 . GLN A 1 98 ? 6.954 16.062 18.996 1.00 4.91 ? 98 GLN A NE2 1 98 UNP O57413 287 Q
ATOM 793 N N . LEU A 1 99 ? 10.079 11.376 22.568 1.00 4.95 ? 99 LEU A N 1 99 UNP O57413 288 L
ATOM 794 C CA . LEU A 1 99 ? 11.281 10.657 22.944 1.00 5.46 ? 99 LEU A CA 1 99 UNP O57413 288 L
ATOM 795 C C . LEU A 1 99 ? 12.365 11.035 21.953 1.00 5.35 ? 99 LEU A C 1 99 UNP O57413 288 L
ATOM 796 O O . LEU A 1 99 ? 12.180 10.824 20.755 1.00 5.93 ? 99 LEU A O 1 99 UNP O57413 288 L
ATOM 797 C CB . LEU A 1 99 ? 11.017 9.137 22.861 1.00 6.20 ? 99 LEU A CB 1 99 UNP O57413 288 L
ATOM 798 C CG . LEU A 1 99 ? 12.249 8.270 23.140 1.00 6.93 ? 99 LEU A CG 1 99 UNP O57413 288 L
ATOM 799 C CD1 . LEU A 1 99 ? 12.674 8.370 24.613 1.00 9.02 ? 99 LEU A CD1 1 99 UNP O57413 288 L
ATOM 800 C CD2 . LEU A 1 99 ? 11.888 6.832 22.757 1.00 9.39 ? 99 LEU A CD2 1 99 UNP O57413 288 L
ATOM 801 N N . LEU A 1 100 ? 13.477 11.555 22.433 1.00 5.39 ? 100 LEU A N 1 100 UNP O57413 289 L
ATOM 802 C CA . LEU A 1 100 ? 14.622 11.895 21.592 1.00 5.26 ? 100 LEU A CA 1 100 UNP O57413 289 L
ATOM 803 C C . LEU A 1 100 ? 15.635 10.761 21.781 1.00 5.70 ? 100 LEU A C 1 100 UNP O57413 289 L
ATOM 804 O O . LEU A 1 100 ? 15.984 10.415 22.903 1.00 7.60 ? 100 LEU A O 1 100 UNP O57413 289 L
ATOM 805 C CB . LEU A 1 100 ? 15.247 13.227 22.032 1.00 7.81 ? 100 LEU A CB 1 100 UNP O57413 289 L
ATOM 806 C CG . LEU A 1 100 ? 14.515 14.493 21.629 1.00 9.21 ? 100 LEU A CG 1 100 UNP O57413 289 L
ATOM 807 C CD1 . LEU A 1 100 ? 15.243 15.671 22.271 1.00 11.71 ? 100 LEU A CD1 1 100 UNP O57413 289 L
ATOM 808 C CD2 . LEU A 1 100 ? 14.554 14.678 20.112 1.00 12.75 ? 100 LEU A CD2 1 100 UNP O57413 289 L
ATOM 809 N N . THR A 1 101 ? 16.158 10.251 20.664 1.00 6.25 ? 101 THR A N 1 101 UNP O57413 290 T
ATOM 810 C CA . THR A 1 101 ? 17.072 9.117 20.715 1.00 6.21 ? 101 THR A CA 1 101 UNP O57413 290 T
ATOM 811 C C . THR A 1 101 ? 18.114 9.218 19.625 1.00 6.26 ? 101 THR A C 1 101 UNP O57413 290 T
ATOM 812 O O . THR A 1 101 ? 17.910 9.929 18.636 1.00 6.74 ? 101 THR A O 1 101 UNP O57413 290 T
ATOM 813 C CB . THR A 1 101 ? 16.241 7.807 20.512 1.00 6.89 ? 101 THR A CB 1 101 UNP O57413 290 T
ATOM 814 O OG1 . THR A 1 101 ? 17.098 6.660 20.605 1.00 8.81 ? 101 THR A OG1 1 101 UNP O57413 290 T
ATOM 815 C CG2 . THR A 1 101 ? 15.593 7.778 19.150 1.00 8.07 ? 101 THR A CG2 1 101 UNP O57413 290 T
ATOM 816 N N . ASP A 1 102 ? 19.242 8.521 19.783 1.00 6.08 ? 102 ASP A N 1 102 UNP O57413 291 D
ATOM 817 C CA . ASP A 1 102 ? 20.208 8.486 18.710 1.00 7.00 ? 102 ASP A CA 1 102 UNP O57413 291 D
ATOM 818 C C . ASP A 1 102 ? 20.080 7.189 17.887 1.00 6.28 ? 102 ASP A C 1 102 UNP O57413 291 D
ATOM 819 O O . ASP A 1 102 ? 20.900 6.897 17.023 1.00 8.05 ? 102 ASP A O 1 102 UNP O57413 291 D
ATOM 820 C CB . ASP A 1 102 ? 21.611 8.598 19.270 1.00 8.76 ? 102 ASP A CB 1 102 UNP O57413 291 D
ATOM 821 C CG . ASP A 1 102 ? 22.603 8.873 18.211 1.00 10.99 ? 102 ASP A CG 1 102 UNP O57413 291 D
ATOM 822 O OD1 . ASP A 1 102 ? 23.625 8.172 18.208 1.00 14.59 ? 102 ASP A OD1 1 102 UNP O57413 291 D
ATOM 823 O OD2 . ASP A 1 102 ? 22.375 9.790 17.385 1.00 14.73 ? 102 ASP A OD2 1 102 UNP O57413 291 D
ATOM 824 N N . THR A 1 103 ? 19.050 6.406 18.186 1.00 6.09 ? 103 THR A N 1 103 UNP O57413 292 T
ATOM 825 C CA . THR A 1 103 ? 18.815 5.127 17.503 1.00 6.20 ? 103 THR A CA 1 103 UNP O57413 292 T
ATOM 826 C C . THR A 1 103 ? 18.736 5.271 16.010 1.00 6.68 ? 103 THR A C 1 103 UNP O57413 292 T
ATOM 827 O O . THR A 1 103 ? 18.073 6.151 15.496 1.00 6.47 ? 103 THR A O 1 103 UNP O57413 292 T
ATOM 828 C CB . THR A 1 103 ? 17.491 4.493 18.011 1.00 5.69 ? 103 THR A CB 1 103 UNP O57413 292 T
ATOM 829 O OG1 . THR A 1 103 ? 17.613 4.238 19.415 1.00 7.61 ? 103 THR A OG1 1 103 UNP O57413 292 T
ATOM 830 C CG2 . THR A 1 103 ? 17.163 3.201 17.273 1.00 6.66 ? 103 THR A CG2 1 103 UNP O57413 292 T
ATOM 831 N N . ASN A 1 104 ? 19.438 4.389 15.293 1.00 6.29 ? 104 ASN A N 1 104 UNP O57413 293 N
ATOM 832 C CA . ASN A 1 104 ? 19.379 4.392 13.837 1.00 7.96 ? 104 ASN A CA 1 104 UNP O57413 293 N
ATOM 833 C C . ASN A 1 104 ? 18.094 3.615 13.464 1.00 7.69 ? 104 ASN A C 1 104 UNP O57413 293 N
ATOM 834 O O . ASN A 1 104 ? 18.131 2.403 13.178 1.00 8.06 ? 104 ASN A O 1 104 UNP O57413 293 N
ATOM 835 C CB . ASN A 1 104 ? 20.652 3.692 13.288 1.00 9.12 ? 104 ASN A CB 1 104 UNP O57413 293 N
ATOM 836 C CG . ASN A 1 104 ? 20.825 3.871 11.817 1.00 11.14 ? 104 ASN A CG 1 104 UNP O57413 293 N
ATOM 837 O OD1 . ASN A 1 104 ? 21.771 3.343 11.222 1.00 15.08 ? 104 ASN A OD1 1 104 UNP O57413 293 N
ATOM 838 N ND2 . ASN A 1 104 ? 19.952 4.610 11.219 1.00 11.04 ? 104 ASN A ND2 1 104 UNP O57413 293 N
ATOM 839 N N . PHE A 1 105 ? 16.952 4.293 13.483 1.00 6.32 ? 105 PHE A N 1 105 UNP O57413 294 F
ATOM 840 C CA . PHE A 1 105 ? 15.688 3.654 13.165 1.00 6.26 ? 105 PHE A CA 1 105 UNP O57413 294 F
ATOM 841 C C . PHE A 1 105 ? 15.683 3.072 11.770 1.00 6.61 ? 105 PHE A C 1 105 UNP O57413 294 F
ATOM 842 O O . PHE A 1 105 ? 16.304 3.607 10.837 1.00 7.32 ? 105 PHE A O 1 105 UNP O57413 294 F
ATOM 843 C CB . PHE A 1 105 ? 14.504 4.625 13.266 1.00 7.18 ? 105 PHE A CB 1 105 UNP O57413 294 F
ATOM 844 C CG . PHE A 1 105 ? 14.177 5.093 14.658 1.00 7.11 ? 105 PHE A CG 1 105 UNP O57413 294 F
ATOM 845 C CD1 . PHE A 1 105 ? 14.049 6.460 14.901 1.00 8.81 ? 105 PHE A CD1 1 105 UNP O57413 294 F
ATOM 846 C CD2 . PHE A 1 105 ? 13.873 4.197 15.684 1.00 7.63 ? 105 PHE A CD2 1 105 UNP O57413 294 F
ATOM 847 C CE1 . PHE A 1 105 ? 13.604 6.940 16.150 1.00 9.72 ? 105 PHE A CE1 1 105 UNP O57413 294 F
ATOM 848 C CE2 . PHE A 1 105 ? 13.431 4.691 16.923 1.00 7.19 ? 105 PHE A CE2 1 105 UNP O57413 294 F
ATOM 849 C CZ . PHE A 1 105 ? 13.296 6.059 17.147 1.00 8.81 ? 105 PHE A CZ 1 105 UNP O57413 294 F
ATOM 850 N N . ALA A 1 106 ? 14.940 1.982 11.646 1.00 6.72 ? 106 ALA A N 1 106 UNP O57413 295 A
ATOM 851 C CA . ALA A 1 106 ? 14.779 1.250 10.403 1.00 7.99 ? 106 ALA A CA 1 106 UNP O57413 295 A
ATOM 852 C C . ALA A 1 106 ? 14.155 2.144 9.339 1.00 8.71 ? 106 ALA A C 1 106 UNP O57413 295 A
ATOM 853 O O . ALA A 1 106 ? 13.449 3.116 9.643 1.00 8.01 ? 106 ALA A O 1 106 UNP O57413 295 A
ATOM 854 C CB . ALA A 1 106 ? 13.873 0.060 10.661 1.00 8.24 ? 106 ALA A CB 1 106 UNP O57413 295 A
ATOM 855 N N . ARG A 1 107 ? 14.338 1.749 8.082 1.00 9.18 ? 107 ARG A N 1 107 UNP O57413 296 R
ATOM 856 C CA . ARG A 1 107 ? 13.805 2.479 6.923 1.00 9.88 ? 107 ARG A CA 1 107 UNP O57413 296 R
ATOM 857 C C . ARG A 1 107 ? 14.258 3.935 6.848 1.00 9.28 ? 107 ARG A C 1 107 UNP O57413 296 R
ATOM 858 O O . ARG A 1 107 ? 13.508 4.807 6.392 1.00 9.58 ? 107 ARG A O 1 107 UNP O57413 296 R
ATOM 859 C CB . ARG A 1 107 ? 12.278 2.339 6.881 1.00 11.83 ? 107 ARG A CB 1 107 UNP O57413 296 R
ATOM 860 C CG . ARG A 1 107 ? 11.845 0.894 6.865 1.00 14.83 ? 107 ARG A CG 1 107 UNP O57413 296 R
ATOM 861 C CD . ARG A 1 107 ? 10.378 0.734 6.507 1.00 18.21 ? 107 ARG A CD 1 107 UNP O57413 296 R
ATOM 862 N NE . ARG A 1 107 ? 10.007 1.529 5.338 1.00 22.71 ? 107 ARG A NE 1 107 UNP O57413 296 R
ATOM 863 C CZ . ARG A 1 107 ? 8.752 1.751 4.943 1.00 24.11 ? 107 ARG A CZ 1 107 UNP O57413 296 R
ATOM 864 N NH1 . ARG A 1 107 ? 7.734 1.232 5.623 1.00 25.83 ? 107 ARG A NH1 1 107 UNP O57413 296 R
ATOM 865 N NH2 . ARG A 1 107 ? 8.512 2.511 3.874 1.00 25.96 ? 107 ARG A NH2 1 107 UNP O57413 296 R
ATOM 866 N N . ASN A 1 108 ? 15.473 4.213 7.304 1.00 8.19 ? 108 ASN A N 1 108 UNP O57413 297 N
ATOM 867 C CA . ASN A 1 108 ? 16.043 5.556 7.235 1.00 8.85 ? 108 ASN A CA 1 108 UNP O57413 297 N
ATOM 868 C C . ASN A 1 108 ? 15.036 6.532 7.876 1.00 8.19 ? 108 ASN A C 1 108 UNP O57413 297 N
ATOM 869 O O . ASN A 1 108 ? 14.778 7.631 7.345 1.00 9.07 ? 108 ASN A O 1 108 UNP O57413 297 N
ATOM 870 C CB . ASN A 1 108 ? 16.277 5.911 5.745 1.00 10.64 ? 108 ASN A CB 1 108 UNP O57413 297 N
ATOM 871 C CG . ASN A 1 108 ? 17.249 7.032 5.548 1.00 12.49 ? 108 ASN A CG 1 108 UNP O57413 297 N
ATOM 872 O OD1 . ASN A 1 108 ? 17.227 7.687 4.491 1.00 15.71 ? 108 ASN A OD1 1 108 UNP O57413 297 N
ATOM 873 N ND2 . ASN A 1 108 ? 18.128 7.260 6.515 1.00 13.95 ? 108 ASN A ND2 1 108 UNP O57413 297 N
ATOM 874 N N . THR A 1 109 ? 14.485 6.153 9.028 1.00 6.48 ? 109 THR A N 1 109 UNP O57413 298 T
ATOM 875 C CA . THR A 1 109 ? 13.453 6.976 9.679 1.00 6.37 ? 109 THR A CA 1 109 UNP O57413 298 T
ATOM 876 C C . THR A 1 109 ? 14.044 7.932 10.694 1.00 6.30 ? 109 THR A C 1 109 UNP O57413 298 T
ATOM 877 O O . THR A 1 109 ? 14.878 7.554 11.509 1.00 6.74 ? 109 THR A O 1 109 UNP O57413 298 T
ATOM 878 C CB . THR A 1 109 ? 12.446 6.063 10.384 1.00 5.17 ? 109 THR A CB 1 109 UNP O57413 298 T
ATOM 879 O OG1 . THR A 1 109 ? 11.758 5.296 9.386 1.00 6.94 ? 109 THR A OG1 1 109 UNP O57413 298 T
ATOM 880 C CG2 . THR A 1 109 ? 11.397 6.853 11.189 1.00 6.88 ? 109 THR A CG2 1 109 UNP O57413 298 T
ATOM 881 N N . ILE A 1 110 ? 13.630 9.196 10.627 1.00 5.33 ? 110 ILE A N 1 110 UNP O57413 299 I
ATOM 882 C CA . ILE A 1 110 ? 14.120 10.200 11.558 1.00 4.77 ? 110 ILE A CA 1 110 UNP O57413 299 I
ATOM 883 C C . ILE A 1 110 ? 13.067 10.681 12.562 1.00 4.73 ? 110 ILE A C 1 110 UNP O57413 299 I
ATOM 884 O O . ILE A 1 110 ? 13.391 11.420 13.505 1.00 4.37 ? 110 ILE A O 1 110 UNP O57413 299 I
ATOM 885 C CB . ILE A 1 110 ? 14.737 11.406 10.810 1.00 5.64 ? 110 ILE A CB 1 110 UNP O57413 299 I
ATOM 886 C CG1 . ILE A 1 110 ? 13.698 12.028 9.869 1.00 5.50 ? 110 ILE A CG1 1 110 UNP O57413 299 I
ATOM 887 C CG2 . ILE A 1 110 ? 16.004 10.935 10.074 1.00 7.18 ? 110 ILE A CG2 1 110 UNP O57413 299 I
ATOM 888 C CD1 . ILE A 1 110 ? 14.148 13.412 9.264 1.00 7.25 ? 110 ILE A CD1 1 110 UNP O57413 299 I
ATOM 889 N N . GLY A 1 111 ? 11.812 10.271 12.349 1.00 4.28 ? 111 GLY A N 1 111 UNP O57413 300 G
ATOM 890 C CA . GLY A 1 111 ? 10.750 10.620 13.275 1.00 4.58 ? 111 GLY A CA 1 111 UNP O57413 300 G
ATOM 891 C C . GLY A 1 111 ? 9.456 9.911 12.936 1.00 4.73 ? 111 GLY A C 1 111 UNP O57413 300 G
ATOM 892 O O . GLY A 1 111 ? 9.267 9.495 11.785 1.00 4.91 ? 111 GLY A O 1 111 UNP O57413 300 G
ATOM 893 N N . TRP A 1 112 ? 8.586 9.740 13.931 1.00 4.02 ? 112 TRP A N 1 112 UNP O57413 301 W
ATOM 894 C CA . TRP A 1 112 ? 7.285 9.103 13.718 1.00 4.47 ? 112 TRP A CA 1 112 UNP O57413 301 W
ATOM 895 C C . TRP A 1 112 ? 6.324 9.519 14.825 1.00 4.82 ? 112 TRP A C 1 112 UNP O57413 301 W
ATOM 896 O O . TRP A 1 112 ? 6.736 9.735 15.973 1.00 5.88 ? 112 TRP A O 1 112 UNP O57413 301 W
ATOM 897 C CB . TRP A 1 112 ? 7.454 7.573 13.731 1.00 5.77 ? 112 TRP A CB 1 112 UNP O57413 301 W
ATOM 898 C CG . TRP A 1 112 ? 6.241 6.825 13.225 1.00 6.59 ? 112 TRP A CG 1 112 UNP O57413 301 W
ATOM 899 C CD1 . TRP A 1 112 ? 5.978 6.477 11.924 1.00 8.76 ? 112 TRP A CD1 1 112 UNP O57413 301 W
ATOM 900 C CD2 . TRP A 1 112 ? 5.134 6.379 13.995 1.00 7.88 ? 112 TRP A CD2 1 112 UNP O57413 301 W
ATOM 901 N NE1 . TRP A 1 112 ? 4.761 5.835 11.846 1.00 10.62 ? 112 TRP A NE1 1 112 UNP O57413 301 W
ATOM 902 C CE2 . TRP A 1 112 ? 4.226 5.763 13.106 1.00 9.29 ? 112 TRP A CE2 1 112 UNP O57413 301 W
ATOM 903 C CE3 . TRP A 1 112 ? 4.813 6.441 15.355 1.00 8.09 ? 112 TRP A CE3 1 112 UNP O57413 301 W
ATOM 904 C CZ2 . TRP A 1 112 ? 3.014 5.206 13.532 1.00 10.30 ? 112 TRP A CZ2 1 112 UNP O57413 301 W
ATOM 905 C CZ3 . TRP A 1 112 ? 3.605 5.891 15.779 1.00 8.56 ? 112 TRP A CZ3 1 112 UNP O57413 301 W
ATOM 906 C CH2 . TRP A 1 112 ? 2.725 5.283 14.871 1.00 10.00 ? 112 TRP A CH2 1 112 UNP O57413 301 W
ATOM 907 N N . ALA A 1 113 ? 5.042 9.641 14.496 1.00 4.46 ? 113 ALA A N 1 113 UNP O57413 302 A
ATOM 908 C CA . ALA A 1 113 ? 4.065 9.981 15.511 1.00 5.42 ? 113 ALA A CA 1 113 UNP O57413 302 A
ATOM 909 C C . ALA A 1 113 ? 2.697 9.473 15.061 1.00 5.71 ? 113 ALA A C 1 113 UNP O57413 302 A
ATOM 910 O O . ALA A 1 113 ? 2.485 9.161 13.903 1.00 7.58 ? 113 ALA A O 1 113 UNP O57413 302 A
ATOM 911 C CB . ALA A 1 113 ? 3.996 11.516 15.678 1.00 6.47 ? 113 ALA A CB 1 113 UNP O57413 302 A
ATOM 912 N N . TYR A 1 114 ? 1.775 9.412 16.013 1.00 5.58 ? 114 TYR A N 1 114 UNP O57413 303 Y
ATOM 913 C CA . TYR A 1 114 ? 0.379 9.045 15.703 1.00 5.96 ? 114 TYR A CA 1 114 UNP O57413 303 Y
ATOM 914 C C . TYR A 1 114 ? -0.293 10.301 15.142 1.00 7.10 ? 114 TYR A C 1 114 UNP O57413 303 Y
ATOM 915 O O . TYR A 1 114 ? -0.028 11.421 15.582 1.00 7.19 ? 114 TYR A O 1 114 UNP O57413 303 Y
ATOM 916 C CB . TYR A 1 114 ? -0.345 8.632 16.979 1.00 6.19 ? 114 TYR A CB 1 114 UNP O57413 303 Y
ATOM 917 C CG . TYR A 1 114 ? 0.219 7.394 17.600 1.00 6.37 ? 114 TYR A CG 1 114 UNP O57413 303 Y
ATOM 918 C CD1 . TYR A 1 114 ? -0.124 6.126 17.107 1.00 7.94 ? 114 TYR A CD1 1 114 UNP O57413 303 Y
ATOM 919 C CD2 . TYR A 1 114 ? 1.129 7.473 18.653 1.00 6.81 ? 114 TYR A CD2 1 114 UNP O57413 303 Y
ATOM 920 C CE1 . TYR A 1 114 ? 0.447 4.959 17.662 1.00 8.67 ? 114 TYR A CE1 1 114 UNP O57413 303 Y
ATOM 921 C CE2 . TYR A 1 114 ? 1.692 6.318 19.224 1.00 7.13 ? 114 TYR A CE2 1 114 UNP O57413 303 Y
ATOM 922 C CZ . TYR A 1 114 ? 1.334 5.071 18.708 1.00 8.45 ? 114 TYR A CZ 1 114 UNP O57413 303 Y
ATOM 923 O OH . TYR A 1 114 ? 1.885 3.940 19.285 1.00 10.53 ? 114 TYR A OH 1 114 UNP O57413 303 Y
ATOM 924 N N . VAL A 1 115 ? -1.199 10.115 14.200 1.00 7.68 ? 115 VAL A N 1 115 UNP O57413 304 V
ATOM 925 C CA . VAL A 1 115 ? -1.898 11.229 13.615 1.00 7.62 ? 115 VAL A CA 1 115 UNP O57413 304 V
ATOM 926 C C . VAL A 1 115 ? -3.176 11.608 14.334 1.00 7.56 ? 115 VAL A C 1 115 UNP O57413 304 V
ATOM 927 O O . VAL A 1 115 ? -4.036 10.750 14.609 1.00 8.19 ? 115 VAL A O 1 115 UNP O57413 304 V
ATOM 928 C CB . VAL A 1 115 ? -2.273 10.945 12.146 1.00 8.68 ? 115 VAL A CB 1 115 UNP O57413 304 V
ATOM 929 C CG1 . VAL A 1 115 ? -3.057 12.106 11.572 1.00 10.38 ? 115 VAL A CG1 1 115 UNP O57413 304 V
ATOM 930 C CG2 . VAL A 1 115 ? -0.999 10.686 11.363 1.00 9.94 ? 115 VAL A CG2 1 115 UNP O57413 304 V
ATOM 931 N N . GLY A 1 116 ? -3.272 12.879 14.688 1.00 6.99 ? 116 GLY A N 1 116 UNP O57413 305 G
ATOM 932 C CA . GLY A 1 116 ? -4.491 13.416 15.261 1.00 7.47 ? 116 GLY A CA 1 116 UNP O57413 305 G
ATOM 933 C C . GLY A 1 116 ? -4.854 12.978 16.647 1.00 7.94 ? 116 GLY A C 1 116 UNP O57413 305 G
ATOM 934 O O . GLY A 1 116 ? -6.037 13.061 16.986 1.00 10.25 ? 116 GLY A O 1 116 UNP O57413 305 G
ATOM 935 N N . ARG A 1 117 ? -3.879 12.584 17.459 1.00 7.31 ? 117 ARG A N 1 117 UNP O57413 306 R
ATOM 936 C CA . ARG A 1 117 ? -4.199 12.113 18.801 1.00 7.62 ? 117 ARG A CA 1 117 UNP O57413 306 R
ATOM 937 C C . ARG A 1 117 ? -3.681 13.013 19.934 1.00 7.04 ? 117 ARG A C 1 117 UNP O57413 306 R
ATOM 938 O O . ARG A 1 117 ? -3.477 12.557 21.064 1.00 6.32 ? 117 ARG A O 1 117 UNP O57413 306 R
ATOM 939 C CB . ARG A 1 117 ? -3.693 10.675 18.993 1.00 8.92 ? 117 ARG A CB 1 117 UNP O57413 306 R
ATOM 940 C CG . ARG A 1 117 ? -4.257 9.628 18.004 1.00 11.95 ? 117 ARG A CG 1 117 UNP O57413 306 R
ATOM 941 C CD . ARG A 1 117 ? -5.749 9.717 17.804 1.00 16.96 ? 117 ARG A CD 1 117 UNP O57413 306 R
ATOM 942 N NE . ARG A 1 117 ? -6.356 8.409 17.569 1.00 22.78 ? 117 ARG A NE 1 117 UNP O57413 306 R
ATOM 943 C CZ . ARG A 1 117 ? -6.575 7.536 18.552 1.00 24.13 ? 117 ARG A CZ 1 117 UNP O57413 306 R
ATOM 944 N NH1 . ARG A 1 117 ? -6.237 7.864 19.785 1.00 25.45 ? 117 ARG A NH1 1 117 UNP O57413 306 R
ATOM 945 N NH2 . ARG A 1 117 ? -7.121 6.360 18.312 1.00 26.25 ? 117 ARG A NH2 1 117 UNP O57413 306 R
ATOM 946 N N . MET A 1 118 ? -3.461 14.287 19.637 1.00 5.94 ? 118 MET A N 1 118 UNP O57413 307 M
ATOM 947 C CA . MET A 1 118 ? -3.041 15.232 20.672 1.00 6.27 ? 118 MET A CA 1 118 UNP O57413 307 M
ATOM 948 C C . MET A 1 118 ? -3.967 15.108 21.898 1.00 6.67 ? 118 MET A C 1 118 UNP O57413 307 M
ATOM 949 O O . MET A 1 118 ? -5.191 15.067 21.764 1.00 8.40 ? 118 MET A O 1 118 UNP O57413 307 M
ATOM 950 C CB . MET A 1 118 ? -3.107 16.650 20.082 1.00 6.40 ? 118 MET A CB 1 118 UNP O57413 307 M
ATOM 951 C CG . MET A 1 118 ? -2.857 17.762 21.110 1.00 6.38 ? 118 MET A CG 1 118 UNP O57413 307 M
ATOM 952 S SD . MET A 1 118 ? -1.226 17.694 21.930 1.00 6.81 ? 118 MET A SD 1 118 UNP O57413 307 M
ATOM 953 C CE . MET A 1 118 ? -0.059 17.751 20.488 1.00 7.13 ? 118 MET A CE 1 118 UNP O57413 307 M
ATOM 954 N N . CYS A 1 119 ? -3.341 15.045 23.069 1.00 6.41 ? 119 CYS A N 1 119 UNP O57413 308 C
ATOM 955 C CA . CYS A 1 119 ? -3.964 14.930 24.402 1.00 7.52 ? 119 CYS A CA 1 119 UNP O57413 308 C
ATOM 956 C C . CYS A 1 119 ? -4.265 13.513 24.845 1.00 7.47 ? 119 CYS A C 1 119 UNP O57413 308 C
ATOM 957 O O . CYS A 1 119 ? -4.448 13.306 26.025 1.00 8.72 ? 119 CYS A O 1 119 UNP O57413 308 C
ATOM 958 C CB . CYS A 1 119 ? -5.244 15.750 24.561 1.00 7.93 ? 119 CYS A CB 1 119 UNP O57413 308 C
ATOM 959 S SG . CYS A 1 119 ? -4.993 17.539 24.365 1.00 10.93 ? 119 CYS A SG 1 119 UNP O57413 308 C
ATOM 960 N N . ASP A 1 120 ? -4.282 12.554 23.924 1.00 7.09 ? 120 ASP A N 1 120 UNP O57413 309 D
ATOM 961 C CA . ASP A 1 120 ? -4.572 11.162 24.307 1.00 7.77 ? 120 ASP A CA 1 120 UNP O57413 309 D
ATOM 962 C C . ASP A 1 120 ? -3.453 10.651 25.205 1.00 7.56 ? 120 ASP A C 1 120 UNP O57413 309 D
ATOM 963 O O . ASP A 1 120 ? -2.278 10.869 24.920 1.00 7.77 ? 120 ASP A O 1 120 UNP O57413 309 D
ATOM 964 C CB . ASP A 1 120 ? -4.686 10.288 23.071 1.00 9.42 ? 120 ASP A CB 1 120 UNP O57413 309 D
ATOM 965 C CG . ASP A 1 120 ? -5.126 8.895 23.399 1.00 12.40 ? 120 ASP A CG 1 120 UNP O57413 309 D
ATOM 966 O OD1 . ASP A 1 120 ? -4.286 8.086 23.820 1.00 11.56 ? 120 ASP A OD1 1 120 UNP O57413 309 D
ATOM 967 O OD2 . ASP A 1 120 ? -6.340 8.638 23.268 1.00 15.70 ? 120 ASP A OD2 1 120 UNP O57413 309 D
ATOM 968 N N . GLU A 1 121 ? -3.800 9.989 26.306 1.00 8.00 ? 121 GLU A N 1 121 UNP O57413 310 E
ATOM 969 C CA . GLU A 1 121 ? -2.766 9.543 27.226 1.00 8.34 ? 121 GLU A CA 1 121 UNP O57413 310 E
ATOM 970 C C . GLU A 1 121 ? -1.694 8.640 26.624 1.00 8.40 ? 121 GLU A C 1 121 UNP O57413 310 E
ATOM 971 O O . GLU A 1 121 ? -0.521 8.753 26.971 1.00 9.85 ? 121 GLU A O 1 121 UNP O57413 310 E
ATOM 972 C CB . GLU A 1 121 ? -3.348 8.786 28.419 1.00 9.86 ? 121 GLU A CB 1 121 UNP O57413 310 E
ATOM 973 C CG . GLU A 1 121 ? -4.161 9.563 29.396 1.00 13.96 ? 121 GLU A CG 1 121 UNP O57413 310 E
ATOM 974 C CD . GLU A 1 121 ? -4.535 8.663 30.569 1.00 16.66 ? 121 GLU A CD 1 121 UNP O57413 310 E
ATOM 975 O OE1 . GLU A 1 121 ? -5.222 7.648 30.337 1.00 19.23 ? 121 GLU A OE1 1 121 UNP O57413 310 E
ATOM 976 O OE2 . GLU A 1 121 ? -4.096 8.955 31.696 1.00 21.76 ? 121 GLU A OE2 1 121 UNP O57413 310 E
ATOM 977 N N . LYS A 1 122 ? -2.089 7.713 25.759 1.00 8.03 ? 122 LYS A N 1 122 UNP O57413 311 K
ATOM 978 C CA . LYS A 1 122 ? -1.118 6.832 25.145 1.00 8.54 ? 122 LYS A CA 1 122 UNP O57413 311 K
ATOM 979 C C . LYS A 1 122 ? -0.647 7.307 23.769 1.00 7.68 ? 122 LYS A C 1 122 UNP O57413 311 K
ATOM 980 O O . LYS A 1 122 ? 0.471 6.967 23.372 1.00 9.54 ? 122 LYS A O 1 122 UNP O57413 311 K
ATOM 981 C CB . LYS A 1 122 ? -1.762 5.445 24.947 1.00 10.28 ? 122 LYS A CB 1 122 UNP O57413 311 K
ATOM 982 C CG . LYS A 1 122 ? -0.902 4.463 24.180 1.00 15.46 ? 122 LYS A CG 1 122 UNP O57413 311 K
ATOM 983 C CD . LYS A 1 122 ? -1.488 3.059 24.153 1.00 17.51 ? 122 LYS A CD 1 122 UNP O57413 311 K
ATOM 984 C CE . LYS A 1 122 ? -0.944 2.260 22.974 1.00 19.08 ? 122 LYS A CE 1 122 UNP O57413 311 K
ATOM 985 N NZ . LYS A 1 122 ? 0.459 2.018 23.092 1.00 17.94 ? 122 LYS A NZ 1 122 UNP O57413 311 K
ATOM 986 N N . TYR A 1 123 ? -1.473 8.072 23.051 1.00 7.26 ? 123 TYR A N 1 123 UNP O57413 312 Y
ATOM 987 C CA . TYR A 1 123 ? -1.137 8.423 21.678 1.00 7.06 ? 123 TYR A CA 1 123 UNP O57413 312 Y
ATOM 988 C C . TYR A 1 123 ? -0.653 9.829 21.392 1.00 5.89 ? 123 TYR A C 1 123 UNP O57413 312 Y
ATOM 989 O O . TYR A 1 123 ? -0.354 10.154 20.236 1.00 5.85 ? 123 TYR A O 1 123 UNP O57413 312 Y
ATOM 990 C CB . TYR A 1 123 ? -2.300 8.046 20.763 1.00 9.03 ? 123 TYR A CB 1 123 UNP O57413 312 Y
ATOM 991 C CG . TYR A 1 123 ? -2.619 6.563 20.844 1.00 11.20 ? 123 TYR A CG 1 123 UNP O57413 312 Y
ATOM 992 C CD1 . TYR A 1 123 ? -3.795 6.100 21.441 1.00 13.43 ? 123 TYR A CD1 1 123 UNP O57413 312 Y
ATOM 993 C CD2 . TYR A 1 123 ? -1.733 5.627 20.317 1.00 13.26 ? 123 TYR A CD2 1 123 UNP O57413 312 Y
ATOM 994 C CE1 . TYR A 1 123 ? -4.063 4.707 21.498 1.00 16.40 ? 123 TYR A CE1 1 123 UNP O57413 312 Y
ATOM 995 C CE2 . TYR A 1 123 ? -1.993 4.256 20.363 1.00 15.89 ? 123 TYR A CE2 1 123 UNP O57413 312 Y
ATOM 996 C CZ . TYR A 1 123 ? -3.156 3.809 20.955 1.00 16.43 ? 123 TYR A CZ 1 123 UNP O57413 312 Y
ATOM 997 O OH . TYR A 1 123 ? -3.396 2.439 20.964 1.00 18.91 ? 123 TYR A OH 1 123 UNP O57413 312 Y
ATOM 998 N N . SER A 1 124 ? -0.619 10.667 22.417 1.00 5.64 ? 124 SER A N 1 124 UNP O57413 313 S
ATOM 999 C CA . SER A 1 124 ? -0.058 12.019 22.237 1.00 4.77 ? 124 SER A CA 1 124 UNP O57413 313 S
ATOM 1000 C C . SER A 1 124 ? 1.476 11.955 22.424 1.00 4.60 ? 124 SER A C 1 124 UNP O57413 313 S
ATOM 1001 O O . SER A 1 124 ? 2.052 12.504 23.390 1.00 4.88 ? 124 SER A O 1 124 UNP O57413 313 S
ATOM 1002 C CB . SER A 1 124 ? -0.649 12.967 23.257 1.00 5.45 ? 124 SER A CB 1 124 UNP O57413 313 S
ATOM 1003 O OG . SER A 1 124 ? -0.395 14.313 22.845 1.00 5.49 ? 124 SER A OG 1 124 UNP O57413 313 S
ATOM 1004 N N . VAL A 1 125 ? 2.108 11.233 21.495 1.00 5.00 ? 125 VAL A N 1 125 UNP O57413 314 V
ATOM 1005 C CA . VAL A 1 125 ? 3.548 11.054 21.555 1.00 5.18 ? 125 VAL A CA 1 125 UNP O57413 314 V
ATOM 1006 C C . VAL A 1 125 ? 4.162 11.007 20.181 1.00 5.24 ? 125 VAL A C 1 125 UNP O57413 314 V
ATOM 1007 O O . VAL A 1 125 ? 3.467 10.775 19.177 1.00 6.27 ? 125 VAL A O 1 125 UNP O57413 314 V
ATOM 1008 C CB . VAL A 1 125 ? 3.953 9.706 22.266 1.00 5.41 ? 125 VAL A CB 1 125 UNP O57413 314 V
ATOM 1009 C CG1 . VAL A 1 125 ? 3.439 9.689 23.705 1.00 6.06 ? 125 VAL A CG1 1 125 UNP O57413 314 V
ATOM 1010 C CG2 . VAL A 1 125 ? 3.435 8.486 21.495 1.00 5.54 ? 125 VAL A CG2 1 125 UNP O57413 314 V
ATOM 1011 N N . ALA A 1 126 ? 5.483 11.224 20.167 1.00 5.06 ? 126 ALA A N 1 126 UNP O57413 315 A
ATOM 1012 C CA . ALA A 1 126 ? 6.294 11.096 18.969 1.00 4.98 ? 126 ALA A CA 1 126 UNP O57413 315 A
ATOM 1013 C C . ALA A 1 126 ? 7.655 10.550 19.382 1.00 4.25 ? 126 ALA A C 1 126 UNP O57413 315 A
ATOM 1014 O O . ALA A 1 126 ? 8.046 10.669 20.551 1.00 4.46 ? 126 ALA A O 1 126 UNP O57413 315 A
ATOM 1015 C CB . ALA A 1 126 ? 6.504 12.448 18.289 1.00 5.83 ? 126 ALA A CB 1 126 UNP O57413 315 A
ATOM 1016 N N . VAL A 1 127 ? 8.356 9.939 18.425 1.00 4.01 ? 127 VAL A N 1 127 UNP O57413 316 V
ATOM 1017 C CA . VAL A 1 127 ? 9.734 9.513 18.648 1.00 4.56 ? 127 VAL A CA 1 127 UNP O57413 316 V
ATOM 1018 C C . VAL A 1 127 ? 10.549 10.236 17.584 1.00 3.98 ? 127 VAL A C 1 127 UNP O57413 316 V
ATOM 1019 O O . VAL A 1 127 ? 10.106 10.334 16.420 1.00 4.81 ? 127 VAL A O 1 127 UNP O57413 316 V
ATOM 1020 C CB . VAL A 1 127 ? 9.906 7.971 18.609 1.00 5.23 ? 127 VAL A CB 1 127 UNP O57413 316 V
ATOM 1021 C CG1 . VAL A 1 127 ? 9.020 7.339 19.664 1.00 6.60 ? 127 VAL A CG1 1 127 UNP O57413 316 V
ATOM 1022 C CG2 . VAL A 1 127 ? 9.572 7.399 17.230 1.00 6.69 ? 127 VAL A CG2 1 127 UNP O57413 316 V
ATOM 1023 N N . VAL A 1 128 ? 11.705 10.768 17.969 1.00 4.50 ? 128 VAL A N 1 128 UNP O57413 317 V
ATOM 1024 C CA . VAL A 1 128 ? 12.500 11.566 17.050 1.00 4.44 ? 128 VAL A CA 1 128 UNP O57413 317 V
ATOM 1025 C C . VAL A 1 128 ? 13.974 11.237 17.202 1.00 4.46 ? 128 VAL A C 1 128 UNP O57413 317 V
ATOM 1026 O O . VAL A 1 128 ? 14.489 11.145 18.315 1.00 4.82 ? 128 VAL A O 1 128 UNP O57413 317 V
ATOM 1027 C CB . VAL A 1 128 ? 12.277 13.092 17.354 1.00 4.82 ? 128 VAL A CB 1 128 UNP O57413 317 V
ATOM 1028 C CG1 . VAL A 1 128 ? 13.281 13.964 16.522 1.00 5.83 ? 128 VAL A CG1 1 128 UNP O57413 317 V
ATOM 1029 C CG2 . VAL A 1 128 ? 10.835 13.486 17.044 1.00 6.57 ? 128 VAL A CG2 1 128 UNP O57413 317 V
ATOM 1030 N N . LYS A 1 129 ? 14.646 11.042 16.075 1.00 4.74 ? 129 LYS A N 1 129 UNP O57413 318 K
ATOM 1031 C CA . LYS A 1 129 ? 16.046 10.755 16.071 1.00 4.63 ? 129 LYS A CA 1 129 UNP O57413 318 K
ATOM 1032 C C . LYS A 1 129 ? 16.821 12.062 16.106 1.00 4.96 ? 129 LYS A C 1 129 UNP O57413 318 K
ATOM 1033 O O . LYS A 1 129 ? 16.475 12.986 15.380 1.00 6.42 ? 129 LYS A O 1 129 UNP O57413 318 K
ATOM 1034 C CB . LYS A 1 129 ? 16.388 9.999 14.780 1.00 5.03 ? 129 LYS A CB 1 129 UNP O57413 318 K
ATOM 1035 C CG . LYS A 1 129 ? 17.851 9.563 14.718 1.00 6.18 ? 129 LYS A CG 1 129 UNP O57413 318 K
ATOM 1036 C CD . LYS A 1 129 ? 18.165 8.856 13.409 1.00 7.14 ? 129 LYS A CD 1 129 UNP O57413 318 K
ATOM 1037 C CE . LYS A 1 129 ? 19.579 8.344 13.386 1.00 8.98 ? 129 LYS A CE 1 129 UNP O57413 318 K
ATOM 1038 N NZ . LYS A 1 129 ? 19.907 7.650 12.087 1.00 10.92 ? 129 LYS A NZ 1 129 UNP O57413 318 K
ATOM 1039 N N . ASP A 1 130 ? 17.859 12.129 16.949 1.00 4.81 ? 130 ASP A N 1 130 UNP O57413 319 D
ATOM 1040 C CA . ASP A 1 130 ? 18.733 13.322 17.017 1.00 5.84 ? 130 ASP A CA 1 130 UNP O57413 319 D
ATOM 1041 C C . ASP A 1 130 ? 19.680 13.143 15.816 1.00 6.47 ? 130 ASP A C 1 130 UNP O57413 319 D
ATOM 1042 O O . ASP A 1 130 ? 20.859 12.807 15.957 1.00 9.17 ? 130 ASP A O 1 130 UNP O57413 319 D
ATOM 1043 C CB . ASP A 1 130 ? 19.495 13.266 18.344 1.00 7.07 ? 130 ASP A CB 1 130 UNP O57413 319 D
ATOM 1044 C CG . ASP A 1 130 ? 20.278 14.518 18.604 1.00 8.05 ? 130 ASP A CG 1 130 UNP O57413 319 D
ATOM 1045 O OD1 . ASP A 1 130 ? 21.472 14.377 18.931 1.00 10.36 ? 130 ASP A OD1 1 130 UNP O57413 319 D
ATOM 1046 O OD2 . ASP A 1 130 ? 19.713 15.621 18.497 1.00 8.93 ? 130 ASP A OD2 1 130 UNP O57413 319 D
ATOM 1047 N N . HIS A 1 131 ? 19.126 13.375 14.624 1.00 6.28 ? 131 HIS A N 1 131 UNP O57413 320 H
ATOM 1048 C CA . HIS A 1 131 ? 19.790 13.050 13.350 1.00 6.19 ? 131 HIS A CA 1 131 UNP O57413 320 H
ATOM 1049 C C . HIS A 1 131 ? 20.672 14.072 12.672 1.00 7.27 ? 131 HIS A C 1 131 UNP O57413 320 H
ATOM 1050 O O . HIS A 1 131 ? 21.087 13.862 11.510 1.00 8.77 ? 131 HIS A O 1 131 UNP O57413 320 H
ATOM 1051 C CB . HIS A 1 131 ? 18.725 12.594 12.351 1.00 6.37 ? 131 HIS A CB 1 131 UNP O57413 320 H
ATOM 1052 C CG . HIS A 1 131 ? 17.800 13.688 11.922 1.00 6.11 ? 131 HIS A CG 1 131 UNP O57413 320 H
ATOM 1053 N ND1 . HIS A 1 131 ? 18.074 14.508 10.840 1.00 6.37 ? 131 HIS A ND1 1 131 UNP O57413 320 H
ATOM 1054 C CD2 . HIS A 1 131 ? 16.617 14.103 12.439 1.00 6.63 ? 131 HIS A CD2 1 131 UNP O57413 320 H
ATOM 1055 C CE1 . HIS A 1 131 ? 17.081 15.386 10.724 1.00 5.83 ? 131 HIS A CE1 1 131 UNP O57413 320 H
ATOM 1056 N NE2 . HIS A 1 131 ? 16.188 15.157 11.680 1.00 7.16 ? 131 HIS A NE2 1 131 UNP O57413 320 H
ATOM 1057 N N . SER A 1 132 ? 20.969 15.157 13.367 1.00 6.56 ? 132 SER A N 1 132 UNP O57413 321 S
ATOM 1058 C CA . SER A 1 132 ? 21.828 16.206 12.813 1.00 7.70 ? 132 SER A CA 1 132 UNP O57413 321 S
ATOM 1059 C C . SER A 1 132 ? 22.464 16.972 13.955 1.00 8.74 ? 132 SER A C 1 132 UNP O57413 321 S
ATOM 1060 O O . SER A 1 132 ? 21.881 17.092 15.022 1.00 8.52 ? 132 SER A O 1 132 UNP O57413 321 S
ATOM 1061 C CB . SER A 1 132 ? 20.978 17.194 12.017 1.00 7.12 ? 132 SER A CB 1 132 UNP O57413 321 S
ATOM 1062 O OG . SER A 1 132 ? 21.756 18.286 11.490 1.00 8.56 ? 132 SER A OG 1 132 UNP O57413 321 S
ATOM 1063 N N . SER A 1 133 ? 23.653 17.514 13.718 1.00 10.34 ? 133 SER A N 1 133 UNP O57413 322 S
ATOM 1064 C CA . SER A 1 133 ? 24.280 18.336 14.725 1.00 11.16 ? 133 SER A CA 1 133 UNP O57413 322 S
ATOM 1065 C C . SER A 1 133 ? 23.532 19.672 14.721 1.00 10.53 ? 133 SER A C 1 133 UNP O57413 322 S
ATOM 1066 O O . SER A 1 133 ? 23.592 20.379 15.724 1.00 13.24 ? 133 SER A O 1 133 UNP O57413 322 S
ATOM 1067 C CB . SER A 1 133 ? 25.767 18.555 14.393 1.00 12.63 ? 133 SER A CB 1 133 UNP O57413 322 S
ATOM 1068 O OG . SER A 1 133 ? 25.927 19.086 13.108 1.00 14.47 ? 133 SER A OG 1 133 UNP O57413 322 S
ATOM 1069 N N . LYS A 1 134 ? 22.834 20.014 13.632 1.00 9.66 ? 134 LYS A N 1 134 UNP O57413 323 K
ATOM 1070 C CA . LYS A 1 134 ? 22.094 21.290 13.543 1.00 9.45 ? 134 LYS A CA 1 134 UNP O57413 323 K
ATOM 1071 C C . LYS A 1 134 ? 20.788 21.173 14.318 1.00 7.53 ? 134 LYS A C 1 134 UNP O57413 323 K
ATOM 1072 O O . LYS A 1 134 ? 19.876 20.418 13.938 1.00 8.16 ? 134 LYS A O 1 134 UNP O57413 323 K
ATOM 1073 C CB . LYS A 1 134 ? 21.773 21.618 12.090 1.00 11.24 ? 134 LYS A CB 1 134 UNP O57413 323 K
ATOM 1074 C CG . LYS A 1 134 ? 23.010 21.794 11.187 1.00 13.10 ? 134 LYS A CG 1 134 UNP O57413 323 K
ATOM 1075 C CD . LYS A 1 134 ? 22.594 22.087 9.770 1.00 16.40 ? 134 LYS A CD 1 134 UNP O57413 323 K
ATOM 1076 C CE . LYS A 1 134 ? 23.805 22.276 8.881 1.00 18.96 ? 134 LYS A CE 1 134 UNP O57413 323 K
ATOM 1077 N NZ . LYS A 1 134 ? 23.389 22.461 7.473 1.00 22.66 ? 134 LYS A NZ 1 134 UNP O57413 323 K
ATOM 1078 N N . VAL A 1 135 ? 20.716 21.911 15.408 1.00 6.60 ? 135 VAL A N 1 135 UNP O57413 324 V
ATOM 1079 C CA . VAL A 1 135 ? 19.535 21.925 16.261 1.00 6.11 ? 135 VAL A CA 1 135 UNP O57413 324 V
ATOM 1080 C C . VAL A 1 135 ? 18.259 22.154 15.464 1.00 5.61 ? 135 VAL A C 1 135 UNP O57413 324 V
ATOM 1081 O O . VAL A 1 135 ? 17.256 21.459 15.698 1.00 5.47 ? 135 VAL A O 1 135 UNP O57413 324 V
ATOM 1082 C CB . VAL A 1 135 ? 19.672 23.020 17.340 1.00 7.68 ? 135 VAL A CB 1 135 UNP O57413 324 V
ATOM 1083 C CG1 . VAL A 1 135 ? 18.384 23.205 18.122 1.00 8.44 ? 135 VAL A CG1 1 135 UNP O57413 324 V
ATOM 1084 C CG2 . VAL A 1 135 ? 20.812 22.656 18.278 1.00 10.37 ? 135 VAL A CG2 1 135 UNP O57413 324 V
ATOM 1085 N N . PHE A 1 136 ? 18.285 23.070 14.508 1.00 5.27 ? 136 PHE A N 1 136 UNP O57413 325 F
ATOM 1086 C CA . PHE A 1 136 ? 17.060 23.321 13.783 1.00 4.96 ? 136 PHE A CA 1 136 UNP O57413 325 F
ATOM 1087 C C . PHE A 1 136 ? 16.570 22.098 13.020 1.00 5.30 ? 136 PHE A C 1 136 UNP O57413 325 F
ATOM 1088 O O . PHE A 1 136 ? 15.350 21.882 12.921 1.00 4.68 ? 136 PHE A O 1 136 UNP O57413 325 F
ATOM 1089 C CB . PHE A 1 136 ? 17.214 24.505 12.813 1.00 5.85 ? 136 PHE A CB 1 136 UNP O57413 325 F
ATOM 1090 C CG . PHE A 1 136 ? 15.971 24.785 12.014 1.00 5.19 ? 136 PHE A CG 1 136 UNP O57413 325 F
ATOM 1091 C CD1 . PHE A 1 136 ? 14.936 25.494 12.561 1.00 6.73 ? 136 PHE A CD1 1 136 UNP O57413 325 F
ATOM 1092 C CD2 . PHE A 1 136 ? 15.823 24.285 10.747 1.00 6.32 ? 136 PHE A CD2 1 136 UNP O57413 325 F
ATOM 1093 C CE1 . PHE A 1 136 ? 13.768 25.708 11.845 1.00 7.99 ? 136 PHE A CE1 1 136 UNP O57413 325 F
ATOM 1094 C CE2 . PHE A 1 136 ? 14.664 24.493 10.033 1.00 7.02 ? 136 PHE A CE2 1 136 UNP O57413 325 F
ATOM 1095 C CZ . PHE A 1 136 ? 13.638 25.208 10.593 1.00 7.38 ? 136 PHE A CZ 1 136 UNP O57413 325 F
ATOM 1096 N N . MET A 1 137 ? 17.478 21.313 12.440 1.00 4.57 ? 137 MET A N 1 137 UNP O57413 326 M
ATOM 1097 C CA . MET A 1 137 ? 17.029 20.132 11.706 1.00 5.65 ? 137 MET A CA 1 137 UNP O57413 326 M
ATOM 1098 C C . MET A 1 137 ? 16.318 19.127 12.591 1.00 4.90 ? 137 MET A C 1 137 UNP O57413 326 M
ATOM 1099 O O . MET A 1 137 ? 15.365 18.487 12.152 1.00 6.16 ? 137 MET A O 1 137 UNP O57413 326 M
ATOM 1100 C CB . MET A 1 137 ? 18.202 19.489 10.974 1.00 8.20 ? 137 MET A CB 1 137 UNP O57413 326 M
ATOM 1101 C CG . MET A 1 137 ? 18.728 20.446 9.888 1.00 10.10 ? 137 MET A CG 1 137 UNP O57413 326 M
ATOM 1102 S SD . MET A 1 137 ? 17.473 20.844 8.599 1.00 19.06 ? 137 MET A SD 1 137 UNP O57413 326 M
ATOM 1103 C CE . MET A 1 137 ? 17.765 19.542 7.986 1.00 10.45 ? 137 MET A CE 1 137 UNP O57413 326 M
ATOM 1104 N N . VAL A 1 138 ? 16.756 18.985 13.840 1.00 4.26 ? 138 VAL A N 1 138 UNP O57413 327 V
ATOM 1105 C CA . VAL A 1 138 ? 16.076 18.086 14.752 1.00 3.99 ? 138 VAL A CA 1 138 UNP O57413 327 V
ATOM 1106 C C . VAL A 1 138 ? 14.771 18.774 15.226 1.00 3.93 ? 138 VAL A C 1 138 UNP O57413 327 V
ATOM 1107 O O . VAL A 1 138 ? 13.719 18.134 15.289 1.00 4.14 ? 138 VAL A O 1 138 UNP O57413 327 V
ATOM 1108 C CB . VAL A 1 138 ? 16.987 17.699 15.925 1.00 4.50 ? 138 VAL A CB 1 138 UNP O57413 327 V
ATOM 1109 C CG1 . VAL A 1 138 ? 16.263 16.771 16.855 1.00 6.21 ? 138 VAL A CG1 1 138 UNP O57413 327 V
ATOM 1110 C CG2 . VAL A 1 138 ? 18.261 17.019 15.374 1.00 6.34 ? 138 VAL A CG2 1 138 UNP O57413 327 V
ATOM 1111 N N . ALA A 1 139 ? 14.818 20.072 15.543 1.00 3.84 ? 139 ALA A N 1 139 UNP O57413 328 A
ATOM 1112 C CA . ALA A 1 139 ? 13.597 20.762 16.013 1.00 3.63 ? 139 ALA A CA 1 139 UNP O57413 328 A
ATOM 1113 C C . ALA A 1 139 ? 12.501 20.744 14.955 1.00 3.30 ? 139 ALA A C 1 139 UNP O57413 328 A
ATOM 1114 O O . ALA A 1 139 ? 11.331 20.621 15.309 1.00 4.05 ? 139 ALA A O 1 139 UNP O57413 328 A
ATOM 1115 C CB . ALA A 1 139 ? 13.934 22.195 16.375 1.00 4.54 ? 139 ALA A CB 1 139 UNP O57413 328 A
ATOM 1116 N N . VAL A 1 140 ? 12.862 20.906 13.679 1.00 2.94 ? 140 VAL A N 1 140 UNP O57413 329 V
ATOM 1117 C CA . VAL A 1 140 ? 11.802 20.892 12.659 1.00 3.13 ? 140 VAL A CA 1 140 UNP O57413 329 V
ATOM 1118 C C . VAL A 1 140 ? 11.213 19.466 12.516 1.00 3.29 ? 140 VAL A C 1 140 UNP O57413 329 V
ATOM 1119 O O . VAL A 1 140 ? 10.034 19.299 12.159 1.00 3.75 ? 140 VAL A O 1 140 UNP O57413 329 V
ATOM 1120 C CB . VAL A 1 140 ? 12.301 21.515 11.312 1.00 3.40 ? 140 VAL A CB 1 140 UNP O57413 329 V
ATOM 1121 C CG1 . VAL A 1 140 ? 13.221 20.585 10.569 1.00 4.46 ? 140 VAL A CG1 1 140 UNP O57413 329 V
ATOM 1122 C CG2 . VAL A 1 140 ? 11.086 21.933 10.465 1.00 5.00 ? 140 VAL A CG2 1 140 UNP O57413 329 V
ATOM 1123 N N . THR A 1 141 ? 12.019 18.453 12.845 1.00 2.77 ? 141 THR A N 1 141 UNP O57413 330 T
ATOM 1124 C CA . THR A 1 141 ? 11.511 17.076 12.837 1.00 3.02 ? 141 THR A CA 1 141 UNP O57413 330 T
ATOM 1125 C C . THR A 1 141 ? 10.528 16.912 14.007 1.00 2.88 ? 141 THR A C 1 141 UNP O57413 330 T
ATOM 1126 O O . THR A 1 141 ? 9.452 16.330 13.818 1.00 3.15 ? 141 THR A O 1 141 UNP O57413 330 T
ATOM 1127 C CB . THR A 1 141 ? 12.662 16.097 12.958 1.00 2.98 ? 141 THR A CB 1 141 UNP O57413 330 T
ATOM 1128 O OG1 . THR A 1 141 ? 13.556 16.303 11.843 1.00 5.56 ? 141 THR A OG1 1 141 UNP O57413 330 T
ATOM 1129 C CG2 . THR A 1 141 ? 12.143 14.680 12.907 1.00 4.28 ? 141 THR A CG2 1 141 UNP O57413 330 T
ATOM 1130 N N . MET A 1 142 ? 10.891 17.440 15.183 1.00 2.99 ? 142 MET A N 1 142 UNP O57413 331 M
ATOM 1131 C CA . MET A 1 142 ? 9.968 17.380 16.327 1.00 3.05 ? 142 MET A CA 1 142 UNP O57413 331 M
ATOM 1132 C C . MET A 1 142 ? 8.649 18.117 15.994 1.00 3.63 ? 142 MET A C 1 142 UNP O57413 331 M
ATOM 1133 O O . MET A 1 142 ? 7.552 17.662 16.340 1.00 3.89 ? 142 MET A O 1 142 UNP O57413 331 M
ATOM 1134 C CB . MET A 1 142 ? 10.591 18.052 17.570 1.00 4.01 ? 142 MET A CB 1 142 UNP O57413 331 M
ATOM 1135 C CG . MET A 1 142 ? 11.830 17.295 18.027 1.00 3.81 ? 142 MET A CG 1 142 UNP O57413 331 M
ATOM 1136 S SD . MET A 1 142 ? 12.795 18.170 19.272 1.00 7.02 ? 142 MET A SD 1 142 UNP O57413 331 M
ATOM 1137 C CE . MET A 1 142 ? 11.913 17.848 20.641 1.00 9.81 ? 142 MET A CE 1 142 UNP O57413 331 M
ATOM 1138 N N . THR A 1 143 ? 8.757 19.242 15.287 1.00 2.77 ? 143 THR A N 1 143 UNP O57413 332 T
ATOM 1139 C CA . THR A 1 143 ? 7.598 20.056 14.917 1.00 3.41 ? 143 THR A CA 1 143 UNP O57413 332 T
ATOM 1140 C C . THR A 1 143 ? 6.742 19.344 13.859 1.00 3.30 ? 143 THR A C 1 143 UNP O57413 332 T
ATOM 1141 O O . THR A 1 143 ? 5.512 19.395 13.922 1.00 4.01 ? 143 THR A O 1 143 UNP O57413 332 T
ATOM 1142 C CB . THR A 1 143 ? 8.054 21.447 14.433 1.00 4.02 ? 143 THR A CB 1 143 UNP O57413 332 T
ATOM 1143 O OG1 . THR A 1 143 ? 8.838 22.056 15.474 1.00 3.89 ? 143 THR A OG1 1 143 UNP O57413 332 T
ATOM 1144 C CG2 . THR A 1 143 ? 6.854 22.362 14.213 1.00 4.25 ? 143 THR A CG2 1 143 UNP O57413 332 T
ATOM 1145 N N . HIS A 1 144 ? 7.385 18.675 12.890 1.00 3.19 ? 144 HIS A N 1 144 UNP O57413 333 H
ATOM 1146 C CA . HIS A 1 144 ? 6.673 17.892 11.870 1.00 3.30 ? 144 HIS A CA 1 144 UNP O57413 333 H
ATOM 1147 C C . HIS A 1 144 ? 5.854 16.770 12.581 1.00 2.93 ? 144 HIS A C 1 144 UNP O57413 333 H
ATOM 1148 O O . HIS A 1 144 ? 4.666 16.562 12.279 1.00 3.59 ? 144 HIS A O 1 144 UNP O57413 333 H
ATOM 1149 C CB . HIS A 1 144 ? 7.736 17.279 10.941 1.00 3.96 ? 144 HIS A CB 1 144 UNP O57413 333 H
ATOM 1150 C CG . HIS A 1 144 ? 7.186 16.368 9.887 1.00 3.12 ? 144 HIS A CG 1 144 UNP O57413 333 H
ATOM 1151 N ND1 . HIS A 1 144 ? 7.015 16.758 8.582 1.00 3.00 ? 144 HIS A ND1 1 144 UNP O57413 333 H
ATOM 1152 C CD2 . HIS A 1 144 ? 6.796 15.071 9.950 1.00 3.09 ? 144 HIS A CD2 1 144 UNP O57413 333 H
ATOM 1153 C CE1 . HIS A 1 144 ? 6.564 15.724 7.872 1.00 4.24 ? 144 HIS A CE1 1 144 UNP O57413 333 H
ATOM 1154 N NE2 . HIS A 1 144 ? 6.411 14.683 8.686 1.00 3.29 ? 144 HIS A NE2 1 144 UNP O57413 333 H
ATOM 1155 N N . GLU A 1 145 ? 6.470 16.055 13.536 1.00 2.88 ? 145 GLU A N 1 145 UNP O57413 334 E
ATOM 1156 C CA . GLU A 1 145 ? 5.723 14.998 14.246 1.00 3.56 ? 145 GLU A CA 1 145 UNP O57413 334 E
ATOM 1157 C C . GLU A 1 145 ? 4.596 15.591 15.113 1.00 3.91 ? 145 GLU A C 1 145 UNP O57413 334 E
ATOM 1158 O O . GLU A 1 145 ? 3.509 15.017 15.219 1.00 4.37 ? 145 GLU A O 1 145 UNP O57413 334 E
ATOM 1159 C CB . GLU A 1 145 ? 6.676 14.115 15.087 1.00 4.91 ? 145 GLU A CB 1 145 UNP O57413 334 E
ATOM 1160 C CG . GLU A 1 145 ? 7.845 13.551 14.263 1.00 4.59 ? 145 GLU A CG 1 145 UNP O57413 334 E
ATOM 1161 C CD . GLU A 1 145 ? 7.433 12.796 13.015 1.00 5.31 ? 145 GLU A CD 1 145 UNP O57413 334 E
ATOM 1162 O OE1 . GLU A 1 145 ? 8.320 12.667 12.109 1.00 5.01 ? 145 GLU A OE1 1 145 UNP O57413 334 E
ATOM 1163 O OE2 . GLU A 1 145 ? 6.272 12.331 12.903 1.00 5.37 ? 145 GLU A OE2 1 145 UNP O57413 334 E
ATOM 1164 N N . LEU A 1 146 ? 4.862 16.738 15.751 1.00 3.35 ? 146 LEU A N 1 146 UNP O57413 335 L
ATOM 1165 C CA . LEU A 1 146 ? 3.821 17.427 16.511 1.00 4.10 ? 146 LEU A CA 1 146 UNP O57413 335 L
ATOM 1166 C C . LEU A 1 146 ? 2.674 17.768 15.552 1.00 4.21 ? 146 LEU A C 1 146 UNP O57413 335 L
ATOM 1167 O O . LEU A 1 146 ? 1.480 17.598 15.907 1.00 4.75 ? 146 LEU A O 1 146 UNP O57413 335 L
ATOM 1168 C CB . LEU A 1 146 ? 4.395 18.703 17.123 1.00 5.36 ? 146 LEU A CB 1 146 UNP O57413 335 L
ATOM 1169 C CG . LEU A 1 146 ? 3.439 19.502 18.015 1.00 5.42 ? 146 LEU A CG 1 146 UNP O57413 335 L
ATOM 1170 C CD1 . LEU A 1 146 ? 3.164 18.722 19.318 1.00 7.85 ? 146 LEU A CD1 1 146 UNP O57413 335 L
ATOM 1171 C CD2 . LEU A 1 146 ? 4.095 20.840 18.398 1.00 6.63 ? 146 LEU A CD2 1 146 UNP O57413 335 L
ATOM 1172 N N . GLY A 1 147 ? 3.000 18.284 14.366 1.00 3.64 ? 147 GLY A N 1 147 UNP O57413 336 G
ATOM 1173 C CA . GLY A 1 147 ? 1.969 18.609 13.370 1.00 4.99 ? 147 GLY A CA 1 147 UNP O57413 336 G
ATOM 1174 C C . GLY A 1 147 ? 1.131 17.390 13.052 1.00 3.89 ? 147 GLY A C 1 147 UNP O57413 336 G
ATOM 1175 O O . GLY A 1 147 ? -0.106 17.482 12.986 1.00 4.58 ? 147 GLY A O 1 147 UNP O57413 336 G
ATOM 1176 N N . HIS A 1 148 ? 1.774 16.241 12.821 1.00 4.18 ? 148 HIS A N 1 148 UNP O57413 337 H
ATOM 1177 C CA . HIS A 1 148 ? 0.968 15.036 12.608 1.00 4.20 ? 148 HIS A CA 1 148 UNP O57413 337 H
ATOM 1178 C C . HIS A 1 148 ? 0.024 14.788 13.789 1.00 5.35 ? 148 HIS A C 1 148 UNP O57413 337 H
ATOM 1179 O O . HIS A 1 148 ? -1.138 14.451 13.588 1.00 5.72 ? 148 HIS A O 1 148 UNP O57413 337 H
ATOM 1180 C CB . HIS A 1 148 ? 1.839 13.776 12.473 1.00 4.86 ? 148 HIS A CB 1 148 UNP O57413 337 H
ATOM 1181 C CG . HIS A 1 148 ? 2.450 13.580 11.124 1.00 5.11 ? 148 HIS A CG 1 148 UNP O57413 337 H
ATOM 1182 N ND1 . HIS A 1 148 ? 1.706 13.579 9.961 1.00 4.94 ? 148 HIS A ND1 1 148 UNP O57413 337 H
ATOM 1183 C CD2 . HIS A 1 148 ? 3.714 13.254 10.760 1.00 4.57 ? 148 HIS A CD2 1 148 UNP O57413 337 H
ATOM 1184 C CE1 . HIS A 1 148 ? 2.488 13.251 8.943 1.00 4.44 ? 148 HIS A CE1 1 148 UNP O57413 337 H
ATOM 1185 N NE2 . HIS A 1 148 ? 3.714 13.048 9.397 1.00 4.77 ? 148 HIS A NE2 1 148 UNP O57413 337 H
ATOM 1186 N N . ASN A 1 149 ? 0.528 14.942 15.014 1.00 4.57 ? 149 ASN A N 1 149 UNP O57413 338 N
ATOM 1187 C CA . ASN A 1 149 ? -0.307 14.667 16.192 1.00 4.24 ? 149 ASN A CA 1 149 UNP O57413 338 N
ATOM 1188 C C . ASN A 1 149 ? -1.471 15.669 16.297 1.00 5.19 ? 149 ASN A C 1 149 UNP O57413 338 N
ATOM 1189 O O . ASN A 1 149 ? -2.485 15.372 16.955 1.00 5.64 ? 149 ASN A O 1 149 UNP O57413 338 N
ATOM 1190 C CB . ASN A 1 149 ? 0.591 14.627 17.448 1.00 5.47 ? 149 ASN A CB 1 149 UNP O57413 338 N
ATOM 1191 C CG . ASN A 1 149 ? 0.034 13.748 18.562 1.00 5.51 ? 149 ASN A CG 1 149 UNP O57413 338 N
ATOM 1192 O OD1 . ASN A 1 149 ? -0.120 14.200 19.707 1.00 5.00 ? 149 ASN A OD1 1 149 UNP O57413 338 N
ATOM 1193 N ND2 . ASN A 1 149 ? -0.247 12.480 18.251 1.00 6.09 ? 149 ASN A ND2 1 149 UNP O57413 338 N
ATOM 1194 N N . LEU A 1 150 ? -1.330 16.844 15.650 1.00 4.70 ? 150 LEU A N 1 150 UNP O57413 339 L
ATOM 1195 C CA . LEU A 1 150 ? -2.390 17.873 15.562 1.00 5.84 ? 150 LEU A CA 1 150 UNP O57413 339 L
ATOM 1196 C C . LEU A 1 150 ? -3.278 17.671 14.335 1.00 6.31 ? 150 LEU A C 1 150 UNP O57413 339 L
ATOM 1197 O O . LEU A 1 150 ? -3.978 18.607 13.930 1.00 7.03 ? 150 LEU A O 1 150 UNP O57413 339 L
ATOM 1198 C CB . LEU A 1 150 ? -1.785 19.287 15.559 1.00 6.01 ? 150 LEU A CB 1 150 UNP O57413 339 L
ATOM 1199 C CG . LEU A 1 150 ? -1.117 19.655 16.880 1.00 6.15 ? 150 LEU A CG 1 150 UNP O57413 339 L
ATOM 1200 C CD1 . LEU A 1 150 ? -0.247 20.905 16.705 1.00 7.38 ? 150 LEU A CD1 1 150 UNP O57413 339 L
ATOM 1201 C CD2 . LEU A 1 150 ? -2.175 19.961 17.981 1.00 6.82 ? 150 LEU A CD2 1 150 UNP O57413 339 L
ATOM 1202 N N . GLY A 1 151 ? -3.229 16.472 13.731 1.00 5.66 ? 151 GLY A N 1 151 UNP O57413 340 G
ATOM 1203 C CA . GLY A 1 151 ? -4.104 16.147 12.603 1.00 6.98 ? 151 GLY A CA 1 151 UNP O57413 340 G
ATOM 1204 C C . GLY A 1 151 ? -3.613 16.495 11.217 1.00 6.89 ? 151 GLY A C 1 151 UNP O57413 340 G
ATOM 1205 O O . GLY A 1 151 ? -4.387 16.456 10.267 1.00 8.28 ? 151 GLY A O 1 151 UNP O57413 340 G
ATOM 1206 N N . MET A 1 152 ? -2.348 16.849 11.068 1.00 5.97 ? 152 MET A N 1 152 UNP O57413 341 M
ATOM 1207 C CA . MET A 1 152 ? -1.833 17.197 9.751 1.00 5.86 ? 152 MET A CA 1 152 UNP O57413 341 M
ATOM 1208 C C . MET A 1 152 ? -1.268 16.000 9.027 1.00 6.18 ? 152 MET A C 1 152 UNP O57413 341 M
ATOM 1209 O O . MET A 1 152 ? -0.638 15.134 9.648 1.00 6.58 ? 152 MET A O 1 152 UNP O57413 341 M
ATOM 1210 C CB . MET A 1 152 ? -0.694 18.225 9.882 1.00 5.60 ? 152 MET A CB 1 152 UNP O57413 341 M
ATOM 1211 C CG . MET A 1 152 ? -1.106 19.510 10.575 1.00 5.63 ? 152 MET A CG 1 152 UNP O57413 341 M
ATOM 1212 S SD . MET A 1 152 ? 0.374 20.550 10.818 1.00 5.04 ? 152 MET A SD 1 152 UNP O57413 341 M
ATOM 1213 C CE . MET A 1 152 ? -0.358 21.909 11.738 1.00 7.08 ? 152 MET A CE 1 152 UNP O57413 341 M
ATOM 1214 N N . GLU A 1 153 ? -1.550 15.930 7.723 1.00 5.90 ? 153 GLU A N 1 153 UNP O57413 342 E
ATOM 1215 C CA . GLU A 1 153 ? -0.920 14.948 6.842 1.00 6.02 ? 153 GLU A CA 1 153 UNP O57413 342 E
ATOM 1216 C C . GLU A 1 153 ? 0.159 15.700 6.074 1.00 5.77 ? 153 GLU A C 1 153 UNP O57413 342 E
ATOM 1217 O O . GLU A 1 153 ? 0.339 16.907 6.240 1.00 6.57 ? 153 GLU A O 1 153 UNP O57413 342 E
ATOM 1218 C CB . GLU A 1 153 ? -1.928 14.351 5.849 1.00 7.64 ? 153 GLU A CB 1 153 UNP O57413 342 E
ATOM 1219 C CG . GLU A 1 153 ? -3.101 13.620 6.527 1.00 10.83 ? 153 GLU A CG 1 153 UNP O57413 342 E
ATOM 1220 C CD . GLU A 1 153 ? -2.700 12.321 7.269 1.00 13.40 ? 153 GLU A CD 1 153 UNP O57413 342 E
ATOM 1221 O OE1 . GLU A 1 153 ? -1.570 11.820 7.118 1.00 16.93 ? 153 GLU A OE1 1 153 UNP O57413 342 E
ATOM 1222 O OE2 . GLU A 1 153 ? -3.532 11.774 8.024 1.00 18.13 ? 153 GLU A OE2 1 153 UNP O57413 342 E
ATOM 1223 N N . HIS A 1 154 ? 0.912 14.990 5.251 1.00 5.08 ? 154 HIS A N 1 154 UNP O57413 343 H
ATOM 1224 C CA . HIS A 1 154 ? 1.930 15.656 4.457 1.00 3.98 ? 154 HIS A CA 1 154 UNP O57413 343 H
ATOM 1225 C C . HIS A 1 154 ? 1.345 16.624 3.465 1.00 5.54 ? 154 HIS A C 1 154 UNP O57413 343 H
ATOM 1226 O O . HIS A 1 154 ? 0.211 16.433 2.963 1.00 7.30 ? 154 HIS A O 1 154 UNP O57413 343 H
ATOM 1227 C CB . HIS A 1 154 ? 2.766 14.630 3.667 1.00 5.18 ? 154 HIS A CB 1 154 UNP O57413 343 H
ATOM 1228 C CG . HIS A 1 154 ? 3.642 13.803 4.546 1.00 5.36 ? 154 HIS A CG 1 154 UNP O57413 343 H
ATOM 1229 N ND1 . HIS A 1 154 ? 4.165 12.589 4.160 1.00 6.58 ? 154 HIS A ND1 1 154 UNP O57413 343 H
ATOM 1230 C CD2 . HIS A 1 154 ? 4.091 14.025 5.808 1.00 5.25 ? 154 HIS A CD2 1 154 UNP O57413 343 H
ATOM 1231 C CE1 . HIS A 1 154 ? 4.895 12.091 5.147 1.00 5.73 ? 154 HIS A CE1 1 154 UNP O57413 343 H
ATOM 1232 N NE2 . HIS A 1 154 ? 4.862 12.937 6.168 1.00 5.69 ? 154 HIS A NE2 1 154 UNP O57413 343 H
ATOM 1233 N N . ASP A 1 155 ? 2.120 17.654 3.161 1.00 4.35 ? 155 ASP A N 1 155 UNP O57413 344 D
ATOM 1234 C CA . ASP A 1 155 ? 1.733 18.624 2.141 1.00 4.65 ? 155 ASP A CA 1 155 UNP O57413 344 D
ATOM 1235 C C . ASP A 1 155 ? 1.546 17.869 0.816 1.00 5.20 ? 155 ASP A C 1 155 UNP O57413 344 D
ATOM 1236 O O . ASP A 1 155 ? 2.265 16.944 0.497 1.00 5.75 ? 155 ASP A O 1 155 UNP O57413 344 D
ATOM 1237 C CB . ASP A 1 155 ? 2.812 19.707 2.022 1.00 4.82 ? 155 ASP A CB 1 155 UNP O57413 344 D
ATOM 1238 C CG . ASP A 1 155 ? 2.826 20.625 3.221 1.00 4.54 ? 155 ASP A CG 1 155 UNP O57413 344 D
ATOM 1239 O OD1 . ASP A 1 155 ? 1.776 20.757 3.888 1.00 5.57 ? 155 ASP A OD1 1 155 UNP O57413 344 D
ATOM 1240 O OD2 . ASP A 1 155 ? 3.898 21.219 3.460 1.00 5.44 ? 155 ASP A OD2 1 155 UNP O57413 344 D
ATOM 1241 N N . ASP A 1 156 ? 0.575 18.328 0.029 1.00 4.38 ? 156 ASP A N 1 156 UNP O57413 345 D
ATOM 1242 C CA . ASP A 1 156 ? 0.187 17.706 -1.251 1.00 4.93 ? 156 ASP A CA 1 156 UNP O57413 345 D
ATOM 1243 C C . ASP A 1 156 ? 0.047 18.846 -2.257 1.00 5.28 ? 156 ASP A C 1 156 UNP O57413 345 D
ATOM 1244 O O . ASP A 1 156 ? -0.652 19.828 -1.968 1.00 4.92 ? 156 ASP A O 1 156 UNP O57413 345 D
ATOM 1245 C CB . ASP A 1 156 ? -1.140 16.974 -1.013 1.00 6.52 ? 156 ASP A CB 1 156 UNP O57413 345 D
ATOM 1246 C CG . ASP A 1 156 ? -1.724 16.334 -2.297 1.00 8.44 ? 156 ASP A CG 1 156 UNP O57413 345 D
ATOM 1247 O OD1 . ASP A 1 156 ? -2.169 17.069 -3.179 1.00 9.92 ? 156 ASP A OD1 1 156 UNP O57413 345 D
ATOM 1248 O OD2 . ASP A 1 156 ? -1.786 15.101 -2.436 1.00 8.39 ? 156 ASP A OD2 1 156 UNP O57413 345 D
ATOM 1249 N N . LYS A 1 157 ? 0.748 18.724 -3.387 1.00 5.60 ? 157 LYS A N 1 157 UNP O57413 346 K
ATOM 1250 C CA . LYS A 1 157 ? 0.759 19.771 -4.409 1.00 6.04 ? 157 LYS A CA 1 157 UNP O57413 346 K
ATOM 1251 C C . LYS A 1 157 ? -0.601 20.155 -4.966 1.00 6.10 ? 157 LYS A C 1 157 UNP O57413 346 K
ATOM 1252 O O . LYS A 1 157 ? -0.781 21.283 -5.410 1.00 7.94 ? 157 LYS A O 1 157 UNP O57413 346 K
ATOM 1253 C CB . LYS A 1 157 ? 1.706 19.376 -5.546 1.00 8.27 ? 157 LYS A CB 1 157 UNP O57413 346 K
ATOM 1254 C CG . LYS A 1 157 ? 3.156 19.322 -5.146 1.00 11.97 ? 157 LYS A CG 1 157 UNP O57413 346 K
ATOM 1255 C CD . LYS A 1 157 ? 3.577 20.668 -4.565 1.00 15.97 ? 157 LYS A CD 1 157 UNP O57413 346 K
ATOM 1256 C CE . LYS A 1 157 ? 3.453 21.761 -5.585 1.00 18.91 ? 157 LYS A CE 1 157 UNP O57413 346 K
ATOM 1257 N NZ . LYS A 1 157 ? 2.091 21.953 -6.162 1.00 23.30 ? 157 LYS A NZ 1 157 UNP O57413 346 K
ATOM 1258 N N . ASP A 1 158 ? -1.539 19.226 -4.980 1.00 5.57 ? 158 ASP A N 1 158 UNP O57413 347 D
ATOM 1259 C CA . ASP A 1 158 ? -2.876 19.587 -5.447 1.00 7.33 ? 158 ASP A CA 1 158 UNP O57413 347 D
ATOM 1260 C C . ASP A 1 158 ? -3.594 20.487 -4.459 1.00 7.76 ? 158 ASP A C 1 158 UNP O57413 347 D
ATOM 1261 O O . ASP A 1 158 ? -4.455 21.240 -4.855 1.00 8.49 ? 158 ASP A O 1 158 UNP O57413 347 D
ATOM 1262 C CB . ASP A 1 158 ? -3.714 18.346 -5.701 1.00 7.84 ? 158 ASP A CB 1 158 UNP O57413 347 D
ATOM 1263 C CG . ASP A 1 158 ? -3.133 17.479 -6.753 1.00 9.40 ? 158 ASP A CG 1 158 UNP O57413 347 D
ATOM 1264 O OD1 . ASP A 1 158 ? -2.901 18.003 -7.866 1.00 13.22 ? 158 ASP A OD1 1 158 UNP O57413 347 D
ATOM 1265 O OD2 . ASP A 1 158 ? -2.877 16.294 -6.482 1.00 8.93 ? 158 ASP A OD2 1 158 UNP O57413 347 D
ATOM 1266 N N . LYS A 1 159 ? -3.226 20.447 -3.188 1.00 6.85 ? 159 LYS A N 1 159 UNP O57413 348 K
ATOM 1267 C CA . LYS A 1 159 ? -3.876 21.251 -2.155 1.00 6.80 ? 159 LYS A CA 1 159 UNP O57413 348 K
ATOM 1268 C C . LYS A 1 159 ? -3.159 22.534 -1.822 1.00 6.65 ? 159 LYS A C 1 159 UNP O57413 348 K
ATOM 1269 O O . LYS A 1 159 ? -3.816 23.517 -1.472 1.00 8.73 ? 159 LYS A O 1 159 UNP O57413 348 K
ATOM 1270 C CB . LYS A 1 159 ? -4.045 20.399 -0.907 1.00 7.54 ? 159 LYS A CB 1 159 UNP O57413 348 K
ATOM 1271 C CG . LYS A 1 159 ? -5.133 19.356 -1.069 1.00 8.92 ? 159 LYS A CG 1 159 UNP O57413 348 K
ATOM 1272 C CD . LYS A 1 159 ? -5.120 18.323 0.093 1.00 11.35 ? 159 LYS A CD 1 159 UNP O57413 348 K
ATOM 1273 C CE . LYS A 1 159 ? -5.200 18.972 1.472 1.00 14.23 ? 159 LYS A CE 1 159 UNP O57413 348 K
ATOM 1274 N NZ . LYS A 1 159 ? -6.535 19.554 1.825 1.00 17.10 ? 159 LYS A NZ 1 159 UNP O57413 348 K
ATOM 1275 N N . CYS A 1 160 ? -1.839 22.556 -1.903 1.00 5.20 ? 160 CYS A N 1 160 UNP O57413 349 C
ATOM 1276 C CA . CYS A 1 160 ? -1.092 23.791 -1.614 1.00 6.68 ? 160 CYS A CA 1 160 UNP O57413 349 C
ATOM 1277 C C . CYS A 1 160 ? 0.251 23.718 -2.343 1.00 6.52 ? 160 CYS A C 1 160 UNP O57413 349 C
ATOM 1278 O O . CYS A 1 160 ? 0.765 22.654 -2.631 1.00 7.49 ? 160 CYS A O 1 160 UNP O57413 349 C
ATOM 1279 C CB . CYS A 1 160 ? -0.917 23.983 -0.068 1.00 7.23 ? 160 CYS A CB 1 160 UNP O57413 349 C
ATOM 1280 S SG . CYS A 1 160 ? 0.088 22.680 0.718 1.00 9.88 ? 160 CYS A SG 1 160 UNP O57413 349 C
ATOM 1281 N N . LYS A 1 161 ? 0.866 24.860 -2.571 1.00 7.49 ? 161 LYS A N 1 161 UNP O57413 350 K
ATOM 1282 C CA . LYS A 1 161 ? 2.050 24.837 -3.376 1.00 9.38 ? 161 LYS A CA 1 161 UNP O57413 350 K
ATOM 1283 C C . LYS A 1 161 ? 3.406 24.800 -2.669 1.00 8.99 ? 161 LYS A C 1 161 UNP O57413 350 K
ATOM 1284 O O . LYS A 1 161 ? 4.402 24.522 -3.304 1.00 9.80 ? 161 LYS A O 1 161 UNP O57413 350 K
ATOM 1285 C CB . LYS A 1 161 ? 1.936 25.995 -4.369 1.00 11.70 ? 161 LYS A CB 1 161 UNP O57413 350 K
ATOM 1286 C CG . LYS A 1 161 ? 0.663 25.892 -5.294 1.00 12.93 ? 161 LYS A CG 1 161 UNP O57413 350 K
ATOM 1287 C CD . LYS A 1 161 ? 0.469 24.493 -5.979 1.00 14.46 ? 161 LYS A CD 1 161 UNP O57413 350 K
ATOM 1288 C CE . LYS A 1 161 ? -0.785 24.458 -6.894 1.00 15.43 ? 161 LYS A CE 1 161 UNP O57413 350 K
ATOM 1289 N NZ . LYS A 1 161 ? -1.161 23.057 -7.442 1.00 14.61 ? 161 LYS A NZ 1 161 UNP O57413 350 K
ATOM 1290 N N . CYS A 1 162 ? 3.433 25.022 -1.356 1.00 8.79 ? 162 CYS A N 1 162 UNP O57413 351 C
ATOM 1291 C CA . CYS A 1 162 ? 4.724 25.045 -0.659 1.00 9.34 ? 162 CYS A CA 1 162 UNP O57413 351 C
ATOM 1292 C C . CYS A 1 162 ? 5.556 23.797 -0.858 1.00 8.98 ? 162 CYS A C 1 162 UNP O57413 351 C
ATOM 1293 O O . CYS A 1 162 ? 5.038 22.706 -0.726 1.00 10.39 ? 162 CYS A O 1 162 UNP O57413 351 C
ATOM 1294 C CB . CYS A 1 162 ? 4.495 25.250 0.829 1.00 9.22 ? 162 CYS A CB 1 162 UNP O57413 351 C
ATOM 1295 S SG . CYS A 1 162 ? 6.064 25.585 1.679 1.00 9.84 ? 162 CYS A SG 1 162 UNP O57413 351 C
ATOM 1296 N N . THR A 1 163 ? 6.856 23.944 -1.146 1.00 9.81 ? 163 THR A N 1 163 UNP O57413 352 D
ATOM 1297 C CA . THR A 1 163 ? 7.726 22.777 -1.344 1.00 11.75 ? 163 THR A CA 1 163 UNP O57413 352 D
ATOM 1298 C C . THR A 1 163 ? 8.692 22.438 -0.191 1.00 10.81 ? 163 THR A C 1 163 UNP O57413 352 D
ATOM 1299 O O . THR A 1 163 ? 9.242 21.337 -0.155 1.00 13.74 ? 163 THR A O 1 163 UNP O57413 352 D
ATOM 1300 C CB . THR A 1 163 ? 8.602 22.917 -2.602 1.00 13.01 ? 163 THR A CB 1 163 UNP O57413 352 D
ATOM 1301 O OG1 . THR A 1 163 ? 9.302 24.168 -2.543 1.00 16.97 ? 163 THR A OG1 1 163 UNP O57413 352 D
ATOM 1302 C CG2 . THR A 1 163 ? 7.766 22.776 -3.886 1.00 16.07 ? 163 THR A CG2 1 163 UNP O57413 352 D
ATOM 1303 N N . THR A 1 164 ? 8.886 23.371 0.730 1.00 9.05 ? 164 THR A N 1 164 UNP O57413 353 T
ATOM 1304 C CA . THR A 1 164 ? 9.833 23.176 1.835 1.00 8.52 ? 164 THR A CA 1 164 UNP O57413 353 T
ATOM 1305 C C . THR A 1 164 ? 9.226 23.480 3.201 1.00 7.66 ? 164 THR A C 1 164 UNP O57413 353 T
ATOM 1306 O O . THR A 1 164 ? 9.955 23.710 4.198 1.00 7.54 ? 164 THR A O 1 164 UNP O57413 353 T
ATOM 1307 C CB . THR A 1 164 ? 11.097 24.071 1.671 1.00 9.22 ? 164 THR A CB 1 164 UNP O57413 353 T
ATOM 1308 O OG1 . THR A 1 164 ? 10.717 25.452 1.680 1.00 12.37 ? 164 THR A OG1 1 164 UNP O57413 353 T
ATOM 1309 C CG2 . THR A 1 164 ? 11.840 23.742 0.359 1.00 10.35 ? 164 THR A CG2 1 164 UNP O57413 353 T
ATOM 1310 N N . CYS A 1 165 ? 7.905 23.436 3.292 1.00 5.50 ? 165 CYS A N 1 165 UNP O57413 354 C
ATOM 1311 C CA . CYS A 1 165 ? 7.226 23.710 4.553 1.00 4.95 ? 165 CYS A CA 1 165 UNP O57413 354 C
ATOM 1312 C C . CYS A 1 165 ? 7.384 22.540 5.520 1.00 3.98 ? 165 CYS A C 1 165 UNP O57413 354 C
ATOM 1313 O O . CYS A 1 165 ? 7.796 21.455 5.132 1.00 4.60 ? 165 CYS A O 1 165 UNP O57413 354 C
ATOM 1314 C CB . CYS A 1 165 ? 5.768 24.055 4.297 1.00 4.76 ? 165 CYS A CB 1 165 UNP O57413 354 C
ATOM 1315 S SG . CYS A 1 165 ? 5.580 25.756 3.643 1.00 6.83 ? 165 CYS A SG 1 165 UNP O57413 354 C
ATOM 1316 N N . ILE A 1 166 ? 7.040 22.777 6.783 1.00 4.08 ? 166 ILE A N 1 166 UNP O57413 355 I
ATOM 1317 C CA . ILE A 1 166 ? 7.267 21.796 7.823 1.00 3.76 ? 166 ILE A CA 1 166 UNP O57413 355 I
ATOM 1318 C C . ILE A 1 166 ? 6.709 20.407 7.517 1.00 4.34 ? 166 ILE A C 1 166 UNP O57413 355 I
ATOM 1319 O O . ILE A 1 166 ? 7.399 19.448 7.792 1.00 4.15 ? 166 ILE A O 1 166 UNP O57413 355 I
ATOM 1320 C CB . ILE A 1 166 ? 6.680 22.330 9.153 1.00 3.58 ? 166 ILE A CB 1 166 UNP O57413 355 I
ATOM 1321 C CG1 . ILE A 1 166 ? 7.500 23.551 9.613 1.00 4.17 ? 166 ILE A CG1 1 166 UNP O57413 355 I
ATOM 1322 C CG2 . ILE A 1 166 ? 6.725 21.230 10.254 1.00 4.71 ? 166 ILE A CG2 1 166 UNP O57413 355 I
ATOM 1323 C CD1 . ILE A 1 166 ? 6.782 24.401 10.694 1.00 5.21 ? 166 ILE A CD1 1 166 UNP O57413 355 I
ATOM 1324 N N . MET A 1 167 ? 5.501 20.329 6.941 1.00 3.32 ? 167 MET A N 1 167 UNP O57413 356 M
ATOM 1325 C CA . MET A 1 167 ? 4.894 19.027 6.635 1.00 4.46 ? 167 MET A CA 1 167 UNP O57413 356 M
ATOM 1326 C C . MET A 1 167 ? 5.232 18.499 5.249 1.00 4.39 ? 167 MET A C 1 167 UNP O57413 356 M
ATOM 1327 O O . MET A 1 167 ? 4.495 17.662 4.708 1.00 4.68 ? 167 MET A O 1 167 UNP O57413 356 M
ATOM 1328 C CB . MET A 1 167 ? 3.382 19.084 6.847 1.00 3.98 ? 167 MET A CB 1 167 UNP O57413 356 M
ATOM 1329 C CG . MET A 1 167 ? 3.004 19.451 8.311 1.00 4.00 ? 167 MET A CG 1 167 UNP O57413 356 M
ATOM 1330 S SD . MET A 1 167 ? 3.742 18.440 9.605 1.00 4.27 ? 167 MET A SD 1 167 UNP O57413 356 M
ATOM 1331 C CE . MET A 1 167 ? 3.154 16.796 9.137 1.00 6.21 ? 167 MET A CE 1 167 UNP O57413 356 M
ATOM 1332 N N . SER A 1 168 ? 6.354 18.938 4.668 1.00 3.71 ? 168 SER A N 1 168 UNP O57413 357 S
ATOM 1333 C CA . SER A 1 168 ? 6.782 18.367 3.385 1.00 4.11 ? 168 SER A CA 1 168 UNP O57413 357 S
ATOM 1334 C C . SER A 1 168 ? 6.947 16.866 3.589 1.00 5.36 ? 168 SER A C 1 168 UNP O57413 357 S
ATOM 1335 O O . SER A 1 168 ? 7.293 16.389 4.677 1.00 5.14 ? 168 SER A O 1 168 UNP O57413 357 S
ATOM 1336 C CB . SER A 1 168 ? 8.089 19.019 2.919 1.00 4.77 ? 168 SER A CB 1 168 UNP O57413 357 S
ATOM 1337 O OG . SER A 1 168 ? 9.148 18.812 3.837 1.00 7.24 ? 168 SER A OG 1 168 UNP O57413 357 S
ATOM 1338 N N . ALA A 1 169 ? 6.718 16.118 2.511 1.00 6.68 ? 169 ALA A N 1 169 UNP O57413 358 A
ATOM 1339 C CA . ALA A 1 169 ? 6.830 14.673 2.610 1.00 7.31 ? 169 ALA A CA 1 169 UNP O57413 358 A
ATOM 1340 C C . ALA A 1 169 ? 8.220 14.157 3.016 1.00 7.01 ? 169 ALA A C 1 169 UNP O57413 358 A
ATOM 1341 O O . ALA A 1 169 ? 8.333 13.106 3.636 1.00 7.20 ? 169 ALA A O 1 169 UNP O57413 358 A
ATOM 1342 C CB . ALA A 1 169 ? 6.388 14.057 1.275 1.00 7.83 ? 169 ALA A CB 1 169 UNP O57413 358 A
ATOM 1343 N N . VAL A 1 170 ? 9.257 14.897 2.645 1.00 6.21 ? 170 VAL A N 1 170 UNP O57413 359 V
ATOM 1344 C CA . VAL A 1 170 ? 10.635 14.585 2.964 1.00 7.51 ? 170 VAL A CA 1 170 UNP O57413 359 V
ATOM 1345 C C . VAL A 1 170 ? 11.332 15.853 3.422 1.00 6.73 ? 170 VAL A C 1 170 UNP O57413 359 V
ATOM 1346 O O . VAL A 1 170 ? 11.066 16.928 2.912 1.00 7.68 ? 170 VAL A O 1 170 UNP O57413 359 V
ATOM 1347 C CB . VAL A 1 170 ? 11.355 14.052 1.724 1.00 8.04 ? 170 VAL A CB 1 170 UNP O57413 359 V
ATOM 1348 C CG1 . VAL A 1 170 ? 12.686 13.448 2.114 1.00 9.63 ? 170 VAL A CG1 1 170 UNP O57413 359 V
ATOM 1349 C CG2 . VAL A 1 170 ? 10.415 13.094 1.034 1.00 11.17 ? 170 VAL A CG2 1 170 UNP O57413 359 V
ATOM 1350 N N . ILE A 1 171 ? 12.224 15.702 4.390 1.00 5.98 ? 171 ILE A N 1 171 UNP O57413 360 I
ATOM 1351 C CA . ILE A 1 171 ? 13.010 16.815 4.877 1.00 6.34 ? 171 ILE A CA 1 171 UNP O57413 360 I
ATOM 1352 C C . ILE A 1 171 ? 14.107 17.124 3.849 1.00 6.69 ? 171 ILE A C 1 171 UNP O57413 360 I
ATOM 1353 O O . ILE A 1 171 ? 14.488 16.257 3.038 1.00 7.85 ? 171 ILE A O 1 171 UNP O57413 360 I
ATOM 1354 C CB . ILE A 1 171 ? 13.692 16.437 6.263 1.00 5.52 ? 171 ILE A CB 1 171 UNP O57413 360 I
ATOM 1355 C CG1 . ILE A 1 171 ? 14.206 17.690 6.980 1.00 6.02 ? 171 ILE A CG1 1 171 UNP O57413 360 I
ATOM 1356 C CG2 . ILE A 1 171 ? 14.839 15.460 6.052 1.00 7.15 ? 171 ILE A CG2 1 171 UNP O57413 360 I
ATOM 1357 C CD1 . ILE A 1 171 ? 14.687 17.407 8.444 1.00 7.26 ? 171 ILE A CD1 1 171 UNP O57413 360 I
ATOM 1358 N N . SER A 1 172 ? 14.622 18.348 3.875 1.00 6.82 ? 172 SER A N 1 172 UNP O57413 361 S
ATOM 1359 C CA . SER A 1 172 ? 15.771 18.716 3.040 1.00 7.45 ? 172 SER A CA 1 172 UNP O57413 361 S
ATOM 1360 C C . SER A 1 172 ? 16.605 19.769 3.753 1.00 8.24 ? 172 SER A C 1 172 UNP O57413 361 S
ATOM 1361 O O . SER A 1 172 ? 16.191 20.342 4.767 1.00 8.04 ? 172 SER A O 1 172 UNP O57413 361 S
ATOM 1362 C CB . SER A 1 172 ? 15.358 19.252 1.662 1.00 7.65 ? 172 SER A CB 1 172 UNP O57413 361 S
ATOM 1363 O OG . SER A 1 172 ? 14.958 20.614 1.765 1.00 9.67 ? 172 SER A OG 1 172 UNP O57413 361 S
ATOM 1364 N N . ASP A 1 173 ? 17.783 20.034 3.210 1.00 9.85 ? 173 ASP A N 1 173 UNP O57413 362 D
ATOM 1365 C CA . ASP A 1 173 ? 18.663 21.022 3.789 1.00 10.76 ? 173 ASP A CA 1 173 UNP O57413 362 D
ATOM 1366 C C . ASP A 1 173 ? 18.138 22.448 3.617 1.00 10.99 ? 173 ASP A C 1 173 UNP O57413 362 D
ATOM 1367 O O . ASP A 1 173 ? 18.680 23.368 4.199 1.00 13.29 ? 173 ASP A O 1 173 UNP O57413 362 D
ATOM 1368 C CB . ASP A 1 173 ? 20.078 20.841 3.212 1.00 12.55 ? 173 ASP A CB 1 173 UNP O57413 362 D
ATOM 1369 C CG . ASP A 1 173 ? 20.189 21.235 1.756 1.00 14.01 ? 173 ASP A CG 1 173 UNP O57413 362 D
ATOM 1370 O OD1 . ASP A 1 173 ? 19.176 21.310 1.035 1.00 15.66 ? 173 ASP A OD1 1 173 UNP O57413 362 D
ATOM 1371 O OD2 . ASP A 1 173 ? 21.341 21.477 1.303 1.00 17.25 ? 173 ASP A OD2 1 173 UNP O57413 362 D
ATOM 1372 N N . LYS A 1 174 ? 17.057 22.618 2.870 1.00 10.53 ? 174 LYS A N 1 174 UNP O57413 363 K
ATOM 1373 C CA . LYS A 1 174 ? 16.463 23.936 2.681 1.00 11.79 ? 174 LYS A CA 1 174 UNP O57413 363 K
ATOM 1374 C C . LYS A 1 174 ? 15.139 24.015 3.444 1.00 9.92 ? 174 LYS A C 1 174 UNP O57413 363 K
ATOM 1375 O O . LYS A 1 174 ? 14.318 24.873 3.156 1.00 9.83 ? 174 LYS A O 1 174 UNP O57413 363 K
ATOM 1376 C CB . LYS A 1 174 ? 16.203 24.193 1.196 1.00 14.64 ? 174 LYS A CB 1 174 UNP O57413 363 K
ATOM 1377 C CG . LYS A 1 174 ? 17.391 23.904 0.270 1.00 19.49 ? 174 LYS A CG 1 174 UNP O57413 363 K
ATOM 1378 C CD . LYS A 1 174 ? 18.560 24.804 0.597 1.00 21.56 ? 174 LYS A CD 1 174 UNP O57413 363 K
ATOM 1379 C CE . LYS A 1 174 ? 18.945 25.659 -0.613 1.00 23.46 ? 174 LYS A CE 1 174 UNP O57413 363 K
ATOM 1380 N NZ . LYS A 1 174 ? 19.739 26.865 -0.197 1.00 23.87 ? 174 LYS A NZ 1 174 UNP O57413 363 K
ATOM 1381 N N . GLN A 1 175 ? 14.947 23.104 4.399 1.00 8.65 ? 175 GLN A N 1 175 UNP O57413 364 Q
ATOM 1382 C CA . GLN A 1 175 ? 13.696 23.086 5.173 1.00 7.86 ? 175 GLN A CA 1 175 UNP O57413 364 Q
ATOM 1383 C C . GLN A 1 175 ? 13.350 24.467 5.716 1.00 7.76 ? 175 GLN A C 1 175 UNP O57413 364 Q
ATOM 1384 O O . GLN A 1 175 ? 14.201 25.139 6.327 1.00 8.25 ? 175 GLN A O 1 175 UNP O57413 364 Q
ATOM 1385 C CB . GLN A 1 175 ? 13.782 22.095 6.355 1.00 7.11 ? 175 GLN A CB 1 175 UNP O57413 364 Q
ATOM 1386 C CG . GLN A 1 175 ? 12.423 21.602 6.781 1.00 7.07 ? 175 GLN A CG 1 175 UNP O57413 364 Q
ATOM 1387 C CD . GLN A 1 175 ? 11.773 20.752 5.718 1.00 6.43 ? 175 GLN A CD 1 175 UNP O57413 364 Q
ATOM 1388 O OE1 . GLN A 1 175 ? 12.454 20.050 5.008 1.00 7.67 ? 175 GLN A OE1 1 175 UNP O57413 364 Q
ATOM 1389 N NE2 . GLN A 1 175 ? 10.441 20.797 5.620 1.00 8.54 ? 175 GLN A NE2 1 175 UNP O57413 364 Q
ATOM 1390 N N . SER A 1 176 ? 12.111 24.907 5.504 1.00 7.46 ? 176 SER A N 1 176 UNP O57413 365 S
ATOM 1391 C CA . SER A 1 176 ? 11.700 26.197 6.038 1.00 7.78 ? 176 SER A CA 1 176 UNP O57413 365 S
ATOM 1392 C C . SER A 1 176 ? 11.041 25.996 7.406 1.00 7.91 ? 176 SER A C 1 176 UNP O57413 365 S
ATOM 1393 O O . SER A 1 176 ? 10.702 24.866 7.805 1.00 8.84 ? 176 SER A O 1 176 UNP O57413 365 S
ATOM 1394 C CB . SER A 1 176 ? 10.742 26.887 5.070 1.00 11.47 ? 176 SER A CB 1 176 UNP O57413 365 S
ATOM 1395 O OG . SER A 1 176 ? 9.431 26.576 5.377 1.00 12.87 ? 176 SER A OG 1 176 UNP O57413 365 S
ATOM 1396 N N . LYS A 1 177 ? 10.834 27.102 8.107 1.00 6.79 ? 177 LYS A N 1 177 UNP O57413 366 K
ATOM 1397 C CA . LYS A 1 177 ? 10.222 27.055 9.423 1.00 6.84 ? 177 LYS A CA 1 177 UNP O57413 366 K
ATOM 1398 C C . LYS A 1 177 ? 8.729 27.353 9.336 1.00 6.24 ? 177 LYS A C 1 177 UNP O57413 366 K
ATOM 1399 O O . LYS A 1 177 ? 8.096 27.563 10.371 1.00 6.93 ? 177 LYS A O 1 177 UNP O57413 366 K
ATOM 1400 C CB . LYS A 1 177 ? 10.902 28.078 10.328 1.00 8.49 ? 177 LYS A CB 1 177 UNP O57413 366 K
ATOM 1401 C CG . LYS A 1 177 ? 10.638 29.486 9.955 1.00 10.36 ? 177 LYS A CG 1 177 UNP O57413 366 K
ATOM 1402 C CD . LYS A 1 177 ? 11.259 30.353 11.056 1.00 12.45 ? 177 LYS A CD 1 177 UNP O57413 366 K
ATOM 1403 C CE . LYS A 1 177 ? 11.004 31.818 10.831 1.00 13.80 ? 177 LYS A CE 1 177 UNP O57413 366 K
ATOM 1404 N NZ . LYS A 1 177 ? 11.547 32.579 12.031 1.00 11.90 ? 177 LYS A NZ 1 177 UNP O57413 366 K
ATOM 1405 N N . LEU A 1 178 ? 8.166 27.381 8.128 1.00 5.32 ? 178 LEU A N 1 178 UNP O57413 367 L
ATOM 1406 C CA . LEU A 1 178 ? 6.744 27.684 7.943 1.00 5.55 ? 178 LEU A CA 1 178 UNP O57413 367 L
ATOM 1407 C C . LEU A 1 178 ? 5.842 26.486 7.694 1.00 4.92 ? 178 LEU A C 1 178 UNP O57413 367 L
ATOM 1408 O O . LEU A 1 178 ? 6.237 25.490 7.069 1.00 5.13 ? 178 LEU A O 1 178 UNP O57413 367 L
ATOM 1409 C CB . LEU A 1 178 ? 6.551 28.640 6.746 1.00 6.85 ? 178 LEU A CB 1 178 UNP O57413 367 L
ATOM 1410 C CG . LEU A 1 178 ? 7.262 29.983 6.884 1.00 7.82 ? 178 LEU A CG 1 178 UNP O57413 367 L
ATOM 1411 C CD1 . LEU A 1 178 ? 7.048 30.765 5.575 1.00 9.60 ? 178 LEU A CD1 1 178 UNP O57413 367 L
ATOM 1412 C CD2 . LEU A 1 178 ? 6.719 30.758 8.061 1.00 10.77 ? 178 LEU A CD2 1 178 UNP O57413 367 L
ATOM 1413 N N . PHE A 1 179 ? 4.629 26.582 8.229 1.00 4.61 ? 179 PHE A N 1 179 UNP O57413 368 F
ATOM 1414 C CA . PHE A 1 179 ? 3.579 25.602 7.935 1.00 5.50 ? 179 PHE A CA 1 179 UNP O57413 368 F
ATOM 1415 C C . PHE A 1 179 ? 2.907 26.097 6.652 1.00 6.11 ? 179 PHE A C 1 179 UNP O57413 368 F
ATOM 1416 O O . PHE A 1 179 ? 2.638 27.296 6.472 1.00 6.83 ? 179 PHE A O 1 179 UNP O57413 368 F
ATOM 1417 C CB . PHE A 1 179 ? 2.520 25.564 9.043 1.00 5.65 ? 179 PHE A CB 1 179 UNP O57413 368 F
ATOM 1418 C CG . PHE A 1 179 ? 2.921 24.768 10.226 1.00 4.25 ? 179 PHE A CG 1 179 UNP O57413 368 F
ATOM 1419 C CD1 . PHE A 1 179 ? 2.966 23.366 10.155 1.00 5.09 ? 179 PHE A CD1 1 179 UNP O57413 368 F
ATOM 1420 C CD2 . PHE A 1 179 ? 3.287 25.390 11.420 1.00 6.26 ? 179 PHE A CD2 1 179 UNP O57413 368 F
ATOM 1421 C CE1 . PHE A 1 179 ? 3.366 22.605 11.256 1.00 6.19 ? 179 PHE A CE1 1 179 UNP O57413 368 F
ATOM 1422 C CE2 . PHE A 1 179 ? 3.688 24.640 12.509 1.00 6.39 ? 179 PHE A CE2 1 179 UNP O57413 368 F
ATOM 1423 C CZ . PHE A 1 179 ? 3.728 23.257 12.440 1.00 6.98 ? 179 PHE A CZ 1 179 UNP O57413 368 F
ATOM 1424 N N . SER A 1 180 ? 2.615 25.160 5.760 1.00 5.22 ? 180 SER A N 1 180 UNP O57413 369 S
ATOM 1425 C CA . SER A 1 180 ? 1.913 25.450 4.509 1.00 5.23 ? 180 SER A CA 1 180 UNP O57413 369 S
ATOM 1426 C C . SER A 1 180 ? 0.428 25.753 4.753 1.00 5.20 ? 180 SER A C 1 180 UNP O57413 369 S
ATOM 1427 O O . SER A 1 180 ? -0.121 25.558 5.849 1.00 5.27 ? 180 SER A O 1 180 UNP O57413 369 S
ATOM 1428 C CB . SER A 1 180 ? 1.978 24.221 3.628 1.00 4.33 ? 180 SER A CB 1 180 UNP O57413 369 S
ATOM 1429 O OG . SER A 1 180 ? 1.084 23.249 4.157 1.00 4.92 ? 180 SER A OG 1 180 UNP O57413 369 S
ATOM 1430 N N . ASP A 1 181 ? -0.259 26.140 3.678 1.00 5.85 ? 181 ASP A N 1 181 UNP O57413 370 D
ATOM 1431 C CA . ASP A 1 181 ? -1.703 26.357 3.782 1.00 6.34 ? 181 ASP A CA 1 181 UNP O57413 370 D
ATOM 1432 C C . ASP A 1 181 ? -2.385 25.002 3.978 1.00 5.71 ? 181 ASP A C 1 181 UNP O57413 370 D
ATOM 1433 O O . ASP A 1 181 ? -3.418 24.936 4.612 1.00 6.88 ? 181 ASP A O 1 181 UNP O57413 370 D
ATOM 1434 C CB . ASP A 1 181 ? -2.303 26.992 2.513 1.00 9.39 ? 181 ASP A CB 1 181 UNP O57413 370 D
ATOM 1435 C CG . ASP A 1 181 ? -3.844 27.201 2.639 1.00 12.62 ? 181 ASP A CG 1 181 UNP O57413 370 D
ATOM 1436 O OD1 . ASP A 1 181 ? -4.267 27.912 3.590 1.00 17.07 ? 181 ASP A OD1 1 181 UNP O57413 370 D
ATOM 1437 O OD2 . ASP A 1 181 ? -4.635 26.648 1.831 1.00 16.36 ? 181 ASP A OD2 1 181 UNP O57413 370 D
ATOM 1438 N N . CYS A 1 182 ? -1.807 23.919 3.462 1.00 6.02 ? 182 CYS A N 1 182 UNP O57413 371 C
ATOM 1439 C CA . CYS A 1 182 ? -2.399 22.597 3.653 1.00 6.57 ? 182 CYS A CA 1 182 UNP O57413 371 C
ATOM 1440 C C . CYS A 1 182 ? -2.430 22.300 5.163 1.00 5.32 ? 182 CYS A C 1 182 UNP O57413 371 C
ATOM 1441 O O . CYS A 1 182 ? -3.410 21.813 5.707 1.00 5.43 ? 182 CYS A O 1 182 UNP O57413 371 C
ATOM 1442 C CB . CYS A 1 182 ? -1.505 21.507 3.069 1.00 7.75 ? 182 CYS A CB 1 182 UNP O57413 371 C
ATOM 1443 S SG . CYS A 1 182 ? -1.340 21.255 1.261 1.00 11.20 ? 182 CYS A SG 1 182 UNP O57413 371 C
ATOM 1444 N N . SER A 1 183 ? -1.297 22.569 5.817 1.00 4.38 ? 183 SER A N 1 183 UNP O57413 372 S
ATOM 1445 C CA . SER A 1 183 ? -1.151 22.307 7.252 1.00 4.85 ? 183 SER A CA 1 183 UNP O57413 372 S
ATOM 1446 C C . SER A 1 183 ? -2.067 23.160 8.101 1.00 4.84 ? 183 SER A C 1 183 UNP O57413 372 S
ATOM 1447 O O . SER A 1 183 ? -2.691 22.663 9.044 1.00 5.52 ? 183 SER A O 1 183 UNP O57413 372 S
ATOM 1448 C CB . SER A 1 183 ? 0.299 22.582 7.658 1.00 5.41 ? 183 SER A CB 1 183 UNP O57413 372 S
ATOM 1449 O OG . SER A 1 183 ? 1.158 21.637 7.039 1.00 5.06 ? 183 SER A OG 1 183 UNP O57413 372 S
ATOM 1450 N N . LYS A 1 184 ? -2.161 24.447 7.771 1.00 5.13 ? 184 LYS A N 1 184 UNP O57413 373 K
ATOM 1451 C CA . LYS A 1 184 ? -3.038 25.328 8.537 1.00 5.80 ? 184 LYS A CA 1 184 UNP O57413 373 K
ATOM 1452 C C . LYS A 1 184 ? -4.479 24.862 8.365 1.00 6.54 ? 184 LYS A C 1 184 UNP O57413 373 K
ATOM 1453 O O . LYS A 1 184 ? -5.223 24.850 9.328 1.00 7.30 ? 184 LYS A O 1 184 UNP O57413 373 K
ATOM 1454 C CB . LYS A 1 184 ? -2.832 26.776 8.095 1.00 7.08 ? 184 LYS A CB 1 184 UNP O57413 373 K
ATOM 1455 C CG . LYS A 1 184 ? -1.467 27.303 8.484 1.00 7.58 ? 184 LYS A CG 1 184 UNP O57413 373 K
ATOM 1456 C CD . LYS A 1 184 ? -1.298 28.717 7.966 1.00 10.80 ? 184 LYS A CD 1 184 UNP O57413 373 K
ATOM 1457 C CE . LYS A 1 184 ? 0.036 29.221 8.382 1.00 11.88 ? 184 LYS A CE 1 184 UNP O57413 373 K
ATOM 1458 N NZ . LYS A 1 184 ? 0.146 30.648 7.986 1.00 15.78 ? 184 LYS A NZ 1 184 UNP O57413 373 K
ATOM 1459 N N . ASP A 1 185 ? -4.859 24.447 7.150 1.00 6.19 ? 185 ASP A N 1 185 UNP O57413 374 D
ATOM 1460 C CA . ASP A 1 185 ? -6.232 23.969 6.950 1.00 6.79 ? 185 ASP A CA 1 185 UNP O57413 374 D
ATOM 1461 C C . ASP A 1 185 ? -6.472 22.678 7.751 1.00 6.50 ? 185 ASP A C 1 185 UNP O57413 374 D
ATOM 1462 O O . ASP A 1 185 ? -7.545 22.499 8.309 1.00 8.02 ? 185 ASP A O 1 185 UNP O57413 374 D
ATOM 1463 C CB . ASP A 1 185 ? -6.504 23.736 5.462 1.00 7.65 ? 185 ASP A CB 1 185 UNP O57413 374 D
ATOM 1464 C CG . ASP A 1 185 ? -6.612 25.018 4.678 1.00 9.61 ? 185 ASP A CG 1 185 UNP O57413 374 D
ATOM 1465 O OD1 . ASP A 1 185 ? -6.508 26.104 5.264 1.00 10.64 ? 185 ASP A OD1 1 185 UNP O57413 374 D
ATOM 1466 O OD2 . ASP A 1 185 ? -6.785 24.946 3.436 1.00 9.60 ? 185 ASP A OD2 1 185 UNP O57413 374 D
ATOM 1467 N N . TYR A 1 186 ? -5.497 21.761 7.784 1.00 6.08 ? 186 TYR A N 1 186 UNP O57413 375 Y
ATOM 1468 C CA . TYR A 1 186 ? -5.631 20.551 8.600 1.00 6.04 ? 186 TYR A CA 1 186 UNP O57413 375 Y
ATOM 1469 C C . TYR A 1 186 ? -5.826 20.909 10.063 1.00 6.17 ? 186 TYR A C 1 186 UNP O57413 375 Y
ATOM 1470 O O . TYR A 1 186 ? -6.601 20.262 10.760 1.00 7.20 ? 186 TYR A O 1 186 UNP O57413 375 Y
ATOM 1471 C CB . TYR A 1 186 ? -4.390 19.641 8.525 1.00 6.07 ? 186 TYR A CB 1 186 UNP O57413 375 Y
ATOM 1472 C CG . TYR A 1 186 ? -4.336 18.732 7.300 1.00 6.93 ? 186 TYR A CG 1 186 UNP O57413 375 Y
ATOM 1473 C CD1 . TYR A 1 186 ? -3.240 18.759 6.445 1.00 6.86 ? 186 TYR A CD1 1 186 UNP O57413 375 Y
ATOM 1474 C CD2 . TYR A 1 186 ? -5.396 17.848 7.003 1.00 8.07 ? 186 TYR A CD2 1 186 UNP O57413 375 Y
ATOM 1475 C CE1 . TYR A 1 186 ? -3.183 17.946 5.323 1.00 7.02 ? 186 TYR A CE1 1 186 UNP O57413 375 Y
ATOM 1476 C CE2 . TYR A 1 186 ? -5.339 17.036 5.874 1.00 9.06 ? 186 TYR A CE2 1 186 UNP O57413 375 Y
ATOM 1477 C CZ . TYR A 1 186 ? -4.241 17.095 5.049 1.00 7.77 ? 186 TYR A CZ 1 186 UNP O57413 375 Y
ATOM 1478 O OH . TYR A 1 186 ? -4.172 16.337 3.901 1.00 10.67 ? 186 TYR A OH 1 186 UNP O57413 375 Y
ATOM 1479 N N . TYR A 1 187 ? -5.100 21.916 10.544 1.00 6.03 ? 187 TYR A N 1 187 UNP O57413 376 Y
ATOM 1480 C CA . TYR A 1 187 ? -5.232 22.323 11.939 1.00 7.59 ? 187 TYR A CA 1 187 UNP O57413 376 Y
ATOM 1481 C C . TYR A 1 187 ? -6.620 22.894 12.199 1.00 7.83 ? 187 TYR A C 1 187 UNP O57413 376 Y
ATOM 1482 O O . TYR A 1 187 ? -7.203 22.617 13.255 1.00 7.80 ? 187 TYR A O 1 187 UNP O57413 376 Y
ATOM 1483 C CB . TYR A 1 187 ? -4.108 23.314 12.307 1.00 6.34 ? 187 TYR A CB 1 187 UNP O57413 376 Y
ATOM 1484 C CG . TYR A 1 187 ? -4.124 23.712 13.774 1.00 6.03 ? 187 TYR A CG 1 187 UNP O57413 376 Y
ATOM 1485 C CD1 . TYR A 1 187 ? -4.115 22.752 14.780 1.00 6.82 ? 187 TYR A CD1 1 187 UNP O57413 376 Y
ATOM 1486 C CD2 . TYR A 1 187 ? -4.155 25.053 14.134 1.00 6.21 ? 187 TYR A CD2 1 187 UNP O57413 376 Y
ATOM 1487 C CE1 . TYR A 1 187 ? -4.137 23.146 16.132 1.00 7.57 ? 187 TYR A CE1 1 187 UNP O57413 376 Y
ATOM 1488 C CE2 . TYR A 1 187 ? -4.185 25.445 15.462 1.00 7.37 ? 187 TYR A CE2 1 187 UNP O57413 376 Y
ATOM 1489 C CZ . TYR A 1 187 ? -4.173 24.483 16.452 1.00 7.49 ? 187 TYR A CZ 1 187 UNP O57413 376 Y
ATOM 1490 O OH . TYR A 1 187 ? -4.202 24.817 17.803 1.00 7.53 ? 187 TYR A OH 1 187 UNP O57413 376 Y
ATOM 1491 N N . GLN A 1 188 ? -7.156 23.677 11.268 1.00 8.44 ? 188 GLN A N 1 188 UNP O57413 377 Q
ATOM 1492 C CA . GLN A 1 188 ? -8.497 24.206 11.476 1.00 9.41 ? 188 GLN A CA 1 188 UNP O57413 377 Q
ATOM 1493 C C . GLN A 1 188 ? -9.481 23.037 11.583 1.00 10.19 ? 188 GLN A C 1 188 UNP O57413 377 Q
ATOM 1494 O O . GLN A 1 188 ? -10.377 23.041 12.440 1.00 9.87 ? 188 GLN A O 1 188 UNP O57413 377 Q
ATOM 1495 C CB . GLN A 1 188 ? -8.928 25.118 10.322 1.00 10.54 ? 188 GLN A CB 1 188 UNP O57413 377 Q
ATOM 1496 C CG . GLN A 1 188 ? -10.338 25.664 10.560 1.00 12.46 ? 188 GLN A CG 1 188 UNP O57413 377 Q
ATOM 1497 C CD . GLN A 1 188 ? -10.403 26.456 11.862 1.00 13.14 ? 188 GLN A CD 1 188 UNP O57413 377 Q
ATOM 1498 O OE1 . GLN A 1 188 ? -11.024 26.043 12.871 1.00 15.25 ? 188 GLN A OE1 1 188 UNP O57413 377 Q
ATOM 1499 N NE2 . GLN A 1 188 ? -9.751 27.574 11.866 1.00 13.08 ? 188 GLN A NE2 1 188 UNP O57413 377 Q
ATOM 1500 N N . THR A 1 189 ? -9.313 22.030 10.727 1.00 9.79 ? 189 THR A N 1 189 UNP O57413 378 T
ATOM 1501 C CA . THR A 1 189 ? -10.204 20.871 10.747 1.00 9.83 ? 189 THR A CA 1 189 UNP O57413 378 T
ATOM 1502 C C . THR A 1 189 ? -10.132 20.184 12.112 1.00 10.84 ? 189 THR A C 1 189 UNP O57413 378 T
ATOM 1503 O O . THR A 1 189 ? -11.161 19.810 12.701 1.00 11.41 ? 189 THR A O 1 189 UNP O57413 378 T
ATOM 1504 C CB . THR A 1 189 ? -9.816 19.927 9.597 1.00 10.56 ? 189 THR A CB 1 189 UNP O57413 378 T
ATOM 1505 O OG1 . THR A 1 189 ? -10.112 20.585 8.347 1.00 10.12 ? 189 THR A OG1 1 189 UNP O57413 378 T
ATOM 1506 C CG2 . THR A 1 189 ? -10.593 18.617 9.673 1.00 10.76 ? 189 THR A CG2 1 189 UNP O57413 378 T
ATOM 1507 N N . PHE A 1 190 ? -8.910 20.018 12.618 1.00 9.77 ? 190 PHE A N 1 190 UNP O57413 379 F
ATOM 1508 C CA . PHE A 1 190 ? -8.676 19.424 13.926 1.00 10.05 ? 190 PHE A CA 1 190 UNP O57413 379 F
ATOM 1509 C C . PHE A 1 190 ? -9.358 20.209 15.056 1.00 9.92 ? 190 PHE A C 1 190 UNP O57413 379 F
ATOM 1510 O O . PHE A 1 190 ? -10.006 19.597 15.925 1.00 9.52 ? 190 PHE A O 1 190 UNP O57413 379 F
ATOM 1511 C CB . PHE A 1 190 ? -7.163 19.372 14.182 1.00 9.65 ? 190 PHE A CB 1 190 UNP O57413 379 F
ATOM 1512 C CG . PHE A 1 190 ? -6.796 18.625 15.424 1.00 10.91 ? 190 PHE A CG 1 190 UNP O57413 379 F
ATOM 1513 C CD1 . PHE A 1 190 ? -6.985 17.251 15.497 1.00 11.72 ? 190 PHE A CD1 1 190 UNP O57413 379 F
ATOM 1514 C CD2 . PHE A 1 190 ? -6.294 19.300 16.517 1.00 12.38 ? 190 PHE A CD2 1 190 UNP O57413 379 F
ATOM 1515 C CE1 . PHE A 1 190 ? -6.668 16.560 16.662 1.00 12.55 ? 190 PHE A CE1 1 190 UNP O57413 379 F
ATOM 1516 C CE2 . PHE A 1 190 ? -5.976 18.595 17.698 1.00 11.87 ? 190 PHE A CE2 1 190 UNP O57413 379 F
ATOM 1517 C CZ . PHE A 1 190 ? -6.166 17.240 17.754 1.00 11.81 ? 190 PHE A CZ 1 190 UNP O57413 379 F
ATOM 1518 N N . LEU A 1 191 ? -9.219 21.538 15.074 1.00 10.00 ? 191 LEU A N 1 191 UNP O57413 380 L
ATOM 1519 C CA . LEU A 1 191 ? -9.847 22.353 16.122 1.00 10.54 ? 191 LEU A CA 1 191 UNP O57413 380 L
ATOM 1520 C C . LEU A 1 191 ? -11.365 22.292 16.035 1.00 12.26 ? 191 LEU A C 1 191 UNP O57413 380 L
ATOM 1521 O O . LEU A 1 191 ? -12.057 22.386 17.054 1.00 13.04 ? 191 LEU A O 1 191 UNP O57413 380 L
ATOM 1522 C CB . LEU A 1 191 ? -9.412 23.800 15.992 1.00 9.97 ? 191 LEU A CB 1 191 UNP O57413 380 L
ATOM 1523 C CG . LEU A 1 191 ? -7.948 24.075 16.364 1.00 10.30 ? 191 LEU A CG 1 191 UNP O57413 380 L
ATOM 1524 C CD1 . LEU A 1 191 ? -7.738 25.595 16.325 1.00 11.98 ? 191 LEU A CD1 1 191 UNP O57413 380 L
ATOM 1525 C CD2 . LEU A 1 191 ? -7.659 23.534 17.775 1.00 11.37 ? 191 LEU A CD2 1 191 UNP O57413 380 L
ATOM 1526 N N . THR A 1 192 ? -11.868 22.101 14.834 1.00 11.85 ? 192 THR A N 1 192 UNP O57413 381 T
ATOM 1527 C CA . THR A 1 192 ? -13.305 22.025 14.608 1.00 14.45 ? 192 THR A CA 1 192 UNP O57413 381 T
ATOM 1528 C C . THR A 1 192 ? -13.900 20.672 14.944 1.00 14.78 ? 192 THR A C 1 192 UNP O57413 381 T
ATOM 1529 O O . THR A 1 192 ? -14.903 20.593 15.674 1.00 16.15 ? 192 THR A O 1 192 UNP O57413 381 T
ATOM 1530 C CB . THR A 1 192 ? -13.619 22.346 13.160 1.00 14.66 ? 192 THR A CB 1 192 UNP O57413 381 T
ATOM 1531 O OG1 . THR A 1 192 ? -13.308 23.719 12.901 1.00 15.60 ? 192 THR A OG1 1 192 UNP O57413 381 T
ATOM 1532 C CG2 . THR A 1 192 ? -15.114 22.081 12.852 1.00 16.07 ? 192 THR A CG2 1 192 UNP O57413 381 T
ATOM 1533 N N . ASN A 1 193 ? -13.286 19.608 14.440 1.00 14.35 ? 193 ASN A N 1 193 UNP O57413 382 N
ATOM 1534 C CA . ASN A 1 193 ? -13.806 18.254 14.643 1.00 15.07 ? 193 ASN A CA 1 193 UNP O57413 382 N
ATOM 1535 C C . ASN A 1 193 ? -13.394 17.549 15.917 1.00 15.44 ? 193 ASN A C 1 193 UNP O57413 382 N
ATOM 1536 O O . ASN A 1 193 ? -14.159 16.757 16.452 1.00 15.93 ? 193 ASN A O 1 193 UNP O57413 382 N
ATOM 1537 C CB . ASN A 1 193 ? -13.425 17.339 13.467 1.00 15.07 ? 193 ASN A CB 1 193 UNP O57413 382 N
ATOM 1538 C CG . ASN A 1 193 ? -14.020 17.796 12.155 1.00 16.13 ? 193 ASN A CG 1 193 UNP O57413 382 N
ATOM 1539 O OD1 . ASN A 1 193 ? -14.912 18.643 12.135 1.00 18.60 ? 193 ASN A OD1 1 193 UNP O57413 382 N
ATOM 1540 N ND2 . ASN A 1 193 ? -13.524 17.247 11.057 1.00 17.66 ? 193 ASN A ND2 1 193 UNP O57413 382 N
ATOM 1541 N N . ASP A 1 194 ? -12.194 17.831 16.410 1.00 14.78 ? 194 ASP A N 1 194 UNP O57413 383 D
ATOM 1542 C CA . ASP A 1 194 ? -11.655 17.171 17.597 1.00 15.55 ? 194 ASP A CA 1 194 UNP O57413 383 D
ATOM 1543 C C . ASP A 1 194 ? -11.615 18.099 18.809 1.00 14.89 ? 194 ASP A C 1 194 UNP O57413 383 D
ATOM 1544 O O . ASP A 1 194 ? -12.129 17.754 19.871 1.00 15.32 ? 194 ASP A O 1 194 UNP O57413 383 D
ATOM 1545 C CB . ASP A 1 194 ? -10.244 16.617 17.274 1.00 17.33 ? 194 ASP A CB 1 194 UNP O57413 383 D
ATOM 1546 C CG . ASP A 1 194 ? -9.788 15.541 18.252 1.00 20.76 ? 194 ASP A CG 1 194 UNP O57413 383 D
ATOM 1547 O OD1 . ASP A 1 194 ? -9.290 14.482 17.788 1.00 22.61 ? 194 ASP A OD1 1 194 UNP O57413 383 D
ATOM 1548 O OD2 . ASP A 1 194 ? -9.913 15.741 19.480 1.00 21.12 ? 194 ASP A OD2 1 194 UNP O57413 383 D
ATOM 1549 N N . ASN A 1 195 ? -10.975 19.255 18.666 1.00 14.71 ? 195 ASN A N 1 195 UNP O57413 384 N
ATOM 1550 C CA . ASN A 1 195 ? -10.904 20.264 19.726 1.00 14.22 ? 195 ASN A CA 1 195 UNP O57413 384 N
ATOM 1551 C C . ASN A 1 195 ? -10.605 19.656 21.097 1.00 13.58 ? 195 ASN A C 1 195 UNP O57413 384 N
ATOM 1552 O O . ASN A 1 195 ? -11.393 19.817 22.043 1.00 14.68 ? 195 ASN A O 1 195 UNP O57413 384 N
ATOM 1553 C CB . ASN A 1 195 ? -12.246 21.014 19.766 1.00 15.52 ? 195 ASN A CB 1 195 UNP O57413 384 N
ATOM 1554 C CG . ASN A 1 195 ? -12.152 22.346 20.472 1.00 17.25 ? 195 ASN A CG 1 195 UNP O57413 384 N
ATOM 1555 O OD1 . ASN A 1 195 ? -11.070 22.949 20.570 1.00 16.60 ? 195 ASN A OD1 1 195 UNP O57413 384 N
ATOM 1556 N ND2 . ASN A 1 195 ? -13.298 22.845 20.947 1.00 19.07 ? 195 ASN A ND2 1 195 UNP O57413 384 N
ATOM 1557 N N . PRO A 1 196 ? -9.462 18.951 21.236 1.00 12.99 ? 196 PRO A N 1 196 UNP O57413 385 P
ATOM 1558 C CA . PRO A 1 196 ? -9.178 18.365 22.545 1.00 13.02 ? 196 PRO A CA 1 196 UNP O57413 385 P
ATOM 1559 C C . PRO A 1 196 ? -9.038 19.392 23.652 1.00 13.14 ? 196 PRO A C 1 196 UNP O57413 385 P
ATOM 1560 O O . PRO A 1 196 ? -8.498 20.480 23.474 1.00 12.08 ? 196 PRO A O 1 196 UNP O57413 385 P
ATOM 1561 C CB . PRO A 1 196 ? -7.900 17.563 22.300 1.00 14.00 ? 196 PRO A CB 1 196 UNP O57413 385 P
ATOM 1562 C CG . PRO A 1 196 ? -7.209 18.366 21.303 1.00 12.94 ? 196 PRO A CG 1 196 UNP O57413 385 P
ATOM 1563 C CD . PRO A 1 196 ? -8.310 18.768 20.334 1.00 13.73 ? 196 PRO A CD 1 196 UNP O57413 385 P
ATOM 1564 N N . GLN A 1 197 ? -9.561 19.040 24.812 1.00 13.58 ? 197 GLN A N 1 197 UNP O57413 386 Q
ATOM 1565 C CA . GLN A 1 197 ? -9.540 19.958 25.935 1.00 13.94 ? 197 GLN A CA 1 197 UNP O57413 386 Q
ATOM 1566 C C . GLN A 1 197 ? -8.197 20.310 26.556 1.00 12.68 ? 197 GLN A C 1 197 UNP O57413 386 Q
ATOM 1567 O O . GLN A 1 197 ? -8.009 21.430 27.026 1.00 13.07 ? 197 GLN A O 1 197 UNP O57413 386 Q
ATOM 1568 C CB . GLN A 1 197 ? -10.442 19.417 27.046 1.00 16.78 ? 197 GLN A CB 1 197 UNP O57413 386 Q
ATOM 1569 C CG . GLN A 1 197 ? -10.377 20.228 28.348 1.00 21.48 ? 197 GLN A CG 1 197 UNP O57413 386 Q
ATOM 1570 C CD . GLN A 1 197 ? -11.099 21.557 28.267 1.00 24.18 ? 197 GLN A CD 1 197 UNP O57413 386 Q
ATOM 1571 O OE1 . GLN A 1 197 ? -12.237 21.625 27.782 1.00 26.39 ? 197 GLN A OE1 1 197 UNP O57413 386 Q
ATOM 1572 N NE2 . GLN A 1 197 ? -10.456 22.627 28.762 1.00 25.22 ? 197 GLN A NE2 1 197 UNP O57413 386 Q
ATOM 1573 N N . CYS A 1 198 ? -7.243 19.381 26.541 1.00 12.05 ? 198 CYS A N 1 198 UNP O57413 387 C
ATOM 1574 C CA . CYS A 1 198 ? -6.004 19.683 27.235 1.00 12.34 ? 198 CYS A CA 1 198 UNP O57413 387 C
ATOM 1575 C C . CYS A 1 198 ? -5.265 20.885 26.701 1.00 12.34 ? 198 CYS A C 1 198 UNP O57413 387 C
ATOM 1576 O O . CYS A 1 198 ? -4.620 21.582 27.471 1.00 12.93 ? 198 CYS A O 1 198 UNP O57413 387 C
ATOM 1577 C CB . CYS A 1 198 ? -5.085 18.450 27.295 1.00 12.10 ? 198 CYS A CB 1 198 UNP O57413 387 C
ATOM 1578 S SG . CYS A 1 198 ? -3.897 18.124 25.946 1.00 13.77 ? 198 CYS A SG 1 198 UNP O57413 387 C
ATOM 1579 N N . ILE A 1 199 ? -5.403 21.188 25.416 1.00 11.10 ? 199 ILE A N 1 199 UNP O57413 388 I
ATOM 1580 C CA . ILE A 1 199 ? -4.659 22.313 24.862 1.00 11.28 ? 199 ILE A CA 1 199 UNP O57413 388 I
ATOM 1581 C C . ILE A 1 199 ? -5.376 23.656 25.015 1.00 11.27 ? 199 ILE A C 1 199 UNP O57413 388 I
ATOM 1582 O O . ILE A 1 199 ? -4.851 24.691 24.624 1.00 10.24 ? 199 ILE A O 1 199 UNP O57413 388 I
ATOM 1583 C CB . ILE A 1 199 ? -4.221 22.049 23.388 1.00 10.78 ? 199 ILE A CB 1 199 UNP O57413 388 I
ATOM 1584 C CG1 . ILE A 1 199 ? -5.414 21.796 22.479 1.00 11.91 ? 199 ILE A CG1 1 199 UNP O57413 388 I
ATOM 1585 C CG2 . ILE A 1 199 ? -3.269 20.835 23.352 1.00 11.48 ? 199 ILE A CG2 1 199 UNP O57413 388 I
ATOM 1586 C CD1 . ILE A 1 199 ? -5.066 21.876 20.985 1.00 12.44 ? 199 ILE A CD1 1 199 UNP O57413 388 I
ATOM 1587 N N . LEU A 1 200 ? -6.539 23.637 25.664 1.00 12.38 ? 200 LEU A N 1 200 UNP O57413 389 L
ATOM 1588 C CA . LEU A 1 200 ? -7.252 24.877 25.932 1.00 14.43 ? 200 LEU A CA 1 200 UNP O57413 389 L
ATOM 1589 C C . LEU A 1 200 ? -6.746 25.400 27.258 1.00 16.08 ? 200 LEU A C 1 200 UNP O57413 389 L
ATOM 1590 O O . LEU A 1 200 ? -6.955 26.555 27.573 1.00 17.57 ? 200 LEU A O 1 200 UNP O57413 389 L
ATOM 1591 C CB . LEU A 1 200 ? -8.759 24.618 26.035 1.00 15.77 ? 200 LEU A CB 1 200 UNP O57413 389 L
ATOM 1592 C CG . LEU A 1 200 ? -9.492 24.617 24.694 1.00 17.06 ? 200 LEU A CG 1 200 UNP O57413 389 L
ATOM 1593 C CD1 . LEU A 1 200 ? -9.622 26.036 24.198 1.00 18.67 ? 200 LEU A CD1 1 200 UNP O57413 389 L
ATOM 1594 C CD2 . LEU A 1 200 ? -8.761 23.768 23.709 1.00 20.06 ? 200 LEU A CD2 1 200 UNP O57413 389 L
ATOM 1595 N N . ASN A 1 201 ? -6.055 24.541 28.007 1.00 17.24 ? 201 ASN A N 1 201 UNP O57413 390 N
ATOM 1596 C CA . ASN A 1 201 ? -5.549 24.889 29.324 1.00 18.51 ? 201 ASN A CA 1 201 UNP O57413 390 N
ATOM 1597 C C . ASN A 1 201 ? -4.168 25.535 29.377 1.00 17.75 ? 201 ASN A C 1 201 UNP O57413 390 N
ATOM 1598 O O . ASN A 1 201 ? -3.165 24.921 29.011 1.00 18.62 ? 201 ASN A O 1 201 UNP O57413 390 N
ATOM 1599 C CB . ASN A 1 201 ? -5.532 23.651 30.228 1.00 20.54 ? 201 ASN A CB 1 201 UNP O57413 390 N
ATOM 1600 C CG . ASN A 1 201 ? -6.869 22.942 30.287 1.00 22.04 ? 201 ASN A CG 1 201 UNP O57413 390 N
ATOM 1601 O OD1 . ASN A 1 201 ? -7.931 23.570 30.251 1.00 23.52 ? 201 ASN A OD1 1 201 UNP O57413 390 N
ATOM 1602 N ND2 . ASN A 1 201 ? -6.826 21.623 30.406 1.00 22.77 ? 201 ASN A ND2 1 201 UNP O57413 390 N
ATOM 1603 N N . ALA A 1 202 ? -4.114 26.773 29.842 1.00 17.76 ? 202 ALA A N 1 202 UNP O57413 391 A
ATOM 1604 C CA . ALA A 1 202 ? -2.834 27.456 29.991 1.00 17.08 ? 202 ALA A CA 1 202 UNP O57413 391 A
ATOM 1605 C C . ALA A 1 202 ? -2.150 26.833 31.219 1.00 16.75 ? 202 ALA A C 1 202 UNP O57413 391 A
ATOM 1606 O O . ALA A 1 202 ? -2.828 26.358 32.134 1.00 17.82 ? 202 ALA A O 1 202 UNP O57413 391 A
ATOM 1607 C CB . ALA A 1 202 ? -3.056 28.935 30.227 1.00 17.58 ? 202 ALA A CB 1 202 UNP O57413 391 A
ATOM 1608 N N . PRO A 1 203 ? -0.811 26.811 31.257 1.00 15.27 ? 203 PRO A N 1 203 UNP O57413 392 P
ATOM 1609 C CA . PRO A 1 203 ? -0.092 26.233 32.404 1.00 15.89 ? 203 PRO A CA 1 203 UNP O57413 392 P
ATOM 1610 C C . PRO A 1 203 ? -0.439 26.974 33.699 1.00 17.34 ? 203 PRO A C 1 203 UNP O57413 392 P
ATOM 1611 O O . PRO A 1 203 ? -0.748 28.172 33.639 1.00 17.89 ? 203 PRO A O 1 203 UNP O57413 392 P
ATOM 1612 C CB . PRO A 1 203 ? 1.375 26.423 32.029 1.00 15.81 ? 203 PRO A CB 1 203 UNP O57413 392 P
ATOM 1613 C CG . PRO A 1 203 ? 1.365 26.401 30.503 1.00 14.61 ? 203 PRO A CG 1 203 UNP O57413 392 P
ATOM 1614 C CD . PRO A 1 203 ? 0.116 27.207 30.176 1.00 15.40 ? 203 PRO A CD 1 203 UNP O57413 392 P
ATOM 1615 O OXT . PRO A 1 203 ? -0.355 26.351 34.772 1.00 16.93 ? 203 PRO A OXT 1 203 UNP O57413 392 P
HETATM 1616 N N . PCA B 2 1 ? 14.734 9.722 3.561 1.00 15.64 ? 251 PCA B N 1 1 ? ? ? ?
HETATM 1617 C CA . PCA B 2 1 ? 14.531 9.796 5.017 1.00 13.22 ? 251 PCA B CA 1 1 ? ? ? ?
HETATM 1618 C CB . PCA B 2 1 ? 15.157 11.083 5.544 1.00 15.39 ? 251 PCA B CB 1 1 ? ? ? ?
HETATM 1619 C CG . PCA B 2 1 ? 15.572 11.809 4.311 1.00 15.97 ? 251 PCA B CG 1 1 ? ? ? ?
HETATM 1620 C CD . PCA B 2 1 ? 15.240 10.889 3.172 1.00 16.08 ? 251 PCA B CD 1 1 ? ? ? ?
HETATM 1621 O OE . PCA B 2 1 ? 15.420 11.182 1.994 1.00 16.73 ? 251 PCA B OE 1 1 ? ? ? ?
HETATM 1622 C C . PCA B 2 1 ? 13.033 9.810 5.258 1.00 12.54 ? 251 PCA B C 1 1 ? ? ? ?
HETATM 1623 O O . PCA B 2 1 ? 12.295 10.584 4.639 1.00 12.05 ? 251 PCA B O 1 1 ? ? ? ?
ATOM 1624 N N . ASN B 2 2 ? 12.569 8.957 6.158 1.00 9.77 ? 252 ASN B N 1 2 ? ? ? ?
ATOM 1625 C CA . ASN B 2 2 ? 11.147 8.896 6.452 1.00 9.06 ? 252 ASN B CA 1 2 ? ? ? ?
ATOM 1626 C C . ASN B 2 2 ? 10.890 9.684 7.729 1.00 7.91 ? 252 ASN B C 1 2 ? ? ? ?
ATOM 1627 O O . ASN B 2 2 ? 11.633 9.558 8.692 1.00 8.28 ? 252 ASN B O 1 2 ? ? ? ?
ATOM 1628 C CB . ASN B 2 2 ? 10.699 7.448 6.707 1.00 9.21 ? 252 ASN B CB 1 2 ? ? ? ?
ATOM 1629 C CG . ASN B 2 2 ? 10.382 6.690 5.425 1.00 11.24 ? 252 ASN B CG 1 2 ? ? ? ?
ATOM 1630 O OD1 . ASN B 2 2 ? 9.514 7.094 4.643 1.00 12.87 ? 252 ASN B OD1 1 2 ? ? ? ?
ATOM 1631 N ND2 . ASN B 2 2 ? 11.082 5.578 5.210 1.00 12.25 ? 252 ASN B ND2 1 2 ? ? ? ?
ATOM 1632 N N . TRP B 2 3 ? 9.848 10.506 7.709 1.00 6.65 ? 253 TRP B N 1 3 ? ? ? ?
ATOM 1633 C CA . TRP B 2 3 ? 9.428 11.272 8.882 1.00 5.48 ? 253 TRP B CA 1 3 ? ? ? ?
ATOM 1634 C C . TRP B 2 3 ? 7.945 11.541 8.792 1.00 6.10 ? 253 TRP B C 1 3 ? ? ? ?
ATOM 1635 O O . TRP B 2 3 ? 7.318 11.929 9.786 1.00 6.35 ? 253 TRP B O 1 3 ? ? ? ?
ATOM 1636 C CB . TRP B 2 3 ? 10.199 12.586 9.017 1.00 5.11 ? 253 TRP B CB 1 3 ? ? ? ?
ATOM 1637 C CG . TRP B 2 3 ? 9.899 13.717 8.013 1.00 4.35 ? 253 TRP B CG 1 3 ? ? ? ?
ATOM 1638 C CD1 . TRP B 2 3 ? 9.256 13.647 6.800 1.00 4.41 ? 253 TRP B CD1 1 3 ? ? ? ?
ATOM 1639 C CD2 . TRP B 2 3 ? 10.240 15.084 8.204 1.00 3.66 ? 253 TRP B CD2 1 3 ? ? ? ?
ATOM 1640 N NE1 . TRP B 2 3 ? 9.180 14.905 6.225 1.00 5.11 ? 253 TRP B NE1 1 3 ? ? ? ?
ATOM 1641 C CE2 . TRP B 2 3 ? 9.773 15.810 7.065 1.00 3.95 ? 253 TRP B CE2 1 3 ? ? ? ?
ATOM 1642 C CE3 . TRP B 2 3 ? 10.886 15.775 9.218 1.00 4.21 ? 253 TRP B CE3 1 3 ? ? ? ?
ATOM 1643 C CZ2 . TRP B 2 3 ? 9.936 17.198 6.936 1.00 4.38 ? 253 TRP B CZ2 1 3 ? ? ? ?
ATOM 1644 C CZ3 . TRP B 2 3 ? 11.063 17.155 9.099 1.00 4.62 ? 253 TRP B CZ3 1 3 ? ? ? ?
ATOM 1645 C CH2 . TRP B 2 3 ? 10.591 17.857 7.971 1.00 4.54 ? 253 TRP B CH2 1 3 ? ? ? ?
ATOM 1646 O OXT . TRP B 2 3 ? 7.374 11.384 7.691 1.00 6.66 ? 253 TRP B OXT 1 3 ? ? ? ?
HETATM 1647 CD CD . CD C 3 . ? 5.554 12.624 8.212 1.00 6.68 ? 981 CD A CD 1 981 ? ? ? ?
HETATM 1648 CD CD . CD D 3 . ? 15.466 28.026 28.239 1.00 9.01 ? 982 CD A CD 1 982 ? ? ? ?
HETATM 1649 CD CD . CD E 3 . ? -6.631 27.175 2.810 1.00 15.89 ? 983 CD A CD 1 983 ? ? ? ?
HETATM 1650 CD CD . CD F 3 . ? 25.592 3.636 30.178 1.00 43.42 ? 984 CD A CD 1 984 ? ? ? ?
HETATM 1651 CD CD . CD G 3 . ? -1.280 34.121 21.325 1.00 19.71 ? 985 CD A CD 1 985 ? ? ? ?
HETATM 1652 CD CD . CD H 3 . ? -8.897 13.826 20.002 1.00 49.46 ? 986 CD A CD 1 986 ? ? ? ?
HETATM 1653 CD CD . CD I 3 . ? -0.782 28.393 35.956 1.00 25.41 ? 987 CD A CD 1 987 ? ? ? ?
HETATM 1654 CD CD . CD J 3 . ? 19.743 14.230 9.381 1.00 12.60 ? 988 CD A CD 1 988 ? ? ? ?
HETATM 1655 CD CD . CD K 3 . ? 0.333 28.604 -0.122 1.00 19.95 ? 989 CD A CD 1 989 ? ? ? ?
HETATM 1656 CD CD . CD L 3 . ? -2.524 2.550 32.844 0.50 11.19 ? 990 CD A CD 1 990 ? ? ? ?
HETATM 1657 CD CD . CD M 3 . ? -5.559 5.804 31.495 1.00 33.86 ? 991 CD A CD 1 991 ? ? ? ?
HETATM 1658 O O . HOH N 4 . ? 22.690 24.171 15.324 1.00 13.30 ? 301 HOH A O 1 301 ? ? ? ?
HETATM 1659 O O . HOH N 4 . ? 20.528 24.710 13.799 1.00 8.33 ? 302 HOH A O 1 302 ? ? ? ?
HETATM 1660 O O . HOH N 4 . ? 20.866 25.359 10.871 1.00 19.07 ? 303 HOH A O 1 303 ? ? ? ?
HETATM 1661 O O . HOH N 4 . ? 12.154 -3.215 16.093 1.00 7.81 ? 304 HOH A O 1 304 ? ? ? ?
HETATM 1662 O O . HOH N 4 . ? 11.333 2.782 11.665 1.00 10.15 ? 305 HOH A O 1 305 ? ? ? ?
HETATM 1663 O O . HOH N 4 . ? 12.622 29.278 7.009 1.00 16.86 ? 306 HOH A O 1 306 ? ? ? ?
HETATM 1664 O O . HOH N 4 . ? 14.065 31.015 7.954 1.00 18.09 ? 307 HOH A O 1 307 ? ? ? ?
HETATM 1665 O O . HOH N 4 . ? 10.250 32.199 6.506 1.00 25.43 ? 308 HOH A O 1 308 ? ? ? ?
HETATM 1666 O O . HOH N 4 . ? 10.409 -0.104 10.216 1.00 24.18 ? 309 HOH A O 1 309 ? ? ? ?
HETATM 1667 O O . HOH N 4 . ? 13.991 -2.451 8.438 1.00 17.93 ? 310 HOH A O 1 310 ? ? ? ?
HETATM 1668 O O . HOH N 4 . ? 16.716 0.032 7.780 1.00 10.21 ? 311 HOH A O 1 311 ? ? ? ?
HETATM 1669 O O . HOH N 4 . ? 8.891 16.195 -0.219 1.00 14.63 ? 312 HOH A O 1 312 ? ? ? ?
HETATM 1670 O O . HOH N 4 . ? 19.872 0.417 12.283 1.00 8.89 ? 313 HOH A O 1 313 ? ? ? ?
HETATM 1671 O O . HOH N 4 . ? 4.140 30.037 19.672 1.00 11.16 ? 314 HOH A O 1 314 ? ? ? ?
HETATM 1672 O O . HOH N 4 . ? -10.787 29.128 22.055 1.00 25.48 ? 315 HOH A O 1 315 ? ? ? ?
HETATM 1673 O O . HOH N 4 . ? 5.906 33.355 20.745 1.00 23.86 ? 316 HOH A O 1 316 ? ? ? ?
HETATM 1674 O O . HOH N 4 . ? 1.721 31.736 19.435 1.00 27.42 ? 317 HOH A O 1 317 ? ? ? ?
HETATM 1675 O O . HOH N 4 . ? -8.529 22.280 21.273 1.00 11.08 ? 318 HOH A O 1 318 ? ? ? ?
HETATM 1676 O O . HOH N 4 . ? -3.381 35.540 20.956 1.00 13.48 ? 319 HOH A O 1 319 ? ? ? ?
HETATM 1677 O O . HOH N 4 . ? 0.571 32.388 21.659 1.00 18.35 ? 320 HOH A O 1 320 ? ? ? ?
HETATM 1678 O O . HOH N 4 . ? 20.343 -1.776 8.824 1.00 12.87 ? 321 HOH A O 1 321 ? ? ? ?
HETATM 1679 O O . HOH N 4 . ? 2.211 28.991 27.937 1.00 15.84 ? 322 HOH A O 1 322 ? ? ? ?
HETATM 1680 O O . HOH N 4 . ? -7.345 7.100 24.853 1.00 20.14 ? 323 HOH A O 1 323 ? ? ? ?
HETATM 1681 O O . HOH N 4 . ? -2.129 13.332 27.706 1.00 12.57 ? 324 HOH A O 1 324 ? ? ? ?
HETATM 1682 O O . HOH N 4 . ? 3.870 22.678 33.443 1.00 8.82 ? 325 HOH A O 1 325 ? ? ? ?
HETATM 1683 O O . HOH N 4 . ? 14.247 22.049 32.059 1.00 12.33 ? 326 HOH A O 1 326 ? ? ? ?
HETATM 1684 O O . HOH N 4 . ? 24.370 4.146 25.870 1.00 23.25 ? 327 HOH A O 1 327 ? ? ? ?
HETATM 1685 O O . HOH N 4 . ? 17.752 6.135 33.401 1.00 17.25 ? 328 HOH A O 1 328 ? ? ? ?
HETATM 1686 O O . HOH N 4 . ? 12.586 11.969 39.939 1.00 47.48 ? 329 HOH A O 1 329 ? ? ? ?
HETATM 1687 O O . HOH N 4 . ? 27.425 7.766 31.720 1.00 44.42 ? 330 HOH A O 1 330 ? ? ? ?
HETATM 1688 O O . HOH N 4 . ? 19.107 4.387 24.116 1.00 14.08 ? 331 HOH A O 1 331 ? ? ? ?
HETATM 1689 O O . HOH N 4 . ? 20.199 4.190 21.790 1.00 25.47 ? 332 HOH A O 1 332 ? ? ? ?
HETATM 1690 O O . HOH N 4 . ? 29.441 9.588 27.518 1.00 30.23 ? 333 HOH A O 1 333 ? ? ? ?
HETATM 1691 O O . HOH N 4 . ? -0.496 13.967 38.422 1.00 41.40 ? 334 HOH A O 1 334 ? ? ? ?
HETATM 1692 O O . HOH N 4 . ? 1.166 18.022 37.314 1.00 16.04 ? 335 HOH A O 1 335 ? ? ? ?
HETATM 1693 O O . HOH N 4 . ? 2.954 18.688 39.467 1.00 19.45 ? 336 HOH A O 1 336 ? ? ? ?
HETATM 1694 O O . HOH N 4 . ? 5.642 16.794 42.826 1.00 35.94 ? 337 HOH A O 1 337 ? ? ? ?
HETATM 1695 O O . HOH N 4 . ? 4.995 17.070 39.592 1.00 21.35 ? 338 HOH A O 1 338 ? ? ? ?
HETATM 1696 O O . HOH N 4 . ? 1.311 10.312 43.869 1.00 44.35 ? 339 HOH A O 1 339 ? ? ? ?
HETATM 1697 O O . HOH N 4 . ? -2.886 17.356 29.881 1.00 22.87 ? 340 HOH A O 1 340 ? ? ? ?
HETATM 1698 O O . HOH N 4 . ? -2.133 22.145 28.852 1.00 18.43 ? 341 HOH A O 1 341 ? ? ? ?
HETATM 1699 O O . HOH N 4 . ? -4.522 20.222 30.914 1.00 30.67 ? 342 HOH A O 1 342 ? ? ? ?
HETATM 1700 O O . HOH N 4 . ? 29.066 4.021 21.227 1.00 28.02 ? 343 HOH A O 1 343 ? ? ? ?
HETATM 1701 O O . HOH N 4 . ? 23.217 11.420 7.540 1.00 38.53 ? 344 HOH A O 1 344 ? ? ? ?
HETATM 1702 O O . HOH N 4 . ? 17.449 6.298 10.984 1.00 8.48 ? 345 HOH A O 1 345 ? ? ? ?
HETATM 1703 O O . HOH N 4 . ? 17.788 2.814 8.667 1.00 10.49 ? 346 HOH A O 1 346 ? ? ? ?
HETATM 1704 O O . HOH N 4 . ? -8.088 16.409 26.613 1.00 18.55 ? 347 HOH A O 1 347 ? ? ? ?
HETATM 1705 O O . HOH N 4 . ? 17.759 28.191 27.510 1.00 5.29 ? 348 HOH A O 1 348 ? ? ? ?
HETATM 1706 O O . HOH N 4 . ? 14.783 30.168 27.510 1.00 15.41 ? 349 HOH A O 1 349 ? ? ? ?
HETATM 1707 O O . HOH N 4 . ? 11.153 21.774 32.318 1.00 24.61 ? 350 HOH A O 1 350 ? ? ? ?
HETATM 1708 O O . HOH N 4 . ? 11.619 19.008 34.186 1.00 18.30 ? 351 HOH A O 1 351 ? ? ? ?
HETATM 1709 O O . HOH N 4 . ? 24.143 21.868 24.405 1.00 17.47 ? 352 HOH A O 1 352 ? ? ? ?
HETATM 1710 O O . HOH N 4 . ? 21.480 16.875 7.208 1.00 8.17 ? 353 HOH A O 1 353 ? ? ? ?
HETATM 1711 O O . HOH N 4 . ? 19.658 11.879 9.189 1.00 16.82 ? 354 HOH A O 1 354 ? ? ? ?
HETATM 1712 O O . HOH N 4 . ? 19.344 16.613 8.567 1.00 8.81 ? 355 HOH A O 1 355 ? ? ? ?
HETATM 1713 O O . HOH N 4 . ? 18.594 13.292 7.542 1.00 24.37 ? 356 HOH A O 1 356 ? ? ? ?
HETATM 1714 O O . HOH N 4 . ? 8.961 2.844 10.002 1.00 35.13 ? 357 HOH A O 1 357 ? ? ? ?
HETATM 1715 O O . HOH N 4 . ? 5.987 21.639 1.718 1.00 7.72 ? 358 HOH A O 1 358 ? ? ? ?
HETATM 1716 O O . HOH N 4 . ? 6.460 19.518 -0.171 1.00 15.14 ? 359 HOH A O 1 359 ? ? ? ?
HETATM 1717 O O . HOH N 4 . ? -6.982 17.553 10.369 1.00 11.29 ? 360 HOH A O 1 360 ? ? ? ?
HETATM 1718 O O . HOH N 4 . ? -8.763 16.269 12.217 1.00 17.33 ? 361 HOH A O 1 361 ? ? ? ?
HETATM 1719 O O . HOH N 4 . ? -2.163 17.689 2.105 1.00 14.51 ? 362 HOH A O 1 362 ? ? ? ?
HETATM 1720 O O . HOH N 4 . ? 2.001 14.213 -0.011 1.00 16.98 ? 363 HOH A O 1 363 ? ? ? ?
HETATM 1721 O O . HOH N 4 . ? 0.352 11.581 2.913 1.00 40.26 ? 364 HOH A O 1 364 ? ? ? ?
HETATM 1722 O O . HOH N 4 . ? 0.081 19.583 5.678 1.00 6.49 ? 365 HOH A O 1 365 ? ? ? ?
HETATM 1723 O O . HOH N 4 . ? 0.761 12.102 5.671 1.00 13.58 ? 366 HOH A O 1 366 ? ? ? ?
HETATM 1724 O O . HOH N 4 . ? -4.167 9.523 8.928 1.00 30.03 ? 367 HOH A O 1 367 ? ? ? ?
HETATM 1725 O O . HOH N 4 . ? 3.562 22.370 6.010 1.00 4.19 ? 368 HOH A O 1 368 ? ? ? ?
HETATM 1726 O O . HOH N 4 . ? 5.057 17.161 0.398 1.00 10.69 ? 369 HOH A O 1 369 ? ? ? ?
HETATM 1727 O O . HOH N 4 . ? 2.211 15.912 -3.825 1.00 2.75 ? 370 HOH A O 1 370 ? ? ? ?
HETATM 1728 O O . HOH N 4 . ? -8.068 17.132 2.853 1.00 20.29 ? 371 HOH A O 1 371 ? ? ? ?
HETATM 1729 O O . HOH N 4 . ? -9.016 17.560 5.709 1.00 25.12 ? 372 HOH A O 1 372 ? ? ? ?
HETATM 1730 O O . HOH N 4 . ? -12.917 11.478 9.267 1.00 46.58 ? 373 HOH A O 1 373 ? ? ? ?
HETATM 1731 O O . HOH N 4 . ? -5.715 20.594 4.412 1.00 12.49 ? 374 HOH A O 1 374 ? ? ? ?
HETATM 1732 O O . HOH N 4 . ? 2.737 21.124 -1.132 1.00 11.23 ? 375 HOH A O 1 375 ? ? ? ?
HETATM 1733 O O . HOH N 4 . ? 8.967 27.732 -4.045 1.00 36.52 ? 376 HOH A O 1 376 ? ? ? ?
HETATM 1734 O O . HOH N 4 . ? 9.682 19.072 -3.587 1.00 38.25 ? 377 HOH A O 1 377 ? ? ? ?
HETATM 1735 O O . HOH N 4 . ? 4.185 -1.665 26.889 1.00 20.61 ? 378 HOH A O 1 378 ? ? ? ?
HETATM 1736 O O . HOH N 4 . ? 4.877 0.702 30.172 1.00 18.09 ? 379 HOH A O 1 379 ? ? ? ?
HETATM 1737 O O . HOH N 4 . ? -1.106 27.318 -1.837 1.00 7.68 ? 380 HOH A O 1 380 ? ? ? ?
HETATM 1738 O O . HOH N 4 . ? 13.084 17.170 -1.154 1.00 17.74 ? 381 HOH A O 1 381 ? ? ? ?
HETATM 1739 O O . HOH N 4 . ? 2.915 35.991 16.367 1.00 40.26 ? 382 HOH A O 1 382 ? ? ? ?
HETATM 1740 O O . HOH N 4 . ? 5.922 28.807 11.433 1.00 8.51 ? 383 HOH A O 1 383 ? ? ? ?
HETATM 1741 O O . HOH N 4 . ? 3.734 28.776 9.710 1.00 8.13 ? 384 HOH A O 1 384 ? ? ? ?
HETATM 1742 O O . HOH N 4 . ? 2.997 31.201 8.399 1.00 13.60 ? 385 HOH A O 1 385 ? ? ? ?
HETATM 1743 O O . HOH N 4 . ? 1.285 26.699 0.830 1.00 1.00 ? 386 HOH A O 1 386 ? ? ? ?
HETATM 1744 O O . HOH N 4 . ? 12.370 20.619 2.372 1.00 11.37 ? 387 HOH A O 1 387 ? ? ? ?
HETATM 1745 O O . HOH N 4 . ? 3.323 29.049 4.350 1.00 15.03 ? 388 HOH A O 1 388 ? ? ? ?
HETATM 1746 O O . HOH N 4 . ? -9.843 23.636 6.867 1.00 16.62 ? 389 HOH A O 1 389 ? ? ? ?
HETATM 1747 O O . HOH N 4 . ? -9.867 21.902 4.466 1.00 24.07 ? 390 HOH A O 1 390 ? ? ? ?
HETATM 1748 O O . HOH N 4 . ? -4.635 23.921 1.439 1.00 26.52 ? 391 HOH A O 1 391 ? ? ? ?
HETATM 1749 O O . HOH N 4 . ? -3.234 31.767 5.776 1.00 29.07 ? 392 HOH A O 1 392 ? ? ? ?
HETATM 1750 O O . HOH N 4 . ? -10.642 14.761 8.912 1.00 29.39 ? 393 HOH A O 1 393 ? ? ? ?
HETATM 1751 O O . HOH N 4 . ? -11.322 15.425 11.529 1.00 23.62 ? 394 HOH A O 1 394 ? ? ? ?
HETATM 1752 O O . HOH N 4 . ? -9.664 29.586 13.689 1.00 23.68 ? 395 HOH A O 1 395 ? ? ? ?
HETATM 1753 O O . HOH N 4 . ? -8.861 28.673 9.737 1.00 18.99 ? 396 HOH A O 1 396 ? ? ? ?
HETATM 1754 O O . HOH N 4 . ? -12.771 29.449 19.347 1.00 38.10 ? 397 HOH A O 1 397 ? ? ? ?
HETATM 1755 O O . HOH N 4 . ? -15.412 14.746 22.936 1.00 46.51 ? 398 HOH A O 1 398 ? ? ? ?
HETATM 1756 O O . HOH N 4 . ? -12.983 25.086 17.498 1.00 32.68 ? 399 HOH A O 1 399 ? ? ? ?
HETATM 1757 O O . HOH N 4 . ? 0.921 39.116 17.860 1.00 39.93 ? 400 HOH A O 1 400 ? ? ? ?
HETATM 1758 O O . HOH N 4 . ? -2.793 34.751 11.688 1.00 26.83 ? 401 HOH A O 1 401 ? ? ? ?
HETATM 1759 O O . HOH N 4 . ? -10.305 33.481 17.009 1.00 41.12 ? 402 HOH A O 1 402 ? ? ? ?
HETATM 1760 O O . HOH N 4 . ? -11.981 27.255 15.772 1.00 29.40 ? 403 HOH A O 1 403 ? ? ? ?
HETATM 1761 O O . HOH N 4 . ? -7.909 33.360 21.442 1.00 21.09 ? 404 HOH A O 1 404 ? ? ? ?
HETATM 1762 O O . HOH N 4 . ? 2.118 26.354 27.072 1.00 8.82 ? 405 HOH A O 1 405 ? ? ? ?
HETATM 1763 O O . HOH N 4 . ? 4.293 24.216 30.951 1.00 18.32 ? 406 HOH A O 1 406 ? ? ? ?
HETATM 1764 O O . HOH N 4 . ? 4.534 26.803 32.150 1.00 16.02 ? 407 HOH A O 1 407 ? ? ? ?
HETATM 1765 O O . HOH N 4 . ? 16.111 13.632 34.395 1.00 19.24 ? 408 HOH A O 1 408 ? ? ? ?
HETATM 1766 O O . HOH N 4 . ? 25.094 6.567 22.219 1.00 13.59 ? 409 HOH A O 1 409 ? ? ? ?
HETATM 1767 O O . HOH N 4 . ? 22.158 10.815 12.704 1.00 27.06 ? 410 HOH A O 1 410 ? ? ? ?
HETATM 1768 O O . HOH N 4 . ? 20.275 1.507 28.857 1.00 23.31 ? 411 HOH A O 1 411 ? ? ? ?
HETATM 1769 O O . HOH N 4 . ? 15.671 16.391 -1.238 1.00 15.90 ? 414 HOH A O 1 414 ? ? ? ?
HETATM 1770 O O . HOH N 4 . ? 18.673 17.978 1.393 1.00 17.99 ? 415 HOH A O 1 415 ? ? ? ?
HETATM 1771 O O . HOH N 4 . ? 4.962 10.065 11.472 1.00 15.66 ? 416 HOH A O 1 416 ? ? ? ?
HETATM 1772 O O . HOH N 4 . ? 4.846 19.874 -2.388 1.00 20.55 ? 417 HOH A O 1 417 ? ? ? ?
HETATM 1773 O O . HOH N 4 . ? -6.291 14.355 3.817 1.00 38.04 ? 418 HOH A O 1 418 ? ? ? ?
HETATM 1774 O O . HOH N 4 . ? -1.555 7.320 13.112 1.00 17.25 ? 419 HOH A O 1 419 ? ? ? ?
HETATM 1775 O O . HOH N 4 . ? 5.511 28.553 -5.897 1.00 42.66 ? 420 HOH A O 1 420 ? ? ? ?
HETATM 1776 O O . HOH N 4 . ? 18.306 27.938 2.617 1.00 34.98 ? 421 HOH A O 1 421 ? ? ? ?
HETATM 1777 O O . HOH N 4 . ? 19.375 0.737 9.450 1.00 17.68 ? 422 HOH A O 1 422 ? ? ? ?
HETATM 1778 O O . HOH N 4 . ? 23.587 21.595 20.221 1.00 26.09 ? 423 HOH A O 1 423 ? ? ? ?
HETATM 1779 O O . HOH N 4 . ? 22.019 14.609 8.610 1.00 17.40 ? 424 HOH A O 1 424 ? ? ? ?
HETATM 1780 O O . HOH N 4 . ? 22.460 1.508 30.762 1.00 22.67 ? 425 HOH A O 1 425 ? ? ? ?
HETATM 1781 O O . HOH N 4 . ? 10.961 -1.588 37.213 1.00 51.50 ? 426 HOH A O 1 426 ? ? ? ?
HETATM 1782 O O . HOH N 4 . ? 6.519 29.134 -1.035 1.00 39.67 ? 427 HOH A O 1 427 ? ? ? ?
HETATM 1783 O O . HOH N 4 . ? 15.275 20.294 34.047 1.00 19.84 ? 428 HOH A O 1 428 ? ? ? ?
HETATM 1784 O O . HOH N 4 . ? 19.757 27.766 29.084 1.00 17.04 ? 429 HOH A O 1 429 ? ? ? ?
HETATM 1785 O O . HOH N 4 . ? 8.672 23.089 33.395 1.00 21.53 ? 430 HOH A O 1 430 ? ? ? ?
HETATM 1786 O O . HOH N 4 . ? -8.396 27.951 4.091 1.00 21.02 ? 431 HOH A O 1 431 ? ? ? ?
HETATM 1787 O O . HOH N 4 . ? -9.394 26.369 6.532 1.00 17.50 ? 432 HOH A O 1 432 ? ? ? ?
HETATM 1788 O O . HOH N 4 . ? -6.494 29.452 2.316 1.00 19.13 ? 433 HOH A O 1 433 ? ? ? ?
HETATM 1789 O O . HOH N 4 . ? -8.242 20.206 6.078 1.00 14.32 ? 434 HOH A O 1 434 ? ? ? ?
HETATM 1790 O O . HOH N 4 . ? -11.612 17.455 5.476 1.00 29.32 ? 435 HOH A O 1 435 ? ? ? ?
HETATM 1791 O O . HOH N 4 . ? -3.048 32.282 14.325 1.00 12.71 ? 436 HOH A O 1 436 ? ? ? ?
HETATM 1792 O O . HOH N 4 . ? 28.938 4.321 27.650 1.00 50.75 ? 437 HOH A O 1 437 ? ? ? ?
HETATM 1793 O O . HOH N 4 . ? -0.495 35.401 23.236 1.00 21.26 ? 438 HOH A O 1 438 ? ? ? ?
HETATM 1794 O O . HOH N 4 . ? -4.205 27.490 18.146 1.00 10.35 ? 439 HOH A O 1 439 ? ? ? ?
HETATM 1795 O O . HOH N 4 . ? 4.688 31.378 23.031 1.00 33.92 ? 440 HOH A O 1 440 ? ? ? ?
HETATM 1796 O O . HOH N 4 . ? -1.554 31.638 10.484 1.00 20.63 ? 441 HOH A O 1 441 ? ? ? ?
HETATM 1797 O O . HOH N 4 . ? -7.569 11.441 20.688 1.00 31.08 ? 442 HOH A O 1 442 ? ? ? ?
HETATM 1798 O O . HOH N 4 . ? -13.029 20.481 26.009 1.00 37.18 ? 443 HOH A O 1 443 ? ? ? ?
HETATM 1799 O O . HOH N 4 . ? -11.111 16.581 25.053 1.00 29.17 ? 444 HOH A O 1 444 ? ? ? ?
HETATM 1800 O O . HOH N 4 . ? -6.749 9.561 26.832 1.00 15.94 ? 445 HOH A O 1 445 ? ? ? ?
HETATM 1801 O O . HOH N 4 . ? 1.241 1.877 15.017 1.00 32.64 ? 446 HOH A O 1 446 ? ? ? ?
HETATM 1802 O O . HOH N 4 . ? 2.954 -0.952 22.495 1.00 23.24 ? 447 HOH A O 1 447 ? ? ? ?
HETATM 1803 O O . HOH N 4 . ? -12.829 20.382 7.660 1.00 28.61 ? 448 HOH A O 1 448 ? ? ? ?
HETATM 1804 O O . HOH N 4 . ? -5.514 13.966 9.217 1.00 19.11 ? 449 HOH A O 1 449 ? ? ? ?
HETATM 1805 O O . HOH N 4 . ? 6.113 0.180 27.520 1.00 12.82 ? 450 HOH A O 1 450 ? ? ? ?
HETATM 1806 O O . HOH N 4 . ? 4.883 -1.304 20.595 1.00 15.04 ? 451 HOH A O 1 451 ? ? ? ?
HETATM 1807 O O . HOH N 4 . ? 8.313 28.074 3.015 1.00 19.48 ? 452 HOH A O 1 452 ? ? ? ?
HETATM 1808 O O . HOH N 4 . ? -5.798 1.881 26.152 1.00 34.78 ? 453 HOH A O 1 453 ? ? ? ?
HETATM 1809 O O . HOH N 4 . ? -2.967 3.038 27.432 1.00 38.35 ? 454 HOH A O 1 454 ? ? ? ?
HETATM 1810 O O . HOH N 4 . ? -5.383 4.190 29.603 1.00 16.72 ? 455 HOH A O 1 455 ? ? ? ?
HETATM 1811 O O . HOH N 4 . ? 8.647 -1.476 27.251 1.00 14.12 ? 456 HOH A O 1 456 ? ? ? ?
HETATM 1812 O O . HOH N 4 . ? 25.863 18.286 33.991 1.00 23.43 ? 457 HOH A O 1 457 ? ? ? ?
HETATM 1813 O O . HOH N 4 . ? 18.019 25.424 31.837 1.00 40.15 ? 458 HOH A O 1 458 ? ? ? ?
HETATM 1814 O O . HOH N 4 . ? 22.572 26.058 17.201 1.00 13.78 ? 459 HOH A O 1 459 ? ? ? ?
HETATM 1815 O O . HOH N 4 . ? 25.077 16.418 11.370 1.00 17.69 ? 460 HOH A O 1 460 ? ? ? ?
HETATM 1816 O O . HOH N 4 . ? 1.218 20.119 35.447 1.00 37.95 ? 461 HOH A O 1 461 ? ? ? ?
HETATM 1817 O O . HOH N 4 . ? 22.014 3.140 25.148 1.00 29.04 ? 462 HOH A O 1 462 ? ? ? ?
HETATM 1818 O O . HOH N 4 . ? 22.902 2.784 22.062 1.00 14.62 ? 463 HOH A O 1 463 ? ? ? ?
HETATM 1819 O O . HOH N 4 . ? 23.263 0.549 20.429 1.00 17.75 ? 464 HOH A O 1 464 ? ? ? ?
HETATM 1820 O O . HOH N 4 . ? 25.035 -1.510 30.202 1.00 22.69 ? 465 HOH A O 1 465 ? ? ? ?
HETATM 1821 O O . HOH N 4 . ? 29.521 5.846 29.571 1.00 40.47 ? 466 HOH A O 1 466 ? ? ? ?
HETATM 1822 O O . HOH N 4 . ? 27.451 0.845 26.999 1.00 18.88 ? 467 HOH A O 1 467 ? ? ? ?
HETATM 1823 O O . HOH N 4 . ? 27.470 3.126 23.517 1.00 24.19 ? 468 HOH A O 1 468 ? ? ? ?
HETATM 1824 O O . HOH N 4 . ? 24.950 17.030 17.739 1.00 20.81 ? 469 HOH A O 1 469 ? ? ? ?
HETATM 1825 O O . HOH N 4 . ? 36.639 9.671 28.634 1.00 46.22 ? 470 HOH A O 1 470 ? ? ? ?
HETATM 1826 O O . HOH N 4 . ? 40.171 13.001 27.197 1.00 42.82 ? 471 HOH A O 1 471 ? ? ? ?
HETATM 1827 O O . HOH N 4 . ? 13.130 20.433 34.831 1.00 38.85 ? 472 HOH A O 1 472 ? ? ? ?
HETATM 1828 O O . HOH N 4 . ? 21.677 23.697 30.949 1.00 32.92 ? 473 HOH A O 1 473 ? ? ? ?
HETATM 1829 O O . HOH N 4 . ? 15.548 27.163 33.171 1.00 26.31 ? 474 HOH A O 1 474 ? ? ? ?
HETATM 1830 O O . HOH N 4 . ? 8.390 -1.514 36.353 1.00 45.27 ? 475 HOH A O 1 475 ? ? ? ?
HETATM 1831 O O . HOH N 4 . ? 13.826 10.086 35.463 1.00 22.52 ? 476 HOH A O 1 476 ? ? ? ?
HETATM 1832 O O . HOH N 4 . ? 16.498 -3.517 33.766 1.00 33.80 ? 477 HOH A O 1 477 ? ? ? ?
HETATM 1833 O O . HOH N 4 . ? 11.901 0.485 36.313 1.00 45.51 ? 478 HOH A O 1 478 ? ? ? ?
HETATM 1834 O O . HOH N 4 . ? -1.169 13.547 34.815 1.00 24.79 ? 479 HOH A O 1 479 ? ? ? ?
HETATM 1835 O O . HOH N 4 . ? 0.520 10.806 40.312 1.00 28.62 ? 480 HOH A O 1 480 ? ? ? ?
HETATM 1836 O O . HOH N 4 . ? 5.455 34.040 13.553 1.00 24.70 ? 481 HOH A O 1 481 ? ? ? ?
HETATM 1837 O O . HOH N 4 . ? 27.574 10.786 13.173 1.00 45.85 ? 482 HOH A O 1 482 ? ? ? ?
HETATM 1838 O O . HOH N 4 . ? 19.714 9.690 10.080 1.00 29.39 ? 483 HOH A O 1 483 ? ? ? ?
HETATM 1839 O O . HOH N 4 . ? 22.604 6.649 12.784 1.00 21.57 ? 484 HOH A O 1 484 ? ? ? ?
HETATM 1840 O O . HOH N 4 . ? 25.533 19.028 6.239 1.00 46.56 ? 485 HOH A O 1 485 ? ? ? ?
HETATM 1841 O O . HOH N 4 . ? 21.417 15.148 5.485 1.00 38.90 ? 486 HOH A O 1 486 ? ? ? ?
HETATM 1842 O O . HOH N 4 . ? 19.720 4.889 8.467 1.00 21.26 ? 487 HOH A O 1 487 ? ? ? ?
HETATM 1843 O O . HOH N 4 . ? 26.769 19.144 18.635 1.00 35.37 ? 488 HOH A O 1 488 ? ? ? ?
HETATM 1844 O O . HOH N 4 . ? 28.551 14.406 20.292 1.00 46.09 ? 489 HOH A O 1 489 ? ? ? ?
HETATM 1845 O O . HOH N 4 . ? 10.735 -4.008 7.394 1.00 30.74 ? 490 HOH A O 1 490 ? ? ? ?
HETATM 1846 O O . HOH N 4 . ? 7.658 11.292 -1.124 1.00 30.76 ? 491 HOH A O 1 491 ? ? ? ?
HETATM 1847 O O . HOH N 4 . ? 8.177 7.989 9.649 1.00 11.40 ? 492 HOH A O 1 492 ? ? ? ?
HETATM 1848 O O . HOH N 4 . ? 22.497 8.387 8.784 1.00 38.91 ? 493 HOH A O 1 493 ? ? ? ?
HETATM 1849 O O . HOH N 4 . ? -8.310 16.217 8.066 1.00 19.52 ? 495 HOH A O 1 495 ? ? ? ?
HETATM 1850 O O . HOH N 4 . ? -13.685 25.529 22.699 1.00 29.91 ? 496 HOH A O 1 496 ? ? ? ?
HETATM 1851 O O . HOH N 4 . ? -3.927 5.903 15.910 1.00 37.89 ? 497 HOH A O 1 497 ? ? ? ?
HETATM 1852 O O . HOH N 4 . ? 0.729 0.111 21.248 1.00 23.52 ? 498 HOH A O 1 498 ? ? ? ?
HETATM 1853 O O . HOH N 4 . ? 2.422 -0.390 30.465 1.00 24.06 ? 499 HOH A O 1 499 ? ? ? ?
HETATM 1854 O O . HOH N 4 . ? 31.076 28.454 12.062 1.00 48.25 ? 500 HOH A O 1 500 ? ? ? ?
HETATM 1855 O O . HOH N 4 . ? 3.394 11.966 1.455 1.00 14.12 ? 501 HOH A O 1 501 ? ? ? ?
HETATM 1856 O O . HOH N 4 . ? 7.670 26.836 -1.735 1.00 23.36 ? 502 HOH A O 1 502 ? ? ? ?
HETATM 1857 O O . HOH N 4 . ? 16.834 24.261 6.978 1.00 21.40 ? 503 HOH A O 1 503 ? ? ? ?
HETATM 1858 O O . HOH N 4 . ? 0.824 31.418 27.490 1.00 31.06 ? 504 HOH A O 1 504 ? ? ? ?
HETATM 1859 O O . HOH N 4 . ? -8.037 29.740 24.207 1.00 28.47 ? 505 HOH A O 1 505 ? ? ? ?
HETATM 1860 O O . HOH N 4 . ? 12.555 11.528 37.038 1.00 38.05 ? 506 HOH A O 1 506 ? ? ? ?
HETATM 1861 O O . HOH N 4 . ? -10.435 34.052 19.730 1.00 39.82 ? 507 HOH A O 1 507 ? ? ? ?
HETATM 1862 O O . HOH N 4 . ? 2.334 10.224 6.899 1.00 18.04 ? 508 HOH A O 1 508 ? ? ? ?
HETATM 1863 O O . HOH N 4 . ? 27.635 7.378 21.555 1.00 24.09 ? 509 HOH A O 1 509 ? ? ? ?
HETATM 1864 O O . HOH N 4 . ? 27.895 8.821 19.566 1.00 32.74 ? 510 HOH A O 1 510 ? ? ? ?
HETATM 1865 O O . HOH N 4 . ? 10.451 21.264 34.878 1.00 28.15 ? 511 HOH A O 1 511 ? ? ? ?
HETATM 1866 O O . HOH N 4 . ? 0.233 3.884 36.551 1.00 25.40 ? 512 HOH A O 1 512 ? ? ? ?
HETATM 1867 O O . HOH N 4 . ? -15.894 20.940 4.742 1.00 41.23 ? 513 HOH A O 1 513 ? ? ? ?
HETATM 1868 O O . HOH N 4 . ? -8.128 12.502 15.408 1.00 37.20 ? 514 HOH A O 1 514 ? ? ? ?
HETATM 1869 O O . HOH N 4 . ? -17.792 16.651 15.300 1.00 45.58 ? 515 HOH A O 1 515 ? ? ? ?
HETATM 1870 O O . HOH N 4 . ? -0.861 4.570 13.429 1.00 38.31 ? 516 HOH A O 1 516 ? ? ? ?
HETATM 1871 O O . HOH N 4 . ? 6.698 4.609 6.398 1.00 44.88 ? 517 HOH A O 1 517 ? ? ? ?
HETATM 1872 O O . HOH N 4 . ? 1.910 5.868 9.950 1.00 26.79 ? 518 HOH A O 1 518 ? ? ? ?
HETATM 1873 O O . HOH N 4 . ? 5.478 -1.534 12.919 1.00 29.12 ? 519 HOH A O 1 519 ? ? ? ?
HETATM 1874 O O . HOH N 4 . ? 24.020 25.208 19.307 1.00 29.02 ? 520 HOH A O 1 520 ? ? ? ?
HETATM 1875 O O . HOH N 4 . ? -7.165 14.143 13.031 1.00 24.95 ? 521 HOH A O 1 521 ? ? ? ?
HETATM 1876 O O . HOH N 4 . ? -6.163 9.682 11.297 1.00 39.25 ? 522 HOH A O 1 522 ? ? ? ?
HETATM 1877 O O . HOH N 4 . ? -8.331 17.850 29.299 1.00 41.64 ? 523 HOH A O 1 523 ? ? ? ?
HETATM 1878 O O . HOH N 4 . ? -8.305 6.838 11.398 1.00 45.09 ? 524 HOH A O 1 524 ? ? ? ?
HETATM 1879 O O . HOH N 4 . ? 41.567 8.380 28.822 1.00 47.58 ? 526 HOH A O 1 526 ? ? ? ?
HETATM 1880 O O . HOH N 4 . ? -13.019 21.405 5.063 1.00 40.04 ? 527 HOH A O 1 527 ? ? ? ?
HETATM 1881 O O . HOH N 4 . ? 25.532 15.224 34.141 1.00 31.70 ? 528 HOH A O 1 528 ? ? ? ?
HETATM 1882 O O . HOH N 4 . ? 21.633 8.375 37.044 1.00 45.86 ? 529 HOH A O 1 529 ? ? ? ?
HETATM 1883 O O . HOH N 4 . ? 22.722 23.229 22.323 1.00 26.58 ? 530 HOH A O 1 530 ? ? ? ?
HETATM 1884 O O . HOH N 4 . ? -6.948 13.888 6.824 1.00 41.57 ? 531 HOH A O 1 531 ? ? ? ?
HETATM 1885 O O . HOH N 4 . ? 23.924 18.152 36.619 1.00 48.85 ? 532 HOH A O 1 532 ? ? ? ?
HETATM 1886 O O . HOH N 4 . ? 28.832 24.200 19.922 1.00 45.00 ? 533 HOH A O 1 533 ? ? ? ?
HETATM 1887 O O . HOH N 4 . ? 26.202 21.908 12.991 1.00 22.82 ? 534 HOH A O 1 534 ? ? ? ?
HETATM 1888 O O . HOH N 4 . ? 32.409 18.529 16.613 1.00 46.98 ? 535 HOH A O 1 535 ? ? ? ?
HETATM 1889 O O . HOH N 4 . ? 21.935 19.797 6.943 1.00 36.09 ? 536 HOH A O 1 536 ? ? ? ?
HETATM 1890 O O . HOH N 4 . ? 22.962 18.699 3.405 1.00 43.59 ? 537 HOH A O 1 537 ? ? ? ?
HETATM 1891 O O . HOH N 4 . ? 13.387 29.653 3.130 1.00 27.31 ? 538 HOH A O 1 538 ? ? ? ?
HETATM 1892 O O . HOH N 4 . ? 13.190 26.961 1.851 1.00 17.12 ? 539 HOH A O 1 539 ? ? ? ?
HETATM 1893 O O . HOH N 4 . ? 14.967 27.940 5.916 1.00 27.05 ? 540 HOH A O 1 540 ? ? ? ?
HETATM 1894 O O . HOH N 4 . ? 25.253 26.444 11.665 1.00 32.57 ? 541 HOH A O 1 541 ? ? ? ?
HETATM 1895 O O . HOH N 4 . ? 14.617 24.380 -2.116 1.00 29.62 ? 542 HOH A O 1 542 ? ? ? ?
HETATM 1896 O O . HOH N 4 . ? 9.379 10.834 4.515 1.00 19.66 ? 543 HOH A O 1 543 ? ? ? ?
HETATM 1897 O O . HOH N 4 . ? 5.986 -3.565 30.227 1.00 35.91 ? 544 HOH A O 1 544 ? ? ? ?
HETATM 1898 O O . HOH N 4 . ? 9.866 3.268 34.551 1.00 26.51 ? 545 HOH A O 1 545 ? ? ? ?
HETATM 1899 O O . HOH N 4 . ? 6.758 15.619 -2.277 1.00 17.44 ? 546 HOH A O 1 546 ? ? ? ?
HETATM 1900 O O . HOH N 4 . ? 11.481 18.506 0.762 1.00 17.00 ? 547 HOH A O 1 547 ? ? ? ?
HETATM 1901 O O . HOH N 4 . ? 8.981 18.774 -0.870 1.00 20.29 ? 548 HOH A O 1 548 ? ? ? ?
HETATM 1902 O O . HOH N 4 . ? 1.507 22.204 -8.499 1.00 25.49 ? 549 HOH A O 1 549 ? ? ? ?
HETATM 1903 O O . HOH N 4 . ? 2.122 28.775 -1.865 1.00 28.59 ? 550 HOH A O 1 550 ? ? ? ?
HETATM 1904 O O . HOH N 4 . ? 2.011 29.105 0.567 1.00 15.84 ? 551 HOH A O 1 551 ? ? ? ?
HETATM 1905 O O . HOH N 4 . ? -0.326 30.697 -0.801 1.00 21.77 ? 552 HOH A O 1 552 ? ? ? ?
HETATM 1906 O O . HOH N 4 . ? 25.905 9.157 17.756 1.00 27.07 ? 553 HOH A O 1 553 ? ? ? ?
HETATM 1907 O O . HOH N 4 . ? 23.075 9.347 14.814 1.00 33.94 ? 554 HOH A O 1 554 ? ? ? ?
HETATM 1908 O O . HOH N 4 . ? 30.780 10.444 32.727 1.00 42.06 ? 555 HOH A O 1 555 ? ? ? ?
HETATM 1909 O O . HOH N 4 . ? 27.189 22.717 20.976 1.00 42.07 ? 556 HOH A O 1 556 ? ? ? ?
HETATM 1910 O O . HOH N 4 . ? 12.081 28.073 14.536 1.00 21.96 ? 557 HOH A O 1 557 ? ? ? ?
HETATM 1911 O O . HOH N 4 . ? 8.309 8.060 38.407 1.00 41.11 ? 558 HOH A O 1 558 ? ? ? ?
HETATM 1912 O O . HOH N 4 . ? 36.173 22.968 38.537 1.00 44.24 ? 559 HOH A O 1 559 ? ? ? ?
HETATM 1913 O O . HOH N 4 . ? 27.501 24.054 33.236 1.00 45.30 ? 560 HOH A O 1 560 ? ? ? ?
HETATM 1914 O O . HOH N 4 . ? 12.059 13.990 35.061 1.00 35.19 ? 561 HOH A O 1 561 ? ? ? ?
HETATM 1915 O O . HOH N 4 . ? 17.169 6.986 36.054 1.00 36.94 ? 562 HOH A O 1 562 ? ? ? ?
HETATM 1916 O O . HOH N 4 . ? 12.268 8.321 34.229 1.00 36.01 ? 563 HOH A O 1 563 ? ? ? ?
HETATM 1917 O O . HOH N 4 . ? 28.291 24.401 41.033 1.00 43.64 ? 564 HOH A O 1 564 ? ? ? ?
HETATM 1918 O O . HOH N 4 . ? 39.134 8.702 29.298 1.00 50.65 ? 565 HOH A O 1 565 ? ? ? ?
HETATM 1919 O O . HOH N 4 . ? 31.151 15.596 30.428 1.00 38.78 ? 566 HOH A O 1 566 ? ? ? ?
HETATM 1920 O O . HOH N 4 . ? 24.538 11.880 36.890 1.00 45.84 ? 567 HOH A O 1 567 ? ? ? ?
HETATM 1921 O O . HOH N 4 . ? -2.718 37.161 24.280 1.00 47.36 ? 568 HOH A O 1 568 ? ? ? ?
HETATM 1922 O O . HOH N 4 . ? 21.206 29.653 30.593 1.00 40.54 ? 569 HOH A O 1 569 ? ? ? ?
HETATM 1923 O O . HOH N 4 . ? -3.485 7.314 10.903 1.00 40.99 ? 570 HOH A O 1 570 ? ? ? ?
HETATM 1924 O O . HOH N 4 . ? -6.758 14.326 19.672 1.00 19.16 ? 571 HOH A O 1 571 ? ? ? ?
HETATM 1925 O O . HOH N 4 . ? -16.768 28.074 25.430 1.00 44.17 ? 572 HOH A O 1 572 ? ? ? ?
HETATM 1926 O O . HOH N 4 . ? -14.556 25.786 14.259 1.00 38.41 ? 573 HOH A O 1 573 ? ? ? ?
HETATM 1927 O O . HOH N 4 . ? -12.275 27.067 19.093 1.00 46.47 ? 574 HOH A O 1 574 ? ? ? ?
HETATM 1928 O O . HOH N 4 . ? -2.916 14.362 30.005 1.00 34.04 ? 575 HOH A O 1 575 ? ? ? ?
HETATM 1929 O O . HOH N 4 . ? -2.984 -1.169 21.953 1.00 43.34 ? 576 HOH A O 1 576 ? ? ? ?
HETATM 1930 O O . HOH N 4 . ? -8.720 16.705 33.714 1.00 44.55 ? 577 HOH A O 1 577 ? ? ? ?
HETATM 1931 O O . HOH N 4 . ? 2.783 1.590 17.278 1.00 35.26 ? 578 HOH A O 1 578 ? ? ? ?
HETATM 1932 O O . HOH N 4 . ? -8.643 3.195 26.772 1.00 39.47 ? 579 HOH A O 1 579 ? ? ? ?
HETATM 1933 O O . HOH N 4 . ? -13.707 28.081 10.703 1.00 39.97 ? 580 HOH A O 1 580 ? ? ? ?
HETATM 1934 O O . HOH N 4 . ? -11.675 29.140 8.855 1.00 36.82 ? 581 HOH A O 1 581 ? ? ? ?
HETATM 1935 O O . HOH N 4 . ? -14.198 17.718 8.352 1.00 39.74 ? 582 HOH A O 1 582 ? ? ? ?
HETATM 1936 O O . HOH N 4 . ? 25.012 1.227 30.432 1.00 24.97 ? 583 HOH A O 1 583 ? ? ? ?
HETATM 1937 O O . HOH N 4 . ? 27.962 6.925 35.394 1.00 42.72 ? 584 HOH A O 1 584 ? ? ? ?
HETATM 1938 O O . HOH N 4 . ? -6.679 31.207 26.393 1.00 35.64 ? 585 HOH A O 1 585 ? ? ? ?
HETATM 1939 O O . HOH N 4 . ? 1.387 14.738 39.661 1.00 39.52 ? 586 HOH A O 1 586 ? ? ? ?
HETATM 1940 O O . HOH N 4 . ? -4.344 4.150 17.434 1.00 42.08 ? 587 HOH A O 1 587 ? ? ? ?
HETATM 1941 O O . HOH N 4 . ? -9.858 15.751 28.824 1.00 40.07 ? 588 HOH A O 1 588 ? ? ? ?
HETATM 1942 O O . HOH N 4 . ? -13.513 13.262 22.225 1.00 41.31 ? 589 HOH A O 1 589 ? ? ? ?
HETATM 1943 O O . HOH N 4 . ? 1.537 -4.631 25.262 1.00 46.06 ? 590 HOH A O 1 590 ? ? ? ?
HETATM 1944 O O . HOH N 4 . ? 3.781 3.665 9.450 1.00 40.68 ? 591 HOH A O 1 591 ? ? ? ?
HETATM 1945 O O . HOH N 4 . ? -19.130 19.594 17.482 1.00 47.92 ? 592 HOH A O 1 592 ? ? ? ?
HETATM 1946 O O . HOH N 4 . ? -17.591 18.992 11.200 1.00 42.07 ? 593 HOH A O 1 593 ? ? ? ?
HETATM 1947 O O . HOH N 4 . ? -8.289 28.557 26.767 1.00 35.84 ? 594 HOH A O 1 594 ? ? ? ?
HETATM 1948 O O . HOH N 4 . ? 28.214 16.974 44.421 1.00 46.89 ? 595 HOH A O 1 595 ? ? ? ?
HETATM 1949 O O . HOH N 4 . ? 19.366 12.506 39.707 1.00 45.18 ? 596 HOH A O 1 596 ? ? ? ?
HETATM 1950 O O . HOH N 4 . ? 24.503 3.251 33.584 1.00 44.53 ? 597 HOH A O 1 597 ? ? ? ?
HETATM 1951 O O . HOH N 4 . ? -0.304 29.930 4.922 1.00 36.08 ? 598 HOH A O 1 598 ? ? ? ?
HETATM 1952 O O . HOH N 4 . ? 12.525 23.558 -3.652 1.00 41.53 ? 599 HOH A O 1 599 ? ? ? ?
HETATM 1953 O O . HOH N 4 . ? 26.350 25.645 15.576 1.00 40.86 ? 600 HOH A O 1 600 ? ? ? ?
HETATM 1954 O O . HOH N 4 . ? 25.387 20.505 22.479 1.00 42.80 ? 601 HOH A O 1 601 ? ? ? ?
HETATM 1955 O O . HOH N 4 . ? 26.503 23.281 25.890 1.00 43.16 ? 602 HOH A O 1 602 ? ? ? ?
HETATM 1956 O O . HOH N 4 . ? 24.779 24.324 13.752 1.00 22.94 ? 603 HOH A O 1 603 ? ? ? ?
HETATM 1957 O O . HOH N 4 . ? 28.373 26.346 12.573 1.00 41.00 ? 604 HOH A O 1 604 ? ? ? ?
HETATM 1958 O O . HOH N 4 . ? 23.611 16.689 5.975 1.00 37.31 ? 605 HOH A O 1 605 ? ? ? ?
HETATM 1959 O O . HOH N 4 . ? 14.228 28.391 8.555 1.00 29.03 ? 606 HOH A O 1 606 ? ? ? ?
HETATM 1960 O O . HOH N 4 . ? 12.968 30.201 13.018 1.00 24.20 ? 607 HOH A O 1 607 ? ? ? ?
HETATM 1961 O O . HOH N 4 . ? 22.506 18.301 8.826 1.00 22.93 ? 608 HOH A O 1 608 ? ? ? ?
HETATM 1962 O O . HOH N 4 . ? 30.649 3.927 31.740 1.00 40.70 ? 609 HOH A O 1 609 ? ? ? ?
HETATM 1963 O O . HOH N 4 . ? 19.566 3.018 42.986 1.00 38.91 ? 610 HOH A O 1 610 ? ? ? ?
HETATM 1964 O O . HOH N 4 . ? 7.223 0.380 10.440 1.00 29.38 ? 611 HOH A O 1 611 ? ? ? ?
HETATM 1965 O O . HOH N 4 . ? 9.035 5.424 9.034 1.00 15.28 ? 612 HOH A O 1 612 ? ? ? ?
HETATM 1966 O O . HOH N 4 . ? 0.260 2.092 29.573 1.00 18.67 ? 613 HOH A O 1 613 ? ? ? ?
HETATM 1967 O O . HOH N 4 . ? 2.004 -2.615 28.873 1.00 27.49 ? 614 HOH A O 1 614 ? ? ? ?
HETATM 1968 O O . HOH N 4 . ? 1.781 5.126 39.556 1.00 33.54 ? 615 HOH A O 1 615 ? ? ? ?
HETATM 1969 O O . HOH N 4 . ? 9.780 0.973 33.115 1.00 36.15 ? 616 HOH A O 1 616 ? ? ? ?
HETATM 1970 O O . HOH N 4 . ? -0.748 0.764 32.788 0.50 7.80 ? 617 HOH A O 1 617 ? ? ? ?
HETATM 1971 O O . HOH N 4 . ? -1.244 3.415 34.958 1.00 12.13 ? 618 HOH A O 1 618 ? ? ? ?
HETATM 1972 O O . HOH N 4 . ? -6.566 13.562 27.564 1.00 29.93 ? 619 HOH A O 1 619 ? ? ? ?
HETATM 1973 O O . HOH N 4 . ? -11.335 20.003 32.329 1.00 40.74 ? 620 HOH A O 1 620 ? ? ? ?
HETATM 1974 O O . HOH N 4 . ? -10.196 22.226 33.926 1.00 37.28 ? 621 HOH A O 1 621 ? ? ? ?
HETATM 1975 O O . HOH N 4 . ? -13.484 18.678 29.164 1.00 37.00 ? 622 HOH A O 1 622 ? ? ? ?
HETATM 1976 O O . HOH N 4 . ? -7.401 14.546 34.055 1.00 36.37 ? 623 HOH A O 1 623 ? ? ? ?
HETATM 1977 O O . HOH N 4 . ? -8.806 26.551 30.333 1.00 35.02 ? 624 HOH A O 1 624 ? ? ? ?
HETATM 1978 O O . HOH N 4 . ? -11.109 28.071 27.148 1.00 38.17 ? 625 HOH A O 1 625 ? ? ? ?
HETATM 1979 O O . HOH N 4 . ? -12.675 27.659 23.580 1.00 30.31 ? 626 HOH A O 1 626 ? ? ? ?
HETATM 1980 O O . HOH N 4 . ? -14.430 24.075 24.457 1.00 34.52 ? 627 HOH A O 1 627 ? ? ? ?
HETATM 1981 O O . HOH N 4 . ? -15.898 21.208 20.175 1.00 30.33 ? 628 HOH A O 1 628 ? ? ? ?
HETATM 1982 O O . HOH N 4 . ? -20.021 30.193 22.188 1.00 41.81 ? 629 HOH A O 1 629 ? ? ? ?
HETATM 1983 O O . HOH N 4 . ? -17.851 22.541 31.983 1.00 39.87 ? 630 HOH A O 1 630 ? ? ? ?
HETATM 1984 O O . HOH N 4 . ? 40.239 15.903 26.310 1.00 37.26 ? 631 HOH A O 1 631 ? ? ? ?
HETATM 1985 O O . HOH N 4 . ? -14.321 23.407 26.999 1.00 31.01 ? 632 HOH A O 1 632 ? ? ? ?
HETATM 1986 O O . HOH N 4 . ? -10.379 14.595 23.291 1.00 38.05 ? 633 HOH A O 1 633 ? ? ? ?
HETATM 1987 O O . HOH N 4 . ? -8.188 12.614 24.665 1.00 37.90 ? 634 HOH A O 1 634 ? ? ? ?
HETATM 1988 O O . HOH N 4 . ? -11.930 13.807 13.229 1.00 34.37 ? 635 HOH A O 1 635 ? ? ? ?
HETATM 1989 O O . HOH N 4 . ? -15.663 14.538 10.976 1.00 35.90 ? 636 HOH A O 1 636 ? ? ? ?
HETATM 1990 O O . HOH N 4 . ? -10.601 11.596 11.990 1.00 36.96 ? 637 HOH A O 1 637 ? ? ? ?
HETATM 1991 O O . HOH N 4 . ? -10.602 11.113 17.302 1.00 39.92 ? 638 HOH A O 1 638 ? ? ? ?
HETATM 1992 O O . HOH N 4 . ? -16.527 15.294 13.687 1.00 39.11 ? 639 HOH A O 1 639 ? ? ? ?
HETATM 1993 O O . HOH N 4 . ? -21.965 15.223 19.555 1.00 37.42 ? 640 HOH A O 1 640 ? ? ? ?
HETATM 1994 O O . HOH N 4 . ? -10.188 13.112 14.576 1.00 37.79 ? 641 HOH A O 1 641 ? ? ? ?
HETATM 1995 O O . HOH N 4 . ? 1.182 7.401 11.931 1.00 26.77 ? 642 HOH A O 1 642 ? ? ? ?
HETATM 1996 O O . HOH N 4 . ? -4.871 7.629 6.873 1.00 39.14 ? 643 HOH A O 1 643 ? ? ? ?
HETATM 1997 O O . HOH N 4 . ? -5.456 5.247 10.791 1.00 43.19 ? 644 HOH A O 1 644 ? ? ? ?
HETATM 1998 O O . HOH N 4 . ? -1.891 7.891 9.158 1.00 34.42 ? 645 HOH A O 1 645 ? ? ? ?
HETATM 1999 O O . HOH N 4 . ? 2.151 10.435 11.507 1.00 21.06 ? 646 HOH A O 1 646 ? ? ? ?
HETATM 2000 O O . HOH N 4 . ? -4.124 1.779 12.115 1.00 39.49 ? 647 HOH A O 1 647 ? ? ? ?
HETATM 2001 O O . HOH N 4 . ? -2.182 -2.553 12.547 1.00 39.79 ? 648 HOH A O 1 648 ? ? ? ?
HETATM 2002 O O . HOH N 4 . ? 1.277 4.392 22.275 1.00 16.14 ? 649 HOH A O 1 649 ? ? ? ?
HETATM 2003 O O . HOH N 4 . ? -4.470 -2.225 20.535 1.00 38.80 ? 650 HOH A O 1 650 ? ? ? ?
HETATM 2004 O O . HOH N 4 . ? -2.936 -5.664 19.589 1.00 34.72 ? 651 HOH A O 1 651 ? ? ? ?
HETATM 2005 O O . HOH N 4 . ? -9.267 4.913 17.843 1.00 36.89 ? 652 HOH A O 1 652 ? ? ? ?
HETATM 2006 O O . HOH N 4 . ? 1.045 -4.812 16.074 1.00 42.21 ? 653 HOH A O 1 653 ? ? ? ?
HETATM 2007 O O . HOH N 4 . ? 0.793 1.596 18.736 1.00 25.66 ? 654 HOH A O 1 654 ? ? ? ?
HETATM 2008 O O . HOH N 4 . ? -1.551 1.571 16.986 1.00 37.09 ? 655 HOH A O 1 655 ? ? ? ?
HETATM 2009 O O . HOH N 4 . ? -7.166 3.720 19.186 1.00 38.18 ? 656 HOH A O 1 656 ? ? ? ?
HETATM 2010 O O . HOH N 4 . ? -5.423 5.889 24.999 1.00 31.48 ? 657 HOH A O 1 657 ? ? ? ?
HETATM 2011 O O . HOH N 4 . ? -6.474 3.797 24.320 1.00 36.65 ? 658 HOH A O 1 658 ? ? ? ?
HETATM 2012 O O . HOH N 4 . ? -8.324 9.719 22.401 1.00 34.18 ? 659 HOH A O 1 659 ? ? ? ?
HETATM 2013 O O . HOH N 4 . ? -21.920 17.978 20.088 1.00 41.94 ? 660 HOH A O 1 660 ? ? ? ?
HETATM 2014 O O . HOH N 4 . ? -20.601 20.392 22.586 1.00 39.04 ? 661 HOH A O 1 661 ? ? ? ?
HETATM 2015 O O . HOH N 4 . ? -9.816 32.968 11.683 1.00 23.69 ? 662 HOH A O 1 662 ? ? ? ?
HETATM 2016 O O . HOH N 4 . ? -6.062 38.514 17.219 1.00 36.00 ? 663 HOH A O 1 663 ? ? ? ?
HETATM 2017 O O . HOH N 4 . ? 1.280 33.796 18.076 1.00 24.16 ? 664 HOH A O 1 664 ? ? ? ?
HETATM 2018 O O . HOH N 4 . ? 4.129 37.987 19.531 1.00 35.80 ? 665 HOH A O 1 665 ? ? ? ?
HETATM 2019 O O . HOH N 4 . ? -0.202 35.330 19.709 1.00 22.09 ? 666 HOH A O 1 666 ? ? ? ?
HETATM 2020 O O . HOH N 4 . ? 6.694 36.610 12.964 1.00 15.53 ? 667 HOH A O 1 667 ? ? ? ?
HETATM 2021 O O . HOH N 4 . ? 10.576 37.213 11.232 1.00 15.81 ? 668 HOH A O 1 668 ? ? ? ?
HETATM 2022 O O . HOH N 4 . ? -12.683 31.558 11.310 1.00 38.87 ? 669 HOH A O 1 669 ? ? ? ?
HETATM 2023 O O . HOH N 4 . ? -9.451 34.901 13.852 1.00 37.91 ? 670 HOH A O 1 670 ? ? ? ?
HETATM 2024 O O . HOH N 4 . ? -16.001 35.451 17.967 1.00 38.54 ? 671 HOH A O 1 671 ? ? ? ?
HETATM 2025 O O . HOH N 4 . ? -5.559 32.964 4.007 1.00 35.34 ? 672 HOH A O 1 672 ? ? ? ?
HETATM 2026 O O . HOH N 4 . ? -2.360 34.744 5.454 1.00 36.52 ? 673 HOH A O 1 673 ? ? ? ?
HETATM 2027 O O . HOH N 4 . ? -6.959 36.151 9.780 1.00 40.29 ? 674 HOH A O 1 674 ? ? ? ?
HETATM 2028 O O . HOH N 4 . ? -4.724 21.724 33.650 1.00 35.66 ? 675 HOH A O 1 675 ? ? ? ?
HETATM 2029 O O . HOH N 4 . ? 16.615 29.767 34.870 1.00 21.38 ? 676 HOH A O 1 676 ? ? ? ?
HETATM 2030 O O . HOH N 4 . ? 17.961 25.149 35.206 1.00 34.34 ? 677 HOH A O 1 677 ? ? ? ?
HETATM 2031 O O . HOH N 4 . ? 21.876 29.470 36.726 1.00 39.97 ? 678 HOH A O 1 678 ? ? ? ?
HETATM 2032 O O . HOH N 4 . ? 7.395 10.655 2.976 1.00 28.48 ? 679 HOH A O 1 679 ? ? ? ?
HETATM 2033 O O . HOH N 4 . ? 4.670 17.191 -2.383 1.00 22.79 ? 680 HOH A O 1 680 ? ? ? ?
HETATM 2034 O O . HOH N 4 . ? 10.909 3.564 2.888 1.00 24.59 ? 681 HOH A O 1 681 ? ? ? ?
HETATM 2035 O O . HOH N 4 . ? 2.873 8.388 4.829 1.00 39.34 ? 683 HOH A O 1 683 ? ? ? ?
HETATM 2036 O O . HOH N 4 . ? 5.919 5.404 4.317 1.00 38.43 ? 684 HOH A O 1 684 ? ? ? ?
HETATM 2037 O O . HOH N 4 . ? -0.620 9.519 7.772 1.00 27.80 ? 685 HOH A O 1 685 ? ? ? ?
HETATM 2038 O O . HOH N 4 . ? 24.668 24.143 36.452 1.00 36.81 ? 686 HOH A O 1 686 ? ? ? ?
HETATM 2039 O O . HOH N 4 . ? -6.549 4.915 8.425 1.00 42.30 ? 687 HOH A O 1 687 ? ? ? ?
HETATM 2040 O O . HOH N 4 . ? 1.658 -2.844 10.585 1.00 40.97 ? 688 HOH A O 1 688 ? ? ? ?
HETATM 2041 O O . HOH N 4 . ? -5.670 -5.406 10.078 1.00 39.53 ? 689 HOH A O 1 689 ? ? ? ?
HETATM 2042 O O . HOH N 4 . ? 4.343 0.311 10.991 1.00 39.79 ? 690 HOH A O 1 690 ? ? ? ?
HETATM 2043 O O . HOH N 4 . ? -0.999 1.472 27.475 1.00 36.76 ? 691 HOH A O 1 691 ? ? ? ?
HETATM 2044 O O . HOH N 4 . ? 8.762 -0.330 30.375 1.00 23.64 ? 692 HOH A O 1 692 ? ? ? ?
HETATM 2045 O O . HOH N 4 . ? 4.455 -3.297 32.126 1.00 38.10 ? 693 HOH A O 1 693 ? ? ? ?
HETATM 2046 O O . HOH N 4 . ? 3.704 5.292 37.706 1.00 30.57 ? 694 HOH A O 1 694 ? ? ? ?
HETATM 2047 O O . HOH N 4 . ? 5.660 7.951 37.805 1.00 31.46 ? 695 HOH A O 1 695 ? ? ? ?
HETATM 2048 O O . HOH N 4 . ? 6.706 9.884 42.779 1.00 38.57 ? 696 HOH A O 1 696 ? ? ? ?
HETATM 2049 O O . HOH N 4 . ? 9.157 2.771 36.932 1.00 40.75 ? 697 HOH A O 1 697 ? ? ? ?
HETATM 2050 O O . HOH N 4 . ? 32.111 19.452 14.268 1.00 38.27 ? 698 HOH A O 1 698 ? ? ? ?
HETATM 2051 O O . HOH N 4 . ? 14.840 6.200 42.054 1.00 38.07 ? 699 HOH A O 1 699 ? ? ? ?
HETATM 2052 O O . HOH N 4 . ? -16.720 23.193 7.499 1.00 33.52 ? 700 HOH A O 1 700 ? ? ? ?
HETATM 2053 O O . HOH N 4 . ? -23.382 13.365 19.381 1.00 38.44 ? 701 HOH A O 1 701 ? ? ? ?
HETATM 2054 O O . HOH N 4 . ? -1.536 -3.351 8.820 1.00 41.72 ? 702 HOH A O 1 702 ? ? ? ?
HETATM 2055 O O . HOH N 4 . ? 27.000 28.403 14.500 1.00 35.35 ? 703 HOH A O 1 703 ? ? ? ?
HETATM 2056 O O . HOH N 4 . ? 25.500 25.154 31.950 1.00 37.91 ? 704 HOH A O 1 704 ? ? ? ?
HETATM 2057 O O . HOH N 4 . ? 30.745 25.713 33.898 1.00 39.17 ? 705 HOH A O 1 705 ? ? ? ?
HETATM 2058 O O . HOH N 4 . ? 29.947 28.558 34.378 1.00 38.53 ? 706 HOH A O 1 706 ? ? ? ?
HETATM 2059 O O . HOH N 4 . ? 30.956 17.849 26.658 1.00 40.21 ? 707 HOH A O 1 707 ? ? ? ?
HETATM 2060 O O . HOH N 4 . ? 11.281 27.039 -2.260 1.00 37.80 ? 708 HOH A O 1 708 ? ? ? ?
HETATM 2061 O O . HOH N 4 . ? 11.356 25.603 -4.160 1.00 19.81 ? 709 HOH A O 1 709 ? ? ? ?
HETATM 2062 O O . HOH N 4 . ? 25.522 14.451 7.503 1.00 40.69 ? 710 HOH A O 1 710 ? ? ? ?
HETATM 2063 O O . HOH N 4 . ? 17.980 21.492 -1.349 1.00 27.11 ? 711 HOH A O 1 711 ? ? ? ?
HETATM 2064 O O . HOH N 4 . ? 15.046 21.685 -0.881 1.00 19.73 ? 712 HOH A O 1 712 ? ? ? ?
HETATM 2065 O O . HOH N 4 . ? 16.978 18.234 -5.246 1.00 32.71 ? 713 HOH A O 1 713 ? ? ? ?
HETATM 2066 O O . HOH N 4 . ? 14.220 18.643 -5.201 1.00 27.92 ? 714 HOH A O 1 714 ? ? ? ?
HETATM 2067 O O . HOH N 4 . ? 10.230 23.742 -4.691 1.00 39.60 ? 715 HOH A O 1 715 ? ? ? ?
HETATM 2068 O O . HOH N 4 . ? 10.014 29.335 -0.670 1.00 34.16 ? 716 HOH A O 1 716 ? ? ? ?
HETATM 2069 O O . HOH N 4 . ? 18.791 10.652 7.332 1.00 30.34 ? 717 HOH A O 1 717 ? ? ? ?
HETATM 2070 O O . HOH N 4 . ? 23.831 14.071 10.291 1.00 35.81 ? 718 HOH A O 1 718 ? ? ? ?
HETATM 2071 O O . HOH N 4 . ? 24.167 14.375 15.615 1.00 30.21 ? 719 HOH A O 1 719 ? ? ? ?
HETATM 2072 O O . HOH N 4 . ? 25.079 4.057 23.199 1.00 22.87 ? 720 HOH A O 1 720 ? ? ? ?
HETATM 2073 O O . HOH N 4 . ? 25.836 3.036 27.972 1.00 21.93 ? 721 HOH A O 1 721 ? ? ? ?
HETATM 2074 O O . HOH N 4 . ? 28.043 12.268 34.061 1.00 34.14 ? 722 HOH A O 1 722 ? ? ? ?
HETATM 2075 O O . HOH N 4 . ? 23.938 13.206 34.651 1.00 39.59 ? 723 HOH A O 1 723 ? ? ? ?
HETATM 2076 O O . HOH N 4 . ? -4.396 34.630 23.941 1.00 31.48 ? 724 HOH A O 1 724 ? ? ? ?
HETATM 2077 O O . HOH N 4 . ? -6.109 38.402 25.632 1.00 40.42 ? 725 HOH A O 1 725 ? ? ? ?
HETATM 2078 O O . HOH N 4 . ? 13.461 -0.432 0.624 1.00 27.95 ? 726 HOH A O 1 726 ? ? ? ?
HETATM 2079 O O . HOH N 4 . ? 1.709 10.114 1.668 1.00 32.93 ? 727 HOH A O 1 727 ? ? ? ?
HETATM 2080 O O . HOH N 4 . ? 19.758 25.418 29.799 1.00 36.87 ? 728 HOH A O 1 728 ? ? ? ?
HETATM 2081 O O . HOH N 4 . ? -1.988 0.486 12.633 1.00 37.33 ? 729 HOH A O 1 729 ? ? ? ?
HETATM 2082 O O . HOH N 4 . ? 2.220 1.849 11.782 1.00 35.02 ? 730 HOH A O 1 730 ? ? ? ?
HETATM 2083 O O . HOH N 4 . ? 24.417 20.875 17.731 1.00 35.78 ? 731 HOH A O 1 731 ? ? ? ?
HETATM 2084 O O . HOH N 4 . ? 25.958 27.841 16.432 1.00 31.79 ? 732 HOH A O 1 732 ? ? ? ?
HETATM 2085 O O . HOH N 4 . ? 11.648 -2.382 9.865 1.00 30.54 ? 733 HOH A O 1 733 ? ? ? ?
HETATM 2086 O O . HOH N 4 . ? 20.755 18.378 5.250 1.00 29.63 ? 734 HOH A O 1 734 ? ? ? ?
HETATM 2087 O O . HOH N 4 . ? 27.663 22.494 7.771 1.00 34.85 ? 735 HOH A O 1 735 ? ? ? ?
HETATM 2088 O O . HOH N 4 . ? 18.882 25.126 7.356 1.00 12.81 ? 736 HOH A O 1 736 ? ? ? ?
HETATM 2089 O O . HOH N 4 . ? 21.297 26.096 7.062 1.00 24.71 ? 737 HOH A O 1 737 ? ? ? ?
HETATM 2090 O O . HOH N 4 . ? 21.994 24.721 2.951 1.00 41.40 ? 738 HOH A O 1 738 ? ? ? ?
HETATM 2091 O O . HOH N 4 . ? 20.417 26.270 2.422 1.00 33.90 ? 739 HOH A O 1 739 ? ? ? ?
HETATM 2092 O O . HOH N 4 . ? 12.390 18.975 -3.298 1.00 30.88 ? 740 HOH A O 1 740 ? ? ? ?
HETATM 2093 O O . HOH N 4 . ? 25.921 19.231 9.941 1.00 37.43 ? 741 HOH A O 1 741 ? ? ? ?
HETATM 2094 O O . HOH N 4 . ? 23.737 21.296 3.103 1.00 33.70 ? 742 HOH A O 1 742 ? ? ? ?
HETATM 2095 O O . HOH N 4 . ? 26.941 16.978 3.845 1.00 37.25 ? 743 HOH A O 1 743 ? ? ? ?
HETATM 2096 O O . HOH N 4 . ? 16.581 28.621 1.016 1.00 31.51 ? 744 HOH A O 1 744 ? ? ? ?
HETATM 2097 O O . HOH N 4 . ? 0.169 -2.044 25.370 1.00 31.93 ? 745 HOH A O 1 745 ? ? ? ?
HETATM 2098 O O . HOH N 4 . ? -0.894 30.070 35.234 1.00 27.27 ? 746 HOH A O 1 746 ? ? ? ?
HETATM 2099 O O . HOH N 4 . ? 1.258 28.235 36.382 1.00 24.21 ? 747 HOH A O 1 747 ? ? ? ?
HETATM 2100 O O . HOH N 4 . ? -0.335 0.037 30.257 1.00 21.67 ? 748 HOH A O 1 748 ? ? ? ?
HETATM 2101 O O . HOH N 4 . ? 5.323 23.700 -5.621 1.00 31.54 ? 749 HOH A O 1 749 ? ? ? ?
HETATM 2102 O O . HOH N 4 . ? -6.901 12.114 10.675 1.00 32.71 ? 750 HOH A O 1 750 ? ? ? ?
HETATM 2103 O O . HOH N 4 . ? 34.407 8.475 29.273 1.00 38.44 ? 751 HOH A O 1 751 ? ? ? ?
HETATM 2104 O O . HOH N 4 . ? 39.729 11.232 25.427 1.00 35.40 ? 752 HOH A O 1 752 ? ? ? ?
HETATM 2105 O O . HOH N 4 . ? 31.410 10.984 23.749 1.00 38.60 ? 753 HOH A O 1 753 ? ? ? ?
HETATM 2106 O O . HOH N 4 . ? 36.512 8.182 26.669 1.00 38.00 ? 754 HOH A O 1 754 ? ? ? ?
HETATM 2107 O O . HOH N 4 . ? 31.127 17.088 28.744 1.00 33.32 ? 755 HOH A O 1 755 ? ? ? ?
HETATM 2108 O O . HOH N 4 . ? 26.898 23.173 28.464 1.00 35.51 ? 756 HOH A O 1 756 ? ? ? ?
HETATM 2109 O O . HOH N 4 . ? 29.474 18.990 14.698 1.00 38.19 ? 757 HOH A O 1 757 ? ? ? ?
HETATM 2110 O O . HOH N 4 . ? 28.193 16.855 20.019 1.00 36.19 ? 758 HOH A O 1 758 ? ? ? ?
HETATM 2111 O O . HOH N 4 . ? 26.045 22.435 6.092 1.00 36.35 ? 759 HOH A O 1 759 ? ? ? ?
HETATM 2112 O O . HOH N 4 . ? 29.099 19.420 12.081 1.00 36.87 ? 760 HOH A O 1 760 ? ? ? ?
HETATM 2113 O O . HOH N 4 . ? 27.463 26.756 9.512 1.00 33.00 ? 761 HOH A O 1 761 ? ? ? ?
HETATM 2114 O O . HOH N 4 . ? 19.825 25.305 36.982 1.00 40.03 ? 762 HOH A O 1 762 ? ? ? ?
HETATM 2115 O O . HOH N 4 . ? 38.398 25.130 37.361 1.00 34.62 ? 763 HOH A O 1 763 ? ? ? ?
HETATM 2116 O O . HOH N 4 . ? 3.271 3.478 5.769 1.00 32.40 ? 764 HOH A O 1 764 ? ? ? ?
HETATM 2117 O O . HOH N 4 . ? 10.568 5.018 0.404 1.00 24.85 ? 765 HOH A O 1 765 ? ? ? ?
HETATM 2118 O O . HOH N 4 . ? 2.705 3.774 2.995 1.00 38.80 ? 766 HOH A O 1 766 ? ? ? ?
HETATM 2119 O O . HOH N 4 . ? 2.157 0.593 7.081 1.00 36.04 ? 767 HOH A O 1 767 ? ? ? ?
HETATM 2120 O O . HOH N 4 . ? 2.618 8.152 9.998 1.00 22.70 ? 768 HOH A O 1 768 ? ? ? ?
HETATM 2121 O O . HOH N 4 . ? 7.857 13.535 -2.074 1.00 30.02 ? 769 HOH A O 1 769 ? ? ? ?
HETATM 2122 O O . HOH N 4 . ? -5.156 -2.029 15.768 1.00 42.25 ? 770 HOH A O 1 770 ? ? ? ?
HETATM 2123 O O . HOH N 4 . ? 1.787 20.730 32.063 1.00 24.07 ? 771 HOH A O 1 771 ? ? ? ?
HETATM 2124 O O . HOH N 4 . ? -2.868 23.612 33.040 1.00 31.55 ? 772 HOH A O 1 772 ? ? ? ?
HETATM 2125 O O . HOH N 4 . ? 6.879 17.963 40.887 1.00 34.96 ? 773 HOH A O 1 773 ? ? ? ?
HETATM 2126 O O . HOH N 4 . ? -2.024 8.629 33.419 1.00 33.98 ? 774 HOH A O 1 774 ? ? ? ?
HETATM 2127 O O . HOH N 4 . ? -3.517 15.566 38.248 1.00 39.06 ? 775 HOH A O 1 775 ? ? ? ?
HETATM 2128 O O . HOH N 4 . ? -5.300 19.396 35.049 1.00 37.56 ? 776 HOH A O 1 776 ? ? ? ?
HETATM 2129 O O . HOH N 4 . ? -3.172 0.853 23.223 1.00 34.31 ? 777 HOH A O 1 777 ? ? ? ?
HETATM 2130 O O . HOH N 4 . ? 28.072 19.441 39.904 1.00 41.22 ? 778 HOH A O 1 778 ? ? ? ?
HETATM 2131 O O . HOH N 4 . ? 26.272 15.877 42.765 1.00 37.13 ? 779 HOH A O 1 779 ? ? ? ?
HETATM 2132 O O . HOH N 4 . ? 26.033 15.546 45.222 1.00 40.09 ? 780 HOH A O 1 780 ? ? ? ?
HETATM 2133 O O . HOH N 4 . ? 22.987 15.590 36.630 1.00 36.96 ? 781 HOH A O 1 781 ? ? ? ?
HETATM 2134 O O . HOH N 4 . ? 29.884 14.515 32.251 1.00 37.71 ? 782 HOH A O 1 782 ? ? ? ?
HETATM 2135 O O . HOH N 4 . ? 33.070 29.295 35.265 1.00 35.65 ? 783 HOH A O 1 783 ? ? ? ?
HETATM 2136 O O . HOH N 4 . ? 29.248 16.030 23.950 1.00 32.02 ? 784 HOH A O 1 784 ? ? ? ?
HETATM 2137 O O . HOH N 4 . ? 30.134 20.059 23.539 1.00 38.80 ? 785 HOH A O 1 785 ? ? ? ?
HETATM 2138 O O . HOH N 4 . ? 29.187 11.313 20.756 1.00 25.77 ? 786 HOH A O 1 786 ? ? ? ?
HETATM 2139 O O . HOH N 4 . ? 35.902 17.788 15.527 1.00 37.00 ? 787 HOH A O 1 787 ? ? ? ?
HETATM 2140 O O . HOH N 4 . ? 32.435 21.181 16.580 1.00 37.26 ? 788 HOH A O 1 788 ? ? ? ?
HETATM 2141 O O . HOH N 4 . ? 32.900 15.203 14.987 1.00 37.68 ? 789 HOH A O 1 789 ? ? ? ?
HETATM 2142 O O . HOH N 4 . ? 30.896 14.578 16.251 1.00 40.51 ? 790 HOH A O 1 790 ? ? ? ?
HETATM 2143 O O . HOH N 4 . ? 10.513 6.103 40.459 1.00 36.87 ? 791 HOH A O 1 791 ? ? ? ?
HETATM 2144 O O . HOH N 4 . ? 12.627 6.065 37.015 1.00 38.68 ? 792 HOH A O 1 792 ? ? ? ?
HETATM 2145 O O . HOH N 4 . ? 14.603 8.235 36.819 1.00 36.13 ? 793 HOH A O 1 793 ? ? ? ?
HETATM 2146 O O . HOH N 4 . ? 8.084 0.904 40.419 1.00 36.52 ? 794 HOH A O 1 794 ? ? ? ?
HETATM 2147 O O . HOH N 4 . ? 9.571 9.173 43.407 1.00 40.19 ? 795 HOH A O 1 795 ? ? ? ?
HETATM 2148 O O . HOH N 4 . ? 5.348 9.412 39.952 1.00 40.55 ? 796 HOH A O 1 796 ? ? ? ?
HETATM 2149 O O . HOH N 4 . ? -0.164 14.456 45.566 1.00 38.60 ? 797 HOH A O 1 797 ? ? ? ?
HETATM 2150 O O . HOH N 4 . ? -16.538 24.428 10.029 1.00 35.54 ? 798 HOH A O 1 798 ? ? ? ?
HETATM 2151 O O . HOH N 4 . ? -13.611 18.699 4.012 1.00 33.08 ? 799 HOH A O 1 799 ? ? ? ?
HETATM 2152 O O . HOH N 4 . ? 20.750 -0.688 30.659 1.00 36.38 ? 800 HOH A O 1 800 ? ? ? ?
HETATM 2153 O O . HOH N 4 . ? 29.791 3.776 25.455 1.00 35.68 ? 801 HOH A O 1 801 ? ? ? ?
HETATM 2154 O O . HOH N 4 . ? -0.542 35.100 13.142 1.00 33.11 ? 802 HOH A O 1 802 ? ? ? ?
HETATM 2155 O O . HOH N 4 . ? -4.402 6.624 32.797 1.00 11.91 ? 803 HOH A O 1 803 ? ? ? ?
HETATM 2156 O O . HOH N 4 . ? 3.118 34.603 13.448 1.00 29.35 ? 804 HOH A O 1 804 ? ? ? ?
HETATM 2157 O O . HOH N 4 . ? 8.326 25.632 -5.238 1.00 41.12 ? 805 HOH A O 1 805 ? ? ? ?
HETATM 2158 O O . HOH N 4 . ? 20.215 23.105 6.559 1.00 26.99 ? 806 HOH A O 1 806 ? ? ? ?
HETATM 2159 O O . HOH N 4 . ? -9.756 12.173 9.497 1.00 37.32 ? 807 HOH A O 1 807 ? ? ? ?
HETATM 2160 O O . HOH N 4 . ? -19.360 17.488 37.838 1.00 36.57 ? 808 HOH A O 1 808 ? ? ? ?
HETATM 2161 O O . HOH N 4 . ? 6.874 -5.296 24.885 1.00 36.71 ? 809 HOH A O 1 809 ? ? ? ?
HETATM 2162 O O . HOH N 4 . ? -0.625 34.750 26.266 1.00 38.29 ? 810 HOH A O 1 810 ? ? ? ?
HETATM 2163 O O . HOH N 4 . ? 11.582 -0.277 3.410 1.00 36.99 ? 811 HOH A O 1 811 ? ? ? ?
HETATM 2164 O O . HOH N 4 . ? -0.181 22.352 33.528 1.00 33.52 ? 812 HOH A O 1 812 ? ? ? ?
HETATM 2165 O O . HOH N 4 . ? -1.323 23.760 35.066 1.00 36.93 ? 813 HOH A O 1 813 ? ? ? ?
HETATM 2166 O O . HOH N 4 . ? 11.269 29.793 4.714 1.00 29.45 ? 814 HOH A O 1 814 ? ? ? ?
HETATM 2167 O O . HOH N 4 . ? 9.055 0.057 8.438 1.00 34.85 ? 815 HOH A O 1 815 ? ? ? ?
HETATM 2168 O O . HOH N 4 . ? -8.612 32.366 24.329 1.00 28.65 ? 816 HOH A O 1 816 ? ? ? ?
HETATM 2169 O O . HOH N 4 . ? 2.717 33.306 24.518 1.00 38.07 ? 817 HOH A O 1 817 ? ? ? ?
HETATM 2170 O O . HOH N 4 . ? 0.521 32.659 25.209 1.00 37.77 ? 818 HOH A O 1 818 ? ? ? ?
HETATM 2171 O O . HOH N 4 . ? 7.310 24.505 32.456 1.00 26.44 ? 819 HOH A O 1 819 ? ? ? ?
HETATM 2172 O O . HOH N 4 . ? 8.107 24.651 35.352 1.00 24.86 ? 820 HOH A O 1 820 ? ? ? ?
HETATM 2173 O O . HOH N 4 . ? 26.033 4.938 32.073 1.00 34.33 ? 821 HOH A O 1 821 ? ? ? ?
HETATM 2174 O O . HOH N 4 . ? 8.944 35.097 12.437 1.00 26.36 ? 822 HOH A O 1 822 ? ? ? ?
HETATM 2175 O O . HOH N 4 . ? 6.142 36.848 16.788 1.00 18.80 ? 823 HOH A O 1 823 ? ? ? ?
HETATM 2176 O O . HOH N 4 . ? 5.666 36.025 14.791 1.00 33.93 ? 824 HOH A O 1 824 ? ? ? ?
HETATM 2177 O O . HOH N 4 . ? -7.949 30.410 4.887 1.00 36.81 ? 825 HOH A O 1 825 ? ? ? ?
HETATM 2178 O O . HOH N 4 . ? -6.041 16.814 29.146 1.00 40.97 ? 826 HOH A O 1 826 ? ? ? ?
HETATM 2179 O O . HOH N 4 . ? -3.052 20.438 29.459 1.00 14.31 ? 827 HOH A O 1 827 ? ? ? ?
HETATM 2180 O O . HOH N 4 . ? 12.776 1.538 3.528 1.00 33.31 ? 828 HOH A O 1 828 ? ? ? ?
HETATM 2181 O O . HOH N 4 . ? 11.676 -1.729 1.523 1.00 40.91 ? 829 HOH A O 1 829 ? ? ? ?
HETATM 2182 O O . HOH N 4 . ? 15.490 24.183 33.896 1.00 29.89 ? 830 HOH A O 1 830 ? ? ? ?
HETATM 2183 O O . HOH N 4 . ? 20.213 27.811 36.511 1.00 36.93 ? 831 HOH A O 1 831 ? ? ? ?
HETATM 2184 O O . HOH N 4 . ? -4.783 4.231 13.491 1.00 36.01 ? 832 HOH A O 1 832 ? ? ? ?
HETATM 2185 O O . HOH N 4 . ? -4.283 7.865 14.249 1.00 30.05 ? 833 HOH A O 1 833 ? ? ? ?
HETATM 2186 O O . HOH N 4 . ? 2.439 -0.410 19.273 1.00 32.19 ? 834 HOH A O 1 834 ? ? ? ?
HETATM 2187 O O . HOH N 4 . ? 12.103 21.117 -1.832 1.00 30.60 ? 835 HOH A O 1 835 ? ? ? ?
HETATM 2188 O O . HOH N 4 . ? -1.039 28.863 1.379 1.00 16.25 ? 836 HOH A O 1 836 ? ? ? ?
HETATM 2189 O O . HOH N 4 . ? -1.447 29.407 37.518 1.00 21.36 ? 837 HOH A O 1 837 ? ? ? ?
HETATM 2190 O O . HOH N 4 . ? -12.628 35.172 17.822 1.00 39.97 ? 838 HOH A O 1 838 ? ? ? ?
HETATM 2191 O O . HOH N 4 . ? -11.133 40.550 12.025 1.00 36.22 ? 839 HOH A O 1 839 ? ? ? ?
HETATM 2192 O O . HOH N 4 . ? -10.271 42.024 14.700 1.00 33.89 ? 840 HOH A O 1 840 ? ? ? ?
HETATM 2193 O O . HOH N 4 . ? -11.226 8.615 20.619 1.00 35.37 ? 841 HOH A O 1 841 ? ? ? ?
HETATM 2194 O O . HOH N 4 . ? 1.402 9.911 9.054 1.00 31.00 ? 843 HOH A O 1 843 ? ? ? ?
HETATM 2195 O O . HOH N 4 . ? -1.440 32.993 12.080 1.00 27.18 ? 844 HOH A O 1 844 ? ? ? ?
HETATM 2196 O O . HOH N 4 . ? 39.764 11.354 29.454 1.00 37.52 ? 845 HOH A O 1 845 ? ? ? ?
HETATM 2197 O O . HOH N 4 . ? 5.930 2.519 8.928 1.00 40.02 ? 846 HOH A O 1 846 ? ? ? ?
HETATM 2198 O O . HOH N 4 . ? 3.354 6.160 5.788 1.00 37.04 ? 847 HOH A O 1 847 ? ? ? ?
HETATM 2199 O O . HOH N 4 . ? -2.639 0.754 19.018 1.00 33.82 ? 848 HOH A O 1 848 ? ? ? ?
HETATM 2200 O O . HOH N 4 . ? -22.133 22.006 18.124 1.00 35.15 ? 849 HOH A O 1 849 ? ? ? ?
HETATM 2201 O O . HOH N 4 . ? -17.554 19.208 23.404 1.00 33.43 ? 850 HOH A O 1 850 ? ? ? ?
HETATM 2202 O O . HOH N 4 . ? -9.630 10.052 30.279 1.00 36.24 ? 851 HOH A O 1 851 ? ? ? ?
HETATM 2203 O O . HOH N 4 . ? -7.327 7.354 28.057 1.00 34.19 ? 852 HOH A O 1 852 ? ? ? ?
HETATM 2204 O O . HOH N 4 . ? 18.093 9.345 36.092 1.00 36.42 ? 854 HOH A O 1 854 ? ? ? ?
HETATM 2205 O O . HOH N 4 . ? 14.871 12.319 36.036 1.00 39.29 ? 855 HOH A O 1 855 ? ? ? ?
HETATM 2206 O O . HOH N 4 . ? 15.572 9.055 34.577 1.00 35.54 ? 856 HOH A O 1 856 ? ? ? ?
HETATM 2207 O O . HOH N 4 . ? 10.741 7.612 35.954 1.00 36.25 ? 857 HOH A O 1 857 ? ? ? ?
HETATM 2208 O O . HOH N 4 . ? 6.677 11.248 40.764 1.00 35.75 ? 858 HOH A O 1 858 ? ? ? ?
HETATM 2209 O O . HOH N 4 . ? 8.371 4.919 38.879 1.00 37.11 ? 859 HOH A O 1 859 ? ? ? ?
HETATM 2210 O O . HOH N 4 . ? 6.023 2.975 38.260 1.00 38.87 ? 860 HOH A O 1 860 ? ? ? ?
HETATM 2211 O O . HOH N 4 . ? -1.741 -0.152 25.614 1.00 29.79 ? 861 HOH A O 1 861 ? ? ? ?
HETATM 2212 O O . HOH N 4 . ? 4.835 -4.151 26.077 1.00 29.67 ? 862 HOH A O 1 862 ? ? ? ?
HETATM 2213 O O . HOH N 4 . ? 27.128 23.719 17.248 1.00 36.02 ? 863 HOH A O 1 863 ? ? ? ?
HETATM 2214 O O . HOH N 4 . ? 27.200 19.047 21.358 1.00 36.82 ? 864 HOH A O 1 864 ? ? ? ?
HETATM 2215 O O . HOH N 4 . ? 32.818 20.431 22.741 1.00 38.98 ? 865 HOH A O 1 865 ? ? ? ?
HETATM 2216 O O . HOH N 4 . ? 31.356 9.110 17.961 1.00 36.96 ? 866 HOH A O 1 866 ? ? ? ?
HETATM 2217 O O . HOH N 4 . ? 32.419 15.081 18.008 1.00 37.64 ? 867 HOH A O 1 867 ? ? ? ?
HETATM 2218 O O . HOH N 4 . ? 29.665 13.865 23.220 1.00 35.75 ? 868 HOH A O 1 868 ? ? ? ?
HETATM 2219 O O . HOH N 4 . ? 27.597 15.368 13.173 1.00 37.43 ? 869 HOH A O 1 869 ? ? ? ?
HETATM 2220 O O . HOH N 4 . ? 30.679 15.044 13.853 1.00 38.55 ? 870 HOH A O 1 870 ? ? ? ?
HETATM 2221 O O . HOH N 4 . ? 0.962 -2.493 18.073 1.00 39.85 ? 871 HOH A O 1 871 ? ? ? ?
HETATM 2222 O O . HOH N 4 . ? -4.458 -5.157 13.255 1.00 37.87 ? 872 HOH A O 1 872 ? ? ? ?
HETATM 2223 O O . HOH N 4 . ? -0.303 12.486 42.183 1.00 34.86 ? 873 HOH A O 1 873 ? ? ? ?
HETATM 2224 O O . HOH N 4 . ? -17.151 25.473 12.564 1.00 37.86 ? 874 HOH A O 1 874 ? ? ? ?
HETATM 2225 O O . HOH N 4 . ? -16.674 18.678 18.407 1.00 38.09 ? 875 HOH A O 1 875 ? ? ? ?
HETATM 2226 O O . HOH N 4 . ? -15.954 24.239 18.524 1.00 39.35 ? 876 HOH A O 1 876 ? ? ? ?
HETATM 2227 O O . HOH N 4 . ? -16.546 22.114 16.734 1.00 30.20 ? 877 HOH A O 1 877 ? ? ? ?
HETATM 2228 O O . HOH N 4 . ? -13.858 10.662 25.305 1.00 39.33 ? 878 HOH A O 1 878 ? ? ? ?
HETATM 2229 O O . HOH N 4 . ? -12.049 15.374 21.173 1.00 29.22 ? 879 HOH A O 1 879 ? ? ? ?
HETATM 2230 O O . HOH N 4 . ? -11.399 12.320 23.189 1.00 40.50 ? 880 HOH A O 1 880 ? ? ? ?
HETATM 2231 O O . HOH N 4 . ? -9.970 7.578 26.215 1.00 34.18 ? 881 HOH A O 1 881 ? ? ? ?
HETATM 2232 O O . HOH N 4 . ? 6.581 27.045 -4.193 1.00 35.02 ? 882 HOH A O 1 882 ? ? ? ?
HETATM 2233 O O . HOH N 4 . ? 8.903 26.606 0.786 1.00 28.51 ? 883 HOH A O 1 883 ? ? ? ?
HETATM 2234 O O . HOH N 4 . ? 4.395 28.305 -0.048 1.00 34.86 ? 884 HOH A O 1 884 ? ? ? ?
HETATM 2235 O O . HOH N 4 . ? 1.285 29.212 2.801 1.00 35.56 ? 885 HOH A O 1 885 ? ? ? ?
HETATM 2236 O O . HOH N 4 . ? 24.607 0.843 34.810 1.00 34.63 ? 886 HOH A O 1 886 ? ? ? ?
HETATM 2237 O O . HOH N 4 . ? -8.320 34.636 17.145 1.00 35.84 ? 887 HOH A O 1 887 ? ? ? ?
HETATM 2238 O O . HOH N 4 . ? -11.649 31.713 16.059 1.00 34.56 ? 888 HOH A O 1 888 ? ? ? ?
HETATM 2239 O O . HOH N 4 . ? -14.388 37.262 11.362 1.00 40.90 ? 889 HOH A O 1 889 ? ? ? ?
HETATM 2240 O O . HOH N 4 . ? -12.598 35.756 15.164 1.00 36.59 ? 890 HOH A O 1 890 ? ? ? ?
HETATM 2241 O O . HOH N 4 . ? -11.685 37.036 19.266 1.00 37.78 ? 891 HOH A O 1 891 ? ? ? ?
HETATM 2242 O O . HOH N 4 . ? -13.121 39.645 15.049 1.00 40.25 ? 892 HOH A O 1 892 ? ? ? ?
HETATM 2243 O O . HOH N 4 . ? -7.857 37.983 21.725 1.00 33.49 ? 893 HOH A O 1 893 ? ? ? ?
HETATM 2244 O O . HOH N 4 . ? -5.235 36.756 27.320 1.00 33.38 ? 894 HOH A O 1 894 ? ? ? ?
HETATM 2245 O O . HOH N 4 . ? -0.616 38.770 25.775 1.00 40.89 ? 895 HOH A O 1 895 ? ? ? ?
HETATM 2246 O O . HOH N 4 . ? -0.629 36.879 27.083 1.00 37.76 ? 896 HOH A O 1 896 ? ? ? ?
HETATM 2247 O O . HOH N 4 . ? 5.306 33.908 23.128 1.00 33.85 ? 897 HOH A O 1 897 ? ? ? ?
HETATM 2248 O O . HOH N 4 . ? -3.073 34.016 7.771 1.00 36.26 ? 898 HOH A O 1 898 ? ? ? ?
HETATM 2249 O O . HOH N 4 . ? 34.534 8.191 25.338 1.00 38.12 ? 899 HOH A O 1 899 ? ? ? ?
HETATM 2250 O O . HOH N 4 . ? 42.251 12.025 28.757 1.00 37.91 ? 900 HOH A O 1 900 ? ? ? ?
HETATM 2251 O O . HOH N 4 . ? 42.592 9.409 24.564 1.00 38.69 ? 901 HOH A O 1 901 ? ? ? ?
HETATM 2252 O O . HOH N 4 . ? -8.107 18.788 31.803 1.00 36.08 ? 902 HOH A O 1 902 ? ? ? ?
HETATM 2253 O O . HOH N 4 . ? 2.723 20.842 34.009 1.00 33.04 ? 903 HOH A O 1 903 ? ? ? ?
HETATM 2254 O O . HOH N 4 . ? 14.915 27.793 28.229 1.00 6.73 ? 904 HOH A O 1 904 ? ? ? ?
HETATM 2255 O O . HOH N 4 . ? 21.461 11.112 38.234 1.00 37.29 ? 905 HOH A O 1 905 ? ? ? ?
HETATM 2256 O O . HOH N 4 . ? 29.408 21.409 31.153 1.00 38.55 ? 906 HOH A O 1 906 ? ? ? ?
HETATM 2257 O O . HOH N 4 . ? 29.202 25.710 28.412 1.00 37.14 ? 907 HOH A O 1 907 ? ? ? ?
HETATM 2258 O O . HOH N 4 . ? 30.706 18.608 33.188 1.00 36.14 ? 908 HOH A O 1 908 ? ? ? ?
HETATM 2259 O O . HOH N 4 . ? 27.980 20.088 33.514 1.00 37.47 ? 909 HOH A O 1 909 ? ? ? ?
HETATM 2260 O O . HOH N 4 . ? 31.084 20.057 37.867 1.00 36.22 ? 910 HOH A O 1 910 ? ? ? ?
HETATM 2261 O O . HOH N 4 . ? 36.257 24.138 40.522 1.00 40.33 ? 911 HOH A O 1 911 ? ? ? ?
HETATM 2262 O O . HOH N 4 . ? 27.852 22.014 42.208 1.00 38.58 ? 912 HOH A O 1 912 ? ? ? ?
HETATM 2263 O O . HOH N 4 . ? 31.928 22.537 42.018 1.00 38.36 ? 913 HOH A O 1 913 ? ? ? ?
HETATM 2264 O O . HOH N 4 . ? 26.480 6.527 29.443 1.00 34.82 ? 914 HOH A O 1 914 ? ? ? ?
HETATM 2265 O O . HOH N 4 . ? -6.754 28.043 30.415 1.00 29.28 ? 915 HOH A O 1 915 ? ? ? ?
HETATM 2266 O O . HOH N 4 . ? -4.648 27.503 33.625 1.00 30.58 ? 916 HOH A O 1 916 ? ? ? ?
HETATM 2267 O O . HOH N 4 . ? 13.652 4.212 2.358 1.00 34.43 ? 917 HOH A O 1 917 ? ? ? ?
HETATM 2268 O O . HOH N 4 . ? 8.171 3.043 7.281 1.00 38.44 ? 920 HOH A O 1 920 ? ? ? ?
HETATM 2269 O O . HOH N 4 . ? 2.942 -0.648 8.997 1.00 36.49 ? 921 HOH A O 1 921 ? ? ? ?
HETATM 2270 O O . HOH N 4 . ? 4.613 1.443 6.310 1.00 36.67 ? 922 HOH A O 1 922 ? ? ? ?
HETATM 2271 O O . HOH N 4 . ? -0.478 4.486 6.731 1.00 40.22 ? 923 HOH A O 1 923 ? ? ? ?
HETATM 2272 O O . HOH N 4 . ? -2.788 5.267 9.662 1.00 35.54 ? 924 HOH A O 1 924 ? ? ? ?
HETATM 2273 O O . HOH N 4 . ? -15.648 26.220 28.894 1.00 34.85 ? 925 HOH A O 1 925 ? ? ? ?
HETATM 2274 O O . HOH N 4 . ? -18.501 23.355 34.958 1.00 38.67 ? 926 HOH A O 1 926 ? ? ? ?
HETATM 2275 O O . HOH N 4 . ? -5.281 -5.225 1.219 1.00 39.35 ? 927 HOH A O 1 927 ? ? ? ?
HETATM 2276 O O . HOH N 4 . ? -22.864 17.734 22.383 1.00 37.77 ? 928 HOH A O 1 928 ? ? ? ?
HETATM 2277 O O . HOH N 4 . ? -20.502 13.558 22.895 1.00 35.66 ? 929 HOH A O 1 929 ? ? ? ?
HETATM 2278 O O . HOH N 4 . ? -4.189 7.836 36.682 1.00 40.84 ? 930 HOH A O 1 930 ? ? ? ?
HETATM 2279 O O . HOH O 4 . ? 7.563 9.180 5.485 1.00 16.06 ? 412 HOH B O 1 412 ? ? ? ?
HETATM 2280 O O . HOH O 4 . ? 4.657 10.385 8.417 1.00 13.14 ? 413 HOH B O 1 413 ? ? ? ?
HETATM 2281 O O . HOH O 4 . ? 12.213 13.109 5.803 1.00 8.70 ? 494 HOH B O 1 494 ? ? ? ?
HETATM 2282 O O . HOH O 4 . ? 4.239 6.654 8.068 1.00 26.27 ? 525 HOH B O 1 525 ? ? ? ?
HETATM 2283 O O . HOH O 4 . ? 6.458 8.435 7.618 1.00 16.37 ? 682 HOH B O 1 682 ? ? ? ?
HETATM 2284 O O . HOH O 4 . ? 5.399 8.554 9.603 1.00 25.25 ? 842 HOH B O 1 842 ? ? ? ?
HETATM 2285 O O . HOH O 4 . ? 11.306 11.310 0.010 0.50 33.46 ? 853 HOH B O 1 853 ? ? ? ?
HETATM 2286 O O . HOH O 4 . ? 8.190 5.908 2.594 1.00 32.35 ? 918 HOH B O 1 918 ? ? ? ?
HETATM 2287 O O . HOH O 4 . ? 7.396 3.288 0.585 1.00 38.94 ? 919 HOH B O 1 919 ? ? ? ?
#
_pdbx_sifts_unp_segments.entity_id 1
_pdbx_sifts_unp_segments.asym_id A
_pdbx_sifts_unp_segments.unp_acc O57413
_pdbx_sifts_unp_segments.segment_id 1
_pdbx_sifts_unp_segments.instance_id 1
_pdbx_sifts_unp_segments.unp_start 190
_pdbx_sifts_unp_segments.unp_end 392
_pdbx_sifts_unp_segments.seq_id_start 1
_pdbx_sifts_unp_segments.seq_id_end 203
_pdbx_sifts_unp_segments.best_mapping y
_pdbx_sifts_unp_segments.identity 0.99
#
loop_
_pdbx_sifts_xref_db_segments.entity_id
_pdbx_sifts_xref_db_segments.asym_id
_pdbx_sifts_xref_db_segments.xref_db
_pdbx_sifts_xref_db_segments.xref_db_acc
_pdbx_sifts_xref_db_segments.domain_name
_pdbx_sifts_xref_db_segments.segment_id
_pdbx_sifts_xref_db_segments.instance_id
_pdbx_sifts_xref_db_segments.seq_id_start
_pdbx_sifts_xref_db_segments.seq_id_end
1 A CATH 3.40.390.10 1kugA00 1 1 3 203
1 A SCOP2B 8040594 SF 1 1 3 203
1 A Pfam PF01421 ? 1 1 8 203
#
loop_
_pdbx_sifts_xref_db.entity_id
_pdbx_sifts_xref_db.asym_id
_pdbx_sifts_xref_db.seq_id_ordinal
_pdbx_sifts_xref_db.seq_id
_pdbx_sifts_xref_db.mon_id
_pdbx_sifts_xref_db.mon_id_one_letter_code
_pdbx_sifts_xref_db.unp_res
_pdbx_sifts_xref_db.unp_num
_pdbx_sifts_xref_db.unp_acc
_pdbx_sifts_xref_db.unp_segment_id
_pdbx_sifts_xref_db.unp_instance_id
_pdbx_sifts_xref_db.res_type
_pdbx_sifts_xref_db.observed
_pdbx_sifts_xref_db.mh_id
_pdbx_sifts_xref_db.xref_db_name
_pdbx_sifts_xref_db.xref_db_acc
_pdbx_sifts_xref_db.xref_domain_name
_pdbx_sifts_xref_db.xref_db_segment_id
_pdbx_sifts_xref_db.xref_db_instance_id
1 A 1 1 GLU E E 190 O57413 1 1 ? n 1 ? ? ? ? ?
1 A 1 2 GLN Q Q 191 O57413 1 1 ? n 1 ? ? ? ? ?
1 A 1 3 GLN Q Q 192 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 2 3 GLN Q Q 192 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 4 ARG R R 193 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 2 4 ARG R R 193 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 5 PHE F F 194 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 2 5 PHE F F 194 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 6 PRO P P 195 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 2 6 PRO P P 195 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 7 GLN Q Q 196 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 2 7 GLN Q Q 196 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 8 ARG R R 197 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 8 ARG R R 197 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 8 ARG R R 197 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 9 TYR Y Y 198 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 9 TYR Y Y 198 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 9 TYR Y Y 198 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 10 ILE I I 199 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 10 ILE I I 199 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 10 ILE I I 199 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 11 GLU E K 200 O57413 1 1 Conflict y 1 Pfam PF01421 ? 1 1
1 A 2 11 GLU E K 200 O57413 1 1 Conflict y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 11 GLU E K 200 O57413 1 1 Conflict y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 12 LEU L L 201 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 12 LEU L L 201 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 12 LEU L L 201 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 13 ALA A A 202 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 13 ALA A A 202 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 13 ALA A A 202 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 14 ILE I I 203 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 14 ILE I I 203 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 14 ILE I I 203 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 15 VAL V V 204 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 15 VAL V V 204 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 15 VAL V V 204 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 16 VAL V V 205 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 16 VAL V V 205 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 16 VAL V V 205 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 17 ASP D D 206 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 17 ASP D D 206 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 17 ASP D D 206 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 18 HIS H H 207 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 18 HIS H H 207 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 18 HIS H H 207 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 19 GLY G G 208 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 19 GLY G G 208 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 19 GLY G G 208 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 20 MET M M 209 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 20 MET M M 209 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 20 MET M M 209 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 21 TYR Y Y 210 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 21 TYR Y Y 210 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 21 TYR Y Y 210 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 22 THR T T 211 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 22 THR T T 211 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 22 THR T T 211 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 23 LYS K K 212 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 23 LYS K K 212 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 23 LYS K K 212 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 24 TYR Y Y 213 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 24 TYR Y Y 213 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 24 TYR Y Y 213 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 25 SER S S 214 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 25 SER S S 214 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 25 SER S S 214 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 26 SER S S 215 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 26 SER S S 215 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 26 SER S S 215 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 27 ASN N N 216 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 27 ASN N N 216 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 27 ASN N N 216 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 28 PHE F F 217 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 28 PHE F F 217 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 28 PHE F F 217 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 29 LYS K K 218 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 29 LYS K K 218 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 29 LYS K K 218 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 30 LYS K K 219 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 30 LYS K K 219 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 30 LYS K K 219 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 31 ILE I I 220 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 31 ILE I I 220 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 31 ILE I I 220 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 32 ARG R R 221 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 32 ARG R R 221 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 32 ARG R R 221 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 33 LYS K K 222 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 33 LYS K K 222 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 33 LYS K K 222 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 34 ARG R R 223 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 34 ARG R R 223 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 34 ARG R R 223 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 35 VAL V V 224 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 35 VAL V V 224 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 35 VAL V V 224 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 36 HIS H H 225 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 36 HIS H H 225 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 36 HIS H H 225 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 37 GLN Q Q 226 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 37 GLN Q Q 226 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 37 GLN Q Q 226 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 38 MET M M 227 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 38 MET M M 227 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 38 MET M M 227 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 39 VAL V V 228 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 39 VAL V V 228 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 39 VAL V V 228 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 40 SER S S 229 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 40 SER S S 229 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 40 SER S S 229 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 41 ASN N N 230 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 41 ASN N N 230 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 41 ASN N N 230 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 42 ILE I I 231 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 42 ILE I I 231 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 42 ILE I I 231 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 43 ASN N N 232 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 43 ASN N N 232 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 43 ASN N N 232 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 44 GLU E E 233 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 44 GLU E E 233 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 44 GLU E E 233 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 45 MET M M 234 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 45 MET M M 234 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 45 MET M M 234 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 46 CYS C C 235 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 46 CYS C C 235 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 46 CYS C C 235 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 47 ARG R R 236 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 47 ARG R R 236 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 47 ARG R R 236 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 48 PRO P P 237 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 48 PRO P P 237 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 48 PRO P P 237 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 49 LEU L L 238 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 49 LEU L L 238 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 49 LEU L L 238 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 50 ASN N N 239 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 50 ASN N N 239 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 50 ASN N N 239 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 51 ILE I I 240 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 51 ILE I I 240 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 51 ILE I I 240 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 52 ALA A A 241 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 52 ALA A A 241 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 52 ALA A A 241 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 53 ILE I I 242 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 53 ILE I I 242 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 53 ILE I I 242 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 54 THR T T 243 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 54 THR T T 243 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 54 THR T T 243 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 55 LEU L L 244 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 55 LEU L L 244 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 55 LEU L L 244 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 56 ALA A A 245 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 56 ALA A A 245 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 56 ALA A A 245 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 57 LEU L L 246 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 57 LEU L L 246 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 57 LEU L L 246 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 58 LEU L L 247 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 58 LEU L L 247 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 58 LEU L L 247 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 59 ASP D D 248 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 59 ASP D D 248 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 59 ASP D D 248 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 60 VAL V V 249 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 60 VAL V V 249 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 60 VAL V V 249 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 61 TRP W W 250 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 61 TRP W W 250 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 61 TRP W W 250 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 62 SER S S 251 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 62 SER S S 251 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 62 SER S S 251 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 63 GLU E E 252 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 63 GLU E E 252 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 63 GLU E E 252 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 64 LYS K K 253 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 64 LYS K K 253 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 64 LYS K K 253 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 65 ASP D D 254 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 65 ASP D D 254 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 65 ASP D D 254 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 66 PHE F F 255 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 66 PHE F F 255 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 66 PHE F F 255 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 67 ILE I I 256 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 67 ILE I I 256 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 67 ILE I I 256 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 68 THR T T 257 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 68 THR T T 257 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 68 THR T T 257 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 69 VAL V V 258 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 69 VAL V V 258 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 69 VAL V V 258 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 70 GLN Q Q 259 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 70 GLN Q Q 259 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 70 GLN Q Q 259 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 71 ALA A A 260 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 71 ALA A A 260 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 71 ALA A A 260 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 72 ASP D D 261 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 72 ASP D D 261 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 72 ASP D D 261 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 73 ALA A A 262 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 73 ALA A A 262 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 73 ALA A A 262 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 74 PRO P P 263 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 74 PRO P P 263 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 74 PRO P P 263 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 75 THR T T 264 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 75 THR T T 264 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 75 THR T T 264 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 76 THR T T 265 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 76 THR T T 265 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 76 THR T T 265 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 77 ALA A A 266 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 77 ALA A A 266 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 77 ALA A A 266 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 78 GLY G G 267 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 78 GLY G G 267 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 78 GLY G G 267 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 79 LEU L L 268 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 79 LEU L L 268 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 79 LEU L L 268 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 80 PHE F F 269 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 80 PHE F F 269 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 80 PHE F F 269 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 81 GLY G G 270 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 81 GLY G G 270 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 81 GLY G G 270 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 82 ASP D D 271 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 82 ASP D D 271 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 82 ASP D D 271 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 83 TRP W W 272 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 83 TRP W W 272 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 83 TRP W W 272 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 84 ARG R R 273 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 84 ARG R R 273 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 84 ARG R R 273 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 85 GLU E E 274 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 85 GLU E E 274 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 85 GLU E E 274 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 86 ARG R R 275 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 86 ARG R R 275 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 86 ARG R R 275 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 87 VAL V V 276 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 87 VAL V V 276 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 87 VAL V V 276 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 88 LEU L L 277 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 88 LEU L L 277 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 88 LEU L L 277 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 89 LEU L L 278 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 89 LEU L L 278 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 89 LEU L L 278 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 90 LYS K K 279 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 90 LYS K K 279 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 90 LYS K K 279 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 91 LYS K K 280 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 91 LYS K K 280 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 91 LYS K K 280 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 92 LYS K K 281 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 92 LYS K K 281 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 92 LYS K K 281 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 93 ASN N N 282 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 93 ASN N N 282 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 93 ASN N N 282 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 94 HIS H H 283 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 94 HIS H H 283 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 94 HIS H H 283 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 95 ASP D D 284 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 95 ASP D D 284 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 95 ASP D D 284 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 96 HIS H H 285 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 96 HIS H H 285 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 96 HIS H H 285 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 97 ALA A A 286 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 97 ALA A A 286 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 97 ALA A A 286 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 98 GLN Q Q 287 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 98 GLN Q Q 287 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 98 GLN Q Q 287 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 99 LEU L L 288 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 99 LEU L L 288 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 99 LEU L L 288 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 100 LEU L L 289 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 100 LEU L L 289 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 100 LEU L L 289 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 101 THR T T 290 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 101 THR T T 290 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 101 THR T T 290 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 102 ASP D D 291 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 102 ASP D D 291 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 102 ASP D D 291 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 103 THR T T 292 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 103 THR T T 292 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 103 THR T T 292 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 104 ASN N N 293 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 104 ASN N N 293 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 104 ASN N N 293 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 105 PHE F F 294 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 105 PHE F F 294 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 105 PHE F F 294 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 106 ALA A A 295 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 106 ALA A A 295 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 106 ALA A A 295 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 107 ARG R R 296 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 107 ARG R R 296 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 107 ARG R R 296 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 108 ASN N N 297 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 108 ASN N N 297 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 108 ASN N N 297 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 109 THR T T 298 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 109 THR T T 298 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 109 THR T T 298 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 110 ILE I I 299 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 110 ILE I I 299 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 110 ILE I I 299 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 111 GLY G G 300 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 111 GLY G G 300 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 111 GLY G G 300 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 112 TRP W W 301 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 112 TRP W W 301 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 112 TRP W W 301 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 113 ALA A A 302 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 113 ALA A A 302 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 113 ALA A A 302 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 114 TYR Y Y 303 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 114 TYR Y Y 303 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 114 TYR Y Y 303 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 115 VAL V V 304 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 115 VAL V V 304 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 115 VAL V V 304 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 116 GLY G G 305 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 116 GLY G G 305 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 116 GLY G G 305 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 117 ARG R R 306 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 117 ARG R R 306 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 117 ARG R R 306 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 118 MET M M 307 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 118 MET M M 307 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 118 MET M M 307 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 119 CYS C C 308 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 119 CYS C C 308 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 119 CYS C C 308 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 120 ASP D D 309 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 120 ASP D D 309 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 120 ASP D D 309 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 121 GLU E E 310 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 121 GLU E E 310 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 121 GLU E E 310 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 122 LYS K K 311 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 122 LYS K K 311 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 122 LYS K K 311 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 123 TYR Y Y 312 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 123 TYR Y Y 312 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 123 TYR Y Y 312 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 124 SER S S 313 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 124 SER S S 313 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 124 SER S S 313 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 125 VAL V V 314 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 125 VAL V V 314 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 125 VAL V V 314 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 126 ALA A A 315 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 126 ALA A A 315 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 126 ALA A A 315 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 127 VAL V V 316 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 127 VAL V V 316 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 127 VAL V V 316 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 128 VAL V V 317 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 128 VAL V V 317 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 128 VAL V V 317 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 129 LYS K K 318 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 129 LYS K K 318 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 129 LYS K K 318 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 130 ASP D D 319 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 130 ASP D D 319 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 130 ASP D D 319 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 131 HIS H H 320 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 131 HIS H H 320 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 131 HIS H H 320 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 132 SER S S 321 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 132 SER S S 321 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 132 SER S S 321 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 133 SER S S 322 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 133 SER S S 322 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 133 SER S S 322 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 134 LYS K K 323 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 134 LYS K K 323 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 134 LYS K K 323 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 135 VAL V V 324 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 135 VAL V V 324 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 135 VAL V V 324 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 136 PHE F F 325 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 136 PHE F F 325 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 136 PHE F F 325 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 137 MET M M 326 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 137 MET M M 326 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 137 MET M M 326 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 138 VAL V V 327 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 138 VAL V V 327 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 138 VAL V V 327 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 139 ALA A A 328 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 139 ALA A A 328 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 139 ALA A A 328 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 140 VAL V V 329 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 140 VAL V V 329 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 140 VAL V V 329 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 141 THR T T 330 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 141 THR T T 330 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 141 THR T T 330 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 142 MET M M 331 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 142 MET M M 331 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 142 MET M M 331 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 143 THR T T 332 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 143 THR T T 332 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 143 THR T T 332 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 144 HIS H H 333 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 144 HIS H H 333 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 144 HIS H H 333 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 145 GLU E E 334 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 145 GLU E E 334 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 145 GLU E E 334 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 146 LEU L L 335 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 146 LEU L L 335 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 146 LEU L L 335 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 147 GLY G G 336 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 147 GLY G G 336 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 147 GLY G G 336 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 148 HIS H H 337 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 148 HIS H H 337 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 148 HIS H H 337 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 149 ASN N N 338 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 149 ASN N N 338 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 149 ASN N N 338 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 150 LEU L L 339 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 150 LEU L L 339 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 150 LEU L L 339 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 151 GLY G G 340 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 151 GLY G G 340 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 151 GLY G G 340 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 152 MET M M 341 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 152 MET M M 341 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 152 MET M M 341 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 153 GLU E E 342 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 153 GLU E E 342 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 153 GLU E E 342 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 154 HIS H H 343 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 154 HIS H H 343 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 154 HIS H H 343 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 155 ASP D D 344 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 155 ASP D D 344 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 155 ASP D D 344 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 156 ASP D D 345 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 156 ASP D D 345 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 156 ASP D D 345 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 157 LYS K K 346 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 157 LYS K K 346 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 157 LYS K K 346 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 158 ASP D D 347 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 158 ASP D D 347 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 158 ASP D D 347 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 159 LYS K K 348 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 159 LYS K K 348 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 159 LYS K K 348 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 160 CYS C C 349 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 160 CYS C C 349 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 160 CYS C C 349 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 161 LYS K K 350 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 161 LYS K K 350 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 161 LYS K K 350 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 162 CYS C C 351 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 162 CYS C C 351 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 162 CYS C C 351 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 163 THR T D 352 O57413 1 1 Conflict y 1 Pfam PF01421 ? 1 1
1 A 2 163 THR T D 352 O57413 1 1 Conflict y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 163 THR T D 352 O57413 1 1 Conflict y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 164 THR T T 353 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 164 THR T T 353 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 164 THR T T 353 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 165 CYS C C 354 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 165 CYS C C 354 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 165 CYS C C 354 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 166 ILE I I 355 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 166 ILE I I 355 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 166 ILE I I 355 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 167 MET M M 356 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 167 MET M M 356 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 167 MET M M 356 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 168 SER S S 357 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 168 SER S S 357 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 168 SER S S 357 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 169 ALA A A 358 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 169 ALA A A 358 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 169 ALA A A 358 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 170 VAL V V 359 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 170 VAL V V 359 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 170 VAL V V 359 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 171 ILE I I 360 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 171 ILE I I 360 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 171 ILE I I 360 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 172 SER S S 361 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 172 SER S S 361 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 172 SER S S 361 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 173 ASP D D 362 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 173 ASP D D 362 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 173 ASP D D 362 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 174 LYS K K 363 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 174 LYS K K 363 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 174 LYS K K 363 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 175 GLN Q Q 364 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 175 GLN Q Q 364 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 175 GLN Q Q 364 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 176 SER S S 365 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 176 SER S S 365 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 176 SER S S 365 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 177 LYS K K 366 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 177 LYS K K 366 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 177 LYS K K 366 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 178 LEU L L 367 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 178 LEU L L 367 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 178 LEU L L 367 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 179 PHE F F 368 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 179 PHE F F 368 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 179 PHE F F 368 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 180 SER S S 369 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 180 SER S S 369 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 180 SER S S 369 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 181 ASP D D 370 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 181 ASP D D 370 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 181 ASP D D 370 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 182 CYS C C 371 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 182 CYS C C 371 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 182 CYS C C 371 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 183 SER S S 372 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 183 SER S S 372 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 183 SER S S 372 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 184 LYS K K 373 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 184 LYS K K 373 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 184 LYS K K 373 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 185 ASP D D 374 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 185 ASP D D 374 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 185 ASP D D 374 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 186 TYR Y Y 375 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 186 TYR Y Y 375 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 186 TYR Y Y 375 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 187 TYR Y Y 376 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 187 TYR Y Y 376 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 187 TYR Y Y 376 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 188 GLN Q Q 377 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 188 GLN Q Q 377 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 188 GLN Q Q 377 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 189 THR T T 378 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 189 THR T T 378 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 189 THR T T 378 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 190 PHE F F 379 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 190 PHE F F 379 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 190 PHE F F 379 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 191 LEU L L 380 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 191 LEU L L 380 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 191 LEU L L 380 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 192 THR T T 381 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 192 THR T T 381 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 192 THR T T 381 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 193 ASN N N 382 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 193 ASN N N 382 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 193 ASN N N 382 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 194 ASP D D 383 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 194 ASP D D 383 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 194 ASP D D 383 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 195 ASN N N 384 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 195 ASN N N 384 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 195 ASN N N 384 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 196 PRO P P 385 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 196 PRO P P 385 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 196 PRO P P 385 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 197 GLN Q Q 386 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 197 GLN Q Q 386 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 197 GLN Q Q 386 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 198 CYS C C 387 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 198 CYS C C 387 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 198 CYS C C 387 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 199 ILE I I 388 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 199 ILE I I 388 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 199 ILE I I 388 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 200 LEU L L 389 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 200 LEU L L 389 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 200 LEU L L 389 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 201 ASN N N 390 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 201 ASN N N 390 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 201 ASN N N 390 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 202 ALA A A 391 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 202 ALA A A 391 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 202 ALA A A 391 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
1 A 1 203 PRO P P 392 O57413 1 1 ? y 1 Pfam PF01421 ? 1 1
1 A 2 203 PRO P P 392 O57413 1 1 ? y 1 CATH 3.40.390.10 1kugA00 1 1
1 A 3 203 PRO P P 392 O57413 1 1 ? y 1 SCOP2 8040594 SCOP2B-SF 1 1
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